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 Date : 2024/12/02 No:349 
 
 
 

Recent News

 
 
 
 
New Books
 
Period: 2024-12-2 ~ 2024-12-9
 
 
 
 
 
 

Training Courses

 
 
 
【Clinical Trial Lecture-Basic Course】Lesson 6—Study design of Phase III clinical trialstrials(In Chinese)(Physical and Video Class)
 
2024-12-10(Tue)10:00~12:00
Dr. Mey Wang
Research Building of Environmental Changes, AS, 6005 Room
 
 
 
   
 
 
 

Lectures

 
 
 
 
12/3 IMB Seminar

 
Topic:Reprogramming of host protein synthesis and metabolism in poxvirus infection
Speaker:Dr. Zhilong Yang (Associate Professor Dept. of Veterinary Pathobiology Texas A&M University, USA)
Date:2024-12-03 11:00 - 12:00
Place:1F Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
12/9 IPMB Seminar

 
Topic: Plant polygalacturonases: (try) making sense out of diversity/ Contribution of pectin remodelling in the control of plant development/ Role of brassinosteroids in the control of...
Speaker:Prof. Jérôme Pelloux (University of Picardie Jules Verne, Amiens, France)/Assoc. Prof. Valérie Lefebvre (University of Picardie Jules Verne, Amiens, France)/Dr. François Jobert (University of Picardie Jules Verne, Amiens, France)
Date:2024-12-09 14:00 - 17:00
Place:Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica
 
 
 
 
 
 
 
12/10 IMB Seminar

 
Topic:Metabolism, Cellular Decisions and the Language That Unites Them
Speaker:Dr. Jared Rutter (Distinguished Professor, University of Utah School of Medicine, USA)
Date:2024-12-10 11:00 - 12:00
Place:B1 Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
12/10 IBC Seminar

 
Topic:Glycogen debranching enzyme and starch applications
Speaker:Dr. Kuakarun Krusong (Chulalongkorn University, Thailand)
Date:2024-12-10 11:00 - 12:00
Place:IBC R209
 
 
 
 
 
 
 
12/12 IBC Seminar

 
Topic:New Drug Discovery against Pulmonary Tuberculosis
Speaker:Dr. V. Samuel Raj (SRM University, India)
Date:2024-12-12 11:00 - 12:00
Place:IBC R209
 
 
 
 
 
 

Important Research

 
 
 
 
A genomic perspective on prokaryotic taxonomy: Defining genera through gene content differentiation

 
The core of taxonomy lies in grouping and naming organisms, establishing a foundation for biological research and scientific communication. With advancements in genomics, genome sequence analysis has become an essential tool for classifying prokaryotes at the level of species.
 
 
 
 
 
 
 
 
Plausible, robust biological oscillations through allelic buffering

 
We usually think that biological oscillators emerge from feedback interaction between two molecules just like two people dancing.
 
 
 
 
 
 
 
 
Protein moonlighting by a target gene dominates phenotypic divergence of the Sef1 transcriptional regulatory network in yeasts

 
Transcriptional rewiring generates phenotypic novelty, acting as an important mechanism contributing to evolutionary development, speciation, and adaptation in all organisms.
 
 
 
 
 
 
 
 
α-GalCer sp2-iminoglycolipid analogs as CD1d-dependent iNKT modulators: Evaluation of their immunotherapeutic potential in murine models of asthma and autoimmune hepatitis

 
Invariant natural killer T (iNKT) cells are a subset of innate T cells displaying powerful immunomodulatory functions.
 
 
 
 
 
 
 
 
Emergence of a brainstem somatosensory tonotopic map for substrate vibration

 
Perceiving substrate-borne vibrations is a fundamental component of tactile perception. How location (somatotopy) and frequency tuning (tonotopy) of vibrations are integratively processed is poorly understood.
 
 
 
 
 
 
 
 
Emergence and increased epidemic potential of dengue variants with the NS5V357E mutation after consecutive years of transmission

 
Arboviruses can intensify epidemics by acquiring single nucleotide variants, leading to clade replacement and severe outbreaks.
 
 
 
 
 
 
 
 
The role of PM2.5 exposure in lung cancer: mechanisms, genetic factors, and clinical implications

 
Lung cancer is one of the most critical global health threats, as the second most common cancer and leading cause of cancer deaths globally.
 
 
 
 
 
 
 
 
Galectins and Host-Pathogen Interactions: The roles in viral infections

 
Galectins, a family of carbohydrate-binding proteins, play crucial roles in the host-virus interaction landscape.
 
 
 
 
 
 
 
 
Clostridium innocuum, an opportunistic gut pathogen, inactivates host gut progesterone and arrests ovarian follicular development

 
Levels of progesterone, an endogenous female hormone, increase after ovulation; progesterone is crucial in the luteal phase to maintain successful pregnancy and prevent early miscarriage.
 
 
 
 
 
 
 
 
Population genomics insights into hot spring cyanobacteria: A Taiwanese perspective

 
Cyanobacteria are diverse phototrophic microbes with ecological importance and potential for biotechnology applications. Among them, thermophilic species from hot springs have garnered particular attention for their ability to produce thermostable enzymes and proteins with promising industrial uses.
 
 
 
 
 
 
 
 
The QS regulator AphBvp promotes expression of the AHPND PirAvp and PirBvp toxins and may enhance virulence under acidic conditions

 
Shrimp acute hepatopancreatic necrosis disease (AHPND) is one of the most devastating diseases to impact the global shrimp farming industry, with a mortality rate of 70 %-100 %.
 
 
 
 
 
 
 
 
 
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