Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 林宜玲 Lin, Yi-Ling

Journal 145

Ko HY, Li YT, Yu HP, Li YY, Chiang MT, Simanjuntak Y, Lee YL, Dai SS, Chung PJ, Yu GY, Chao DY, Lin YL. Emergence and increased epidemic potential of dengue variants with the NS5(V357E) mutation after consecutive years of transmission. iScience. 27(11), 110899, 2024-11.
Li YT, Ko HY, Hughes J, Liu MT, Lin YL, Hampson K, Brunker K. From emergence to endemicity of highly pathogenic H5 avian influenza viruses in Taiwan. Nature communications. 15(1), 9348, 2024-10.
Arifin JC, Tsai BY, Chen CY, Chu LW, Lin YL, Lee CH, Chiou A, Ping YH. Quantification of the interaction forces between dengue virus and dopamine type-2 receptor using optical tweezers. Virology journal. 21(1), 215, 2024-09.
Chang YH, Hsu MF, Chen WN, Wu MH, Kong WL, Lu MJ, Huang CH, Chang FJ, Chang LY, Tsai HY, Tung CP, Yu JH, Kuo Y, Chou YC, Bai LY, Chang YC, Chen AY, Chen CC, Chen YH, Liao CC, Chang CS, Liang JJ, Lin YL, Angata T, Hsu SD, Lin KI. Functional and structural investigation of a broadly neutralizing SARS-CoV-2 antibody. JCI insight. 9(10), e179726, 2024-05.
Lee IJ, Lan YH, Wu PY, Wu YW, Chen YH, Tseng SC, Kuo TJ, Sun CP, Jan JT, Ma HH, Liao CC, Liang JJ, Ko HY, Chang CS, Liu WC, Ko YA, Chen YH, Sie ZL, Tsung SI, Lin YL, Wang IH, Tao MH. A receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern. Emerging microbes & infections. 12(1), 2149353, 2023-12. [JCR]
Yang CF, Liao CC, Hsu HW, Liang JJ, Chang CS, Ko HY, Chang RH, Tang WC, Chang MH, Wang IH, Lin YL. Human ACE2 protein is a molecular switch controlling the mode of SARS-CoV-2 transmission. Journal of biomedical science. 30(1), 87, 2023-10.
Chiang HL, Liang KH, Lu RM, Kuo TW, Lin YL, Wu HC. Broadly neutralizing human antibodies against Omicron subvariants of SARS-CoV-2. Journal of biomedical science. 30(1), 59, 2023-07.
Yang CW, Hsu HY, Lee YZ, Jan JT, Chang SY, Lin YL, Yang RB, Chao TL, Liang JJ, Lin SJ, Liao CC, Chang CS, Sytwu HK, Hung MS, Chen CT, Lee SJ. Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin. Biochemical pharmacology. 215, 115688, 2023-07. [JCR]　[WOS]
Huang YF, Hsu FC, Wu JJ, Lin YL, Liu MT, Yang CH, Kuo HS, Chen YJ, Cheng CY, Lin HH, Liao CC, Chang CS, Liang JJ, Cheng WY, Huang JC, Chen CP, Cheng SH, Lin YC, Yang SH, Chou YJ. Longitudinal neutralizing antibody responses after SARS-CoV-2 infection: A convalescent cohort study in Taiwan. Journal of microbiology, immunology, and infection. 56(3), 506-515, 2023-06.
Yen LC, Chen HW, Ho CL, Lin CC, Lin YL, Yang QW, Chiu KC, Lien SP, Lin RJ, Liao CL. Neutralizing antibodies targeting a novel epitope on envelope protein exhibited broad protection against flavivirus without risk of disease enhancement. Journal of biomedical science. 30(1), 41, 2023-06. [JCR]　[WOS]
Ko HY, Li YT, Li YY, Chiang MT, Lee YL, Liu WC, Liao CC, Chang CS, Lin YL. Optimization and Improvement of qPCR Detection Sensitivity of SARS-CoV-2 in Saliva. Microbiology spectrum. 11(3), e0464022, 2023-05.
Lu RM, Liang KH, Chiang HL, Hsu FF, Lin HT, Chen WY, Ke FY, Kumari M, Chou YC, Tao MH, Yi-Ling Lin, Wu HC. Broadly neutralizing antibodies against Omicron variants of SARS-CoV-2 derived from mRNA-lipid nanoparticle-immunized mice. Heliyon. 9(5), e15587, 2023-04.
Huang HC, Wang SH, Fang GC, Chou WC, Liao CC, Sun CP, Jan JT, Ma HH, Ko HY, Ko YA, Chiang MT, Liang JJ, Kuo CT, Lee TA, Morales-Scheihing D, Shen CY, Chen SY, McCullough LD, Cui L, Wernig G, Tao MH, Lin YL, Chang YM, Wang SP, Lai YJ, Li CW. Upregulation of PD-L1 by SARS-CoV-2 promotes immune evasion. Journal of medical virology. 95(2), e28478, 2023-01.
