Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 張耀明 Chang, Yao-Ming

Journal 25

Chowdhury Kaushik, Huang Chia-Lin, Lin I-Ting, Hung Yu-Jen, Lim Khai Lone, Liu Hsing-Wei, Wei Ke-Hsuan, Yang Kai-Chien, (Chang Yao-Ming), Lai Ben Shih-Lei. Immune modulation promotes heart regeneration through macrophage and Granulin functions in medaka. Proceedings of the National Academy of Sciences. 123(16), e2524705123, 2026-04-14. [JCR]　[WOS]
Shao Jheng-Syuan, Lai Alan C., Huang Wei-Chang, Wu Ko-Chien, Chi Po-Yu, (Chang Yao-Ming), Chang Ya-Jen*. Pulmonary fibroblast-derived stem cell factor promotes neutrophilic asthma by augmenting IL-17A production from ILC3s. Journal of Clinical Investigation. 135(16), 1-18, 2025-07-17. [JCR]　[WOS]
Wang Yi-Chuan, Wu Ping-Hsun, Ting Wen-Chieh, Wang Yi-Fu, Yang Ming-Han, Su Tung-Hung, Su Jia-Ying, Sun Hsun-I, Huang Wei-Min, Tsai Pei-Ling, Wernig Gerlinde, Ho Ping-Chih, Wang Limei, Wu Chen-Tu, Chang Yih-Leong, Chen Tseng-Cheng, Meng Tzu-Ching, (Chang Yao-Ming), Lai Shih-Lei, Li Chia-Wei, Ko Tai-Ming, Yang Kai-Chien, Chang Ya-Jen, Chern Yijuang, Kuo Mei-Chuan, Huang Yen-Tsung, Tzeng Yi-Shiuan, Tang Jih-Luh, Chen Shih-Yu*. Single-cell signaling network profiling during redox stress reveals dynamic redox regulation in immune cells. Nature Communications. 16(1), 1-18, 2025-07-01. [JCR]　[WOS]
Chang Chih-Hao, Chou Che-Yu, Raben Timothy G., Chen Shih-Ann, Jong Yuh-Jyh, Wu Jeng-Yih, Yang Shun-Fa, Chen Hsiang-Cheng, Chen Yen-Lin, Chen Ming, Ma Gwo-Chin, Huang Chih-Yang, Wang Tso-Fu, Lee Sing-Lian, Hung Chen-Fang, Pang See-Tong, Widen Erik, (Chang Yao-Ming), Yeh Erh-Chan, Wei Chun-Yu, Chen Chien-Hsiun, Hsu Stephen D. H., Kwok Pui-Yan*. Polygenic height prediction for the Han Chinese in Taiwan. npj Genomic Medicine. 10(1), 1-10, 2025-02-05. [JCR]　[WOS]
Chang Shao Han*, Lin Chen Yi, (Chang Yao Ming), Chen Huan Yuan, Shaw Fu Zen, Shyu Bai Chuang. TEMPORAL PROFILING OF POSTTRAUMATIC STRESS DISORDER (PTSD) EXPLORED BY BRAIN WAVE DYNAMICS, MACHINE LEARNING, AND GENETIC PATTERNS IN A RAT MODEL SIMULATING PTSD. International Journal of Neuropsychopharmacology. 28(Supplement_1), i218-i219, 2025-02-12. [JCR]　[WOS]
Shen Chiu-Lun, Tsai Yu-Young, Chou Shen-Ju, (Chang Yao-Ming), Tarn Woan-Yuh*. RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar foliation. Communications Biology. 7(1), 1712, 2024-12-30. [JCR]　[WOS]
Lu Wen-Hsin, Chang Tzu-Tung, (Chang Yao-Ming), Liu Yi-Hsiang, Lin Chia-Hsuan, Suen Ching-Shu, Hwang Ming-Jing, Huang Yi-Shuian*. CPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity. Journal of Biomedical Science. 31(1), 69, 2024-07-11. [JCR]　[WOS]
Chen Chih-Kuan, (Chang Yao-Ming), Jiang Ting-Xin, Yue ZhiCao, Liu Tzu-Yu, Lu Jiayi, Yu Zhou, Lin Jinn-Jy, Vu Trieu-Duc, Huang Tao-Yu, Harn Hans I-Chen, Ng Chen Siang, Wu Ping, Chuong Cheng-Ming, Li Wen‐Hsiung. Conserved regulatory switches for the transition from natal down to juvenile feather in birds. Nature Communications. 15(1), 4174, 2024-05-16. [JCR]　[WOS]
