展期：2026-06-08~2026-06-15

6/19(五)端午節休館，敬祝大家佳節愉快

如何利用 Taiwan Biobank 資料進行代謝體學分析？
Phase１.由張中科博士先介紹代謝體學的背景、相關應用與 Taiwan Biobank 的相關資源
Phase２. 由吳性慧數據分析師帶領，以 R 語言搭配 MetaboAnalystR 套件進行分析實作

JoVE系列刊物，試用至 2026/06/17 日止，歡迎多加使用

ProQuest Dissertations & Theses Global試用至 2026/06/30 日止，歡迎多加使用

本書以「順其自然」為名，精心整合廿一篇來自中央研究院生物多樣性研究中心十一位研究人員及其研究團隊的文章。這些文章的內容豐富多元，涵蓋微生物、植物、鳥類、魚類、甲殼類、棘冠海星、珊瑚，乃至化石、火山浮石，以及動人的保育故事，期盼能與讀者一同探索自然的奧妙，共享這份來自大自然的饗宴。

生物成長時並非一味添加新細胞，有時候也需要動用減法，除去某些位置的細胞。

講題：Unusual Enzyme Reactions in Natural Product Biosynthesis
主講者：阿部郁朗教授 (日本東京大學)
時間：2026-06-09 11:00 - 12:00
地點：生化所209研討室

講題：Bench-to-Bedside: Decoding the PDAC Ecosystem to Drive AI Diagnostics and Precision Therapeutics
主講者：胡春美助研究員 (基因體研究中心)
時間：2026-06-10 10:30 - 11:30
地點：基因體研究中心一樓演講廳

講題：Coding or non-coding? Illuminating the “dark matter” of the proteome
主講者：Jin Chen教授 (美國Altos Labs Institute of Science)
時間：2026-06-11 11:00 - 12:00
地點：生化所209研討室

講題：Metabolic Programming in Early Life: Ketone Signaling and Epigenetic Control of Adipose Plasticity
主講者：林甫容 博士 (台大)
時間：2026-06-11 16:00 - 17:00
地點：生醫所地下室B1B演講廳

講題：Functional interaction of JMJ28 and GCN5 in regulating ABA and drought responses
主講者：Ms. Wen-Chi Liao (Institute of Plant and Microbial Biology, Academia Sinica)
時間：2026-06-12 10:30 - 11:30
地點：中央研究院植物暨微生物學研究所R106多功能會議室

講題：Genome-wide survey of ribosome collision in de-etiolating Arabidopsis
主講者：Dr. Yueh Cho (Institute of Plant and Microbial Biology, Academia Sinica)
時間：2026-06-12 10:30 - 11:30
地點：中央研究院植物暨微生物學研究所R106多功能會議室

講題：Exploring Cutting-Edge Advancements in Dementia Treatment
主講者：胡朝榮 院長 (臺北醫學大學)
時間：2026-06-12 11:00 - 12:00
地點：基因體研究中心一樓演講廳

講題：Plant-microbe-climate interactions in the phyllosphere
主講者：Dr. Sheng Yang He (Duke University, USA)
時間：2026-06-15 15:00 - 16:00
地點：中央研究院農業科技大樓 A134演講廳

講題：Phase separation in telomere maintenance of ALT cancers
主講者：Huaiying Zhang教授 (美國Carnegie Mellon University)
時間：2026-06-16 11:00 - 12:00
地點：生化所209研討室

講題：Targeting Lipid Metabolism in Pancreatic Cancer
主講者：鄭嘉樂 (Uni. of Michigan Medical Scientist Training Program)
時間：2026-06-16 11:00 - 12:00
地點：生醫所地下室B1B演講廳

講題：Engineering Longevity - Computationally-guided reprogramming of single-cell aging
主講者：Dr. Nan Hao (University of California, San Diego)
時間：2026-06-16 11:00 - 12:00
地點：中央研究院分子生物研究所一樓演講廳

講題：Arrested Development temporal regulation of cell identity during plant embryogenesis
主講者：Dr. Margot Smit (ZMBP, Tübingen University, Germany)
時間：2026-06-17 11:00 - 12:20
地點：中央研究院農業科技大樓 A134演講廳

講題：Protein biogenesis and quantity control at the ribosome
主講者：Zhewang Lin教授 (新加坡國立大學)
時間：2026-06-22 11:00 - 12:00
地點：生化所209研討室

Our results suggest that FUT8 in platelets may be a therapeutic target for thrombosis-related cardiovascular diseases

Herein, we present a ZnCl2-promoted coupling of exo-glycals and arylamines for the stereospecific synthesis of (1S)-spiro-tetrahydroquinoline glycosides in a one-pot fashion.

BRCA1-associated protein 1 (BAP1) is a tumor suppressor whose deubiquitinase (DUB) activity is essential for transcriptional regulation and is frequently compromised in cancer by mutations clustered in its ubiquitin carboxyl-terminal hydrolase (UCH) domain.

This study aimed to improve SN38 delivery using poly(lactic-co-glycolic acid) (PLGA) nanoparticles and to evaluate their efficacy and safety in vitro and in a murine colitis-associated CRC model.

Our tool offers a timely, cost-effective approach to rapidly identifying high-affinity binders from large candidate pools, thus facilitating state-of-the-art protein design

We supply algorithms to transform between states. This preserves interoperability across diverse organelles, media and between enzymology and chemical engineering, while facilitating reuse.

微型神經探針是腦科學研究與腦機介面技術的重要工具，這項成果為設計更安全、低創傷、高密度的神經植入裝置提供了量化依據。

Here, we present near-atomic-resolution cryogenic electron microscopy structures of Suv3 captured in four functional states: the apo form, two binary complexes with ADP and single-stranded RNA (ssRNA), and a ternary complex with ssRNA and an ATP analog (AMP-PNP).

These findings provide a structural framework for designing Siglec-targeted immunotherapies against chronic viral infections and immune disorders.