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 Date : 2026/06/22 No:387 
 
 
 

Recent News

 
 
System maintenance announcement
 
 
System maintenance announcement
 
Maintenance operations for web services will be held on 6-23 (Tues.). During the maintenance period, the web service will suspend. If any issues are resolved ahead of schedule, the services will be restored earlier. We apologize for any inconvenience.
 
 
 
 
 
 
 
New Books
 
Period:2026-06-22~2026-06-29
 
 
 
 
 
 
 
115 TAEDC PDA eBook Trial
 
115 TAEDC PDA(Patron-Driven Acquisitions)eBook Trial Trial Period:Current until December 31
 
 
 
 
 
 
 
Henry Stewart Talks June recently added
 
 
 
 
 
 
 

Training Courses

 
 
 
【Bioinformatics series】Taiwan Biobank Metabolomics Data Analysis Workshop (in Chinese)(Physical Class)
 
2026-06-24(Wed)14:00~16:00
Dr.Chung-Ke Chang(Chief Strategy Officer)
Ms.Sing-Huei Wu(Data Analyst)
(Taiwan Biobank)
2F Computer classroom, Bldg. D, NBRP
 
 
 
 
【LSL eResources series】EndNote 2025 Essentials (Windows & Mac)(In English)(Video Class)
 
2026-06-25(Thu)14:00~16:00
Mr. Max Lin(Shou Ray Information Service Co., Ltd.)
Online
 
 
 
 
 
 
【Bioinformatics series】Annotation and enrichment analysis(In Chinese)(Physical and Video Class)
 
2026-06-30(Tue)14:00~16:00
Dr.En-Yu Lai(ISS, AS)
Research Building of Environmental Changes, AS, 6005 Room
 
 
 
 
【Bioinformatics series】Metabolomics data analysis I & II(In Chinese)(Physical and Video Class)
 
2026-07-07(Tue)14:00~17:00
Dr.Yu-Jen Liang(ISS, AS)
Research Building of Environmental Changes, AS, 6005 Room
 
 
 
 
   
 
 
 

Lectures

 
 
 
 
06/23 IMB Seminar
 
Topic:Sense and Sensibility in the Changing Brain: Circuit Architecture and Molecular Logic
Speaker:Dr. Kuan Hong Wang (Professor, University of California, San Diego)
Date:2026-06-23 11:00 - 12:00
Place:1F Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
06/24 IMB Seminar
 
Topic:Evolution dynamics and ecological impact of interbacterial antagonism among the human gut microbiota
Speaker:Dr. Benjamin D. Ross (Associate Professor, Dartmouth College)
Date:2026-06-24 11:00 - 12:00
Place:B1 Auditorium, Institute of Molecular Biology, Academia Sinica
 
 
 
 
 
 
 
06/26 IPMB Seminar
 
Topic:Glutamine: A Jack-of-All-Trades in Nitrogen Metabolism
Speaker:Dr. Ming-Hsiun Hsieh (Institute of Plant and Microbial Biology, Academia Sinica)
Date:2026-06-26 10:30 - 11:30
Place:Auditorium A134, Agricultural Technology Building, Academia Sinica
 
 
 
 
 
 
 
06/29 BRCAS Seminar
 
Topic:From Species to Flora: A Fern Odyssey
Speaker:Mr. Cheng-Wei Chen (TIGP, Academia Sinica)
Date:2026-06-29 14:00 - 15:00
Place:Auditorium, 1st Floor,​ Institute of Cellular and Organismic
 
 
 
 
 
 
 
06/30 IBMS Seminar
 
Topic:A Variance‑Regulating microRNA Defines Exceptional Responders and Limits DNA‑Repair Plasticity in Glioblastoma
Speaker:Clark Chin-Chung Chen, MD, PhD (The Warren Alpert Medical School of Brown Unive.)
Date:2026-06-30 11:00 - 12:00
Place:B1B Lecture Room, IBMS
 
 
 
 
 
 
 
07/01 ABRC Seminar
 
Topic:A transcriptional module for auxin-mediated floral initiation
Speaker:Dr. Yunde Zhao (Tata Chancellor’s Endowed Professor, Professor of Cell and Developmental Biology, University of California San Diego, USA)
Date:2026-07-01 13:30 - 15:30
Place:Conference Room A133, Agricultural Technology Building
 
 
 
 
 
 
 
07/02 IPMB Seminar
 
Topic:Dissecting the c-di-GMP Regulatory Network Governing Virulence and Interbacterial Competition in Agrobacterium C58
Speaker:Mr. Xuan Lai (Institute of Plant and Microbial Biology, Academia Sinica)
Date:2026-07-02 15:00 - 16:00
Place:中央研究院植物暨微生物學研究所R106多功能會議室
 
 
 
 
 
 
 
07/02 BRCAS Seminar
 
Topic:The Secret Life of Sponges in Light and Dark Habitats
Speaker:Prof. Nicole de Voogd (Leiden University, Netherlands)
Date:2026-07-02 15:00 - 16:30
Place:Auditorium, 1st Floor, Interdisciplinary Research Building
 
 
 
 
 
 

Seminars

 
 
 
 
Bacterial Cell Wall Minisymposium
 
Speaker:Please see poster
Date:2026-06-26 13:30 - 17:10
Place:IBC R209
 
 
 
 
 
 

Important Research

 
 
 
 
Targeting fibroblast TXNDC5 resolves tumor desmoplasia and PD-1 resistance in colorectal cancer with mesenchymal traits
 
Our findings identify the TXNDC5-TGFBR1 axis as a key orchestrator of the fibrotic shield within the malignant microenvironment and suggest that targeting TXNDC5 in fibroblasts could help overcome immunotherapy resistance in patients with mesenchymal-type colorectal cancer.
 
 
 
 
 
 
 
Precursor gene engineering expands the loop region of the lasso peptide microcin J25
 
In this work, we demonstrated that the MccJ25 biosynthetic enzymes are surprisingly permissive toward insertions in the loop region.
 
 
 
 
 
 
 
Identification of a structural mechanism for prediction and discrimination of substrates for multifunctional GH5 cellulases/hemicellulases
 
This study thus identified a structural mechanism for determining the substrate specificities of GH5 multifunctional cellulases/hemicellulases.
 
 
 
 
 
 
 
Refinement of amino-acid conformation vs. difference density maps in time-resolved serial femtosecond crystallography data analysis
 
Time-resolved crystallography is a revolutionary X-ray diffraction technique by which the structural features of short-lived, transient intermediates of in crystallo reactions can be elucidated.
 
 
 
 
 
 
 
Resveratrol isomers with opposing activities target endonuclease G to modulate neurodegeneration and mitochondrial elimination
 
Mitochondrial endonuclease G (EndoG) is involved in several important cellular processes and has been implicated in multiple diseases.
 
 
 
 
 
 
 
 
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