Period:2025-04-28~ 2025-05-05

4/21-Turnitin training course for student (In Chinese)
4/25-EndNote 21 Essentials (Windows & Mac)(In Chinese)

Topic：Exposing Pathogen Variation: Engineering Plant Immunity and Investigating Spatial Defense
Speaker：Dr. Gitta Coaker (Professor, Department of Plant Pathology, University of California, Davis, USA)
Date：2025-04-29 11:00 - 13:00
Place：Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica

Topic：Mechanistic insights of immune modulation in poly I:C induced heart regeneration in medaka
Speaker：Kaushik Chowdhury (TIGP-MM Student)
Date：2025-04-30 15:00 - 16:00
Place：B1B Lecture Room, IBMS

Topic：CRL3(BPMs)-mediated auxin signaling in Arabidopsis seedling development
Speaker：Dr. Yueh-Ju Hou (Assistant Professor, Department of Life Sciences, National University of Kaohsiung, Taiwan )
Date：2025-05-02 11:00 - 13:00
Place：Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica

Topic：NPAS Mini-symposium: Modeling human neural development and neurodegenerative diseases by organoid approach
Speaker：Please visit the website for more information
Date：2025-05-07 09:00 - 12:20
Place：1F Auditorium (B106), IST

Topic：Unraveling Stem Cell Dynamics in Skin Regeneration and Aging
Speaker：Dr. Aiko Sada (Professor, Medical Institute of Bioregulation, Kyushu University, Japan) Date：2025-05-05 11:00 - 12:00
Place：1F, Auditorium, Institute of Cellular and Organismic Biology

Topic：Effective transcriptome targeting with Cas13d
Speaker：Dr. Nithila Joseph (Postdoctoral Research Fellow, Wellcome Sanger Institute, Cambridge, UK)
Date：2025-05-06 11:00 - 12:00
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：NPAS Seminars
Speaker：Please visit the website for more information
Date：2025-05-05 10:00 - 12:00
Place：1F Auditorium (B106), IST

Topic：Vesicle Trafficking and Plant Behavior: What we've Discovered?
Speaker：Dr. Wei Siao (Assistant Professor, Institute of Plant Biology, National Taiwan University, Taiwan)
Date：2025-05-07 11:00 - 13:00
Place：Auditorium A134, Agricultural Technology Building, Institute of Plant and Microbial Biology, Academia Sinica

Topic：The NALCN Sodium Leak Channel in Health and Disease
Speaker：Dr. Arnaud Monteil (Mahidol Univ.)
Date：2025-05-09 14:00 - 15:00
Place：B1B Lecture Room, IBMS

Topic：Ecology, conservation and restoration of corals in Taiwan
Speaker：Dr. Tung-Yung Fan (Research Fellow, Department of Planning and Research, National Museum of Marine Biology and Aquarium, Taiwan)
Date：2025-05-12 11:00 - 12:00
Place：1F, Auditorium, ICOB

Speaker: Academician Chung-Pei Ma (Judy Chandler Webb Chair Professor in Physical Sciences, University of California, Berkeley; Adjunct Research Fellow, Institute of Astronomy and Astrophysics, Academia Sinica)
Moderator: Academician Mei-Yin Chou, Vice President, Academia Sinica
Date: 7:00-8:30 pm, Tuesday, May 13, 2025
Venue: Conference Room 1, 2F, Academic Activity Center, Academia Sinica

Topic：Protein Science and Engineering in the New Era
Date：2025-04-29 09:00 ~ 2025-04-30 17:30
Location：IBC 103 Auditorium

Exosomes are responsible for intercellular communication and are widely valued in medicine and bioindustry. The team led by Dr. Ruey-Hwa Chen, a distinguished research fellow at the Institute of Biological Chemistry, has recently made a major breakthrough in the mechanism of exosome biogenesis. They discovered that cells contain two types of multivesicular bodies (MVBs), MVBs with PTPN23 are directed to lysosomes for degradation, while MVBs with ALIX are delivered to the cell membrane via actin cytoskeleton regulation for exosome secretion. The released exosomes are loaded with tumor-promoting proteins to enhance metastasis and tumor immune evasion. This study has broad impacts on boosting exosome production in bioindustry and devising cancer therapeutic strategy.

“Sng” or “Sng-pain” is a Taiwanese term that denotes an acid-like discomfort, one of the most common complaints in pain clinics. Although the cost of medical care spent on sng or sng-pain is the highest among all diseases all over the world, current analgesics are not very effective for many types of intractable sng or sng-pain (e.g., fibromyalgia). To solve the unmet medical needs of intractable sng-pain, the research team have found sng and pain are two different somatosensory functions, with proprioceptors are the sngceptors to sense tissue acidosis and to trigger the acid-induced priming and “pain” chronicity in moused models of fibromyalgia.

Agroinfiltration is a widely used technique in plant gene research, where bacteria are used to temporarily introduce foreign genes into plant leaves, enabling rapid functional analysis. Traditionally, Agrobacterium tumefaciens has been the bacterium of choice. Through a systematic screen, our recent study shows that a strain of Rhizobium rhizogenes, a relative of A. tumefaciens, delivers genes even more effectively.

To ascertain such linguistic mystery, we conducted a survey of 10 languages from different language families and found that 3 of them use words related to the “sour” taste to depict musculoskeletal discomforts.

Restriction factors serve as innate host defenses against viruses and act as critical barriers to cross-species transmission. In response, viruses have evolved accessory proteins to counteract restriction factors, enabling evasion of innate immune responses.

Human inflammation-related CC chemokine ligand 5 (hCCL5) has significant self-assembly property under physiological conditions

Agrobacterium tumefaciens is a plant pathogen causing crown gall disease, relies on type IV secretion system (T4SS) for pathogenesis and type VI secretion system (T6SS) for niche competition. The research team has identified new players in modulating virulence and interbacterial competition through distinct regulatory mechanisms. These findings provide new insights for future applications in genetic transformation technology and disease control.