Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 周玉山 Jou, Yuh-Shan

Journal 87

Chen KJ, Huang JH, Shih JH, Gu DL, Lee SS, Shen R, Hsu YH, Kung YC, Wu CY, Ho CM, Jen HW, Lee HY, Lang YD, Hsiao CH, Jou YS. Somatic A-to-I RNA-edited RHOA isoform 2 specific-R176G mutation promotes tumor progression in lung adenocarcinoma. Molecular carcinogenesis. , 2023. [JCR]　[WOS]
Wang YW, Chen SC, Gu DL, Yeh YC, Tsai JJ, Yang KT, Jou YS, Chou TY, Tang TK. A novel HIF1alpha-STIL-FOXM1 axis regulates tumor metastasis. Journal of biomedical science. 29(1), 24, 2022. [JCR]　[WOS]
Chen HY, Chan SJ, Liu X, Wei AC, Jian RI, Huang KW, Lang YD, Shih JH, Liao CC, Luan CL, Kao YT, Chiang SY, Hsiao PW, Jou YS, Chen Y, Chen RH. Long noncoding RNA Smyca coactivates TGF-beta/Smad and Myc pathways to drive tumor progression. Journal of hematology & oncology. 15(1), 85, 2022. [JCR]　[WOS]
Ho CM, Lin KT, Shen R, Gu DL, Lee SS, Su WH, Jou YS. Prognostic comparative genes predict targets for sorafenib combination therapies in hepatocellular carcinoma. Computational and structural biotechnology journal. 20, 1752-1763, 2022. [JCR]　[WOS]
Lang YD, Jou YS. PSPC1 is a new contextual determinant of aberrant subcellular translocation of oncogenes in tumor progression. Journal of biomedical science. 28(1), 57, 2021. [JCR]　[WOS]
Jen Hsin-Wei, Gu De-Leung, Lang Yaw-Dong, Jou Yuh-Shan. PSPC1 Potentiates IGF1R Expression to Augment Cell Adhesion and Motility. Cells. 9(6), 1490, 2020-06. [JCR]　[WOS]
Shih JH, Chen HY, Lin SC, Yeh YC, Shen R, Lang YD, Wu DC, Chen CY, Chen RH, Chou TY, Jou YS*. Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma. Nucleic acids research. 48(3),1175-1191, 2020-02. [JCR]　[WOS]
Lang Yaw-Dong, Jou Yuh-Shan. PSPC1: a contextual determinant of tumor progression. Molecular & Cellular Oncology. 7(2), 1721253, 2020-02.　[WOS]
Lang YD, Chen HY, Ho CM, Shih JH, Hsu EC, Shen R, Lee YC, Chen JW, Wu CY, Yeh HW, Chen RH, Jou YS*. PSPC1-interchanged interactions with PTK6 and beta-catenin synergize oncogenic subcellular translocations and tumor progression. Nature communications. 10(1), 5716, 2019-12. [JCR]　[WOS]
Yeh HW, Lee SS, Chang CY, Lang YD, Jou YS*. A New Switch for TGFbeta in Cancer. Cancer research. 79(15), 3797-3805, 2019-08. [JCR]　[WOS]
Yang CF, Chen YY, Singh JP, Hsu SF, Liu YW, Yang CY, Chang CW, Chen SN, Shih RH, Hsu SD, Jou YS, Cheng CF, Meng TC. Targeting protein tyrosine phosphatase PTP-PEST (PTPN12) for therapeutic intervention in acute myocardial infarction. Cardiovascular research. 116(5), 1032-1046, 2019-04. [JCR]　[WOS]
Lee HY, Chen CK, Ho CM, Lee SS, Chang CY, Chen KJ, Jou YS*. EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma. Oncotarget. 9(17), 13193-13205, 2018. [JCR]
Su WH, Jou YS, Zhang JH, Ho CM, Tai DI. Mutations in NOTCH1 and nucleotide excision repair genes are correlated with prognosis of hepatitis B virus-associated hepatocellular carcinoma. Journal of Cancer. 9(15), 2678-2686, 2018. [JCR]　[WOS]