Wang S, Wang CY, Kuo HK, Peng WJ, Huang JH, Kuo BS, Lin F, Liu YJ, Liu Z, Wu HT, Ding S, Hou KL, Cheng J, Yang YT, Jiang MH, Wang MS, Chen T, Xia WG, Lin E, Hung CH, Chen HJ, Shih Z, Lin YL, Ryan V, Hu MM, Heppner DG, Malherbe DC, Periasamy S, Kuzmina N, Subramani C, Hellerstein M, Monath TP, Rumyantsev A, Bukreyev A, Guirakhoo F. A novel RBD-protein/peptide vaccine elicits broadly neutralizing antibodies and protects mice and macaques against SARS-CoV-2. Emerging microbes & infections. 11(1), 2724-2734, 2022-12. [JCR]
Tang WC, Liu YT, Yeh CH, Lu CH, Tu CH, Lin YL, Lin YC, Hsu TL, Gao L, Chang SW, Chen P, Chen BC. Optogenetic manipulation of cell migration with high spatiotemporal resolution using lattice lightsheet microscopy. Communications biology. 5(1), 879, 2022-08. [JCR]
Lee IJ, Sun CP, Wu PY, Lan YH, Wang IH, Liu WC, Yuan JP, Chang YW, Tseng SC, Tsung SI, Chou YC, Kumari M, Lin YS, Chen HF, Chen TY, Lin CC, Chiu CW, Hsieh CH, Chuang CY, Cheng CM, Lin HT, Chen WY, Hsu FF, Hong MH, Liao CC, Chang CS, Liang JJ, Ma HH, Chiang MT, Liao HN, Ko HY, Chen LY, Ko YA, Yu PY, Yang TJ, Chiang PC, Hsu ST, Lin YL, Lee CC, Wu HC, Tao MH. A booster dose of Delta x Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants. Journal of biomedical science. 29(1), 49, 2022-07. [JCR]
Lee YZ, Hsu HY, Yang CW, Lin YL, Chang SY, Yang RB, Liang JJ, Chao TL, Liao CC, Kao HC, Chang JY, Sytwu HK, Chen CT, Lee SJ. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b. Pharmaceutics. 14(7), 1511, 2022-07. [JCR]
Nicholson Martin W., Huang Ching-Ying, Wang Jyun-Yuan, Ting Chien-Yu, Cheng Yu-Che, Chan Darien Z. H., Lee Yi-Chan, Hsu Ching-Chuan, Hsu Yu-Hung, Chang Cindy M. C., Hsieh Marvin L., Cheng Yuan-Yuan, Lin Yi-Ling, Chen Chien-Hsiun, Wu Ying-Ta, Hacker Timothy A., Wu Joseph C., Kamp Timothy J., Hsieh Patrick C. H. Cardio- and Neurotoxicity of Selected Anti-COVID-19 Drugs. Pharmaceuticals. 15(6), 765, 2022-06. [JCR]
Huang CY, Nicholson MW, Wang JY, Ting CY, Tsai MH, Cheng YC, Liu CL, Chan DZH, Lee YC, Hsu CC, Hsu YH, Yang CF, Chang CMC, Ruan SC, Lin PJ, Lin JH, Chen LL, Hsieh ML, Cheng YY, Hsu WT, Lin YL, Chen CH, Hsu YH, Wu YT, Hacker TA, Wu JC, Kamp TJ, Hsieh PCH. Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons. Cell reports. 39(1), 110643, 2022-04. [JCR]
Wang Chang Yi, Hwang Kao-Pin, Kuo Hui-Kai, Peng Wen-Jiun, Shen Yea-Huei, Kuo Be-Sheng, Huang Juin-Hua, Liu Hope, Ho Yu-Hsin, Lin Feng, Ding Shuang, Liu Zhi, Wu Huan-Ting, Huang Ching-Tai, Lee Yuarn-Jang, Liu Ming-Che, Yang Yi-Ching, Lu Po-Liang, Tsai Hung-Chin, Lee Chen-Hsiang, Shi Zhi-Yuan, Liu Chun-Eng, Liao Chun-Hsing, Chang Feng-Yee, Chen Hsiang-Cheng, Wang Fu-Der, Hou Kuo-Liang, Cheng Jennifer, Wang Min-Sheng, Yang Ya-Ting, Chiu Han-Chen, Jiang Ming-Han, Shih Hao-Yu, Shen Hsuan-Yu, Chang Po-Yen, Lan Yu-Rou, Chen Chi-Tian, Lin Yi-Ling, Liang Jian-Jong, Liao Chun-Che, Chou Yu-Chi, Morris Mary Kate, Hanson Carl V., Guirakhoo Farshad, Hellerstein Michael, Yu Hui-Jing, King Chwan-Chuen, Kemp Tracy, Heppner D. Gray, Monath Thomas P. A multitope SARS-CoV-2 vaccine provides long-lasting B cell and T cell immunity against Delta and Omicron variants. Journal of Clinical Investigation. 132(10), e157707, 2022-03. [JCR]
Chang Jer-Hwa, Chiou Jeng-Fong, Hung Ching-Sheng, Liu Ming-Che, Chang Hui-Wen, Hong Shiao-Ya, Wang Cheng-Yi, Lin Yi-Ling, Hsieh Yi-Chen, Chung Chi-Li, Su Ying-Shih, Hsiao Shu-Tai Shen, Liu Doresses, Liang Jian-Jong, Liao Chun-Che, Chang Chih-Shin, Lai Kevin Shu-Leung, Chuang Han-Chuan, Chien Ko-Ling, Wu Wei-Ciao, Lee Yuan-Chii G., Lin Sey-En, Shen Yung-Kang, Hsu Chiung-Fang, Wang Jude Chu-Chun, Hsiao Shih-Hsin. Humoral Immunogenicity and Reactogenicity of the Standard ChAdOx1 nCoV-19 Vaccination in Taiwan. Vaccines. 10(2), 312, 2022-02. [JCR]
Lim Chong Wei, Vao-soongnern Visit, Nimmanpipug Piyarat, Tayapiwatana Chatchai, Lin Jung-Hsin, Lin Yi-Ling, Yee Chee Hui, Md Zain Sharifuddin, Abd Rahman Noorsaadah, Sanghiran Lee Vannajan. Molecular dynamics simulations and Gaussian network model for designing antibody mimicking protein towards dengue envelope protein. Journal of Molecular Liquids. 346, 118086, 2022-01. [JCR]
Chiu H, Chiu HP, Yu HP, Lin LH, Chen ZP, Lin YL, Lin RJ. Zinc Finger Protein ZFP36L1 Inhibits Flavivirus Infection by both 5'-3' XRN1 and 3'-5' RNA-Exosome RNA Decay Pathways. Journal of virology. 96(1), e0166521, 2022-01. [JCR]
Liang KH, Chiang PY, Ko SH, Chou YC, Lu RM, Lin HT, Chen WY, Lin YL, Tao MH, Jan JT, Wu HC. Antibody cocktail effective against variants of SARS-CoV-2. Journal of biomedical science. 28(1), 80, 2021-11. [JCR]
Hsieh WC, Lai EY, Liu YT, Wang YF, Tzeng YS, Cui L, Lai YJ, Huang HC, Huang JH, Ni HC, Tsai DY, Liang JJ, Liao CC, Lu YT, Jiang L, Liu MT, Wang JT, Chang SY, Chen CY, Tsai HC, Chang YM, Wernig G, Li CW, Lin KI, Lin YL, Tsai HK, Huang YT, Chen SY. NK cell receptor and ligand composition influences the clearance of SARS-CoV-2. The Journal of clinical investigation. 131(21), e146408, 2021-11. [JCR]
Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW. Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro. EBioMedicine. 74, 103712, 2021-11. [JCR]
Liang, J.-J.*, C.-C. Liao, C.-S. Chang, C.-Y. Lee, S.-Y. Chen, S.-B. Huang, Y.-F. Yeh, K. J. Singh, H.-c. Kuo*, Y.-L. Lin*, and K.-M. Lu*. The effectiveness of far-ultraviolet (UVC) light prototype devices with different wavelengths on disinfecting SARS-CoV-2. Applied Sciences. 11, 10661, 2021-11.
