訂/退閱   English
生圖臉書 生圖 Youtube 生圖 Blog 生圖 IG
 發報日期 : 2025/09/15 發行期數:369 
 
 
 

最新消息

 
 
 
 
新書展示
 
展期:2025-09-15~ 2025-09-22
 
 
 
 
 
 
 
歡迎報名線上講座:Springer期刊投稿線上講座—學術期刊出版流程及投稿技巧
 
時 間:2025年9月18日星期四下午2:30-3:30
題 目:學術期刊出版流程及投稿技巧
主講者:胡睿琦 Springer Nature副編輯
 
 
 
 
 
 
 
2025 院區開放系列活動
 
2025/10/19 院區開放日
2025/10/19 兒童科普日
2025/11/08 南院開放日
 
 
 
 
 
 

教育訓練課程

 
 
 
【生物資訊系列】GWAS入門與進階應用:走進基因與疾病的橋樑(In Chinese)(實體課程)
 
2025-09-18(四)13:30~17:00
熊嘉妮小姐(國立清華大學)
國家生技園區D棟二樓電腦教室
 
 
 
 
【臨床試驗系列】第1講—臨床試驗之基本概念(In Chinese)(實體+線上課程)
 
2025-09-23(二)10:00~12:00
王玫博士(資料科學統計合作社專家學者/財團法人醫藥品查驗中心資深統計審查員)
環境變遷大樓 6005 教室
 
 
 
 
 
 
【生圖資源篇】活用 TAIR 於植物研究:阿拉伯芥與作物的實用工具(In Chinese)(實體+線上課程)
 
2025-09-25(四)10:00~12:00
陳荷明博士(副研究員,農生中心)
農科大樓 A133 會議室
 
 
 
 
【生物資訊系列】Alternative-splicing detection by NGS (In English)(實體+線上課程)
 
2025-09-30(二)14:00~16:00
林文鐽博士(研究副技師,植微所)
環境變遷大樓 6005 教室
 
 
 
 
   
 
 
 

影音服務

 
 
 
 
新增課程之影音及講義,歡迎線上瀏覽
 
9/2-Gene annotation and orthology assignment for newly-sequenced organisms(In Chinese)
9/9-當你遇到生圖,研究好上手!(In Chinese)
9/10-Turnitin 教師工具箱(含 AI 寫作偵測)(In Chinese)
9/12-Ingenuity Pathway Analysis (IPA) 前沿應用工作坊:多組學腫瘤案例(FAP)+實際藥物毒性機轉(APAP)整合分析(In English)
9/16-善用生醫影音資源-從理論到實作(In Chinese)
 
 
 
 
 
 

Blog

 
 
 
 
淺談水母
 
水母生態特性與演化奧秘簡介
 
 
 
 
 
 

專題報導

 
 
 
 
以終為始的轉譯研究:推動創新研究成果到臨床應用
 
轉譯研究的本質,是將實驗室的創新成果,實際轉化為能解決臨床問題的治療產品。
 
 
 
 
 
 

生命組演講公告

 
 
 
 
09/17 植微所演講
 
講題:Rhizoctonia Genomics: Sclerotia-forming capability and fungicide resistance
主講者:張皓巽副教授 (國立臺灣大學植物病理與微生物學系)
時間:2025-09-17 11:00 - 13:00
地點:中央研究院植物暨微生物學研究所農業科技大樓 A134演講廳
 
 
 
 
 
 
 
09/18 生醫所演講
 
講題:TRIB2 deficiency enhances thermogenesis and prevents obesity by impairing the recruitment of MYCBP2 E3 ligase to degrade UCP1
主講者:張以承 博士 (合聘副研究員)
時間:2025-09-18 16:00 - 17:00
地點:生醫所地下室B1B演講廳
 
 
 
 
 
 
 
09/19 分生所演講
 
講題:IMB Founders Lectureship: Experimental Evolution and Physiology in the Brewer’s Yeast
主講者:Dr. Andrew W. Murray (Herchel Smith Professor of Molecular Genetics, Harvard Universit
時間:2025-09-19 14:30 - 16:00
地點:中央研究院分子生物研究所B1演講廳
 
 
 
 
 
 
 
09/22 細生所演講
 
講題:Unraveling Vesicle Trafficking in the Spatiotemporal Coordination of Collective Cell Migration
主講者:張純純教授 (國立成功大學)
時間:2025-09-22 11:00 - 12:30
地點:細生所演講廳
 
 
 
 
 
 
 
