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 Date : 2021/09/27 No:271 
 
 
 

Recent News

 
 
 
 
New Books
 
 
Period: 2021-09-27 ~ 2021-10-04
 
 
 
 
 
 
 
2021 Future Tech Awards
 
 
The winners of the " Future Tech Awards " have been announced with the enthusiastic participation of all technology leaders.
 
 
 
 
 
Significant Research Achievements of poster show Dr. Yin-Ru Chiang
 
 
Significant Research Achievements of poster show Dr. Yin-Ru Chiang

 
 
Date: 2021/09/27 ~ 2021/10/17
Place: Life Science Library
 
 
 
 
 
 

Training Courses

 
 
 
 
【Design and statistical analysis of clinical trials】series courses. Unit 2:Study design in phase I trials (in Chinese)
 
2021-09-28(Tue)10:00~12:00
Dr.Mey Wang(Academia Sinica Data Science Statistical Cooperation Center)
209 Seminar Room, IBC
 
 
 
 
【Bioinformatics series 】9-1:Dynamics in systems biology(In English)
 
2021-09-29(Wed)10:00~12:00
Dr. Chao-Ping Hsu (Research Fellow, Institute of Chemistry, Academia Sinica)
Online
 
 
 
 
 
 
【Bioinformatics series 】10:RDKit for Chemoinformatics(In Chinese)
 
2021-09-30(Thu)14:00~16:00
Ms.Pei-Ying Chu (Assistant, Research Center for Applied Sciences, Academia Sinica)
Online
 
 
 
 
【Bioinformatics series 】9-2:Dynamics in systems biology(In English)
 
2021-10-06(Wed)10:00~12:00
Dr. Chao-Ping Hsu (Research Fellow, Institute of Chemistry, Academia Sinica)
209 Seminar Room, IBC
 
 
 
 
 
 
【Bioinformatics series 】11:Alternative-splicing detection by NGS(In English)
 
2021-10-07(Thu)14:00~16:00
Dr. Wen-Dar Lin (Associate Research Specialist , Institute of Plant and Microbial Biology, Academia Sinica)
Online
 
 
 
   
 
 
 

Lectures

 
 
 
 
9/28 IMB Seminar
 
 
Topic:IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models
Speaker:Dr. Ming-Shi Chang
Date:2021-9-28 11:00
Place:IMB B1 Auditorium
 
 
 
 
 
 
 
10/5 IBMS Seminar
 
 
Topic:ATP-releasing Pannexin 1 channels mediate sympathetic regulation of cardiovascular physiology
Speaker:Yu-Hsin Chiu, Ph.D.
Date:2021-10-05 11:00-12:00
Place:B1C Lecture Room, IBMS
 
 
 
 
 
 
 
10/13 IMB Seminar
 
 
Topic:A virtual reality system to study predictive neural processing during social interaction
Speaker:Dr. Kuo-Hua Huang
Date:2021-10-13 11:00
Place:IMB B1 Auditorium
 
 
 
 
 
 
 
10/14 IBC Seminar
 
 
Topic:Chemical and Biochemical Tools to Study the Function of Bacterial Biofilm Exopolysaccharides
Speaker:Dr.Myles B. Poulin
Date:2021-10-14 11:00-12:30
Place:IBC R209
 
 
 
 
 
 

Seminars

 
 
 
 
International Conference on Advanced Biomedical Sciences, Taiwan 2021 (ICABS, Taichung 2021)
 
 
 
 
 
 
 
 

Important Research

 
 
 
 
Whole-body clonal mapping identifies giant dominant clones in zebrafish skin epidermis
 
 
Skin expansion during development is predominantly driven by growth of basal epithelial cell (BEC)-derived clonal populations, which often display varied sizes and shapes. However, little is known about the causes of clonal heterogeneity and the maximum size to which a single clone can grow......
 
 
 
 
 
 
 
 
Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies
 
 
Attachment of polyethylene glycol (PEG) to small molecules, nucleotides, peptides, proteins, liposomes and nanoparticles is widely used to improve their stability, solubility and pharmacokinetic properties. Prolonged circulation times enhances patient compliance and quality of life because the frequency of needle injections can be dramatically reduced......
 
 
 
 
 
 
 
 
Pdia4 regulates β-cell pathogenesis in diabetes: molecular mechanism and targeted therapy
 
 
Diabetes has been not curable for the past 2000 years due to loss of β-cell number and function. β-cell preservation is therefore a promising strategy to treat and reverse diabetes. In this publication, we first found that Pdia4 was primarily expressed in β-cells. This expression was up-regulated in β-cells of mice in response to excess nutrients. Ablation of Pdia4 alleviated diabetes as shown by reduced islet destruction, blood glucose and HbA1c, reactive oxygen species (ROS), and increased insulin secretion in diabetic mice. Strikingly, this ablation could fully reverse diabetes......
 
 
 
 
 
 
 
 
 
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