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N-乙醯葡萄糖胺（GlcNAc）是一種基礎氨基醣，對於蛋白質、脂質的醣基化以及細胞壁組成分至關重要。UDP-GlcNAc是活化態的GlcNAc，能夠透過己醣胺生合成途徑（hexosamine biosynthesis pathway, HBP）合成。 |
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Ovarian carcinoma is usually diagnosed at an advanced stage with peritoneal dissemination and/or lymph node metastasis, and the prognosis for such advanced carcinoma is very poor. |
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Prions, the misfolding form of prion proteins, are contagious proteinaceous macromolecules. Recent studies have shown that infectious prion fibrils formed in the brain and non-infectious fibrils formed from recombinant prion protein in a partially denaturing condition have distinct structures. |
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Mycobacterium abscessus is increasingly recognized as the causative agent of chronic pulmonary infections in humans. One of the genes found to be under strong evolutionary pressure during adaptation of M. abscessus to the human lung is embC which encodes an arabinosyltransferase required for the biosynthesis of the cell envelope lipoglycan, lipoarabinomannan (LAM). |
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The capability to sense and respond to the environment is essential for survival and fitness in all organisms. Recent studies have shown organisms from different kingdoms, such as fungi, plants, and mammals can recognize and respond to conserved nematode pheromones, named ascarosides. However, the mechanisms underlying cross kingdom perception of nematode pheromones remain unclear. |
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Root architecture and function are critical for plants to secure water and nutrient supply from the soil, but environmental stresses alter root development. The phytohormone jasmonic acid (JA) regulates plant growth and responses to wounding and other stresses, but its role in root development for adaptation to environmental challenges had not been well investigated. |
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Metabolic syndrome (MetS) is a collection of cardiovascular risk factors; however, the high prevalence and heterogeneity impede effective clinical management. |
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