Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 楊瑞彬 Yang, Ruey-Bing Ray

Journal 89

Lee KH, Lin YC, Tsai MT, Tu CF, Ou SM, Chen HY, Li FA, Tseng WC, Lin YP, Yang RB, Tarng DC. Plasma SCUBE2 as a novel biomarker associates with survival outcomes in patients with sepsis-associated acute kidney injury. Journal of microbiology, immunology, and infection. 57(5), 720-729, 2024.
Lin YC, Chang YJ, Gau SS, Lo CM, Yang RB. SCUBE2 regulates adherens junction dynamics and vascular barrier function during inflammation. Cardiovascular research. 120(13), 1636-1649, 2024.
Lou YC, Tu CF, Chou CC, Yeh HH, Chien CY, Sadotra S, Chen C, Yang RB, Hsu CH. Structural insights into the role of N-terminal integrity in PhoSL for core-fucosylated N-glycan recognition. International journal of biological macromolecules. 255, 128309, 2024.
3.Udesh Dhawan, Wei-Li Wang, Yuh-Charn Lin, Ruey-Bing Yang, Matthew J. Dalby, Manuel Salmeron-Sanchez, Hsiao-Hua Yu. Mechanostimulation-induced integrin αvβ6 and Latency Associated Peptide coupling activates TGF-β and regulates cancer metastasis and stemness. NANO TODAY. 50, 101882, 2023. [JCR]　[WOS]
Yang CW, Hsu HY, Lee YZ, Jan JT, Chang SY, Lin YL, Yang RB, Chao TL, Liang JJ, Lin SJ, Liao CC, Chang CS, Sytwu HK, Hung MS, Chen CT, Lee SJ. Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin. Biochemical pharmacology. 215, 115688, 2023. [JCR]　[WOS]
Tsai MT, Yang RB, Ou SM, Tseng WC, Lee KH, Yang CY, Chang FP, Tarng DC. Plasma Galectin-9 Is a Useful Biomarker for Predicting Renal Function in Patients Undergoing Native Kidney Biopsy. Archives of pathology & laboratory medicine. 147(2), 167-176, 2023.
Sahoo BK, Lin YC, Tu CF, Lin CC, Liao WJ, Li FA, Li LH, Mou KY, Roffler SR, Wang SP, Yeh CT, Yao CY, Hou HA, Chou WC, Tien HF, Yang RB. Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia. Haematologica. 108(5), 1284-1299, 2023.
Lin YC, Sahoo BK, Gau SS, Yang RB. The biology of SCUBE. Journal of biomedical science. 30(1), 33, 2023.
Hu YF, Lee AS, Chang SL, Lin SF, Weng CH, Lo HY, Chou PC, Tsai YN, Sung YL, Chen CC, Yang RB, Lin YC, Kuo TBJ, Wu CH, Liu JD, Chung TW, Chen SA. Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats. Nature biomedical engineering. 6(4), 421-434, 2022. [JCR]　[WOS]
Tamang HK, Yang RB, Song ZH, Hsu SC, Peng CC, Tung YC, Tzeng BH, Chen CC. Ca(v) 3.2 T-type calcium channel regulates mouse platelet activation and arterial thrombosis. Journal of thrombosis and haemostasis : JTH. 20(8), 1887-1899, 2022. [JCR]　[WOS]
Prajnamitra RP, Cheng YY, Beh CY, Lu CY, Lin JH, Ruan SC, Chen SL, Chen HC, Yang RB, Hsieh PC. Depletion of gut microbiota improves the therapeutic efficacy of cancer nanomedicine. Theranostics. 12(17), 7390-7403, 2022. [JCR]　[WOS]
Chou PC, Liu CM, Weng CH, Yang KC, Cheng ML, Lin YC, Yang RB, Shyu BC, Shyue SK, Liu JD, Chen SP, Hsiao M, Hu YF. Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes. Circulation research. 131(1), 6-20, 2022. [JCR]　[WOS]
Liu Y, Guerrero-Juarez CF, Xiao F, Shettigar NU, Ramos R, Kuan CH, Lin YC, de Jesus Martinez Lomeli L, Park JM, Oh JW, Liu R, Lin SJ, Tartaglia M, Yang RB, Yu Z, Nie Q, Li J, Plikus MV. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state. Developmental cell. 57(14), 1758-1775.e7, 2022. [JCR]　[WOS]
Tu CF, Li FA, Li LH, Yang RB. Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness. Breast cancer research : BCR. 24(1), 21, 2022. [JCR]
