Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 楊泮池 Yang, Pan-Chyr

Journal 40

Hung PF, Hong TM, Chang CC, Hung CL, Hsu YL, Chang YL, Wu CT, Chang GC, Chan NL, Yu SL, Yang PC, Pan SH. Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis. Journal of experimental & clinical cancer research : CR. 38(1), 5, 2019. [JCR]　[WOS]
Tseng SJ, Kempson IM, Huang KY, Li HJ, Fa YC, Ho YC, Liao ZX, Yang PC. Targeting Tumor Microenvironment by Bioreduction-Activated Nanoparticles for Light-Triggered Virotherapy. ACS nano. 12(10), 9894-9902, 2018. [JCR]　[WOS]
Huang BT, Lai WY, Chang YC, Wang JW, Yeh SD, Lin EP, Yang PC. A CTLA-4 Antagonizing DNA Aptamer with Antitumor Effect. Molecular Therapy-Nucleic Acids. 8, 520-528, 2017. [JCR]　[WOS]
Lin CW, Wang LK, Wang SP, Chang YL, Wu YY, Chen HY, Hsiao TH, Lai WY, Lu HH, Chang YH, Yang SC, Lin MW, Chen CY, Hong TM, Yang PC. Corrigendum: Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1alpha/HDAC1/Slug axis. Nature communications. 8, 14502, 2017. [JCR]　[WOS]
Kao SH, Wang WL, Chen CY, Chang YL, Wu YY, Wang YT, Wang SP, Nesvizhskii AI, Chen YJ, Hong TM, Yang PC. GSK3beta controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug. Oncogene. 36(42), 5916, 2017. [JCR]　[WOS]
Wang YT, Pan SH, Tsai CF, Kuo TC, Hsu YL, Yen HY, Choong WK, Wu HY, Liao YC, Hong TM, Sung TY, Yang PC, Chen YJ. Phosphoproteomics Reveals HMGA1, a CK2 Substrate, as a Drug-Resistant Target in Non-Small Cell Lung Cancer. Scientific reports. 7, 44021, 2017. [JCR]　[WOS]
Lai WY, Huang BT, Wang JW, Lin PY, Yang PC. A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects. Molecular Therapy-Nucleic Acids. 5(12), e397, 2016. [JCR]　[WOS]
Wang LK, Pan SH, Chang YL, Hung PF, Kao SH, Wang WL, Lin CW, Yang SC, Liang CH, Wu CT, Hsiao TH, Hong TM, Yang PC. MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma. Oncotarget. 7(1), 386-401, 2016. [JCR]　[WOS]
Kuo TC, Li LW, Pan SH, Fang JM, Liu JH, Cheng TJ, Wang CJ, Hung PF, Chen HY, Hong TM, Hsu YL, Wong CH, Yang PC. Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin. Journal of medicinal chemistry. 59(18), 8521-34, 2016. [JCR]　[WOS]
Tseng SJ, Huang KY, Kempson IM, Kao SH, Liu MC, Yang SC, Liao ZX, Yang PC. Remote Control of Light-Triggered Virotherapy. ACS nano. 10(11), 10339-10346, 2016. [JCR]　[WOS]
Huang KY, Kao SH, Wang WL, Chen CY, Hsiao TH, Salunke SB, Chen JJ, Su KY, Yang SC, Hong TM, Chen CS, Yang PC. Small Molecule T315 Promotes Casitas B-Lineage Lymphoma-Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation. American journal of respiratory and critical care medicine. 193(7), 753-66, 2016. [JCR]　[WOS]
Tseng SJ, Liao ZX, Kao SH, Zeng YF, Huang KY, Li HJ, Yang CL, Deng YF, Huang CF, Yang SC, Yang PC, Kempson IM. Highly specific in vivo gene delivery for p53-mediated apoptosis and genetic photodynamic therapies of tumour. Nature communications. 6, 6456, 2015. [JCR]　[WOS]
Wang WL, Huang HC, Kao SH, Hsu YC, Wang YT, Li KC, Chen YJ, Yu SL, Wang SP, Hsiao TH, Yang PC, Hong TM. Slug is temporally regulated by cyclin E in cell cycle and controls genome stability. Oncogene. 34(9), 1116-25, 2015. [JCR]　[WOS]
Y. C. Chao, S. H. Pan, S. C. Yang, S. L. Yu, T. F. Che, C. W. Lin, M. S. Tsai, G. C. Chang, C. H. Wu, Y. Y. Wu, Y. C. Lee, T. M. Hong and P. C. Yang. Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma. American Journal of Respiratory and Critical Care Medicine. 179(2), 123-133, 2009. [JCR]　[WOS]
