Period: 2025-11-24~ 2025-12-01

Topic：Who can influence the end of conflict-related sexual violence (CRSV) worldwide? – The power of personal stories and the role of activism
Speaker：Ms. Nadia Murad( 2018 Nobel Peace Laureate and Human Rights Activist, Washington DC/USA)
Date：14:00 ~, Monday, December 1, 2025
Place：Second Conference Room (3F), Humanities and Social Sciences Building (HSSB), Academia Sinica

Topic：Chromatin Dysregulation, a Driver of Oncogenesis
Speaker：Dr. G Greg Wang (Dept. of Pharmacology and Cancer Biology, Duke University School of Medicine)
Date：2025-11-25 11:00 - 12:00
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Transition from Biogenic Amines to Aldehyde Capture: Establishing a Quantitative Analytical Method through Reductive Amination
Speaker：Dr. Shih-Shin Liang (Kaohsiung Medical Univ.)
Date：2025-11-25 11:00 - 12:15
Place：B1B Lecture Room, IBMS

Topic：Leveraging the population history to understand the architecture of complex traits in diverse human populations
Speaker：Dr. Charleston W. K. Chiang (Univ. of Southern California)
Date：2025-11-25 15:00 - 16:15
Place：B1B Lecture Room, IBMS

Topic：Decoding Epigenetic Roadblocks in Cellular Reprogramming
Speaker：Tamer T. Önder教授 (土耳其科曲大學)
Date：2025-11-26 10:30 - 12:00
Place：3F Meeting Room, Genomics Research Center

Topic：Rewiring Biology with E. coli
Speaker：Dr. Hirotada Mori (Visiting Professor, Institute of Molecular Medicine, National Cheng Kung University, Tainan, Taiwan)
Date：2025-11-26 11:00 - 12:00
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：The Brain’s Fuel Dilemma: From Glucose Deficits to Fat Utilization Energetic stress impairs long-range axons and induces inflammation
Speaker：Dr. Hui-Chen Lu (Indiana Univ. Bloomington)
Date：2025-11-28 11:00 - 12:00
Place：1F Auditorium (B106), IST

Topic：Postdoc Seminar: Theory for Optimal Estimation and Control under Resource Limitations and its Applications to Biological Information Processing and Decision-Making
Speaker：Dr. Takehiro Tottori (Special Postdoctoral Researcher, Lab for Neural Computation and Adaptation, RIKEN Center for Brain Science, Japan)
Date：2025-12-01 10:30 - 11:30
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Patterning and Cell Fate in Drosophila Embryos in the Absence of All Maternal Gradients
Speaker：Dr. Eric WIESCHAUS (1995 Nobel Prize Winner, Princeton University, USA)
Date：2025-12-02 09:00 - 10:00
Place：Lecture Hall, National Biotechnology Research Park

Topic：Cargo transport by the dynein/dynactin motor
Speaker：Dr. Andrew Carter (MRC Program Leader, MRC LMB, Cambridge, UK)
Date：2025-12-02 11:00 - 12:00
Place：B1 Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Uncovering Plant Defence Networks using Systems Biology: From Grapevine–Botrytis and Water Stress Studies to the PlantaeViz Platform
Speaker：Dr. José Tomás Matus Picero (Institute for Integrative Systems Biology: Valencia, Spain)
Date：2025-12-03 11:00 - 13:00
Place：Auditorium A134, Agricultural Technology Building, Academia Sinica

Topic：Postdoc Seminar: Genomic and Functional Landscapes of ecDNA-Driven Cancers
Speaker：Dr. Shu Zhang (Postdoctoral Fellow, Paul Mischel’s and Howard Y. Chang’s Lab, Pathology Department, Stanford University)
Date：2025-12-03 11:00 - 12:00
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：The tumor microenvironment in pancreatic cancer – new clinical challenges, but more opportunities
Speaker：Professor Lei Zheng (UT Health San Antonio, USA)
Date：2025-12-03 14:00 - 15:30
Place：1F Auditorium, Genomics Research Center

Topic：The Mutational Landscape of Adrenal Glands with Aldosterone-producing Lesions at Single-cell Resolution
Speaker：Dr. Elena Aisha Azizan (Nat'l Univ. of Malaysia)
Date：2025-12-04 11:00 - 12:15
Place：B1B Lecture Room, IBMS

Topic：Postdoc Seminar: Computational analysis of internal states during memory modification learning in an Alzheimer’s disease mouse model
Speaker：Dr. Mei-Lun Huang (Graduate School of Biostudies, Kyoto University)
Date：2025-12-04 11:00 - 12:00
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Structural biology in the age of AI
Speaker：Dr. Tom C. Terwilliger (Los Alamos National Laboratory, USA)
Date：2025-12-05 11:00 - 12:00
Place：IBC R209

Topic：Plants and Fungi: An Adventure That Began more than 400 Million Years Ago
Speaker：Prof. Paola Bonfante (Professor Emerita, Department of Life Sciences and Biological Systems, University of Torino, Accademia dei Lincei, Italy)
Date：2025-12-08 11:00 - 13:00
Place：Auditorium A134, Agricultural Technology Building, Academia Sinic

Topic：Translation Under Surveillance: Ribosome Quality Control and tRNA Modifications in Cell Physiology
Speaker：Dr. Colin Chih-Chien Wu (RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute)
Date：2025-12-08 11:00 - 12:00
Place：1F Auditorium, Institute of Molecular Biology, Academia Sinica

Topic：Activation mechanism and evolutionary history of NLR proteins in rice
Speaker：Please visit the website for more information
Date：2025-11-25 14:30 - 15:30
Place：Auditorium A134, Agricultural Technology Building, Academia Sinica

Date：2025-11-28 15:00 - 17:15
Place：IBC 103 Auditorium

The ubiquitin-proteasome system (UPS) and macroautophagy/autophagy are two major pathways for maintaining cellular protein homeostasis.

Human trophoblast stem (TS) cells differentiate into syncytiotrophoblasts (STBs) through cell-cell fusion, forming the outermost layer of the placental villus to enable nutrient and gas exchange between the mother and fetus.

Ubiquitin-specific proteases (USPs), comprising the largest deubiquitinase family, are generally thought to have poor discrimination of ubiquitin (Ub) linkage types, but a number of USPs show preference toward certain linkages.

The study uncovered seven irreversible chromosome fusion events shared between phoronids and bryozoans, one of which is also shared with brachiopods. These fusions are absent in other lophotrochozoans such as molluscs, annelids, and nemerteans, providing sequence-independent evidence for the monophyly of lophophorates and demonstrating that these three phyla indeed share a recent common ancestor.

Nearly 70 years after the discovery of the SC, this team also demonstrated for the first time that the true physiological function of SC in meiosis is to suppress MMR, thereby promoting genetic diversity in gamates or fungal sexual spores.

Through genetic screening, we identify the splicing factor Sf3b1 as functioning cell-autonomously in neuronal dendrite growth and maintenance.

Here, using an AI-powered mapping platform, BM-auto (Brain Mapping with Auto-ROI correction), to analyze a Thy1-YFP reporter, we show that different ASD-associated mutations cause distinct circuit abnormalities but share common deficits in the piriform cortex, a region regulating olfactory discrimination and social behavior patterns.

With long-standing expertise in antibody engineering and translational research, Dr. Wu’s team provides a valuable framework to guide innovation in precision medicine, immunotherapy, and infectious-disease control.