Huang FL, (Chang YM), Lin CY, Yu SJ, Fu JT, Chou TY, Yeh SW, Liao EC, Li CL*. Regulating TKT activity inhibits proliferation of human acute lymphoblastic leukemia cells. American journal of cancer research. 14(2), 679-695, 2024-02-15.　[WOS]
Chou Wen-Cheng, Chen Wei-Ting, Kuo Chun-Tse, (Chang Yao-Ming), Lu Yen-Shen, Li Chia-Wei, Hung Mien-Chie, Shen Chen-Yang*. Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer. Cell Reports. 43(1), 113641, 2024-01-23. [JCR]　[WOS]
Lin Chia-Yeh, (Chang Yao-Ming), Tseng Hsin-Yi, Shih Yen-Ling, Yeh Hsiao-Hui, Liao You-Rou, Tang Han-Hsuan, Hsu Chia-Ling, Chen Chien-Chang, Yan Yu-Ting*, Kao Cheng-Fu*. Epigenetic regulator RNF20 underlies temporal hierarchy of gene expression to regulate postnatal cardiomyocyte polarization. Cell Reports. 42(11), 113416, 2023-11-28. [JCR]　[WOS]
Siew Jian Jing, Chen Hui-Mei, Chiu Feng-Lan, Lee Chia-Wei, (Chang Yao-Ming), Chen Hung-Lin, Nguyen Thi Ngoc Anh, Liao Hung-Ting, Liu Mengyu, Hagar Hsiao-Tien, Sun Yung-Chen, Lai Hsing-Lin, Kuo Min-Hao, Blum David, Buée Luc, Jin Lee-Way, Chen Shih-Yu, Ko Tai-Ming, Huang Jie-rong, Kuo Hung-Chih, Liu Fu-Tong, Chern Yijuang*. Galectin-3 aggravates microglial activation and tau transmission in tauopathy. Journal of Clinical Investigation. e165523, 1, 2023-11-31. [JCR]　[WOS]
Chang Shao-Han, (Chang Yao-Ming), Chen Huan-Yuan, Shaw Fu-Zen, Shyu Bai-Chuang*. Time-course analysis of frontal gene expression profiles in the rat model of posttraumatic stress disorder and a comparison with the conditioned fear model. Neurobiology of Stress. 2352-2895(23), 100569, 2023-09-20. [JCR]　[WOS]
Wei Ke-Hsuan, Lin I-Ting, Chowdhury Kaushik, Lim Khai Lone, Liu Kuan-Ting, Ko Tai-Ming, (Chang Yao-Ming), Yang Kai-Chien, Lai Shih-Lei*. Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration. eLife. 12, e84679, 2023-07-27. [JCR]　[WOS]
Chuang Tzu-Wei, Su Chun-Hao, Wu Pei-Yu, (Chang Yao-Ming), Tarn Woan-Yuh*. LncRNA HOTAIRM1 functions in DNA double-strand break repair via its association with DNA repair and mRNA surveillance factors. Nucleic Acids Research. gkad143, 1, 2023-03-07. [JCR]　[WOS]
Weng Yu-Ting, (Chang Yao-Ming), Chern Yijuang*. The Impact of Dysregulated microRNA Biogenesis Machinery and microRNA Sorting on Neurodegenerative Diseases. International Journal of Molecular Sciences. 24(4), 3443, 2023-02-08. [JCR]　[WOS]
Hsiang-Chi Huang, Shih-Han Wang, Guo-Chen Fang, Wen-Cheng Chou, Chun-Che Liao, Cheng-Pu Sun, Jia-Tsrong Jan, Hsiu-Hua Ma, Hui-Ying Ko, Yi-An Ko, Ming-Tsai Chiang, Jian-Jong Liang, Chun-Tse Kuo, Te-An Lee, Diego Morales-Scheihing, Chen-Yang Shen, Shih-Yu Chen, Louise D. McCullough, Mi-Hua Tao, Yi-Ling Lin, (Yao-Ming Chang)*, Shu-Ping Wang*, Yun-Ju Lai*, and Chia-Wei Li*. Upregulation of PD‐L1 by SARS‐CoV‐2 promotes immune evasion. JOURNAL OF MEDICAL VIROLOGY. 95(2), e28478, 2023-01-07. [JCR]　[WOS]
