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 Date : 2025/10/13 No:370 
 
 
 

Recent News

 
 
 
 
New Books
 
Period: 2025-10-13~ 2025-10-20
 
 
 
 
 
Forwarded Announcement
 
 
Forwarded Announcement
 
Turnitin will have a scheduled system maintenance October 25 23:00 – October 26 05:00 CST. Due to the maintenance, Turnitin may have disruptions in service between those times
 
 
 
 
 
 
 
Welcome to join the BioRender Class
 
Topic:Create Graphical Abstracts Like a Pro
Date:Oct 16, 2025 at 9:00 am EDT
 
 
 
 
 
 
 
Henry Stewart Talks October recently added
 
 
 
 
 
 
 
 
Academia Sinica’s Internally Developed Quantum Computing Test Space Opens for Applications
 
The Research Center for Critical Issues (RCCI) at Academia Sinica announced that the Quantum Computing Test Space (QC-Test) has entered its pilot operation on September 10. This platform currently features two internally developed 5-qubit superconducting quantum processing units (QPUs), now open for research teams and collaborative partners in quantum algorithm testing, research and development to apply for on-line access. The launch of QC-Test provides Taiwan’s quantum computing research community with a practical infrastructure for both innovation and validation.
 
 
 
 
 
 

Training Courses

 
 
 
【Bioinformatics series】Single cell analysis (In Chinese)(Physical and Video Class)
 
2025-10-14(Tue)14:00~16:00
Dr.Yu, Chen-Hsin(Assistant Research Specialist,IMB)
Research Building of Environmental Changes, AS, 6005 Room
 
 
 
 
AI-Powered WoS & JCR: Easily Unlock SCIE/SSCI Scientific Treasures and Top Journal Rankings! (In Chinese)(Physical and Video Class)
 
2025-10-20(Mon)14:30~16:30
Mr. Max Lin(Shou Ray Information Service Co., Ltd.)
B1A Conference Room, IBMS
 
 
 
 
 
 
【Clinical Trial series】Lesson 3—Key clinical considerations of clinical trials(In Chinese)(Physical and Video Class)
 
2025-10-21(Tue)10:00~12:00
Dr.Chang(CDE)
Research Building of Environmental Changes, AS, 6005 Room
 
 
 
 
【LSL eResources series】Turnitin training course for student (In Chinese)(Video Class)
 
2025-10-27(Mon)09:30~10:30
Ms. Weichi Dai (iGroup Taiwan)
Online
 
 
 
 
 
 
【LSL eResources series】Turnitin training course for student (In English)(Video Class)
 
2026-10-07(Wed)14:00~15:00
Ms. Weichi Dai (iGroup Taiwan)
208 Seminar Room, IBC
 
 
 
 
【Clinical Trial series】Lesson 4—Study design of Phase I clinical trials(In Chinese)(Physical and Video Class)
 
2025-10-28(Tue)10:00~12:00
Dr.Mey Wang
Research Building of Environmental Changes, AS, 6005 Room
 
 
 
 
 
 
One-Stop AI-Powered New Drug Development Platform - Generative Therapeutics Design (In Chinese)(Physical Class)
 
2025-10-28(Tue)14:00~16:00
Mr.Gene Chen(Manager, MSDIC)
B1B Auditorium, IBMS
 
 
 
   
 
 
 

Video Service

 
 
 
 
Welcome to browse the video service of LSL courses
 
9/30-Alternative-splicing detection by NGS(In English)
9/25-Using TAIR for Plant Research: Practical Tools for Arabidopsis and Crops(In Chinese)
9/18-GWAS Fundamentals and Advanced Applications: Bridging Genes and Diseases(In Chinese)
 
 
 
 
 
 

Feature Story

 
 
 
 
Academia Sinica Builds First Dual Carbon Fixation System in Plants, Published in Science
 
The carbon absorbed by plants through photosynthesis accounts for the vast majority of carbon uptake on Earth. However, the efficiency of this process still leaves much room for improvement. Enhancing carbon fixation efficiency in plants and promoting their growth is a major focus of the global scientific community.
 