09/22 農生中心演講
 
講題:Cell-cell communications with peptide hormone-receptor pairs in various plants
主講者:Dr. Hidefumi Shinohara (Associate Professor, Faculty of Bioscence and Biotechnology, Fukui Prefectural University, JAPAN)
時間:2025-09-22 11:00 - 13:00
地點:農科大樓1樓A134演講廳
 
 
 
 
 
 
 
09/22 植微所演講
 
講題:Reproductive “isolation” on fern leaves: Evolution of dimorphic syndromes in the genus Tectaria
主講者:郭立園副教授(台灣清華大學)
時間:2025-09-22 15:00 - 17:00
地點:中央研究院植物暨微生物學研究所農業科技大樓 A134演講廳
 
 
 
 
 
 
 
09/22 生多中心演講
 
講題:New Frontiers in Fungal Ecology: Partnerships Beyond the Seed Plant Realm
主講者:陳可萱助研究員 (本院生物多樣性研究中心)
時間:2025-09-22 15:00 - 16:30
地點:跨領域科技研究大樓1樓演講廳
 
 
 
 
 
 
 
09/23 分生所演講
 
講題:Nonsense-mediated mRNA decay in human health and disease
主講者:Dr. Lynne Maquat (J. Lowell Orbison Endowed Chair and Professor, Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester)
時間:2025-09-23 13:30 - 14:30
地點:中央研究院分子生物研究所B1演講廳
 
 
 
 
 
 
 
09/24 植微所演講
 
講題:Spatiotemporal dynamics of glycerolipid metabolism in plant growth control
主講者:Dr. Yuki Nakamura (Team Director, RIKEN Center for Sustainable Resource Science (CSRS), Japan)
時間:2025-09-24 15:00 - 17:00
地點:中央研究院植物暨微生物學研究所農業科技大樓 A134演講廳
 
 
 
 
 
 
 
09/24 植微所演講
 
講題:Development of EGAO (Ethanol-based Global Agricultural Optimization) technology and its application for the carbon-neutral sustainable agriculture
主講者:Dr. Motoaki Seki (Team Director, RIKEN Center for Sustainable Resource Science (CSRS), Japan)
時間:2025-09-24 15:00 - 17:00
地點:中央研究院植物暨微生物學研究所農業科技大樓 A134演講廳
 
 
 
 
 
 
 
09/26 植微所演講
 
講題:ROC & ROL on mobile mRNA: the hitchhiker’s guide to the plasmodesmata
主講者:余天心研究員(中央研究院植物暨微生物學研究所)
時間:2025-09-26 11:00 - 12:00
地點:中央研究院植物暨微生物學研究所農業科技大樓 A134演講廳
 
 
 
 
 
 
 
09/30 生醫所演講
 
講題:Targeting Adipocytes to Combat Metabolic Cardiovascular Disease: A Translational Approach
主講者:馬新亮 博士 (Thomas Jefferson Univ.)
時間:2025-09-30 14:00 - 15:00
地點:生醫所地下室B1A演講廳
 
 
 
 
 
 
 
10/03 生多中心演講
 
講題:Right Traits, Right Time, Right Mountains: Natural Experiments in Berberis Diversification
主講者:游旨价 博士(Field Museum of Natural History, Chicago, USA)
時間:2025-10-03 10:00 - 11:30
地點:跨領域科技研究大樓1樓演講廳
 
 
 
 
 
 
 
10/07 生醫所演講
 
講題:CD27 Agonism Enhances Long-Lived CD4⁺ T Cell Vaccine Responses Critical for Anti-Tumor Immunity
主講者:黃秉鈞 博士 (Duke Univ.)
時間:2025-10-07 11:00 - 12:15
地點:生醫所地下室B1B演講廳
 
 
 
 
 
 
 
10/13 植微所演講
 
講題:Motility and life clarified by minimal synthetic bacterium, JCVI-syn3
主講者:Prof. Makoto Miyata (Department of Biology, Osaka Metropolitan University, Japan)
時間:2025-10-13 11:00 - 13:00
地點:中央研究院植物暨微生物學研究所農業科技大樓 A134演講廳
 
 
 
 
 
 
 
10/13 農生中心演講
 
講題:Understanding Resistance and Susceptibility to Downy Mildew: Mechanisms, Trade-offs, and Translation to Breeding
主講者:Prof. Guido Van den Ackerveken (Chair and Professor of Translational Plant Biology, Department of Biology, Utrecht University, Netherlands;Scientific Director of CropXR, Utrecht, Netherlands)
時間:2025-10-13 14:00 - 16:00
地點:本院農科大樓一樓A134演講廳
 
 
 
 
 
 

生命組研究成果重要發現

 
 
 
 
Gut microbiota-derived formate exacerbates pulmonary metastasis in cancer
 
Microbiota-derived formate plays a critical role in enhancing pulmonary metastasis by modulating cancer cell metabolism.
 
