Period: 2024-3-4 ~ 2024-3-11

Topic：Life's Tiny Giants: Unveiling the Vital Role of Plankton in the Aquatic Food Webs
Speaker：Dr. Chia-Ting Chen
Date：2024-03-05 10:00 - 11:00
Place：Auditorium, 1st Floor, Institute of Cellular and Organismic Biology

Topic：Life cycle control in flowering plants and beyond
Speaker：Dr. Michael Borg (Group Leader, Max Planck Institute for Biology, Tübingen, Germany)
Date：2024-03-05 11:00 - 12:00
Place：Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica

Topic：Molecular mechanisms of Arl1 GTPase regulation in vesicular trafficking
Speaker：Fang-Jen (Scott) Lee, Distinguished Professor (National Taiwan University)
Date：2024-03-06 10:30 - 12:00
Place：1F Auditorium, Genomics Research Center

Topic：Emerging technologies for Green Transition
Speaker：Dr. Irini Angelidaki (Technical University of Denmark, Denmark)
Date：2024-03-06 14:00 - 15:00
Place：IBC R209

Topic：Local and global regulation of neural circuit by astrocytes
Speaker：Dr. Jun Nagai (Team Leader (PI), Lab for Glia-Neuron Circuit Dynamics Developmental Biology, RIKEN Center for Brain Science)
Date：2024-03-07 11:00 - 12:00
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Decoding Root Growth to Mitigate Climate Change
Speaker：Dr. Wolfgang Busch (Professor, Hess Chair in Plant Science, Plant Molecular And Cellular Biology Laboratory, Integrative Biology Laboratory, Salk Institute for Biological Studies, USA)
Date：2024-03-11 11:00 - 12:00
Place：Auditorium A134, Agricultural Technology Building

Topic：Mechanosensitive Nuclear Pores
Speaker：Dr. Martin Beck (Director, Max Planck Institute of Biophysics Frankfurt, Germany)
Date：2024-03-12 11:00 - 12:00
Place：B1 Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Brain Bank for Aging Research: Molecular, Dynamic and Statistical Neuropathology, on Brain Donation System, with BioBank Japan
Speaker：
Date：2024-03-12 11:00 - 12:00
Place：1F Auditorium (B106), IST

Topic：Functional neuronal circuits emerge in the absence of developmental activity
Speaker：Dr. Florian Engert (Professor, Molecular and Cellular Biology, Harvard University)
Date：2024-03-14 11:00 - 12:00
Place：B1 Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Borono-lectin”-inspired chemistry platform for bio-interactive DDS
Speaker：Dr. Akira Matsumoto (The Univ. of Tokyo)
Date：2024-03-14 16:00 - 17:00
Place：B1B Lecture Room, IBMS

Topic：From Molecular Biology to Biotech CEO
Speaker：Dr. Judy H. Chou (President and Chief Executive Officer AltruBio, Inc.)
Date：2024-03-15 10:00 - 11:00
Place：B1 Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Chemo-enzymatic transformation of carbohydrates and glycosides towards the syntheses of bioactive substances
Speaker：Dr. Takeshi Sugai (Keio University, Japan)
Date：2024-03-15 11:00 - 12:00
Place：IBC R209

Topic：Mini-Symposium on Neurobiology
Speaker：Dr. Thomas Lloyd、Dr. Dion Dickman、Dr. Cheng-Ting Chien, etc.
Date：2024-03-05 09:30 - 17:50
Place：1F Auditorium (B106), IST

Topic：2024 Stanford-Taiwan Symposium on iPSC and Regenerative Medicine: Bridging Basic Biology and Precision Medicine
Speaker：Please visit the website for more information
Date：March 11 th, 2024 (Monday) 09:00 - 16:50
Place：B1C Hall, IBMS, Academia Sinica, Taipei, Taiwan

Topic：1 st International Meeting of Taiwan Circulation Research Society: Integrating Basic Biology and Clinical Translation
Speaker：
Date：March 12 th, 2024 (Tuesday) 08:20 - 17:00
Place：B1C Hall, IBMS, Academia Sinica, Taipei, Taiwan

Topic：Biomolecular Condensates in Biological Processes
Speaker：Please visit the website for more information
Date：2024-03-14 13:00 - 17:30
Place：B1C Auditorium, IBMS

The theories for substrate recognition in enzyme catalysis have evolved from lock-key to induced fit, then conformational selection, and conformational selection followed by induced fit. However, the prevalence and consensus of these theories require further examination.

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Most membrane proteins are modified by covalent addition of complex sugars through N- and O-glycosylation. Unlike proteins, glycans do not typically adopt specific secondary structures and remain very mobile, shielding potentially large fractions of protein surface.

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Many genes with distinct molecular functions have been linked to genetically heterogeneous amyotrophic lateral sclerosis (ALS), including SuperOxide Dismutase 1 (SOD1) and Valosin-Containing Protein (VCP). SOD1 converts superoxide to oxygen and hydrogen peroxide.

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Serine(S)/threonine(T)-glutamine(Q) cluster domains (SCDs), polyglutamine (polyQ) tracts and polyglutamine/asparagine (polyQ/N) tracts are Q-rich motifs found in many proteins. SCDs often are intrinsically disordered regions that mediate protein phosphorylation and protein-protein interactions.

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Long noncoding RNAs (lncRNAs) play pivotal roles in modulating gene expression during development and disease. Despite their high expression in the central nervous system (CNS), understanding the precise physiological functions of CNS-associated lncRNAs has been challenging, largely due to the in vitro-centric nature of studies in this field.

UFMylation is an emerging ubiquitin-like post-translational modification that regulates various biological processes. Dysregulation of the UFMylation pathway leads to human diseases, including cancers.

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Nanoparticles, especially gold nanoparticles (GNPs) have emerged as promising tools for biomedical applications due to their unique properties and ability to be functionalized. However, quantitative analysis of biomolecules conjugated to nanoparticles remains a challenge.

Non-small cell lung cancer (NSCLC), a major life-threatening disease accounting for 85% of all lung cancer cases, has been treated with tyrosine kinase inhibitors (TKIs), but often resulted in drug resistance, and approximately 60% of TKI-resistant cases are due to acquired secondary (epithelial growth factor receptor) EGFR-T790M mutation.

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