 
 
 
 
 

Lectures

 
 
 
 
10/15 GRC Seminar
 
Topic:Toward brain injury therapy: from epigenome, mitochondrial homeostasis to drug development
Speaker:Professor and Dean Linyi Chen (National Tsing-Hua University)
Date:2025-10-15 10:30 - 11:50
Place:1F Auditorium, Genomics Research Center
 
 
 
 
 
 
 
10/16 IPMB Seminar
 
Topic:Catch a tiger by the TALE: Convergently evolved resistance to Xanthomonas in rice and tomato
Speaker:Dr. Adam J. Bogdanove (Plant Pathology and Plant-Microbe Biology, Cornell University, USA)
Date:2025-10-16 11:00 - 13:00
Place:Auditorium A134, Agricultural Technology Building, Academia Sinica
 
 
 
 
 
 
 
10/16 IBMS Seminar
 
Topic:Biological pacemaker enables device-free rhythm restoration and syncope rescue
Speaker:Dr. Liu Chih-Min (Taipei Veterans General Hospital)
Date:2025-10-16 16:00 - 17:15
Place:B1B Lecture Room, IBMS
 
 
 
 
 
 
 
10/20 ICOB Seminar
 
Topic:Regeneration in Planarians: Why Some Species Can and Others Cannot?
Speaker:Dr. Jochen RINK (Department of Tissue Dynamics and Regeneration, Max Planck Institute for Biophysical Chemistry, Germany)
Date:2025-10-20 11:00 - 12:00
Place:Auditorium, ICOB
 
 
 
 
 
 
 
10/20 IPMB Seminar
 
Topic:Illuminating protein clusters in plant transcription and epigenetics
Speaker:Dr. Geng-Jen Jang (Postdoctoral Researcher, Max Planck Institute of Immunobiology & Epigenetics, Germany)
Date:2025-10-20 10:00 - 12:00
Place:Auditorium A134, Agricultural Technology Building, Academia Sinica
 
 
 
 
 
 
 
10/20 IBMS Seminar
 
Topic:Dissecting the nuance of virus-specific T cells in human health and disease
Speaker:B1B Lecture Room, IBMS
Date:2025-10-20 11:00 - 12:15
Place:Dr. Yang Cheng (Assistant Research Fellow)
 
 
 
 
 
 
 
10/21 NPAS Seminar
 
Topic:Please see the content for more information
Speaker:Please see the content for more information
Date:2025-10-21 10:00 - 12:00
Place:1F Auditorium (B106), IST
 
 
 
 
 
 
 
10/22 GRC Seminar
 
Topic:The All Encompassing Importance of Innate Immune Receptors
Speaker:Academician Jenny Pan-Yun Ting (University of North Carolina, USA)
Date:2025-10-22 10:30 - 11:50
Place:1F Auditorium, Genomics Research Center
 
 
 
 
 
 
 
10/27 ICOB & EMBO sponsored Seminar
 
Topic:How an Electrophysiological Signal is Integrated into Scaling the Fins during Regeneration and Development
Speaker:Dr. Christopher Antos (ShanghaiTech University, China)
Date2025-10-27 11:00 - 12:30:
Place:Auditorium, Institute of Cellular and Organismic Biology
 
 
 
 
 
 
 
10/27 IBMS Seminar
 
Topic:Optical control of neurotransmission: from molecular design to in vivo manipulation
Speaker:Dr. Wan-Chen Lin (Assistant Research Fellow)
Date:2025-10-27 11:00 - 12:15
Place:B1B Lecture Room, IBMS
 
 
 
 
 
 

Seminars

 
 
 
 
The 17th SFY Memorial Lecture
 
Date:2025-10-14 01:30 - 17:00
Place:International Conference Hall, Humanity and Social Science Building, Academia Sinica
 
 
 
 
 
 

Important Research

 
 
 
 
Dual-cycle CO2 fixation enhances growth and lipid synthesis in Arabidopsis thaliana
 
In this work, we introduced in Arabidopsis thaliana a new-to-nature CO2 fixing cycle, malyl-CoA-glycerate (McG) cycle, which together with the CBB cycle forms a dual-cycle CO2 fixation system.
 
 
 
 
 
 
 
Bipartite Genetically Encoded Biosensors to Sense Calcium Ion Dynamics at Membrane-Membrane Contact Sites
 
Self-complementing bipartite fluorescent proteins (FPs) are useful tools for the detection of protein-protein proximity and for localizing fluorophores to membrane-membrane contact sites.
 
