展期：2024-3-4 ~ 2024-3-11

展出日期：2023/10/14~2024/03/31
展出時間：週一至週五 08:30 ~ 18:00 (國定例假日除外)

錢鼠又叫作臭鼩，是真盲缺目鼩鼱科(又稱尖鼠科)的動物，牠們的四肢短小嘴巴比老鼠更為尖長。囓齒目的鼠類上下顎各有會不斷增生的門牙，必須依靠到處咬咬來持續磨短門牙；但真盲缺目動物則不具有這樣的牙齒。

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講題：Life's Tiny Giants: Unveiling the Vital Role of Plankton in the Aquatic Food Webs
主講者：陳家婷博士
時間：2024-03-05 10:00 - 11:00
地點：細胞與個體生物學研究所1樓演講廳

講題：Life cycle control in flowering plants and beyond
主講者：Dr. Michael Borg (Group Leader, Max Planck Institute for Biology, Tübingen, Germany)
時間：2024-03-05 11:00 - 12:00
地點：中央研究院植物暨微生物學研究所農業科技大樓A134演講廳

講題：Molecular mechanisms of Arl1 GTPase regulation in vesicular trafficking
主講者：李芳仁 特聘教授 (國立臺灣大學)
時間：2024-03-06 10:30 - 12:00
地點：基因體研究中心一樓演講廳

講題：Emerging technologies for Green Transition
主講者：Irini Angelidaki教授 (丹麥Technical University of Denmark)
時間：2024-03-06 14:00 - 15:00
地點：生化所209研討室

講題：Local and global regulation of neural circuit by astrocytes
主講者：Dr. Jun Nagai (Team Leader (PI), Lab for Glia-Neuron Circuit Dynamics Developmental Biology, RIKEN Center for Brain Science)
時間：2024-03-07 11:00 - 12:00
地點：中央研究院分子生物研究所1F演講廳

講題：Decoding Root Growth to Mitigate Climate Change
主講者：Dr. Wolfgang Busch (Professor, Hess Chair in Plant Science, Plant Molecular And Cellular Biology Laboratory, Integrative Biology Laboratory, Salk Institute for Biological Studies, USA)
時間：2024-03-11 11:00 - 12:00
地點：本院農科大樓1樓A134演講廳

講題：Mechanosensitive Nuclear Pores
主講者：Dr. Martin Beck (Director, Max Planck Institute of Biophysics Frankfurt, Germany)
時間：2024-03-12 11:00 - 12:00
地點：中央研究院分子生物研究所B1演講廳

講題：Brain Bank for Aging Research: Molecular, Dynamic and Statistical Neuropathology, on Brain Donation System, with BioBank Japan
主講者：Shigeo Murayama教授 ( Osaka Univ.)
時間：2024-03-12 11:00 - 12:00
地點：跨領域大樓一樓演講廳

講題：Functional neuronal circuits emerge in the absence of developmental activity
主講者：Dr. Florian Engert (Professor, Molecular and Cellular Biology, Harvard University)
時間：2024-03-14 11:00 - 12:00
地點：中央研究院分子生物研究所B1演講廳

講題：Borono-lectin”-inspired chemistry platform for bio-interactive DDS
主講者：松元亮 博士 (The Univ. of Tokyo)
時間：2024-03-14 16:00 - 17:00
地點：生醫所地下室B1B演講廳

講題：From Molecular Biology to Biotech CEO
主講者：Dr. 周慧泉 (President and Chief Executive Officer AltruBio, Inc.)
時間：2024-03-15 10:00 - 11:00
地點：中央研究院分子生物研究所B1演講廳

講題：Chemo-enzymatic transformation of carbohydrates and glycosides towards the syntheses of bioactive substances
主講者：Takeshi Sugai教授 (日本慶應義塾大學)
時間：2024-03-15 11:00 - 12:00
地點：生化所209研討室

講題：Mini-Symposium on Neurobiology
主講者：Dr. Thomas Lloyd、Dr. Dion Dickman、Dr. Cheng-Ting Chien等人
時間：2024-03-05 09:30 - 17:50
地點：跨領域大樓一樓演講廳

講題：2024美國史丹佛大學-高雄醫學大學-中央研究院共同舉辦iPS幹細胞與再生醫學國際研討會: 從基礎研究到精準醫學
主講者：請見活動內容
時間：2024-03-11 09:00 - 16:50
地點：生醫所地下室B1C演講廳

講題：第一屆台灣循環研究學會國際研討會: 整合基礎研究與臨床轉譯
主講者：請見活動內容
時間：2024-03-12 08:20 - 17:00
地點：生醫所地下室B1C演講廳

講題：生物過程中的生物分子凝聚體
主講者：請見活動內容
時間：2024-03-14 13:00 - 17:30
地點：生醫所地下室B1C演講廳

The theories for substrate recognition in enzyme catalysis have evolved from lock-key to induced fit, then conformational selection, and conformational selection followed by induced fit. However, the prevalence and consensus of these theories require further examination.

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Most membrane proteins are modified by covalent addition of complex sugars through N- and O-glycosylation. Unlike proteins, glycans do not typically adopt specific secondary structures and remain very mobile, shielding potentially large fractions of protein surface.

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Many genes with distinct molecular functions have been linked to genetically heterogeneous amyotrophic lateral sclerosis (ALS), including SuperOxide Dismutase 1 (SOD1) and Valosin-Containing Protein (VCP). SOD1 converts superoxide to oxygen and hydrogen peroxide.

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Serine(S)/threonine(T)-glutamine(Q) cluster domains (SCDs), polyglutamine (polyQ) tracts and polyglutamine/asparagine (polyQ/N) tracts are Q-rich motifs found in many proteins. SCDs often are intrinsically disordered regions that mediate protein phosphorylation and protein-protein interactions.

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Long noncoding RNAs (lncRNAs) play pivotal roles in modulating gene expression during development and disease. Despite their high expression in the central nervous system (CNS), understanding the precise physiological functions of CNS-associated lncRNAs has been challenging, largely due to the in vitro-centric nature of studies in this field.

UFMylation is an emerging ubiquitin-like post-translational modification that regulates various biological processes. Dysregulation of the UFMylation pathway leads to human diseases, including cancers.

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Nanoparticles, especially gold nanoparticles (GNPs) have emerged as promising tools for biomedical applications due to their unique properties and ability to be functionalized. However, quantitative analysis of biomolecules conjugated to nanoparticles remains a challenge.

Non-small cell lung cancer (NSCLC), a major life-threatening disease accounting for 85% of all lung cancer cases, has been treated with tyrosine kinase inhibitors (TKIs), but often resulted in drug resistance, and approximately 60% of TKI-resistant cases are due to acquired secondary (epithelial growth factor receptor) EGFR-T790M mutation.

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