S. L. Yu, H. Y. Chen, G. C. Chang, C. Y. Chen, H. W. Chen, S. Singh, C. L. Cheng, C. J. Yu, Y. C. Lee, H. S. Chen, T. J. Su, C. C. Chiang, H. N. Li, Q. S. Hong, H. Y. Su, C. C. Chen, W. J. Chen, C. C. Liu, W. K. Chang, W. J. Chen, K. C. Li, J. J. W. Chen and P. C. Yang. Micro RNA signature predicts survival and relapase in lung cancer. Cancer Cell. 13(1), 48-57, 2008. [JCR]　[WOS]
C. C. Chou, H. Y. Hsiao, Q. S. Hong, C. H. Chen, Y. W. Peng, H. W. Chen and P. C. Yang. Single-walled carbon nanotubes can induce pulmonary injury in mouse model. Nano Lett. 8(2), 437-445, 2008. [JCR]　[WOS]
H. Y. Chen, S. L. Yu, C. H. Chen, G. C. Chang, C. Y. Chen, A. Yuan, C. L. Cheng, C. H. Wang, H. J. Terng, S. F. Kao, W. K. Chan, H. N. Li, C. C. Liu, S. Singh, W. J. Chen, J. J. W. Chen and P. C. Yang. A five-gene signature and clinical outcome in non-small-cell lung cancer. New Engl J Med. 356(1), 11-20, 2007. [JCR]　[WOS]
T. M. Hong, Y. L. Chen, Y. Y. Wu, A. Yuan, Y. C. Chao, Y. C. Chung, M. H. Wu, S. C. Yang, S. H. Pan, J. Y. Shih, W. K. Chan and P. C. Yang. Targeting neuropilin 1 as an antitumor strategy in lung cancer. Clin Cancer Res. 13, 4759-4768, 2007. [JCR]　[WOS]
M. F. Tsai, C. C. Wang, G. C. Chang, C. Y. Chen, H. Y. Chen, C. L. Cheng, Y. P. Yang, C. Y. Wu, F. Y. Shih, C. C. Liu, H. P. Lin, Y. S. Jou, S. C. Lin, C. W. Lin, W. J. Chen, W. K. Chan, J. J. W. Chen and P. C. Yang. A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma. Journal of the National Cancer Institute. 98(12), 825-838, 2006. [JCR]　[WOS]
C. C. Chou, T. T. Lee, C. H. Chen, H. Y. Hsiao, Y. L. Lin, M. S. Ho, P. C. Yang and K. Peck. Design of microarray probes for virus identification and detection of emerging viruses at the genus level. BMC Bioinformatics. 7, 232, 2006. [JCR]　[WOS]
Y. P. Sher, C. C. Chou, R. H. Chou, H. M. Wu, W. S. W. Chang, C. H. Chen, P. C. Yang, C. W. Wu, C. L. Yu and K. Peck. Human kallikrein 8 protease confers a favorable clinical outcome in non-small cell lung cancer by suppressing tumor cell invasiveness. Cancer Res. 66, 11763-11770, 2006. [JCR]　[WOS]
Y. W. Chang, S. C. Chen, E. C. Cheng, Y. P. Ko, Y. C. Lin, Y. R. Kao, Y. G. Tsay, P. C. Yang, C. W. Wu and S. R. Roffler. CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells. Int J Cancer. 116(2), 243-252, 2005. [JCR]　[WOS]
Y. P. Sher, J. Y. Shih, P. C. Yang, S. R. Roffler, Y. W. Chu, C. W. Wu, C. L. Yu and K. Peck. Prognosis of non-small cell lung cancer patients by detecting circulating cancer cells in the peripheral blood with multiple marker genes. Clin Cancer Res. 11, 173-179, 2005. [JCR]　[WOS]
S. L. Yu, H. W. Chen, P. C. Yang, K. Peck, M. H. Tsai, J. J. W. Chen and F. Y. Lin. Differential gene expression in gram-negative and gram-positive sepsis. American Journal of Respiratory and Critical Care Medicine. 169(10), 1135-1143, 2004. [JCR]　[WOS]
H. W. Chen, S. L. Yu, W. J. Chen, P. C. Yang, C. T. Chien, H. Y. Chou, H. N. Li, K. Peck, C. H. Huang, F. Y. Lin, J. J. W. Chen and Y. T. Lee. Dynamic changes of gene expression profiles during postnatal heart development in mice. Heart. 90(8), 927-934, 2004. [JCR]　[WOS]
Y. R. Kao, J. Y. Shih, W. C. Wen, Y. P. Ko, B. M. Chen, Y. L. Chan, Y. W. Chu, P. C. Yang, C. W. Wu and S. R. Roffler. Tumor-associated antigen L6 and the invasion of human lung cancer cells. Clin Cancer Res. 9, 2807-2816, 2003. [JCR]　[WOS]