Yeh HW, Hsu EC, Lee SS, Lang YD, Lin YC, Chang CY, Lee SY, Gu DL, Shih JH, Ho CM, Chen CF, Chen CT, Tu PH, Cheng CF, Chen RH, Yang RB, Jou YS*. PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis. Nature cell biology. 20(4), 479-491, 2018. [JCR]　[WOS]
Yeh HW, Jou YS*. PSPC1 potentiates TGF-beta-dependent metastatic dissemination. Molecular & cellular oncology. 5(4), e1472058, 2018. [JCR]　[WOS]
Shen ZQ, Chen YF, Chen JR, Jou YS, Wu PC, Kao CH, Wang CH, Huang YL, Chen CF, Huang TS, Shyu YC, Tsai SF, Kao LS, Tsai TF. CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular Carcinoma. Cell reports. 21(8), 2198-2211, 2017. [JCR]　[WOS]
Hua K, Lin CH, Chen YL, Lin CH, Ping YH, Jou YS, Chen CF. Identification of novel cancer fusion genes using chromosome breakpoint screening. Oncology reports. 37(4), 2101-2108, 2017. [JCR]　[WOS]
Yeh HW, Lee SS, Chang CY, Hu CM, Jou YS*. Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis. Oncotarget. 8(44), 77734-77751, 2017. [JCR]　[WOS]
Lin CH, Lin YW, Chen YC, Liao CC, Jou YS, Hsu MT, Chen CF. FNDC3B promotes cell migration and tumor metastasis in hepatocellular carcinoma. Oncotarget. 7(31), 49498-49508, 2016. [JCR]　[WOS]
Chang YC, Chiu YF, He CT, Sheu WH, Lin MW, Seto TB, Assimes T, Jou YS, Su L, Lee WJ, Lee PC, Tsai SH, Chuang LM. Genome-wide linkage analysis and regional fine mapping identified variants in the RYR3 gene as a novel quantitative trait locus for circulating adiponectin in Chinese population. Medicine. 95(44), e5174, 2016. [JCR]　[WOS]
Hsiao YJ, Su KY, Hsu YC, Chang GC, Chen JS, Chen HY, Hong QS, Hsu SC, Kang PH, Hsu CY, Ho BC, Yang TH, Wang CY, Jou YS, Yang PC, Yu SL. SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma. Oncotarget. 7(28), 44417-44429, 2016. [JCR]　[WOS]
Huang YS, Chang CC, Lee SS, Jou YS, Shih HM. Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression. Oncotarget. 7(28), 43256-43266, 2016. [JCR]　[WOS]
Chang TJ, Chiu YF, Sheu WH, Shih KC, Hwu CM, Quertermous T, Jou YS, Kuo SS, Chang YC, Chuang LM. Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population. Scientific reports. 5, 14380, 2015. [JCR]　[WOS]
Sudhir PR, Lin ST, Chia-Wen C, Yang SH, Li AF, Lai RH, Wang MJ, Chen YT, Chen CF, Jou YS, Chen JY. Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence. Scientific reports. 5, 9633, 2015. [JCR]　[WOS]
Chung CM, Wang RY, Fann CS, Chen JW, Jong YS, Jou YS, Yang HC, Kang CS, Chen CC, Chang HC, Pan WH. Fine-mapping angiotensin-converting enzyme gene: separate QTLs identified for hypertension and for ACE activity. PloS one. 8(3), e56119, 2013. [JCR]　[WOS]
Wang YW, Lin KT, Chen SC, Gu DL, Chen CF, Tu PH, Jou YS*. Overexpressed-eIF3I interacted and activated oncogenic Akt1 is a theranostic target in human hepatocellular carcinoma. HEPATOLOGY. 58(1), 239-250, 2013. [JCR]　[WOS]
Gu DL, Chen YH, Shih JH, Lin CH, Jou YS, Chen CF. Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma. World journal of gastroenterology : WJG. 19(47), 8873-9, 2013. [JCR]　[WOS]