 
 
 
 
 
 
AAV-mediated delivery of a broadly neutralizing anti-flavivirus antibody protects against dengue and Zika viruses in a mouse model
 
Flaviviruses contain many important human pathogens such as dengue virus (DENV) and Zika virus (ZIKV).Our results demonstrate the effectiveness of rAAV in delivering bnAb 752-2C8 for long-term protection against multiple flaviviruses, providing a potential strategy to control flavivirus infections and possibly other viral diseases.
 
 
 
 
 
 
 
Paradoxical association between steatotic liver disease and favorable hepatic outcomes in HCV patients with SVRs
 
A 15-year prospective study of CHC patients with SVRs was conducted.
 
 
 
 
 
 
 
Intensive reassortment and frequent intercontinental transmission revealed by long-term genetic analysis of H10 avian influenza viruses in Taiwan
 
This study provides a comprehensive overview of the evolutionary dynamics of H10 avian influenza viruses isolated from wild birds in Taiwan, emphasizing the complexity of intercontinental gene flow and viral reassortment.
 
 
 
 
 
 
 
Functional sequence variants of intergenic long non-coding RNA on Chromosome 17q21 are associated with asthma
 
The genetic and molecular basis of asthma remains unclear and its gene-environment interaction is still enigmatic. In the present study, we aimed to identify asthma-causing genetic variants and their interactions with the environment.
 
 
 
 
 
 
 
APP SUMOylation prevents BACE1 cleavage of APP and increases BACE1 degradation to promote the nonamyloidogenic pathway
 
Amyloid precursor protein (APP) plays a key role in the pathogenesis of Alzheimer’s disease (AD).
 
 
 
 
 
 
 
Serotonin 2A receptor attenuates psoriatic inflammation by suppressing IL-23 secretion in monocyte-derived Langerhans cells
 
Our data demonstrate that serotonin modulates HTR2A, attenuating psoriatic inflammation by suppressing IL-23 secretion via inhibiting the non-canonical NFκB pathway in moLCs.
 
 
 
 
 
 
 
Cardiac enrichment of mutant calmodulin protein in a murine model of a human calmodulinopathy
 
Our results support what we believe to be a novel mechanism by which a mutation in a single Calm gene can give rise to a severe phenotype.
 
 
 
 
 
 
 
Antitumor efficacy achieved by targeting PEGylated nanomedicines to netrin-1 in the extracellular matrix or EphA2 on the cancer cell membrane
 
Our results indicate that targeting the extracellular matrix can increase the antitumor activity of some nanomedicines, but that careful selection of compatible nanomedicines is necessary.
 
 
 
 
 
 
 
Nuclear paxillin functions as a molecular switch for alternative splicing in neurons during a critical period of brain development
 
During a critical period of postnatal brain development, neural circuits undergo significant refinement coincident with widespread alternative splicing of hundreds of genes, which undergo altered splice site selection for the generation of isoforms essential for synaptic plasticity.
 
 
 
 
 
 
 
Dual-cycle CO2 fixation enhances growth and lipid synthesis in Arabidopsis thaliana
 
To solve this inefficiency, we introduced a synthetic carbon-fixing cycle, named McG cycle, into plants with native Calvin-Benson-Bassham cycle (CBB), creating an unprecedented “dual-cycle carbon fixation” system.
 
 
 
 
 
 
 
Why Do Birds Build Nest Walls?
 
This study provides the first comprehensive evidence linking egg mass to the evolution of nest architecture. Our findings demonstrate how biological trait evolution can emerge from a simple physical mechanism, resolving one compelling puzzle in bird behavior.
 
 
 
 
 
 
 
Molecular Puppeteering: Roles of Ustilago maydis Effectors.
 
Integrating structural and functional approaches will be essential to decipher effector mechanisms and the molecular arms race between smut fungi and their hosts, ultimately informing strategies for durable crop resistance.
 
 
 
 
 
 
 
Analysing protein complexes in plant science: insights and limitation with AlphaFold 3
 
This review presents an overview of AF3’s advancements, using examples in plant and fungal research, and comparisons with existing tools.
 
 
 
 
 
 
 
Water as a Compass: Hydrostimulation-­Triggered Aerial Root Growth in Phalaenopsis aphrodite
 
Our findings demonstrate that hydrotropism, rather than phototropism or gravitropism, guides aerial root growth in P. aphrodite. This hydrotropic response may represent a key adaptation that enables epiphytic orchids to effectively acquire water in the forest canopy.
 
 
 
 
 
 
 
 
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