A. Yuan, C. J. Yu, K. T. Luh, S. H. Kuo, Y. C. Lee and P. C. Yang. Aberrant p53 expression correlates with expression of vascular endothelial growth factor mRNA and interleukin-8 mRNA and neoangiogenesis in non-small-cell lung cancer. J Clin Oncol. 20, 900-910, 2002. [JCR]　[WOS]
C. J. Yu, J. Y. Shew, Y. S. Liaw, S. H. Kuo, K. T. Luh and P. C. Yang. Application of mucin quantitative competitive reverse transcription polymerase chain reaction in assisting the diagnosis of malignant pleural effusion. American Journal of Respiratory and Critical Care Medicine. 164, 1312-1318, 2001. [JCR]　[WOS]
J. Y. Shih, S. C. Yang, T. M. Hong, A. Yuan, J. J. Chen, C. J. Yu, Y. L. Chang, Y. C. Lee, K. Peck, C. W. Wu and P. C. Yang. Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells. Journal of the National Cancer Institute. 93, 1392-1400, 2001. [JCR]　[WOS]
J. J. Chen, K. Peck, T. M. Hong, S. C. Yang, Y. P. Sher, J. Y. Shih, R. Wu, J. L. Cheng, S. R. Roffler, C. W. Wu and P. C. Yang. Global analysis of gene expression in invasion by a lung cancer model. Cancer Res. 61, 5223-5230, 2001. [JCR]　[WOS]
T. M. Hong, J. J. Chen, K. Peck, P. C. Yang and C. W. Wu. p53 amino acids 339-346 represent the minimal p53 repression domain. J Biol Chem. 276, 1510-1515, 2001. [JCR]　[WOS]
A. Yuan, C. J. Yu, S. H. Kuo, W. J. Chen, F. Y. Lin, K. T. Luh, P. C. Yang and Y. C. Lee. Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer. Journal of Clinical Oncology. 19(2), 432-441, 2001. [JCR]　[WOS]
A. Yuan, C. J. Yu, W. J. Chen, F. Y. Lin, S. H. Kuo, K. T. Luh and P. C. Yang. Correlation of total VEGF mRNA and protein expression with histologic type, tumor angiogenesis, patient survival and timing of relapse in non-small-cell lung cancer. International Journal of Cancer. 89, 475-483, 2000. [JCR]　[WOS]
T. M. Hong, P. C. Yang, K. Peck, J. J. Chen, S. C. Yang, Y. C. Chen and C. W. Wu. Profiling the downstream genes of tumor suppressor PTEN in lung cancer cells by complementary DNA microarray. American Journal of Respiratory Cell and Molecular Biology. 23(3), 355-363, 2000. [JCR]　[WOS]
K. Peck, Y. P. Sher, J. Y. Shih, S. R. Roffler, C. W. Wu and P. C. Yang. Detection and quantitation of circulating cancer cells in the peripheral blood of lung cancer patients. Cancer Res. 58, 2761-2765, 1998. [JCR]　[WOS]
C. J. Lin, P. C. Yang, M. T. Hsu, F. H. Yew, T. Y. Liu, C. T. Shun, S. W. Tyan and T. C. Lee. Induction of pulmonary fibrosis in organ-cultured rat lung by cadmium chloride and transforming growth factor-beta1. Toxicology. 127, 157-166, 1998. [JCR]　[WOS]
K. Peck, P. C. Yang and S. L. Wung. Methods for rapid antimicrobial susceptibility testing. US Patent. #5,789,173, 1998.
J. J. Chen, R. Wu, P. C. Yang, J. Y. Huang, Y. P. Sher, M. H. Han, W. C. Kao, P. J. Lee, T. F. Chiu, F. Chang, Y. W. Chu, C. W. Wu and K. Peck. Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection. Genomics. 51, 313-324, 1998. [JCR]　[WOS]
Y. W. Chu, P. C. Yang, S. C. Yang, Y. C. Shyu, M. J. Hendrix, R. Wu and C. W. Wu. Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line. American Journal of Respiratory Cell and Molecular Biology. 17, 353-360, 1997. [JCR]　[WOS]
A. Yuan, P. C. Yang, C. J. Yu, Y. C. Lee, Y. T. Yao, C. L. Chen, L. N. Lee, S. H. Kuo and K. T. Luh. Tumor angiogenesis correlates with histologic type and metastasis in non-small-cell lung cancer. American Journal of Respiratory and Critical Care Medicine. 152, 2157-2162, 1995. [JCR]　[WOS]

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