Hung PF, Hong TM, Hsu YC, Chen HY, Chang YL, Wu CT, Chang GC, Jou YS, Pan SH, Yang PC. The motor protein KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinoma. PloS one. 8(4), e61664, 2013. [JCR]　[WOS]
Lin KT, Wang YW, Chen CT, Ho CM, Su WH, Jou YS. HDAC inhibitors augmented cell migration and metastasis through induction of PKCs leading to identification of low toxicity modalities for combination cancer therapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 18(17), 4691-701, 2012. [JCR]　[WOS]
Kao S, Shiau CK, Gu DL, Ho CM, Su WH, Chen CF, Lin CH, Jou YS. IGDB.NSCLC: integrated genomic database of non-small cell lung cancer. Nucleic acids research. 40(Database issue), D972-7, 2012. [JCR]　[WOS]
Chang CY, Lin SC, Su WH, Ho CM, Jou YS. Somatic LMCD1 mutations promoted cell migration and tumor metastasis in hepatocellular carcinoma. Oncogene. 31, 2640–2652, 2012. [JCR]　[WOS]
Lin JC, Wu YY, Wu JY, Lin TC, Wu CT, Chang YL, Jou YS, Hong TM, Yang PC. TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma. EMBO molecular medicine. 4(6), 472-85, 2012. [JCR]　[WOS]
Yuan WC, Lee YR, Huang SF, Lin YM, Chen TY, Chung HC, Tsai CH, Chen HY, Chiang CT, Lai CK, Lu LT, Chen CH, Gu DL, Pu YS, Jou YS, Lu KP, Hsiao PW, Shih HM, Chen RH. A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression. Cancer cell. 20(2), 214-228, 2011. [JCR]　[WOS]
Chien HT, Liao CT, Huang SF, Chen IH, Liu TY, Jou YS, Wang HM, Hsieh LL. Clinical significance of genome-wide minimally deleted regions in oral squamous cell carcinomas. GENES CHROMOSOMES & CANCER. 50(5), 358-369, 2011. [JCR]　[WOS]
Wang YW, Tu PH, Lin KT, Lin SC, Ko JY, Jou YS. Identification of oncogenic point mutations and hyperphosphorylation of anaplastic lymphoma kinase in lung cancer. NEOPLASIA. 13(8), 704-715, 2011. [JCR]　[WOS]
Shiau CK, Gu DL, Chen CF, Lin CH, Jou YS. IGRhCellID: integrated genomic resources of human cell lines for identification. Nucleic acids research. 39(Database issue), D520-4, 2011. [JCR]　[WOS]
Lo YL, Hsiao CF, Jou YS, Chang GC, Tsai YH, Su WC, Chen KY, Chen YM, Huang MS, Hsieh WS, Chen CJ, Hsiung CA. Polymorphisms of MLH1 and MSH2 genes and the risk of lung cancer among never smokers. LUNG CANCER. 72(3), 280-286, 2011. [JCR]　[WOS]
Li SC, Chan WC, Lai CH, Tsai KW, Hsu CN, Jou YS, Chen HC, Chen CH, Lin WC. UMARS: Un-MAppable Reads Solution. BMC bioinformatics. 12 Suppl 1, S9, 2011. [JCR]　[WOS]
Lo YL, Hsiao CF, Jou YS, Chang GC, Tsai YH, Su WC, Chen YM, Huang MS, Chen HL, Yang PC, Chen CJ, Hsiung CA. ATM polymorphisms and risk of lung cancer among never smokers. LUNG CANCER. 69(2), 148-54, 2010. [JCR]　[WOS]
Chang YC, Chiu YF, Shih KC, Lin MW, Sheu WH, Donlon T, Curb JD, Jou YS, Chang TJ, Li HY, Chuang LM. Common PCSK1 haplotypes are associated with obesity in the Chinese population. OBESITY. 18(7), 1404-9, 2010. [JCR]　[WOS]
Chen CF, Hsu EC, Lin KT, Tu PH, Chang HW, Lin CH, Chen YJ, Gu DL, Lin CH, Wu JY, Chen YT, Hsu MT, Jou YS. Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. HEPATOLOGY. 52(5), 1690-701, 2010. [JCR]　[WOS]
