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 Date : 2025/11/10 No:372 
 
 
 

Recent News

 
 
 
 
New Books
 
Period: 2025-11-10~ 2025-11-17
 
 
 
 
 
 
 
JoVE & IPMB Tea & Share Event
 
A friendly sharing session co-hosted by JoVE and the Life Science Library. Learn how JoVE videos can support your research and inspire new ideas. Welcome to join us!
Date:11/19 Location:R106, IPMB
 
 
 
 
 
 
 
Welcome to register for the online lecture on November 12, 2025.
 
Date:November 12, 2025 · 11:30 a.m.
 
 
 
 
 
 
 
Academia Sinica Lecture of 2025
 
Topic:Black Holes: Where Disciplines Cross
Speaker:Dr. Peter Galison
Date:14:30-16:30, November 17, 2025 (Monday)
Place:International Conference Hall (3F), Humanities and Social Sciences Building (HSSB), Academia Sinica
Online Registration:https://forms.gle/82GDTH54av2hgi919
 
 
 
 
 
 
 
Taiwan Bridges Series in Academia Sinicare
 
Topic:The end of disease? – The extraordinary developments in biomedicine and the implications for humanity
Speaker:Dr. Roger Kornberg(2006 Nobel Laureate for Chemistry at the School of Medicine of Stanford University/USA)
Date:14:00~, Thursday, November 20, 2025
Place:International Conference Hall (3F), Humanities and Social Sciences Building (HSSB), Academia Sinica
For more information, please visit the official website at https://www.peace-bridges.net/ .
 
 
 
 
 
 

Training Courses

 
 
 
【Clinical Trial series】Lesson 5—Study design of Phase II clinical trials(In Chinese)(Physical and Video Class)
 
2025-11-18(Tue)10:00~12:00
Dr.Mey Wang
Research Building of Environmental Changes, AS, 6005 Room
 
 
 
   
 
 
 

Video Service

 
 
 
 
Welcome to browse the video service of LSL courses
 
10/27-Turnitin training course for student (In Chinese)
10/27-Turnitin training course for student (In English)
11/4-NGS Workshop 1-Advanced Genomics Technologies and Applications(In Chinese)
11/4-NGS Workshop 2-Supercomputing for NGS analysis(In Chinese)
11/5-NGS Workshop 3-Data Quality Check and Preprocessing(In Chinese)
11/5-NGS Workshop 4-Genetic variant calling and annotation(In Chinese)
11/6-NGS Workshop 6-Old Data, New Discoveries: Reusing Public Biomedical Resources(In Chinese)
 
 
 
 
 
 

Lectures

 
 
 
 
11/11 IMB Seminar
 
Topic:Protein evolution from the origins of life to present-day speciation
Speaker:Dr. Andrei Lupas (Director Department of Protein Evolution, Max Planck Institute for Biology, Germany)
Date:2025-11-11 11:00 - 12:00
Place:1F Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
11/11 IPMB Seminar
 
Topic:Deciphering the interaction between plants and bacterial pathogens: beyond activation and suppression of immunity
Speaker:Dr. Alberto Macho (Principal Investigator, Shanghai Center for Plant Stress Biology (PSC)/ Center for Excellence in Molecular Plant Sciences (CEMPS)/ Chinese Academy of Sciences (CAS), China)
Date:2025-11-11 15:00 - 17:00
Place:Auditorium A134, Agricultural Technology Building, Academia Sinica
 
 
 
 
 
 
 
11/12 GRC Seminar
 
Topic:Signaling metabolites in cancer and immune regulation
Speaker:Hui-Kuan Lin, Academician and Endowed Chair Professor (Duke University School of Medicine, USA)
Date:2025-11-12 10:30 - 12:00
Place:1F Auditorium, Genomics Research Center
 
 
 
 
 
 
 
11/12 ICOB Seminar
 
Topic:Dr. Strangefoot (aka Xenopus) or How I Learned to Stop Worrying and Love Metabolism
Speaker:Dr. Enrique AMAYA (University of Manchester, UK)
Date:2025-11-12 11:00 - 12:00
Place:Auditorium, ICOB
 
 
 
 
 
 
 
11/12 IPMB Seminar
 
Topic:Sociomicrobiolgy: quorum sensing control of cooperation
Speaker:Dr. Everett Peter Greenberg (Professor, Department of Microbiology, University of Washington, USA)
Date:2025-11-12 11:00 - 13:00
Place:Auditorium A134, Agricultural Technology Building, Academia Sinica
 
 
 
 
 
 
 
