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 Date : 2024/05/13 No:335 
 
 
 

Recent News

 
 
 
 
New Books
 
Period: 2024-5-13 ~ 2024-5-20
 
 
 
 
 
 
 
Significant Research Achievements of poster show Dr. Chien-Hsiang Lin

 
Date: 5/13/2024-6/12/2024
 
 
 
 
 
 

Training Courses

 
 
 
Using IPA to integrate genomic data with bioinformatics tools to explore the mechanisms of complex diseases.(In English)(Physical and Video Class)
 
2024-05-17(Fri)13:30~16:00
Ms.Christine Hsiung(Project Supervisor,GGA Corp)
2F Computer classroom, Bldg. D, NBRP
 
 
 
 
EndNote Advanced(In Chinese)(Physical and Video Class)
 
2024-05-23(Thu)10:00~12:00
Lecturer at Shou Ray Information Service Co., Ltd.
208 Seminar Room, IBC
 
 
 
 
 
 
【Bioinformatics series】7:Annotation and enrichment analysis(In Chinese)(Physical and Video Class)
 
2024-05-28(Tue)14:00~16:00
Dr.EN-YU LAI(Institute of Statistical Science, Academia Sinica)
B1 Auditorium, Institute of Statistical Science
 
 
 
   
 
 
 

Lectures

 
 
 
 
5/14 IBC Seminar

 
Topic:Genomics accelerated discovery and biosynthesis of microbial natural products
Speaker:IBC R209
Date:2024-05-14 11:00 - 12:00
Place:Dr. Kou-San Ju (The Ohio State University, USA)
 
 
 
 
 
 
 
5/14 IMB Seminar

 
Topic:Revisiting bacteriophage-host interaction at nanometer scale via CryoEM/CryoET
Speaker:Dr. Meng-Chiao Joseph Ho (Associate Research Fellow, Institute of Biological Chemistry Academia Sinica)
Date:2024-05-14 11:00 - 12:00
Place:1F Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
5/15 IMB Seminar

 
Topic:Discovery of treasure non-coding RNAs and the functional features
Speaker:Dr. Hazuki Takahashi (Permanent Research Scientist, RIKEN Center for Integrative Medical Sciences, Laboratory for Transcriptome Technology, Yokohama, Japan)
Date:2024-05-15 14:00 - 15:30
Place:B1 Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
5/16 IBC Seminar

 
Topic:Physics as a cellular signaling to perform biological functions
Speaker:Dr. Keng-hui Lin (IoP)
Date:2024-05-16 11:00 - 12:00
Place:IBC R209
 
 
 
 
 
 
 
5/16 BRCAS Seminar

 
Topic:An Emerging Photosymbiotic Marine Model Animal: The Acoele Symsagittifera roscoffensis and Its Green Microalgae Photosymbiont
Speaker:Dr. Xavier Bailly (Marine Institute of Roscoff in Brittany, France)
Date:2024-05-16 15:00 - 16:30
Place:Auditorium, 1st Floor, Interdisciplinary Research Building
 
 
 
 
 
 
 
5/17 NPAS-IBMS Joint Seminar

 
Topic:Accelerating Biomedical Research with NVIDIA Technology
Speaker:Dr. Chi-Cheng Fu (Senior Developer Relations Manager, NVIDIA)
Date:2024-05-17 11:00 - 12:00
Place:B1C Auditorium, IBMS
 
 
 
 
 
 
 
5/20 IMB Seminar

 
Topic:Behavioral Exhibition of Bacteria
Speaker:Dr. Daisuke NakaneAssociate (Professor Department of Engineering Science, University of Electro-Communications, Japan)
Date:2024-05-20 11:00 - 12:00
Place:1F Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
5/20 IBMS Seminar

 
Topic:Metabolic Insights and Synergistic Cell Therapy for Cardiac Regeneration
Speaker:Dr. Hsieh, Patrick Ching-Ho (Distinguished Research Fellow)
Date:2024-05-20 11:00 - 12:00
Place:B1C Auditorium, IBMS
 
 
 
 
 
 
 
5/20 ABRC Seminar

 
Topic:Overview of Screening Platforms for Natural Product Drug Discovery - Learning from the Small Molecules
Speaker:Prof. Cherry Wainwright (Professor Emeritus, School of Pharmacy & Life Sciences, Robert Gordon University, Scotland, UK)
Date:2024-05-20 11:00 - 12:00
Place:Auditorium A134, Agricultural Technology Building
 
 
 
 
 
 
 