Lai RH, Hsiao YW, Wang MJ, Lin HY, Wu CW, Chi CW, Li AF, Jou YS, Chen JY. SOCS6, down-regulated in gastric cancer, inhibits cell proliferation and colony formation. Cancer letters. 288(1), 75-85, 2010. [JCR]　[WOS]
Y. L. Lo, Y. S. Jou, C. F. Hsiao, G. C. Chang, Y. H. Tsai, W. C. Su, K. Y. Chen, Y. M. Chen, M. S. Huang, C. Y. Hu, C. J. Chen and C. A. Hsiung. A polymorphism in the APE1 gene promoter is associated with lung cancer risk. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. 18(1), 223-229, 2009. [JCR]　[WOS]
Y. S. Jou, Y. L. Lo, C. F. Hsiao, G. C. Chang, Y. H. Tsai, W. C. Su, Y. M. Chen, M. S. Huang, H. L. Chen, C. J. Chen, P. C. Yang and C. A. Hsiung. Association of an EGFR intron 1 SNP with never-smoking female lung adenocarcinoma patients. Lung Cancer. 64(3):251-6, 2009. [JCR]　[WOS]
Lin SH, Liu CM, Liu YL, Shen-Jang Fann C, Hsiao PC, Wu JY, Hung SI, Chen CH, Wu HM, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Chang CC, Yang WC, Lin JJ, Chou FH, Faraone SV, Tsuang MT, Hwu HG, Chen WJ. Clustering by neurocognition for fine mapping of the schizophrenia susceptibility loci on chromosome 6p. Genes Brain Behav. 8(8), 785-794, 2009. [JCR]　[WOS]
P. Chen, Y. S. Jou, C. S. J. Fann, J. W. Chen,, C. M. Chung, C. Y. Lin, S. Y. Wu, M. J. Kang, Y. C. Chen, Y. S. Jong, M. H. Lo, C. S. Kang, C. C. Chen, H. C. Chang, N. K. Huang, Y. L. Wu and W. H. Pan. Lipoprotein lipase variants associated with an endophenotype of hypertension: hypertension combined with elevated triglycerides. Hum Mutat. 30(1), 49-55, 2009. [JCR]　[WOS]
Tseng MY, Liu SY, Chen HR, Wu YJ, Chiu CC, Chan PT, Chiang WF, Liu YC, Lu CY, Jou YS, Chen JY. Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma. Oral oncology. 45(9), 771-776, 2009. [JCR]　[WOS]
W. L. Ma, C. L. Hsu, M. H. Wu, C. T. Wu, C. C. Wu, J. J. Lai, Y. S. Jou, C. W. Chen, S. Yeh and C. Chang. Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma. Gastroenterology. 135(3), 947-955, 2008. [JCR]　[WOS]
H. H. Chen, Y. S. Jou, W. J. Lee and W. H. Pan. Applying polynomial standard curve method to correct bias encountered in estimating allele DNA pooling strategy. Genomics. 92(6), 429-435, 2008. [JCR]　[WOS]
R. Y. Wang, C. M. Chung, C. S. Fann, H. C. Yang, J. W. Chen, Y. S. Jong, Y. S. Jou, H. M. Lo, F. M. Ho, C. S. Kang, C. C. Chen, H. C. Chang, S. K. Shyue and W. H. Pan. Genome-wide scan for quantitative ACE activity in Taiwan young-onset hypertension study. Hum Hered. 65, 85-90, 2008. [JCR]　[WOS]
S. Y. Liu, Y. T. Chen, M. Y. Tseng, C. C. Hung, W. F. Chiang, H. R. Chen, T. Y. Shieh, C. H. Chen, Y. S. Jou and J. Y. Chen. Involvement of microtubule-associated protein (MAP2) in oral cancer cell motility: a novel biological function of MAP2 in non-neuronal cell. Biochemical and Biophysical Research Communications. 366(2), 520-525, 2008. [JCR]　[WOS]