Yang MH, Hu CC, Wong CH, Liang JJ, Ko HY, He MH, Lin YL, Lin NS, Hsu YH. Convenient Auto-Processing Vector Based on Bamboo Mosaic Virus for Presentation of Antigens Through Enzymatic Coupling. Frontiers in immunology. 12, 739837, 2021-10. [JCR]
Huang HC, Liao CC, Wang SH, Lee IJ, Lee TA, Hsu JM, Kuo CT, Wang J, Hsieh WC, Chang SJ, Chen SY, Tao MH, Lin YL, Lai YJ, Li CW. Hyperglycosylated spike of SARS-CoV-2 gamma variant induces breast cancer metastasis. American journal of cancer research. 11(10), 4994-5005, 2021-10. [JCR]
Hsieh SM, Liu MC, Chen YH, Lee WS, Hwang SJ, Cheng SH, Ko WC, Hwang KP, Wang NC, Lee YL, Lin YL, Shih SR, Huang CG, Liao CC, Liang JJ, Chang CS, Chen C, Lien CE, Tai IC, Lin TY. Safety and immunogenicity of CpG 1018 and aluminium hydroxide-adjuvanted SARS-CoV-2 S-2P protein vaccine MVC-COV1901: interim results of a large-scale, double-blind, randomised, placebo-controlled phase 2 trial in Taiwan. The Lancet. Respiratory medicine. 9, 1396-1406, 2021-10.
Su SC, Yang TJ, Yu PY, Liang KH, Chen WY, Yang CW, Lin HT, Wang MJ, Lu RM, Tso HC, Chung MJ, Hsieh TY, Chang YL, Lin SC, Hsu FY, Ke FY, Wu YH, Hwang YC, Liu IJ, Liang JJ, Liao CC, Ko HY, Sun CP, Wu PY, Jan JT, Chang YC, Lin YL, Tao MH, Hsu SD, Wu HC. Structure-guided antibody cocktail for prevention and treatment of COVID-19. PLoS pathogens. 17(10), e1009704, 2021-10. [JCR]
Kulkarni R, Chen WC, Lee Y, Kao CF, Hu SL, Ma HH, Jan JT, Liao CC, Liang JJ, Ko HY, Sun CP, Lin YS, Wang YC, Wei SC, Lin YL, Ma C, Chao YC, Chou YC, Chang W. Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters. PloS one. 16(9), e0257191, 2021-09. [JCR]
Sun CP, Jan JT, Wang IH, Ma HH, Ko HY, Wu PY, Kuo TJ, Liao HN, Lan YH, Sie ZL, Chen YH, Ko YA, Liao CC, Chen LY, Lee IJ, Tsung SI, Lai YJ, Chiang MT, Liang JJ, Liu WC, Wang JR, Yuan JP, Lin YS, Tsai YC, Hsieh SL, Li CW, Wu HC, Ko TM, Lin YL, Tao MH. Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19. PLoS pathogens. 17(8), e1009758, 2021-08. [JCR]
Hsu HY, Yang CW, Lee YZ, Lin YL, Chang SY, Yang RB, Liang JJ, Chao TL, Liao CC, Kao HC, Wu SH, Chang JY, Sytwu HK, Chen CT, Lee SJ. Remdesivir and Cyclosporine Synergistically Inhibit the Human Coronaviruses OC43 and SARS-CoV-2. Frontiers in pharmacology. 12, 706901, 2021-08. [JCR]
Wang HI, Chuang ZS, Kao YT, Lin YL, Liang JJ, Liao CC, Liao CL, Lai MMC, Yu CY. Small Structural Proteins E and M Render the SARS-CoV-2 Pseudovirus More Infectious and Reveal the Phenotype of Natural Viral Variants. International journal of molecular sciences. 22(16), 9087, 2021-08. [JCR]
Du PX, Chou YY, Santos HM, Keskin BB, Hsieh MH, Ho TS, Wang JY, Lin YL, Syu GD. Development and Application of Human Coronavirus Protein Microarray for Specificity Analysis. Analytical chemistry. 93(21), 7690-7698, 2021-07. [JCR]
Guo JY, Liu IJ, Lin HT, Wang MJ, Chang YL, Lin SC, Liao MY, Hsu WC, Lin YL, Liao JC, Wu HC. Identification of COVID-19 B-cell epitopes with phage-displayed peptide library. Journal of biomedical science. 28(1), 43, 2021-07. [JCR]　[WOS]
Lai YJ, Chao CH, Liao CC, Lee TA, Hsu JM, Chou WC, Wang J, Huang HC, Chang SJ, Lin YL, Li CW. Epithelial-mesenchymal transition induced by SARS-CoV-2 required transcriptional upregulation of Snail. American journal of cancer research. 11(5), 2278-2290, 2021-05. [JCR]　[WOS]
Lien Chia-En, Lin Yi-Jiun, Chen Charles, Lian Wei-Cheng, Kuo Tsun-Yung, Campbell John D., Traquina Paula, Lin Meei-Yun, Liu Luke Tzu-Chi, Chuang Ya-Shan, Ko Hui-Ying, Liao Chun-Che, Chen Yen-Hui, Jan Jia-Tsrong, Ma Hsiu-Hua, Sun Cheng-Pu, Lin Yin-Shiou, Wu Ping-Yi, Wang Yu-Chiuan, Tao Mi-Hua, Lin Yi-Ling. CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge. Scientific Reports. 11(1), 8761, 2021-04. [JCR]　[WOS]
Chen Ting, Fei Cheng-Yin, Chen Yi-Ping, Sargsyan Karen, Chang Chun-Ping, Yuan Hanna S., Lim Carmay. Synergistic Inhibition of SARS-CoV-2 Replication Using Disulfiram/Ebselen and Remdesivir. ACS Pharmacology & Translational Science. 4(2), 898-907, 2021-04. [JCR]　[WOS]
Wei CY, Yang JH, Yeh EC, Tsai MF, Kao HJ, Lo CZ, Chang LP, Lin WJ, Hsieh FJ, Belsare S, Bhaskar A, Su MW, Lee TC, Lin YL, Liu FT, Shen CY, Li LH, Chen CH, Wall JD, Wu JY, Kwok PY. Genetic profiles of 103,106 individuals in the Taiwan Biobank provide insights into the health and history of Han Chinese. NPJ genomic medicine. 6(1), 10, 2021-02. [JCR]　[WOS]
Sargsyan Karen, Lin Chien-Chu, Chen Ting, Grauffel Cédric, Chen Yi-Ping, Yang Wei-Zen, Liang Jian-Jong, Liao Chun-Che, Lin Yi-Ling, Yuan Hanna S., Lim Carmay. Correction: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors. Chemical Science. 12(17), 6210-6210, 2021. [JCR]　[WOS]
Tsai YC, Tang WC, Low CSL, Liu YT, Wu JS, Lee PY, Chen LQ, Lin YL, Kanchanawong P, Gao L, Chen BC. Rapid high resolution 3D imaging of expanded biological specimens with lattice light sheet microscopy. Methods (San Diego, Calif.). 174,11-19, 2020-03. [JCR]　[WOS]