 
 
 
 
 
 
Narrowband Ultraviolet B Induces Peripheral Regulatory T Cells to Exert Antigen-Specific Immune Suppression
 
Our findings suggest UVB can induce antigen-specific Tregs in a clinical setting, highlighting its potential for broader immunosuppressive applications.
 
 
 
 
 
 
 
Galectins in Inflammatory Skin Diseases: Mechanisms and Therapeutic Potential
 
By synthesizing current research, this review underscores the opportunities for further studies to clarify the regulatory mechanisms of galectins in skin inflammation, aiming to enhance therapeutic strategies.
 
 
 
 
 
 
 
Hypoxia‑induced genome‑wide DNA demethylation by DNMT3A and EMT of cancer cells
 
Our findings have revealed a missing link between the HIF-1α pathway and the O2-sensing KDM pathway. Finally, the active DNA demethylation activity of DNMT3A has now emerged as a new potential target for therapeutic development to prevent EMT and metastasis of cancer cells.
 
 
 
 
 
 
 
Comprehensive analysis of repetitive extragenic palindrome sequences identified in bacteria and archaea using a new web-based tool, RepRanger
 
We demonstrate that RepRanger represents a versatile tool for discovering REPs in bacteria and archaea, providing new insights into their functions and sequence diversity.
 
 
 
 
 
 
 
Structural Dissection of Vaccinia G9 Identifies Residues Essential for Membrane Fusion and Complex Assembly
 
These results establish G9 as a central EFC component and underscore its potential as a target for antiviral development.
 
 
 
 
 
 
 
New mechanistic insights into Prp22-mediated exon ligation and mRNA release
 
These findings change the current view of splicing fidelity control and offer new mechanistic insights into Prp22-mediated mRNA release. The paper is recognized as Breakthrough Article by NAR.
 
 
 
 
 
 
 
The RNA degradation enzyme RNase E is essential for early flagellar assembly in Escherichia coli
 
These results identify RNase E as a key flagellar biogenesis regulator, revealing novel posttranscriptional control mechanisms.
 
 
 
 
 
 
 
Rad51, Rad54, and ZMM proteins antagonize the mismatch repair system to promote fertility of budding yeast intraspecies hybrid zygotes
 
本研究重塑我們對減數分裂、DNA修復、優生育種、生物演化與癌症治療的理解。
 
 
 
 
 
 
 
脊索動物的起源:驅動脊索出現的古老基因調控密碼
 
此研究揭示在演化過程中,調控模組能以密碼的形式被保存下來,並加以利用產生新功能。
 
 
 
 
 
 
 
環境與菌株差異塑造農桿菌在植物中的基因調控
 
這項研究顯示,若要全面理解農桿菌的生物學並提升轉殖效率,研究必須在真實的植物環境中進行,並涵蓋不同菌株,以突破過去依賴人工培養條件與模式菌株的侷限,同時也為未來應用開啟新的契機。
 
 
 
 
 
 
 
TISCalling:應用機器學習預測植物與病毒的轉譯起始位點之方法
 
研究團隊開發了一套名為 TISCalling 的生物資訊工具,旨在識別和鑑定真核生物及病毒基因組中的轉譯起始位點 (translational initiation sites, TISs)。
 
 
 
 
 
 
 
發現阿拉伯芥根部金屬螯合劑分泌運輸蛋白ENA1,開啟植物金屬調控新篇章
 
揭示植物對重金屬調控的嶄新機制,也為植物修復污染土壤(phytoremediation)與提升作物營養價值(biofortification)提供關鍵基礎。
 
 
 
 
 
 
 
Transposable elements drive evolution and perturb gene expression in Brassica rapa and B. oleracea
 
顯示轉座子具備潛在的調控功能。這些發現不僅深化了我們對轉座子如何塑造作物基因體演化的理解,也凸顯了其在作物育種與基因體工程上的應用潛力。
 
 
 
 
 
 
 
Revisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
 
This work therefore not only demonstrates that hOgg1 is well suited for time-resolved crystallography, but also that such analysis is necessary to determine further steps in its reaction.
 
 
 
 
 
 
 
Multiplex bead immunoassay in ABO-A2-incompatible kidney transplantation
 
Our ABO antibody assay reproducibly measures graft-specific anti-A-II antibodies, providing information beyond anti-A titers that may increase transplant access for ABO-B and ABO-O candidates.
 
 
 
 
 
 
 
 
  電話:(02) 2789-9829
地址:臺北市南港區研究院路二段128號(生態時代館)
@2021 Academia Sinica Life Science Library e-News Paper, All Rights Reserved