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 Date : 2023/09/25 No:319 

Recent News

New Books
Period: 2023-09-25 ~ 2023-10-02
The Library will be closed for the Mid-Autumn Festival on Septermber 29, 2023. Happy Holidays!
The Library will be closed for the Mid-Autumn Festival on Septermber 29, 2023. 
Happy Holidays!

Significant Research Achievements of poster show Dr. Ya-Hui Chou

Date: 9/25/2023-10/25/2023
Place: Life Science Library, Academia Sinica (Eco Pavilion)
OA Journals and Discounts


Training Courses

【Clinical Trial Lecture-Basic Course】Lesson 1-Basic concepts of clinical trials(In Chinese)(Physical and Video Class)
Dr.Mey Wang
B1 Auditorium, Institute of Statistical Science


9/27 GRC Seminar

Topic:Modulating Hippocampal Neurons and Connections: Implications for Anxiety
Speaker:Professor Cheng Chang Lien (National Yang Ming Chiao Tung University, TAIWAN)
Date:2023-09-27 15:30 - 17:00
Place:Auditorium, Genomics Research Center
9/27 BRCAS Seminar

Topic:The Mitochondrial Interference Hypothesis, A New Hypothesis for An Old Story
Speaker:Dr. Andrea Pozzi (Ludwig-Maximilians-Universität München, Germany)
Date:2023-09-27 15:30 - 16:30
Place:Auditorium, 1st Floor, Interdisciplinary Research Building
10/2 IBMS Seminar

Topic:Neuron-glial interactions in health and disease: from cognition to cancer
Speaker:Dr. Michelle Monje (Stanford Univ.)
Date:2023-10-02 10:00 - 11:00
Place:B1C Auditorium, IBMS
10/2 ABRC Seminar

Topic:What animal self-medication in the wild can teach us about antiparasitic and other phytotherapies for humans and domestic animals?
Speaker:Dr. Michael Alan Huffman (Associate Professor, Wildlife Research Center, Inuyama Campus, Kyoto University, Japan)
Date:2023-10-02 11:00 - 12:00
Place:Auditorium A134, Agricultural Technology Building
10/2 ICOB Seminar

Topic:Gene Regulation by 3D Genome Topology in Single Cells
Speaker:Dr. James Zhe Liu (Group Leader, Janelia Research Campus, Howard Hughes Medical Inistitue, Ashburn, Virginia, USA)
Date:2023-10-02 11:00 - 12:00
Place:1F, Auditorium, Institute of Cellular and Organismic Biology
10/4 GRC Seminar

Topic:From Cells to Systems-- understanding how cells collectively perform systems - level functions in health and disease from a single cell multiomic perspective
Speaker:Kevin Wang, MD, PhD
Date:2023-10-04 10:00 - 12:00
Place:1F Auditorium, Genomics Research Center
10/5 IBMS Seminar

Topic:Precision Oncology: Tumor maintenance, Collateral Lethality and Synthetic Essentiality
Speaker:Prof. Ronald A. DePinho (The Univ. of Texas MD Anderson Cancer Center)
Date:2023-10-05 11:00 - 12:00
Place:B1C Auditorium, IBMS

Important Research

Virulence and ecology of agrobacteria in the context of evolutionary genomics

Agrobacteria are important plant pathogens that impact agriculture, as well as a critical genetic transformation tool for basic research in plant sciences and application in agricultural biotechnology.
Trade-off between local replication and long-distance dissemination during experimental evolution of a satellite RNA

Satellite RNAs (satRNAs) are molecular parasites that depend on their non-homologous helper viruses (HVs) for essential biological functions. While there are multiple molecular and phylogenetic studies on satRNAs, there is no experimental evolution study on how satRNAs may evolve in common infection conditions.
CryoEM Reveals Mechanism Behind Polymyxin-Resistant Infections

In the escalating fight against drug-resistant Gram-negative bacteria, polymyxins are a last resort. Alarming is the rise of polymyxin-resistant infections, a major public health threat.
Autism-related KLHL17 and SYNPO act in concert to control activity-dependent dendritic spine enlargement and the spine apparatus

A research team led by Dr. Yi-Ping Hsueh, Distinguished Research Fellow at the Institute of Molecular Biology, Academia Sinca used high-end optical microscopy and biochemical approaches to demonstrate that KLHL17 and SYNPO, two autism-linked proteins, act in concert to regulate the organization and distribution of the spine apparatus, a specialized endoplasmic reticulum structure at excitatory synapses.
Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein
The Battle between Pathogenic Fungi and Plant Hosts: Fungal Strategies_Part 1

The Pathogenesis-related-1 (PR-1) family proteins are present in all kingdoms of life. During the co-evolutionary arms race, fungal pathogen PR-1 homologs (PR-1-like) evolved to counteract the action of plant PR-1, facilitating colonization.
CIPK15-mediated inhibition of NH4+transport protects Arabidopsis from submergence

Nitrogen is widely recognized as a crucial element for plants due to its role as a fundamental building block for essential macromolecules such as nucleic acids, amino acids, and proteins.
The modulation of pulmonary group 2 innate lymphoid cell function in asthma: from inflammatory mediators to environmental and metabolic factors

A dysregulated type 2 immune response is one of the fundamental causes of allergic asthma. Although Th2 cells are undoubtedly central to the pathogenesis of allergic asthma, the discovery of group 2 innate lymphoid cells (ILC2s) has added another layer of complexity to the etiology of this chronic disease.
Extracellular calcium functions as a molecular glue for transmembrane helices to activate the scramblase Xkr4

The "eat me" signal, phosphatidylserine is exposed on the surface of dying cells by phospholipid scrambling. Previously, we showed that the Xkr family protein Xkr4 is activated by caspase-mediated cleavage and binding of the XRCC4 fragment.
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