Tsai Keng-Chang, Huang Yi-Chia, Liaw Chia-Ching, Tsai Chia-I, Chiou Chun-Tang, Lin Chien-Jung, Wei Wen-Chi, Lin Sunny Jui-Shan, Tseng Yu-Hwei, Yeh Kuo-Ming, Lin Yi-Ling, Jan Jia-Tsrong, Liang Jian-Jong, Liao Chun-Che, Chiou Wen-Fei, Kuo Yao-Haur, Lee Shen-Ming, Lee Ming-Yung, Su Yi-Chang. A traditional Chinese medicine formula NRICM101 to target COVID-19 through multiple pathways: A bedside-to-bench study. Biomedicine & Pharmacotherapy. 133, 111037, 2020. [JCR]　[WOS]
Chen Wei-Chia, Simanjuntak Yogy, Chu Li-Wei, Ping Yueh-Hsin, Lee Yi-Ling, Lin Yi-Ling, Li Wen-Shan. Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections. Journal of Medicinal Chemistry. 63(3), 1313-1327, 2020. [JCR]　[WOS]
Su Chan-I, Kao Yu-Ting, Chang Chao-Chen, Chang Yao, Ho Tzong-Shiann, Sun H. Sunny, Lin Yi-Ling, Lai Michael M. C., Liu Yu-Huei, Yu Chia-Yi. DNA-induced 2′3′-cGAMP enhances haplotype-specific human STING cleavage by dengue protease. Proceedings of the National Academy of Sciences. 117(27), 15947-15954, 2020.　[WOS]
Yang CW, Lee YZ, Hsu HY, Jan JT, Lin YL, Chang SY, Peng TT, Yang RB, Liang JJ, Liao CC, Chao TL, Pang YH, Kao HC, Huang WZ, Lin JH, Chang CP, Niu GH, Wu SH, Sytwu HK, Chen CT, Lee SJ. Inhibition of SARS-CoV-2 by Highly Potent Broad-Spectrum Anti-Coronaviral Tylophorine-Based Derivatives. Frontiers in pharmacology. 11, 606097, 2020. [JCR]　[WOS]
Sargsyan Karen, Lin Chien-Chu, Chen Ting, Grauffel Cédric, Chen Yi-Ping, Yang Wei-Zen, Yuan Hanna S., Lim Carmay. Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors. Chemical Science. 11(36), 9904-9909, 2020. [JCR]　[WOS]
Huang Ping-Han, Tsai Hsiao-Han, Liao Bo-Hung, Lin Yi-Ling, Jan Jia-Tsrong, Tao Mi-Hua, Chou Yu-Chi, Hu Che-Ming Jack, Chen Hui-Wen. Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain. Human Vaccines & Immunotherapeutics. 17(3), 654-655, 2020. [JCR]　[WOS]
Simanjuntak Yogy, Ko Hui-Ying, Lee Yi-Ling, Yu Guann-Yi, Lin Yi-Ling. Preventive effects of folic acid on Zika virus-associated poor pregnancy outcomes in immunocompromised mice. PLOS Pathogens. 16(5), e1008521, 2020. [JCR]　[WOS]
Chiu Chi-Fen, Chu Li-Wei, Liao I-Chen, Simanjuntak Yogy, Lin Yi-Ling, Juan Chi-Chang, Ping Yueh-Hsin. The Mechanism of the Zika Virus Crossing the Placental Barrier and the Blood-Brain Barrier. Frontiers in Microbiology. 11, 214, 2020. [JCR]　[WOS]
Fan YC, Liang JJ, Chen JM, Lin JW, Chen YY, Su KH, Lin CC, Tu WC, Chiou MT, Ou SC, Chang GJ, Lin YL, Chiou SS. NS2B/NS3 mutations enhance the infectivity of genotype I Japanese encephalitis virus in amplifying hosts. PLoS pathogens. 15(8), e1007992, 2019-08. [JCR]　[WOS]
Tung, Y.-T., J.-J. Liang, H.-T. Feng, R.-N. Jhang, S.-L. Hsieh, Y.-L. Lin, and G.-J. Wang. Investigation of the extremely weak interaction between the Japanese Encephalitis virus and CLEC5A using a multivalent-interaction- enhancement sensing electrode. Biosensors and Bioelectronics. 2, 100024, 2019-06. [JCR]
Yang CF, Gopula B, Liang JJ, Li JK, Chen SY, Lee YL, Chen CS, Lin YL. Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis. Emerging microbes & infections. 7(1), 187, 2018-11. [JCR]　[WOS]
Shen WF, Galula JU, Liu JH, Liao MY, Huang CH, Wang YC, Wu HC, Liang JJ, Lin YL, Whitney MT, Chang GJ, Chen SR, Wu SR, Chao DY. Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody. eLife. 7, e38970, 2018-10. [JCR]　[WOS]
Ko YA, Chan YH, Liu CH, Liang JJ, Chuang TH, Hsueh YP, Lin YL, Lin KI. Blimp-1-Mediated Pathway Promotes Type I IFN Production in Plasmacytoid Dendritic Cells by Targeting to Interleukin-1 Receptor-Associated Kinase M. Frontiers in Immunology. 9, 1828, 2018-08. [JCR]　[WOS]
Liang JJ, Chou MW, Lin YL. DC-SIGN Binding Contributed by an Extra N-Linked Glycosylation on Japanese Encephalitis Virus Envelope Protein Reduces the Ability of Viral Brain Invasion. Frontiers in Cellular and Infection Microbiology. 8, 239, 2018-07. [JCR]　[WOS]
Chiu HP, Chiu H, Yang CF, Lee YL, Chiu FL, Kuo HC, Lin RJ, Lin YL. Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein. PLoS Pathogens. 14(7), e1007166, 2018-07. [JCR]　[WOS]
Chan YL, Liao CL, Lin YL. Human Kinase/Phosphatase-Wide RNAi Screening Identified Checkpoint Kinase 2 as a Cellular Factor Facilitating Japanese Encephalitis Virus Infection. Frontiers in cellular and infection microbiology. 8, 142, 2018-05. [JCR]　[WOS]
Simanjuntak Y, Liang JJ, Chen SY, Li JK, Lee YL, Wu HC, Lin YL. Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission. PLoS Pathogens. 14(2), e1006854, 2018-02. [JCR]　[WOS]
Chen TH, Hu CC, Liao JT, Lee YL, Huang YW, Lin NS, Lin YL, Hsu YH. Production of Japanese Encephalitis Virus Antigens in Plants Using Bamboo Mosaic Virus-Based Vector. Frontiers in Microbiology. 8, 788, 2017-05. [JCR]　[WOS]
Simanjuntak Y, Liang JJ, Lee YL, Lin YL. Japanese Encephalitis Virus Exploits Dopamine D2 Receptor-phospholipase C to Target Dopaminergic Human Neuronal Cells. Frontiers in Microbiology. 8, 651, 2017-04. [JCR]　[WOS]
Lai JH, Lin YL, Hsieh SL. Pharmacological intervention for dengue virus infection. Biochemical Pharmacology. 129, 14-25, 2017-01. [JCR]　[WOS]
