展期:2025-09-01~ 2025-09-08

Turnitin的英文 AI 寫作偵測功能為輔助工具，旨在協助教育者、研究人員與出版單位辨識文稿中可能由 AI 產生的文字內容：包含由ChatGPT 等生成式 AI 工具所撰寫、或是將 AI 文字進一步以 AI 編寫器二次改寫，從而了解文稿的原創性與真實性。

資料科學統計合作社與生命科學圖書館誠摯邀請您，參與「臨床試驗」系列課程。本課程專為醫療、生技與學術研究領域的專業人士設計，旨在提供從試驗設計到數據分析的全面訓練。
課程時間：2025年9月23日至2026年2月24日
地點：中研院環境變遷研究大樓 6005 教室

Turnitin的英文 AI 寫作偵測功能為輔助工具，旨在協助教育者、研究人員與出版單位辨識文稿中可能由 AI 產生的文字內容：包含由ChatGPT 等生成式 AI 工具所撰寫、或是將 AI 文字進一步以 AI 編寫器二次改寫，從而了解文稿的原創性與真實性。

中央研究院「研之有物」專訪院內生物化學研究所所長呂桐睿特聘研究員（Dr. Todd Lowary），為了理解結核病的根源，他致力研究結核分枝桿菌細胞壁的多醣結構，本文可以看到他如何將醣化學應用在結核病診斷，並為將來疫苗的研發建立了生化基礎。

講題：The multifaceted role of redox metabolism in cancer: from cell-autonomous actions to tumor microenvironment
主講者：張志禎博士 (助研究員, 中央研究院基因體研究中心)
時間：2025-09-02 11:00 - 12:00
地點：中央研究院分子生物研究所一樓演講廳

講題：Advancing cardiac therapeutics from animals to patients
主講者：Dr. Eldad Tzahor (Weizmann Inst. of Science)
時間：2025-09-04 10:00 - 11:00
地點：生醫所地下室B1C演講廳

講題：Formation and Mal-Formations of the Vasculature: From Development to Disease
主講者：Dr. Karina Yaniv (Weizmann Inst. of Science)
時間：2025-09-04 11:00 - 12:00
地點：生醫所地下室B1C演講廳

講題：The Roles of RNA-Binding Proteins and RNA Damage in Genome Stability and Chemotherapeutic Responses
主講者：陳榮貴 博士 (台大)
時間：2025-09-04 15:00 - 16:15
地點：生醫所地下室B1B演講廳

講題：DNA encoded techniques to study glycomics
主講者：Ratmir Derda教授 (加拿大阿爾伯塔大學)
時間：2025-09-05 11:00 - 12:00
地點：生化所209研討室

講題：Cardiac Regeneration: Transcriptional Control and a New Model Organism
主講者：Dr. Kazu Kikuchi (日本國立循環器病研究中心)
時間：2025-09-08 11:00 - 12:00
地點：細生所演講廳

講題：Beyond Degradation: E3 Ubiquitin Ligases in Heat Stress and Flowering Time Regulation
主講者：Assistant Professor Chin-Mei Lee (Institute of Plant Biology, National Taiwan University, Taiwan)
時間：2025-09-09 11:00 - 13:00
地點：中央研究院植物暨微生物學研究所農業科技大樓 A134演講廳

講題：如何給個有效的演講：該做好的和不該犯的錯誤
主講者：張典顯 研究員 (基因體研究中心)
時間：2025-09-11 10:00 - 11:50
地點：基因體研究中心一樓演講廳

主題演講嘉賓：
Dr. Ann-Shyn Chiang, National Tsing Hua University, TW
Dr. Rohini Kuner, Heidelberg University, DE
Dr. Chih-Cheng Chen, Academia Sinica, TW
Dr. Shuu-Jiun Wang, National Yang Ming Chiao Tung University, TW
時間：2025-09-02 17:00 ~ 2025-09-03 17:00
地點：生醫所地下室B1C演講廳

Commonly used to treat inflammatory skin diseases, narrowband ultraviolet B (UVB) has been shown to induce antigen-specific immune suppression when combined with alloantigen immunization, but the underlying mechanism remains elusive.Our findings suggest UVB can induce antigen-specific Tregs in a clinical setting, highlighting its potential for broader immunosuppressive applications.

This report illuminates the path for future development of LiGA-based serological assays and suggests the need to develop alternative methods for conjugating glycans to phage to avoid liabilities of the hydrophobic DBCO moiety.

We demonstrate that aggregation is dependent on the Pel polysaccharide and that Pel production allows bacteria not only to persist longer during infection but also modulates the immune responses of the host.

Here, we fully elucidate the biosynthesis of (-)-asperpentyn (2) through heterologous reconstitution in Aspergillus oryzae, chemical synthesis, chiral analysis, and biochemical assays.

In this study, we report three early-onset epilepsy cases with de novo missense mutations in Shaker-type channel genes, including Kv1.3, KCNA4 (Kv1.4), and Kv1.6, identified through whole exome sequencing trio study.

We describe the cryoelectron microscopy (cryo-EM) structure of mycobacteriophage Douge, which contains 1,105 protein subunits assembled into a complete siphophage and is coated with glycan-binding domains for mycobacterial cell surface interactions.

這項研究有助於了解動物基因體結構的重排與演化適應之間的關聯，並揭示染色體結構穩定性的分子機制。

We demonstrate that RepRanger represents a versatile tool for discovering REPs in bacteria and archaea, providing new insights into their functions and sequence diversity.

Our findings demonstrated that G9 function requires multiple domains, including A16-binding interfaces and conserved motifs not resolved in previous protein structure. These results establish G9 as a central EFC component and underscore its potential as a target for antiviral development.