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In this work, we introduced in Arabidopsis thaliana a new-to-nature CO2 fixing cycle, malyl-CoA-glycerate (McG) cycle, which together with the CBB cycle forms a dual-cycle CO2 fixation system. |
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Self-complementing bipartite fluorescent proteins (FPs) are useful tools for the detection of protein-protein proximity and for localizing fluorophores to membrane-membrane contact sites. |
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Flaviviruses contain many important human pathogens such as dengue virus (DENV) and Zika virus (ZIKV).Our results demonstrate the effectiveness of rAAV in delivering bnAb 752-2C8 for long-term protection against multiple flaviviruses, providing a potential strategy to control flavivirus infections and possibly other viral diseases. |
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A 15-year prospective study of CHC patients with SVRs was conducted. |
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This study provides a comprehensive overview of the evolutionary dynamics of H10 avian influenza viruses isolated from wild birds in Taiwan, emphasizing the complexity of intercontinental gene flow and viral reassortment. |
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The genetic and molecular basis of asthma remains unclear and its gene-environment interaction is still enigmatic. In the present study, we aimed to identify asthma-causing genetic variants and their interactions with the environment. |
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Amyloid precursor protein (APP) plays a key role in the pathogenesis of Alzheimer’s disease (AD). |
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Our data demonstrate that serotonin modulates HTR2A, attenuating psoriatic inflammation by suppressing IL-23 secretion via inhibiting the non-canonical NFκB pathway in moLCs. |
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Our results support what we believe to be a novel mechanism by which a mutation in a single Calm gene can give rise to a severe phenotype. |
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Our results indicate that targeting the extracellular matrix can increase the antitumor activity of some nanomedicines, but that careful selection of compatible nanomedicines is necessary. |
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During a critical period of postnatal brain development, neural circuits undergo significant refinement coincident with widespread alternative splicing of hundreds of genes, which undergo altered splice site selection for the generation of isoforms essential for synaptic plasticity. |
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此研究首次將一合成的固碳McG循環 (McG) 置入植物中與既有的卡爾文循環 (CBB) 共同運作，形成前所未有的「雙固碳系統」(Dual-cycle carbon fixation)。 |
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這項研究提供了首個支持鳥蛋重量與鳥巢結構演化連結的全面性證據。我們的發現闡明，生物特徵的演化可以源自一個簡單的物理機制。 |
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結合結構與功能層面的研究方法，將是破解效應蛋白作用機制、深入理解黑穗菌與寄主之間分子軍備競賽的關鍵，最終可為發展持久的作物抗病策略提供重要指引。 |
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AF3 為植物科學開啟了新的可能，不只加快蛋白質研究，也有望推動作物育種與合成生物學的發展。 |
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我們的研究結果表明，蝴蝶蘭氣生根的生長方向主要受向水性，而非向光性或向地性影響。此向水性反應可能是附生蘭花得以有效利用森林冠層水源的重要適應策略。 |
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