Tung YT, Chang CC, Lin YL, Hsieh SL, Wang GJ. Development of double-generation gold nanoparticle chip-based dengue virus detection system combining fluorescence turn-on probes. Biosensors & Bioelectronics. 77, 90-8, 2016-03. [JCR]　[WOS]
Yen LC, Liao JT, Lee HJ, Chou WY, Chen CW, Lin YL, Liao CL. The C Terminus of the Core beta-Ladder Domain in Japanese Encephalitis Virus Nonstructural Protein 1 Is Flexible for Accommodation of Heterologous Epitope Fusion. Journal of Virology. 90(3), 1178-89, 2016-02. [JCR]　[WOS]
Yu, C-Y.*, J.-J. Liang, J.-K. Li, Y.-L. Lee, B.-L. Chang, C.-I Su, W.-J. Huang, M. M. C. Lai and Y.-L. Lin*. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathogens. 11(12), e1005350, 2015-12. [JCR]　[WOS]
Simon-Loriere E, Lin RJ, Kalayanarooj SM, Chuansumrit A, Casademont I, Lin SY, Yu HP, Lert-Itthiporn W, Chaiyaratana W, Tangthawornchaikul N, Tangnararatchakit K, Vasanawathana S, Chang BL, Suriyaphol P, Yoksan S, Malasit P, Despres P, Paul R, Lin YL, Sakuntabhai A. High anti-dengue viral activity of the OAS gene family is associated with increased severity of dengue. The Journal of infectious diseases. 212: 2011-2020, 2015-12. [JCR]　[WOS]
Huang YT, Liao JT, Yen LC, Chang YK, Lin YL, Liao CL. Japanese encephalitis virus replicon-based vaccine expressing enterovirus-71 epitope confers dual protection from lethal challenges. Journal of biomedical science. 22(1), 74, 2015-09. [JCR]　[WOS]
Lin YC, Huang DY, Wang JS, Lin YL, Hsieh SL, Huang KC, Lin WW. Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization. Journal of leukocyte biology. 97(5), 825-835, 2015-05. [JCR]　[WOS]
Wang, L.-F., Y.-S. Lin, N.-C. Huang, C.-Y. Yu, W.-L. Tsai, J.-J. Chen, Toru Kubota, Mayumi Matsuoka, S.-R. Chen, C.-S. Yang, R.-W. Lu, Y.-L. Lin, and T.-H. Chang*. Hydroxychloroquine-inhibited dengue virus is associated with host defense machinery. Journal of Interferon & Cytokine Research. 35(3), 143-156, 2015-03. [JCR]　[WOS]
Kao, Y.-T., B.-L. Chang, J.-J. Liang, H.-J. Tsai, Y.-L. Lee, R.-J. Lin*, and Y.-L. Lin*. Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid b-oxidation. PLoS Pathogens. 11(3), e1004750, 2015-03. [JCR]　[WOS]
Simanjuntak, Y., J.-J. Liang, Y.-L. Lee, and Y.-L. Lin*. Repurposing of prochlorperazine for use against dengue virus infection. The Journal of Infectious Diseases. 211, 394-404, 2015-02. [JCR]　[WOS]
Lin, J.-C., S.-C. Lin, W.-Y. Chen, Y.-T. Yen, C.-W. Lai, M.-H. Tao, Y.-L. Lin, S.-C. Miaw, B. A. Wu-Hsieh*. Dengue viral protease interaction with NF-kB Inhibitor / results in endothelial cell apoptosis and hemorrhage development. Journal of Immunology. 193(4), 1258-1267, 2014-06. [JCR]　[WOS]
Tang, W.-C., R.-J. Lin, C.-L. Liao, and Y.-L. Lin*. Rab18 facilitates dengue virus infection by targeting fatty acid synthase to sites of viral replication. Journal of Virology. 88(12), 6793-6804, 2014-06. [JCR]　[WOS]
Liang, J.-J., J.-C. Wei, Y.-L. Lee, S.-H. Hsu*, J.-J. Lin, and Y.-L. Lin*. Surfactant-modified nanoclay exhibits an antiviral activity with high potency and broad spectrum. Journal of Virology. 88, 4218-4228, 2014-04. [JCR]　[WOS]
Lin, Y.-C., D.-Y. Huang, C.-L. Chu, Y.-L. Lin, and W.-W. Lin*. The tyrosine kinase Syk differentially regulates Toll-like receptor signaling downstream of the adaptor molecules TRAF6 and TRAF3. Science Signaling. 6(289), ra71, 2013-08. [JCR]　[WOS]
Yeh, H.-M., C.-Y. Yu, H.-C. Yang, S.-H. Ko, C.-L. Liao, and Y.-L. Lin*. Ubiquitin-specific protease 13 regulates IFN signaling by stabilizing STAT1. Journal of Immunology. 191(6), 3328-3336, 2013-08. [JCR]　[WOS]
Wu, M.-F., S.-T. Chen, A.-H. Yang, W.-W. Lin, Y.-L. Lin, N.-J. Chen, I-S. Tsai, L. Li, and S.-L. Hsieh*. CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages. Blood. 121(1), 95-106, 2013-01. [JCR]　[WOS]
Lin, R.-J.*, H.-L. Chien, S.-Y. Lin, B.-L. Chang, H.-P. Yu, W.-C. Tang, and Y.-L. Lin*. MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation. Nucleic Acids Research. 41(5), 3314-3326, 2013-01. [JCR]　[WOS]
Yen, L.-C., Y.-L. Lin, H.-H. Sung, J.-T. Liao, C.-H. Tsao, C.-M. Su, C.-K. Lin, and C.-L. Liao*. Neurovirulent flavivirus can be attenuated in mice by incorporation of neuron-specific microRNA recognition elements into viral genome. Vaccine. 31(49), 5915-5922, 2013. [JCR]　[WOS]
Wang, C.-Y., T.-H. Hsiao, L.-H. Chu, Y.-L. Lin, J.-L. Huang, C.-H. Chen*, and K. Peck*. Unraveling Virus Identity by Detection of Depleted Probes with Capillary Electrophoresis. Analytica Chimica Acta. 734, 88-92, 2012-11. [JCR]　[WOS]
Tu, Y.-C., C.-Y. Yu, J.-J. Liang, E. Lin, C.-L. Liao, and Y.-L. Lin*. Blocking double-stranded RNA-activated protein kinase PKR by Japanese encephalitis virus nonstructural protein 2A. Journal of Virology. 86, 10347-10358, 2012-10. [JCR]　[WOS]