Yu-Shuen Tsai#, (Yao-Ming Chang)#, Yang-Mooi Lim, Soon-Keng Cheong, I-Fang Chung*, Chee-Yin Wong*. Generating transcriptional regulatory networks from time-ordered stem cell differentiation RNA sequencing data. STAR Protocols. 3(3), 101541, 2022-09-16. [JCR]　[WOS]
Yeh Hsiao-hui, (Chang Yao-Ming), Chang Yu-Wang, Lu Mei-Yeh Jade, Chen Yi-Hua, Lee Chia-Che, Chen Chien-Chang*. Multiomic analyses reveal enriched glycolytic processes in β-myosin heavy chain-expressed cardiomyocytes in early cardiac hypertrophy. Journal of Molecular and Cellular Cardiology Plus. 1, 100011, 2022-09. [JCR]　[WOS]
Su-Ying Yeh, Lin Hsin-Hung, (Chang Yao-Ming), Chang Yu-Lun, Chang Chao-Kang, Huang Yi-Cin, Ho Yi-Wen, Lin Chu-Yin, Zheng Jun-Ze, Jane Wann-Neng, Ng Chun-Yeung, Lu Mei-Yeh, Lai I-Ling, To Kin-Ying, Li Wen-Hsiung, Ku Maurice S B*. Maize Golden2-like transcription factors boost rice chloroplast development, photosynthesis and grain yield. Plant Physiology. 118, kiab511, 2022-01. [JCR]　[WOS]
Hsieh Wan-Chen, Lai En-Yu, Liu Yu-Ting, Wang Yi-Fu, Tzeng Yi-Shiuan, Cui Lu, Lai Yun-Ju, Huang Hsiang-Chi, Huang Jia-Hsin, Ni Hung-Chih, Tsai Dong-Yan, Liang Jian-Jong, Liao Chun-Che, Lu Ya-Ting, Jiang Laurence, Liu Ming-Tsan, Wang Jann-Tay, Chang Sui-Yuan, Chen Chung-Yu, Tsai Hsing-Chen, (Chang Yao-Ming), Wernig Gerlinde, Li Chia-Wei, Lin Kuo-I, Lin Yi-Ling, Tsai Huai-Kuang, Huang Yen-Tsung, Chen Shih-Yu*. NK cell receptor and ligand composition influences the clearance of SARS-CoV-2. Journal of Clinical Investigation. 131(21), e146408, 2021-11-01. [JCR]　[WOS]
Lu Wen-Hsin, (Chang Yao-Ming), Huang Yi-Shuian*. Alternative Polyadenylation and Differential Regulation of Ucp1: Implications for Brown Adipose Tissue Thermogenesis Across Species. Frontiers in Pediatrics. 8, 612279, 2021-02-09. [JCR]　[WOS]
Sudhakar Janaki N., Lu Hsueh-Han, Chiang Hung-Yu, Suen Ching-Shu, Hwang Ming-Jing, Wu Sung-Yu, Shen Chia-Ning, (Chang Yao-Ming), Li Fu-An, Liu Fu-Tong, Shui Jr-Wen*. Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas. Nature Communications. 11(1), 4286, 2020-08-27. [JCR]　[WOS]
Chee-Yin Wong, (Yao-Ming Chang), Yu-Shuen Tsai, Wailap Victor Ng, Soon-Keng Cheong, Ting-Yu Chang, I-Fang Chung*, Yang-Mooi Lim*. Decoding the differentiation of mesenchymal stem cells into mesangial cells at the transcriptomic level. BMC GENOMICS. 21(1), 2020-07-07. [JCR]　[WOS]
Lin Chen-Ching, (Chang Yao-Ming), Pan Cheng-Tsung, Chen Chien-Chang, Ling Li, Tsao Ku-Chi, Yang Ruey-Bing, Li Wen-Hsiung*. Functional Evolution of Cardiac MicroRNAs in Heart Development and Functions. Molecular Biology and Evolution. 31(10), 2722-2734, 2014-10. [JCR]

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