Y. L. Liu, C. S. J. Fann, C. M. Liu, W. J. Chen, J. Y. Wu, S. I. Hung, C. H. Chen, Y. S. Jou, S. K. Liu, T. J. Hwang, M. H. Hsieh, C. C. Chang, W. C. Yang, J. J. Lin, F. H. Chou, S. V. Faraone, M. T. Tsuang and H. G. Hwu. RASD2, MYH9m and CACNG2 genes at chromosome 22q12 associated with the subgroup of schizophrenia with non-deficit in sustained attention and executive function. Biol Psychiatry. 64(9), 789-796, 2008. [JCR]　[WOS]
J. Y. F. Chen, C. C. Hung, K. L. Huang, Y. T. Chen, S. Y. Liu, W. F. Chiang, H. R. Chen, C. Y. Yen, Y. J. Wu, J. Y. Ko and Y. S. Jou. Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma. Neoplasia. 10(12), 1393-1401, 2008. [JCR]　[WOS]
C. M. Liu, Y. L. Liu, C. S. J. Fann, W. J. Chen, W. C. Yang, W. C. Ouyang, C. Y. Chen, Y. S. Jou, M. H. Hsieh, S. K. Liu, T. J. Hwang, S. V. Faraone, M. T. Tsuang, and H. G. Hwu. Association evidence of schizophrenia with distal genomic region of NOTCH4 in Taiwanese families. Genes Brain Behav. 6(6), 497-502, 2007. [JCR]　[WOS]
Y. L. Chang, C. T. Wu, S. C. Lin, C. F. Hsiao, Y. S. Jou and Y. C. Lee. Clonality and prognostic implications of p53 and epidermal growth factor receptor somatic aberrations in multiple primary lung cancers. Clin Cancer Res. 13(1), 52-58, 2007. [JCR]　[WOS]
P. K. Sen, M.T. Tsai, and Y. S. Jou. High Dimension Low Sample Size Perspectives in Constrained Statistical Inference: The SARSCoV RNA Genome in Illustration. Journal of the American Statistical Association. 102, 686-694, 2007. [JCR]　[WOS]
Y. L. Liu, C. S. Fann, C. M. Liu, C. C. Chang, W. C. Yang, S. I. Hung, S. L. Yu, T. J. Hwang, M. H. Hsieh, C. C. Liu, M. M. Tsuang, J. Y. Wu, Y. S. Jou, S. V. Faraone, M. T. Tsuang, W. J. Chen and H. G. Hwu. More evidence supports the association of PPP3CC with schizophrenia. Mol Psychiatry. 12(10), 966-974, 2007. [JCR]　[WOS]
W. H. Su, C. C. Chao, S. H. Yeh, D. S. Chen, P. J. Chen and Y. S. Jou. OncoDB.HCC: an integrated oncogenomic database of hepatocellular carcinoma revealed aberrant cancer target genes and loci. Nucleic Acids Res. 35, D727-731, 2007. [JCR]　[WOS]
M. F. Tsai, C. C. Wang, G. C. Chang, C. Y. Chen, H. Y. Chen, C. L. Cheng, Y. P. Yang, C. Y. Wu, F. Y. Shih, C. C. Liu, H. P. Lin, Y. S. Jou, S. C. Lin, C. W. Lin, W. J. Chen, W. K. Chan, J.J.W. Chen and P. C. Yang. A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma. JNCI-Journal of the National Cancer Institute. 98(12), 825-838, 2006. [JCR]　[WOS]
Y. L. Liu, C. S. J. Fann, C. M. Liu, W. J. Chen, J. Y. Wu, S. I. Hung, C. H. Chen, Y. S. Jou, S. K. Liu, T. J. Hwang, M. H. Hsieh, W. C. Ouyang, H. Y. Chan, J. J. Chen, W. C. Yang, C. Y. Lin, S. F. C. Lee and H. G. Hwu. A Single Nucleotide Polymorphism Fine Mapping Study of Chromosome 1q42.1 Reveals the Vulnerability Genes for Schizophrenia, GNPAT and DISC1: Association with Impairment of Sustained Attention. Biol Psychiatry. 60(6), 554-562, 2006. [JCR]　[WOS]
K. T. Lin, S. H. Yeh, D. S. Chen, P. J. Chen and Y. S. Jou. Epigenetic activation of alpha4, beta2 and beta6 integrins involved incell migration in trichostatin A-treated Hep3B cells. J Biomed Sci. 12, 803-813, 2005. [JCR]　[WOS]