11/13 BRCAS Seminar
 
Topic:Impacts of Genome Architecture on Mechanisms of Rapid Evolution during Habitat Change
Speaker:Prof. Carol E. Lee (University of Wisconsin-Madison, USA)
Date:2025-11-13 09:30 - 10:30
Place:Auditorium, 1st Floor, Interdisciplinary Research Building
 
 
 
 
 
 
 
11/13 IMB Seminar
 
Topic:Dynamic analysis of coupled gene expression oscillations at the tissue level reveals the “hidden” organization of neurogenesis
Speaker:Dr. Nancy Papalopulu (Professor of Developmental Neuroscience, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK)
Date:2025-11-13 11:00 - 12:00
Place:B1 Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
11/13 IBMS Seminar
 
Topic:ROS-PET Imaging and Microglial Control of Cerebral Blood Flow
Speaker:Dr. Chia-Yi (Alex) Kuan (UVA School of Medicine)
Date:2025-11-13 11:00 - 12:15
Place:B1B Lecture Room, IBMS
 
 
 
 
 
 
 
11/13 NPAS Seminar
 
Topic:N-glycosylation regulates the trafficking and function of excitatory neurotransmitter receptors
Speaker:Dr. Cyril Hanus (INSERM IPNP)
Date:2025-11-13 14:00 - 15:00
Place:1F Auditorium (B106), IST
 
 
 
 
 
 
 
11/14 IMB Seminar
 
Topic:Dynamics of motile cilia for swimming, steering, and synchronization
Speaker:Dr. Benjamin M. Friedrich (Associate Professor, Technical University Dresden, Germany)
Date:2025-11-14 10:30 - 11:30
Place:1F Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
11/14 IBC Seminar
 
Topic:Multi-scale analysis of glycan impact on neuronal surface proteins dynamics and function
Speaker:Dr. Cyril Hanus (Paris-Cité University, France)
Date:2025-11-14 11:00 - 12:00
Place:IBC R209
 
 
 
 
 
 
 
11/17 IPMB Seminar
 
Topic:Dialogues in the Rhizosphere: From Iron Acquisition to Microbial Assembly
Speaker:Dr. Huei-Hsuan Tsai (Postdoctoral Researcher, University of Lausanne, Switzerland)
Date:2025-11-17 10:00 - 12:00
Place:Auditorium A134, Agricultural Technology Building, Academia Sinica
 
 
 
 
 
 
 
11/18 GRC Seminar
 
Topic:Understanding Human Totipotency and Development
Speaker:Dr. Miguel A. Esteban (BGI CELL, China)
Date:2025-11-18 10:30 - 12:00
Place:1F Auditorium, Genomics Research Center
 
 
 
 
 
 
 
11/20 IMB Seminar
 
Topic:Beige adipocyte development and metabolic regulation
Speaker:Dr. Chih-Hao Wang (Assistant Research Fellow, Genomics Research Center, Academia Sinica, Taiwan)
Date:2025-11-20 11:00 - 12:00
Place:1F Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 

Seminars

 
 
 
 
11/20 NPAS Mini-Symposium
 
Topic:Somatosensory Neuroscience
Speaker:Please see the content for more information
Date:2025-11-21 09:20 - 17:30
Place:1F Auditorium (B106), IST
 
 
 
 
 
 

Important Research

 
 
 
 
Innovative gene engineering and drug delivery systems for dendritic cells in cancer immunotherapy
 
Dendritic cells (DCs) play a crucial role in the coordination of immune responses and have emerged as a potential target for cancer immunotherapy.
 
 
 
 
 
 
 
Characterization of BRCA1-Associated Protein-1 (BAP1) Aggregation Properties Induced by Cancer-Associated Mutations
 
These findings provide critical insights into how specific mutations in BAP1 drive aggregation and compromise its tumor-suppressing functions inside the nucleus, thereby contributing to cancer progression.
 
 
 
 
 
 
 
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular L-lactate dynamics
 
Here we introduce R-eLACCO2.1, a red fluorescent extracellular L-lactate biosensor that is superior to previously reported green fluorescent biosensors in in vivo sensitivity to increases in extracellular L-lactate and spectral orthogonality.
 
 
 
 
 
 
 
Functional Interaction of GCM1 and LINC01118 Regulates Syncytiotrophoblast Differentiation
 
Human trophoblast stem (TS) cells differentiate into syncytiotrophoblasts (STBs) through cell-cell fusion, forming the outermost layer of the placental villus to enable nutrient and gas exchange between the mother and fetus.
 
 
 
 
 
 
 
 
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