Chang, T.-H.*, S.-R. Chen, C.-Y. Yu, Y.-S. Lin, Y.-S. Chen, T. Kubota, M. Matsuoka, and Y.-L. Lin*. Dengue virus serotype 2 blocks extracellular signal-regulated kinase and nuclear factor-B activation to downregulate cytokine production. PLoS One. 7(8), e41635, 2012-08. [JCR]　[WOS]
Yu, C.-Y., T.-H. Chang, J.-J. Liang, R.-L. Chiang, Y.-L. Lee, C.-L. Liao, and Y.-L. Lin. Dengue virus targets the adaptor protein MITA to subvert host innate immunity. PLoS Pathogens. 8(6): e1002780, 2012-06. [JCR]　[WOS]
Li, P.-C., M.-Y. Liao, P.-C. Cheng, J.-J. Liang, I-J. Liu, C.-Y. Chiu, Y.-L. Lin, G.-J. J. Chang, and H.-C. Wu. Development of a humanized antibody with high therapeutic potential against dengue virus type 2. PLoS Neglected Tropical Diseases. 6(5), e1636, 2012-05. [JCR]　[WOS]
Chen, S.-T., R.-S. Liu, M.-F. Wu, Y.-L. Lin, S.-Y. Chen, D. T.-W. Tan, T.-Y. Chou, I-S. Tsai, L. Li, and S.-L. Hsieh. CLEC5A regulates Japanese encephalitis virus-induced neuroinflammation and lethality. PLoS Pathogens. 8(4), e1002655, 2012-04. [JCR]　[WOS]
Li, J.-K., J.-J. Liang, C.-L. Liao, and Y.-L. Lin. Autophagy is involved in the early step of Japanese encephalitis virus infection. Microbes and Infection. 14, 159-168, 2012-02. [JCR]　[WOS]
Liang, J.-J., C.-Y. Yu, C.-L. Liao, and Y.-L. Lin. Vimentin binding is critical for infection by the virulent strain of Japanese encephalitis virus. Cellular Microbiology. 13, 1358-1370, 2011-09. [JCR]　[WOS]
Chien, H-L., C.-L. Liao, and Y.-L. Lin. The FUSE binding protein 1 interacts with untranslated regions of Japanese encephalitis virus RNA and negatively regulates viral replication. Journal of Virology. 85, 4698-4706, 2011-05. [JCR]　[WOS]
Chen ST, Lin YL, Huang MT, Wu MF, Hsieh SL. Targeting C-type lectin for the treatment of flavivirus infections. Advances in Experimental Medicine and Biology. 705, 769-776, 2011. [JCR]
Lin, K.-H., J.-J. Liang, W.-I Huang, S.-Y. Lin-Chu, C.-Y. Su, Y.-L. Lee, J.-T. Jan, Y.-L. Lin, Y.-S. E. Cheng, and C.-H. Wong. In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models. Antimicrobial Agents and Chemotherapy. 54(10), 4129-4136, 2010-10. [JCR]　[WOS]
Lee, T. C., Y.-L. Lin, J.-T. Liao, C.-M. Su, C.-C. Lin, W.-P. Lin, and C.-L. Liao. Utilizing liver-specific microRNA-122 to modulate replication of dengue virus replicon. Biochemical and Biophysical Research Communications. 396(3), 596-601, 2010-04. [JCR]　[WOS]
Yu, C.-Y., R.-L. Chiang, T.-H. Chang, C.-L. Liao, and Y.-L. Lin. The interferon stimulator mitochondrial antiviral signaling protein facilitates cell death by disrupting the mitochondrial membrane potential and by activating caspases. Journal of Virology. 84(5), 2421-2431, 2010-03. [JCR]　[WOS]
Lin, R.-J., H.-P. Yu, B.-L. Chang, W.-C. Tang, C.-L. Liao, and Y.-L. Lin. Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection. Journal of Immunology. 183(12), 8035-8043., 2009-12. [JCR]　[WOS]
Huang, T.-Y., H.-C. Chu, Y.-L. Lin, W.-H. Ho, H.-S. Hou, Y.-C. Chao, and C.-L. Liao. Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model. Biochemical and Biophysical Research Communications. 389: 634-639, 2009-11. [JCR]　[WOS]
Liang, J.-J., C.-L. Liao, J.-T. Liao, Y.-L. Lee, and Y.-L. Lin. A Japanese encephalitis virus vaccine candidate strain is attenuated by decreasing its interferon antagonistic ability. Vaccine. 27: 2746-2754, 2009-03. [JCR]　[WOS]
Huang, T.-Y., H.-C. Chu, Y.-L. Lin, C.-K. Lin, T.-Y. Hsieh, W.-K. Chang, Y.-C. Chao, and C.-L. Liao. Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinases. Toxicology and Applied Pharmacology. 237: 69-82, 2009-03. [JCR]　[WOS]
Chan, Y.-L., T.-H. Chang, C.-L. Liao, and Y.-L. Lin. The cellular antiviral protein Viperin is attenuated by proteasome-mediated protein degradation in Japanese encephalitis virus-infected cells. Journal of Virology. 82, 10455-10464, 2008-11. [JCR]　[WOS]
Tsao, C.-H., H.-L. Su, Y.-L. Lin, H.-P. Yu, S.-M. Kuo, C.-I. Shen, C.-W. Chen, and C.-L. Liao. Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner. Journal of General Virology. 89, 1930-1941, 2008-08. [JCR]　[WOS]
C. J. Lee, H. R. Lin, C. L. Liao and Y. L. Lin. Cholesterol effectively blocks entry of flavvirus infection. Journal of Virology. 82, 6470-6480, 2008-07. [JCR]　[WOS]
S. T. Chen, Y. L. Lin, M. T. Huang, M. F. Wu, S. C. Cheng, H. Y. Lei, C. K. Lee, T. W. Chiou, C. H. Wong and S. L. Hsieh. CLEC5A is critical for dengue-virus-induced lethal disease. Nature. 453, 672-676, 2008-05. [JCR]　[WOS]
C. Y. Yu, Y. W. Hsu, C. L. Liao and Y. L. Lin. Flavivirus infection activates XBP1 pathway of the unfolded protein response to cope with endoplasmic reticulum stress. Journal of Virology. 80, 11868-11880, 2006-12. [JCR]　[WOS]
Chen, J.-P.#, H.-L. Lu#, S.-L. Lai#, G.-S. Campanella, J.-M. Sung, M.-Y. Lu, B.-A. Wu-Hsieh, Y.-L. Lin, T.-E. Lane, A.-D. Luster, and F. Liao. Dengue virus induces expression of CXC chemokine ligand 10/IFN-gamma-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate. Journal of Immunology. 177, 3185-92, 2006-09. [JCR]　[WOS]