R. C. Tseng, J. W. Chang, F. J. Hsien, Y. H. Chang, C. F. Hsiao, J. T. Chen, C. Y. Chen, Y. S. Jou and Y. C. Wang. Genomewide loss of heterozygosity and its clinical associations in nonsmall cell lung cancer. Int J Cancer. 117, 241-247, 2005. [JCR]　[WOS]
P. Chen, Y. S. Jou, C. S. Fann, J. W. Chen, S. Y. Wu and W. H. Pan. Lipoprotein Lipase Gene is Linked and Associated with Hypertension inTaiwan Young-onset Hypertension Genetic Study. J Biomed Sci. 12, 651-658, 2005. [JCR]　[WOS]
C. F. Chen, S. H. Yeh, D. S. Chen, P. J. Chen and Y. S. Jou. Molecular genetic evidence supporting a novel human hepatocellularcarcinoma tumor suppressor locus at 13q12.11. Genes Chromosomes Cancer. 44, 320-328, 2005. [JCR]　[WOS]
Y. H. Chang, W. H. Su, T. C. Lee, H. F. Sun, C. H. Chen, W. H. Pan, S. F. Tsai and Y. S. Jou. TPMD: a database and resources of microsatellite marker genotyped in Taiwanese populations. Nucleic Acids Res. 33, D174-D177, 2005. [JCR]　[WOS]
Y. F. Liu, W. M. Chen, Y. F. Lin, R. C. Yang, M. W. Lin, L. H. Li, Y. H. Chang, Y. S. Jou, P. Y. Lin, J. S. Su, S. F. Huang, K. J. Hsiao, C.S.J. Fann, H. W. Hwang, Y. T. Chen and S. F. Tsai. Type II collagen gene variants and inherited osteonecrosis of the femoral head. NEW ENGLAND JOURNAL OF MEDICINE. 352, 2294-2301, 2005. [JCR]　[WOS]
W. M. Chen, Y. F. Liu, M. W. Lin, I. C. Chen, P. Y. Lin, G. L. Lin, Y. S. Jou, Y. T. Lin, C. S. J. Fann, J. Y. Wu, K. J. Hsiao and S. F. Tsai. Autosomal dominant avascular necrosis of femoral head in two Taiwanese pedigrees and linkage to chromosome 12q13. Am J Hum Genet. 75, 310-317, 2004. [JCR]　[WOS]
Y. S. Jou, C. S. Lee, Y. H. Chang, C. F. Hsiao, C. F. Chen, C. C. Chao, L. S. Wu, S. H. Yeh, D. S. Chen and P. J. Chen. Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma. Cancer Res. 64, 3030-3036, 2004. [JCR]　[WOS]
J. S. Huang, C. C. Chao, T. L. Su, S. H. Yeh, D. S. Chen, C. T. Chen, P. J. Chen and Y. S. Jou. Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma. Biochemical and Biophysical Research Communications. 315(4), 950-958, 2004. [JCR]　[WOS]
Y. C. Lee, C. T. Wu, J. Y. Shih, Y. S. Jou and Y. L. Chang. Frequent allelic deletion at the FHIT locus associated with p53 overexpression in squamous cell carcinoma subtype of Taiwanese non-small-cell lung cancers. BRITISH JOURNAL OF CANCER. 90, 2378-2383, 2004. [JCR]　[WOS]
J. Y. Chen, Y. L. Chang, Y. C. Yu, C. C. Chao, H. W. Kao, C. T. Wu, W. C. Lin, J. Y. Ko and Y. S. Jou. Specific induction of the high-molecular-weight microtubule-associated protein 2 (hmw-MAP2) by betel quid extract in cultured oral keratinocytes: clinical implications in betel quid-associated oral squamous cell carcinoma (OSCC). Carcinogenesis. 25, 269-276, 2004. [JCR]　[WOS]
C. Y. Wang, Y. J. Liang, Y. S. Lin, H. M. Shih, Y. S. Jou and W. C. Yu. YY1AP, a novel co-activator of YY1. J Biol Chem. 279, 17750-17755, 2004. [JCR]　[WOS]
