Research Findings
Journal 14
- Wang PY, Kuo TY, Wang LH, Liang WS, Wang, GS. Loss of MBNL1 mediated retrograde BDNF signaling in myotonic dystrophy brain. ACTA NEUROPATHOLOGICA COMMUNICATIONS. 11, 44-56, 2023-03-15. [JCR] [WOS]
- Lee-Hsin Wang , Chien-Yu Lin, Yu-Mei Lin, Luc Buée, Nicolas Sergeant, David Blum, Yijuang Chern , Guey-Shin Wang. Calpain-2 Mediates MBNL2 Degradation and a Developmental RNA Processing Program in Neurodegeneration. JOURNAL OF NEUROSCIENCE. 42, 5102-5114, 2022-06-22. [JCR] [WOS]
- Chang KT, Wang LH, Lin YM, Cheng CF, Wang GS. CELF1 promotes vascular endothelial growth factor degradation resulting in impaired microvasculature in heart failure. FASEB JOURNAL. 35(5), e21512, 2021-05. [JCR] [WOS]
- Wang PY, Chang KT, Lin YM, Kuo TY, Wang GS*. Ubiquitination of MBNL1 Is Required for Its Cytoplasmic Localization and Function in Promoting Neurite Outgrowth. CELL REPORTS. 22, 2294-2306, 2018-02. [JCR] [WOS]
- Chang KT, Cheng CF, King PC, Liu SY, Wang GS*. CELF1 Mediates Connexin 43 mRNA Degradation in Dilated Cardiomyopathy. CIRCULATION RESEARCH. 121, 1140-1152, 2017. [JCR] [WOS]
- Wang PY, Lin YM, Wang LH, Kuo TY, Cheng SJ, Wang GS*. Reduced cytoplasmic MBNL1 is an early event in a brain-specific mouse model of myotonic dystrophy. HUMAN MOLECULAR GENETICS. 26(12), 2247-2257, 2017. [JCR] [WOS]
- Verma SK, Deshmukh V, Liu P, Nutter CA, Espejo R, Hung ML, Wang GS, Yeo GW, Kuyumcu-Martinez MN. Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling. J Biol Chem.. 288(49), 35372-35386, 2013-12. [JCR] [WOS]
- Wang GS, Kuyumcu-Martinez MN, Sarma S, Mathur N, Wehrens XH, Cooper TA. PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1. JOURNAL OF CLINICAL INVESTIGATION. 119(12), 3797-3806, 2009-12. [JCR] [WOS]
- Wang GS, Kearney DL, De Biasi M, Taffet G, Cooper TA. Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy. JOURNAL OF CLINICAL INVESTIGATION. 117(10), 2802-2811, 2007. [JCR] [WOS]
- Kuyumcu-Martinez NM, Wang GS, Cooper TA. Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation. MOLECULAR CELL. 28(1), 68-78, 2007. [JCR] [WOS]
- Wang GS, Cooper TA. Splicing in disease: disruption of the splicing code and the decoding machinery. NATURE REVIEWS GENETICS. 8(10), 749-61, 2007. [JCR] [WOS]
- Lin CW, Huang TN, Wang GS, Kuo TY, Yen TY, Hsueh YP. Neural activity- and development-dependent expression and distribution of CASK interacting nucleosome assembly protein in mouse brain. The Journal of comparative neurology. 494(4), 606-19, 2006. [JCR] [WOS]
- Wang TF, Ding CN, Wang GS, Luo SC, Lin YL, Ruan Y, Hevner R, Rubenstein JL, Hsueh YP. Identification of Tbr-1/CASK complex target genes in neurons. Journal of neurochemistry. 91(6), 1483-92, 2004. [JCR] [WOS]
- Wang GS, Hong CJ, Yen TY, Huang HY, Ou Y, Huang TN, Jung WG, Kuo TY, Sheng M, Wang TF, Hsueh YP. Transcriptional modification by a CASK-interacting nucleosome assembly protein. Neuron. 42(1), 113-28, 2004. [JCR] [WOS]