M. F. Hsieh, S. L. Lai, J. P. Chen, J. M. Sung, Y. L. Lin, B. A. Wu-Hsieh, C. Gerald, A. Luster and F. Liao. Both CXCR3 and CXCL10/IFN-Inducible Protein 10 Are Required for Resistance to Primary Infection by Dengue Virus. Journal of Immunology. 177, 1855-1863, 2006-08. [JCR]　[WOS]
R. J. Lin, B. L. Chang, H. P. Yu, C. L. Liao and Y. L. Lin. Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism. Journal of Virology. 80, 5908-5918, 2006-06. [JCR]　[WOS]
Chou, C.-C., T.-T. Lee, C.-H. Chen, H.-Y. Hsiao, Y.-L. Lin, M.-S. Ho, P.-C. Yang, and K. Peck. Design of microarray probes for virus identification and detection of emerging viruses at the genus level. BMC Bioinformatics. 7, 232, 2006-04. [JCR]　[WOS]
W. H. Liu, Y. L. Lin, J. P. Wang, W. Liou, R. F. Hou, Y. C. Wu and C. L. Liao. Restriction of vaccinia virus replication by a ced-3 and ced-4-dependent pathway in Caenorhabditis elegans. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 103, 4174-4179, 2006-03. [JCR]　[WOS]
T. H. Chang, C. L. Liao and Y. L. Lin. Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-kB activation. Microbes and Infection. 8, 157-171, 2006-01. [JCR]　[WOS]
P. H. Liang, W. C. Cheng, Y. L. Lee, H. P. Yu, Y. T. Wu, Y. L. Lin and C. H. Wong. Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis. ChemBioChem. 7, 165-173, 2006-01. [JCR]　[WOS]
C. J. Lee, C. L. Liao and Y. L. Lin. Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection. Journal of Virology. 79, 8388-8399, 2005-07. [JCR]　[WOS]
L. J. Ho, L. F. Hung, W. Y. Weng, W. L. Wu, P. Chou, Y. L. Lin, D. M. Chang, T. Y. Tai and J. H. Lai. Dengue virus type 2 antagonizes IFN-a but not IFN-r antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell. Journal of Immunology. 174, 8163-8172, 2005-06. [JCR]　[WOS]
C. T. Chen, Y. C. Yi, S. C. Chiang, K. C. Liu, Y. L. Lin and S. T. Lee. Selection of immunodominant fragments from envelope gene for vaccine against Japanese encephalitis virus in DNA priming-protein boosting protocols. Microbial Pathogenesis. 38, 53-62, 2005-02. [JCR]　[WOS]
Chu, H.-C., Y.-L. Lin, H.-K. Sytwu, S.-H. Lin, C.-L. Liao* and Y.-C. Chao.*. The effects of minocycline on Fas-mediated fulminant hepatitis in mice. British Journal of Pharmacology. 144, 275-282, 2005-01. [JCR]　[WOS]
Chen, T.-L., Y.-L. Lin, Y.-L. Lee, N.-S. Yang and M.-T. Chan.*. Expression of bioactive human interferon-gamma in transgenic rice cell suspension cultures. Transgenic Research. 13, 499-510, 2004-10. [JCR]　[WOS]
Lin, R.-J., C.-L. Liao, E. Lin and Y.-L. Lin.*. Blocking of alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection. Journal of Virology. 78, 9285-9294, 2004-09. [JCR]　[WOS]
R. J. Lin, C. L. Liao and Y. L. Lin. Replication-incompetent virions of Japanese encephalitis virus trigger neuronal cell death by oxidative stress in a culture system. Journal of General Virology. 85, 521-533, 2004-02. [JCR]　[WOS]
Wu, H.-H., C.-T. Chen, Y.-L. Lin and S.-T. Lee*. Sub-fragments of the envelope gene are highly protective against the Japanese encephalitis virus lethal infection in DNA priming-protein boosting immunization strategies. Vaccine. 22(5-6), 793-800, 2004-01. [JCR]　[WOS]
C. T. Chiou, C. C. Hu, P. H. Chen, C. L. Liao, Y. L. Lin and J. J. Wang. Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein. Journal of General Virology. 84, 2795-2805, 2003-10. [JCR]　[WOS]
S. P. Yang, L. J. Ho, Y. L. Lin, S. M. Cheng, T. P. Tsao, D. M. Chang, Y. L. Hsu, C. Y. Shih, T. Y. Juan and J. H. Lai. Carvedilol, a new antioxidative beta-blocker, blocks in vitro human peripheral blood T cell activation by downregulating NF-kappaB activity. Cardiovascular Research. 59, 776-787, 2003-09. [JCR]　[WOS]
S. F. Wu, C. L. Liao, Y. L. Lin, C. T. Yeh, L. K. Chen, Y. F. Huang, H. Y. Chou, J. L. Huang, M. F. Shaio and H. K. Sytwu. Evaluation of protective efficacy and immune mechanisms of using a non-structural protein NS1 in DNA vaccine against dengue 2 virus in mice. Vaccine. 21, 3919-3929, 2003-09. [JCR]　[WOS]
H. L. Su, C. L. Liao and Y. L. Lin. Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response. Journal of Virology. 76, 4162-4171, 2002-05. [JCR]　[WOS]
S. F. Wu, C. J. Lee, C. L. Liao, R. A. Dwek, N. Zitzmann and Y. L. Lin. Antiviral effects of an iminosugar derivative on flavivirus infections. Journal of Virology. 76, 3596-3604, 2002-04. [JCR]　[WOS]
J. L. Huang, J. H. Huang, R. H. Shyu, C. W. Teng, Y. L. Lin, M. D. Kuo, C. W. Yao and M. F. Shaio. High-level expression of recombinant dengue viral NS-1 protein and its potential use as a diagnostic antigen. J Med Virol. 65, 553-560, 2001-11. [JCR]　[WOS]
C. L. Liao, Y. L. Lin, B. C. Wu, C. H. Tsao, M. C. Wang, C. I. Liu, Y. L. Huang, J. H. Chen, J. P. Wang and L. K. Chen. Salicylates inhibit flavivirus replication independently of blocking nuclear factor kappa B activation. J Virol. 75, 7828-7839, 2001-09. [JCR]　[WOS]
C. M. Su, C. L. Liao, Y. L. Lee and Y. L. Lin. Highly sulfated forms of heparin sulfate are involved in japanese encephalitis virus infection. Virology. 286, 206-215, 2001-07. [JCR]　[WOS]
