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Period: 2024-10-21 ~ 2024-10-28 |
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| | | | | | 【Clinical Trial Lecture-Basic Course】Lesson 2—Design and requirements of preclinical study to support clinical trial in new drug development (In Chinese)(Physical and Video Class) | | | 2024-10-23（Wed）10:00~12:00
Dr.Chia-Hsin Yeh (CDE,Taiwan)
Research Building of Environmental Changes, AS, 6005 Room
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| | | | | Combining QIAGEN IPA and BIOVIA Discovery Studio for Multi target Compound Analysis(In Chinese)(Physical and Video Class) | | | 2024-10-25（Fri）09:30~11:30
Mr.Gene Chen(GGA Corp)
209 Seminar Room, IBC
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| | | | | | | 【Clinical Trial Lecture-Basic Course】Lesson 3—Key clinical considerations of clinical trials(In Chinese)(Physical and Video Class) | | | 2024-10-29（Tue）10:00~12:00
Dr.CHIAO-YING HSU(CDE,Taiwan)
Research Building of Environmental Changes, AS, 6005 Room
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Topic：Deciphering protein modifications and complex structures: The role of advanced analytical technologies in biomedical research
Speaker：Dr. Yeou-Guang Tsay (Nat'l Yang Ming Chiao Tung Univ.)
Date：2024-10-22 11:00 - 12:00
Place：B1B Lecture Room, IBMS |
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Topic：Writing a fundable proposal: reading reviewer’s mind (Part II) Validating the Principles: dissecting a funded proposal
Speaker：Dr. Tien-Hsien Chang (Research Fellow, GRC)
Date：2024-10-23 10:00 - 12:00
Place：B1C Lecture Room, IBMS |
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Topic：Ground-Breaking Discoveries: Progress in Understanding Soil-emerging Xylaria Species
Speaker：Dr. Yu-Ming Ju (Research Fellow, Institute of Plant and Microbial Biology, Academia Sinica)
Date：2024-10-25 11:00 - 13:00
Place：Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica |
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Topic：Time me by the moon : The evolution and function of lunar timing systems
Speaker：Dr. Kristin Tessmar-Raible (Professor, Max Perutz Labs, Centre for Molecular Biology, University of Vienna, Austria)
Date：2024-10-28 11:00 - 12:00
Place：1F, Auditorium, Institute of Cellular and Organismic Biology |
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Topic：Discovery of glycoconjugate receptors for bacterial toxins
Speaker：Dr. Jennifer J. Kohler (University of Texas Southwestern Medical Center, USA)
Date：2024-10-28 11:00 - 12:00
Place：IBC R209 |
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Topic：Role of BTG3 in Epidermal Health and Disease
Speaker：Dr. Shieh, Sheau-Yann (Research Fellow)
Date：2024-10-28 11:00 - 12:00
Place：B1C Auditorium, IBMS |
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Topic：Idioblasts in Plants: Co-option and Neofunctionalization of Stomatal Transcription Factors for Defense Against Herbivores in Brassicales
Speaker：Dr. Makoto Shirakawa (Assistant Professor, Nara Institute of Science and Technology Japan)
Date：2024-10-28 14:00 - 16:00
Place：Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica |
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Topic：Fungal-bacterial Interactions Alter Microbial Fitness and the Evolution of Antibiotic Resistance
Speaker：Dr. Yu-Ying Phoebe Hsieh (Post-doc Fellow, Fred Hutchinson Cancer Center, USA)
Date：2024-10-30 10:00 - 12:00
Place：Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica |
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Topic：A Structural Perspective of the Pathological Threshold in Huntington’s Disease
Speaker：Dr. Pau Bernadó (Centre de Biologie Structurale (CBS). France)
Date：2024-10-30 11:00 - 12:00
Place：IBC R209 |
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Topic：Unraveling the Mechanisms of Site Selectivity in Fucosylation by Fucosyltransferases
Speaker：Professor Tzu-Hsiung Yang (National Tsing Hua University)
Date：2024-10-30 15:30 - 17:00
Place：1F Auditorium, Genomics Research Center |
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Topic：Tau-oligomer-targeting therapy for Alzheimer’s disease—from target discovery to human clinical trial
Speaker：Dr. Hwan-Ching Tai (Xiamen Univ.)
Date：2024-10-31 14:00 - 15:00
Place：B1C Auditorium, IBMS |
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Nucleotide-binding domain and leucine-rich repeat (NLR) proteins function as immune receptors and play a crucial role in the immune systems of both animals and plants. In solanaceous plants, some sensor NLR immune receptors activate their helper NLR immune receptors (NRC) to form resistosome complexes after recognizing pathogens, thereby initiating immune responses. |
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Vinca alkaloids, a class of tubulin-binding agent, are widely used in treating cancer, yet the emerging resistance compromises their efficacy. Hepatoma up-regulated protein (HURP), a microtubule-associated protein displaying heightened expression across various cancer types, reduces cancer cells’ sensitivity to vinca-alkaloid drugs upon overexpression. |
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Polarization is crucial for the proper functioning of epithelial cells. Early polarization features include the trafficking and enrichment of polarity molecules to form the apical membrane (AM) or cell-cell junctions, as well as the apical positioning of the centrosome. However, the dependencies among polarity molecules, AM formation, and centrosome positioning remain poorly understood. |
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Deuterostomes are one major group of bilaterians composed by hemichordates and echinoderms (collectively called Ambulacraria) and chordates. Comparative studies between these groups can provide valuable insights into the nature of the last common ancestor (LCA) of deuterostomes and that of bilaterians. |
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cFLIP, a master anti-apoptotic regulator, targets the FADD-induced DED complexes of procaspase-8 in death receptor and ripoptosome signaling pathways. |
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