5/21 IMB Seminar

 
Topic:Unveiling the Eukaryotic Transcriptional Mediator Complex: Structure and Regulatory Mechanisms
Speaker:Dr. Kuang-Lei Tsai (Tenure Track Assistant Professor, Dept. of Biochemistry and Molecular Biology, UT Health Science McGovern Medical School, Houston TX, USA)
Date:2024-05-21 11:00 - 12:00
Place:B1 Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
5/22 IPMB Seminar

 
Topic:Adventures with thermophilic hot-spring cyanobacteria and heat-tolerant marine cyanobacteria in Taiwan
Speaker:Dr. Hsiu‐An Chu (Associate Research Fellow, Institute of Plant and Microbial Biology, Academia Sinica)
Date:2024-05-22 11:00 - 12:00
Place:Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica
 
 
 
 
 
 
 
5/23 NPAS Seminar

 
Topic:Attention and Reward Signals in Noncholinergic Basal Forebrain Neurons
Speaker:Prof. Shih-Chieh Lin (Inst. of Neuroscience, Nat'l Yang Ming Chiao Tung Univ.)
Date:2024-05-23 11:00 - 12:00
Place:1F Auditorium (B106), IST
 
 
 
 
 
 
 
5/24 IMB Seminar

 
Topic:Metabolic cross-feeding networks in gut and ocean communities
Speaker:Dr. Uwe Sauer (Director and Professor, Institute of Molecular Systems Biology, ETH, Zurich, Switzerland)
Date:2024-05-24 10:00 - 11:00
Place:B1 Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
5/24 IPMB Seminar

 
Topic:Cell-type specific expansin overexpression and proton pump activation questions the acid growth theory in Arabidopsis roots
Speaker:Dr. Samalova Marketa (Associate Professor, Department of Experimental Biology, Masaryk University, Brno, Czech Republic)
Date:2024-05-24 15:00 - 16:00
Place:Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica
 
 
 
 
 
 

Important Research

 
 
 
 
IRON MAN, a jack of all trades

 
A small family of non-secreted peptides, originally identified at IPMB as critical communicators of the plant’s iron status, was recently associated with a suite of novel and unexpected functions.
 
 
 
 
 
 
 
 
IPMB proteomics research in the spotlight

 
Recent research on pH-dependent changes in protein phosphorylation patterns is featured on the cover of a special issue of the journal Molecular & Cellular Proteomics on ‘Plant Proteomics’.
 
 
 
 
 
 
 
 
Structural basis and synergism of ATP and Na+ activation in bacterial K+ uptake system KtrAB

 
The K+ uptake system KtrAB is essential for bacterial survival in low K+ environments. The activity of KtrAB is regulated by nucleotides and Na+. Previous studies proposed a putative gating mechanism of KtrB regulated by KtrA upon binding to ATP or ADP.
 
 
 
 
 
 
 
 
Biochemical characterization of the meiosis-essential yet evolutionarily divergent topoisomerase VIB-like protein MTOPVIB from Arabidopsis thaliana

 
Formation of programmed DNA double-strand breaks is essential for initiating meiotic recombination.
 
 
 
 
 
 
 
 
Hfq-Antisense RNA I Binding Regulates RNase E-Dependent RNA Stability and ColE1 Plasmid Copy Number

 
The mechanisms and consequences of gene regulation by Hfq on trans-encoded small RNAs (sRNAs) have been well studied and documented. Recent employment of Genomic SELEX to search for Hfq-binding motifs has indicated that Hfq might frequently regulate gene expression controlled by cis-antisense RNAs.
 
 
 
 
 
 
 
 
A keratinocyte-adipocyte signaling loop is reprogrammed by loss of BTG3 to augment skin carcinogenesis

 
Obesity is endemic to many developed countries. Overweight or obesity is associated with an increased risk of developing cancer.
 
 
 
 
 
 
 
 
Active loading of cyanine 5.5 derivatives into liposomes for deep self-quenching and their applications in deep tissue imaging

 
Visualizing liposome release profiles in small animals is important for evaluating the pharmacokinetic influence of vesicles.
 
 
 
 
 
 
 
 
Non-Heme Iron Enzymes Catalyze Heterobicyclic and Spirocyclic Isoquinolone Core Formation in Piperazine Alkaloid Biosynthesis

 
We report the discovery and biosynthesis of new piperazine alkaloids-arizonamides, and their derived compounds-arizolidines, featuring heterobicyclic and spirocyclic isoquinolone skeletons, respectively.
 
 
 
 
 
 
 
 
 
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