T. S. Huang, C. C. Lee, A. C. Chang, S. Lin, C. C. Chao, Y. S. Jou, Y. W. Chu, C. W. Wu and W. P. Jacqueline. Shortening of microsatellite deoxy(CA) repeats involved in GL331-induced down-regulation of matrix metalloproteinase-9 gene expression. Biochemical and Biophysical Research Communications. 300, 901-907, 2003. [JCR]　[WOS]
S. Y. Wu, C. S. J. Fann, Y. S. Jou, J. W. Chen and W. H. Pan. Association between markers in chromosomal region 17q23 and young onset hypertension: a TDT study. J Med Genet. 39, 42-44, 2002. [JCR]　[WOS]
J. Y. Ko, T. C. Lee, C. F. Hsiao, G. L. Lin, S. H. Yen, K. Y. Chen, C. A. Hsiung, P. J. Chen, M. M. Hsu and Y. S. Jou. Definition of three minimal deleted regions by comprehensive allelotyping and mutational screening of FHIT,p16(INK4A), and p19(ARF) genes in nasopharyngeal carcinoma. Cancer. 94, 1987-1996, 2002. [JCR]　[WOS]
W. L. Ho, J. W. Chang, R. C. Tseng, J. T. Chen, C. Y. Chen, Y. S. Jou and Y. C. Wang. Loss of heterozygosity at loci of candidate tumor suppressor genes in microdissected primary non-small cell lung cancer. Cancer Detect Prev. 26, 343-349, 2002. [JCR]　[WOS]
Y. H. Chen, S. J. Lin, M. W. Lin, H. L. Tsai, S. S. Kuo, J. W. Chen, M. J. Charng, T. C. Wu, L. C. Chen, Y. A. Ding, W. H. Pan, Y. S. Jou and L. Y. Chau. Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients. Hum Genet. 111, 1-8, 2002. [JCR]　[WOS]
Y. T. Tsai, Y. H. Su, S. S. Fang, T. N. Huang, Y. Qiu, Y. S. Jou, H. M. Shih, H. J. Kung and R. H. Chen. Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation. Mol Cell Biol. 20, 2043-2054, 2000. [JCR]　[WOS]
C. Y. Shen, J. C. Yu, Y. L. Lo, C. H. Kuo, C. T. Yue, Y. S. Jou, C. S. Huang, J. C. Lung and C. W. Wu. Genome-wide search for loss of heterozygosity using laser capture microdissected tissue of breast carcinoma: an implication for mutator phenotype and breast cancer pathogenesis. Cancer Res. 60, 3884-3892, 2000. [JCR]　[WOS]
W. H. Pan, J. W. Chen, C. Fann, Y. S. Jou and S. Y. Wu. Linkage analysis with candidate genes: the Taiwan young-onset hypertension genetic study. Hum Genet. 107, 210-215, 2000. [JCR]　[WOS]
S. M. Bell, M. Shaw, Y. S. Jou, R. M. Myers and M. A. Knowles. Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 involved in bladder cancer. Genomics. 44, 163-170, 1997. [JCR]　[WOS]
J. R. Burke, J. J. Enghild, M. E. Martin, Y. S. Jou, R. M. Myers, A. D. Roses, J. M. Vance and W. J. Strittmatter. Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nat Med. 2, 347-350, 1996. [JCR]　[WOS]
Y. S. Jou, R. M. Myers. Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein. Hum Mol Genet. 4, 465-469, 1995. [JCR]　[WOS]
Y. S. Jou, B. Layhe, D. F. Matesic, C. C. Chang, A. W. de Feijter, L. Lockwood, C. W. Welsch, J. E. Klaunig and J. E. Trosko. Inhibition of gap junctional intercellular communication and malignant transformation of rat liver epithelial cells by neu oncogene. Carcinogenesis. 16, 311-317, 1995. [JCR]　[WOS]
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