H. L. Su, Y. L. Lin, H. P. Yu, C. H. Tsao, L. K. Chen, Y. T. Liu and C. L. Liao. The effect of human bcl-2 and bcl-X genes on dengue virus-induced apoptosis in cultured cells. Virology. 282, 141-153, 2001-03. [JCR]　[WOS]
W. Chen, Y. Lin, C. Liao and S. Hsieh. Modulatory effects of the human heat shock protein 70 on DNA vaccination. J Biomed Sci. 7, 412-419, 2000-09. [JCR]　[WOS]
W. K. Wang, C. N. Lee, C. L. Kao, Y. L. Lin and C. C. King. Quantitative competitive reverse transcription-PCR for quantification of dengue virus RNA. J Clin Microbiol. 38, 3306-3310, 2000-09. [JCR]　[WOS]
H. W. Chen, C. H. Pan, M. Y. Liau, R. Jou, C. J. Tsai, H. J. Wu, Y. L. Lin and M. H. Tao. Screening of protective antigens of Japanese encephalitis virus by DNA immunization: a comparative study with conventional viral vaccines. J Virol. 73, 10137-10145, 1999-12. [JCR]　[WOS]
Y. S. Chang, C. L. Liao, C. H. Tsao, M. C. Chen, C. I. Liu, L. K. Chen and Y. L. Lin. Membrane permeabilization by small hydrophobic nonstructural proteins of Japanese encephalitis virus. J Virol. 73, 6257-6264, 1999-08. [JCR]　[WOS]
C. L. Liao, Y. L. Lin, S. C. Shen, J. Y. Shen, H. L. Su, Y. L. Huang, S. H. Ma, Y. C. Sun, K. P. Chen and L. K. Chen. Antiapoptotic but not antiviral function of human bcl-2 assists establishment of Japanese encephalitis virus persistence in cultured cells. J Virol. 72, 9844-9854, 1998-12. [JCR]　[WOS]
J. J. Wang, C. L. Liao, C. I. Yang, Y. L. Lin, C. T. Chiou and L. K. Chen. Localizations of NS3 and E proteins in mouse brain infected with mutant strain of Japanese encephalitis virus. Arch Virol. 143, 2353-2369, 1998-12. [JCR]　[WOS]
Y. L. Lin, C. L. Liao, L. K. Chen, C. T. Yeh, C. I. Liu, S. H. Ma, Y. Y. Huang, Y. L. Huang, C. L. Kao and C. C. King. Study of Dengue virus infection in SCID mice engrafted with human K562 cells. J Virol. 72, 9729-9737, 1998-12. [JCR]　[WOS]
Y. L. Lin, L. K. Chen, C. L. Liao, C. T. Yeh, S. H. Ma, J. L. Chen, Y. L. Huang, S. S. Chen and H. Y. Chiang. DNA immunization with Japanese encephalitis virus nonstructural protein NS1 elicits protective immunity in mice. J Virol. 72, 191-200, 1998-01. [JCR]　[WOS]
C. L. Liao, Y. L. Lin, J. J. Wang, Y. L. Huang, C. T. Yeh, S. H. Ma and L. K. Chen. Effect of enforced expression of human bcl-2 on Japanese encephalitis virus-induced apoptosis in cultured cells. J Virol. 71, 5963-5971, 1997-08. [JCR]　[WOS]
Y. L. Lin, Y. L. Huang, S. H. Ma, C. T. Yeh, S. Y. Chiou, L. K. Chen and C. L. Liao. Inhibition of Japanese encephalitis virus infection by nitric oxide: antiviral effect of nitric oxide on RNA virus replication. J Virol. 71, 5227-5235, 1997-07. [JCR]　[WOS]
Lin, Y.-L., C.-L. Liao, C.-T. Yeh, C.-H. Chang, Y.-L. Huang, Y.-Y. Huang, J.-T. Jan, C. Chin, and L.-K. Chen. A highly attenuated strain of Japanese encephalitis virus induces a protective immune response in mice. Virus Research. 44: 45-56, 1996. [JCR]　[WOS]
Chen, L.-K.*, Y.-L. Lin, C.-L. Liao, C.-G. Lin, Y.-L. Huang, C.-T. Yeh, S.-C. Lai, J.-T. Jan, and C. Chin. Generation and characterization of organ-tropism mutants of Japanese encephalitis virus in vivo and in vitro. Virology. 223: 79-88, 1996. [JCR]　[WOS]
Chen, L.-K.*, C.-L. Liao, C.-G. Lin, S.-C. Lai, C.-I. Liu, S.-H. Ma, Y.-Y. Huang, and Y.-L. Lin. Persistence of Japanese encephalitis virus is associated with abnormal expression of nonstructural protein NS1 in host cells. Virology. 217: 220-229, 1996. [JCR]　[WOS]
Selvakumar, R., L. A. Borenstein, Y.-L. Lin, R.Ahmed and F. O. Wettstein. Immunization with nonstructural proteins E1 and E2 of cottontail rabbit papillomavirus stimulates regression of virus-induced papillomas. Journal of Virology. 69: 602-605, 1995. [JCR]　[WOS]
Selvakumar, R., L. A. Borenstein, Y.-L. Lin, R. Ahmed and F. O. Wettstein. T cell response to cottontail rabbit papillomavirus structural proteins in infected rabbits. Journal of Virology. 68: 4043-4048, 1994. [JCR]　[WOS]
Lin, Y.-L., L. A. Borenstein, R. Ahmed and F. O. Wettstein. Cottontail rabbit papillomavirus L1 protein-based vaccines: Protection is achieved only with a full-length nondenatured product. Journal of Virology. 67: 4154-4162, 1993. [JCR]　[WOS]
Lin, Y.-L., L. A. Borenstein, R. Selvakumar, R. Ahmed and F. O. Wettstein. Progression from papilloma to carcinoma is accompanied by changes in antibody response to papillomavirus proteins. Journal of Virology. 67: 382-389, 1993. [JCR]　[WOS]
Lin, Y.-L., L. A. Borenstein, R. Selvakumar, R. Ahmed and F. O. Wettstein. Effective vaccination against papilloma development by immunization with L1 or L2 structural protein of cottontail rabbit papillomavirus. Virology. 187: 612-619, 1992. [JCR]　[WOS]
Meyers, C., J.-B. Harry, Y.-L. Lin, and F. O. Wettstein. Identification of three transforming proteins encoded by cottontail rabbit papillomavirus. Journal of Virology. 66(3),1655-1664, 1992. [JCR]　[WOS]

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