Lee YZ, Hsu HY, Yang CW, Lin YL, Chang SY, Yang RB, Liang JJ, Chao TL, Liao CC, Kao HC, Chang JY, Sytwu HK, Chen CT, Lee SJ. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b. Pharmaceutics. 14(7), 1511, 2022. [JCR]　[WOS]
Ou SM, Tsai MT, Chen HY, Li FA, Lee KH, Tseng WC, Chang FP, Lin YP, Yang RB, Tarng DC. Urinary Galectin-3 as a Novel Biomarker for the Prediction of Renal Fibrosis and Kidney Disease Progression. Biomedicines. 10(3), 585, 2022. [JCR]　[WOS]
Tsao KC, Lin YC, Chen YT, Lai SL, Yang RB. Zebrafish Scube1 and Scube2 cooperate in promoting Vegfa signalling during embryonic vascularization. Cardiovascular research. 118(4), 1074-1087, 2022. [JCR]　[WOS]
Huang YL, Huang MT, Sung PS, Chou TY, Yang RB, Yang AS, Yu CM, Hsu YW, Chang WC, Hsieh SL. Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection. Communications biology. 4(1), 229, 2021. [JCR]
Kelel M, Yang RB, Tsai TF, Liang PH, Wu FY, Huang YT, Yang MF, Hsiao YP, Wang LF, Tu CF, Liu FT, Lee YL. FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development. The Journal of investigative dermatology. 141(3), 512-522, 2021. [JCR]　[WOS]
Ou SM, Tsai MT, Chen HY, Li FA, Tseng WC, Lee KH, Chang FP, Lin YP, Yang RB, Tarng DC. Identification of Galectin-3 as Potential Biomarkers for Renal Fibrosis by RNA-Sequencing and Clinicopathologic Findings of Kidney Biopsy. Frontiers in medicine. 8, 748225, 2021. [JCR]
Tsai MT, Ou SM, Chen HY, Tseng WC, Lee KH, Yang CY, Yang RB, Tarng DC. Relationship between Circulating Galectin-3, Systemic Inflammation, and Protein-Energy Wasting in Chronic Hemodialysis Patients. Nutrients. 13(8), 2803, 2021. [JCR]
Hsu HY, Yang CW, Lee YZ, Lin YL, Chang SY, Yang RB, Liang JJ, Chao TL, Liao CC, Kao HC, Wu SH, Chang JY, Sytwu HK, Chen CT, Lee SJ. Remdesivir and Cyclosporine Synergistically Inhibit the Human Coronaviruses OC43 and SARS-CoV-2. Frontiers in pharmacology. 12, 706901, 2021. [JCR]
Lin YC, Niceta M, Muto V, Vona B, Pagnamenta AT, Maroofian R, Beetz C, van Duyvenvoorde H, Dentici ML, Lauffer P, Vallian S, Ciolfi A, Pizzi S, Bauer P, Gruning NM, Bellacchio E, Del Fattore A, Petrini S, Shaheen R, Tiosano D, Halloun R, Pode-Shakked B, Albayrak HM, Isik E, Wit JM, Dittrich M, Freire BL, Bertola DR, Jorge AAL, Barel O, Sabir AH, Al Tenaiji AMJ, Taji SM, Al-Sannaa N, Al-Abdulwahed H, Digilio MC, Irving M, Anikster Y, Bhavani GSL, Girisha KM, Haaf T, Taylor JC, Dallapiccola B, Alkuraya FS, Yang RB, Tartaglia M. SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling. American journal of human genetics. 108(1), 115-133, 2021. [JCR]　[WOS]
Su CH, Liao WJ, Ke WC, Yang RB, Tarn WY. The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia. iScience. 24(11), 103368, 2021. [JCR]
Yang Cheng-Wei, Lee Yue-Zhi, Hsu Hsing-Yu, Jan Jia-Tsrong, Lin Yi-Ling, Chang Sui-Yuan, Peng Tzu-Ting, (Yang Ruey-Bing), Liang Jian-Jong, Liao Chun-Che, Chao Tai-Ling, Pang Yu-Hau, Kao Han-Chieh, Huang Wen-Zheng, Lin Jiunn-Horng, Chang Chun-Ping, Niu Guang-Hao, Wu Szu-Huei, Sytwu Huey-Kang, Chen Chiung-Tong, Lee Shiow-Ju. Inhibition of SARS-CoV-2 by Highly Potent Broad-Spectrum Anti-Coronaviral Tylophorine-Based Derivatives. Frontiers in Pharmacology. 11, 606097, 2020-12. [JCR]　[WOS]
Hoti N, Lih TS, Pan J, Zhou Y, Yang G, Deng A, Chen L, Dong M, (Yang RB), Tu CF, Haffner MC, Kay Li Q, Zhang H. A Comprehensive Analysis of FUT8 Overexpressing Prostate Cancer Cells Reveals the Role of EGFR in Castration Resistance. CANCERS. 12(2), 468, 2020-02. [JCR]　[WOS]
Lee YZ, Guo HC, Zhao GH, Yang CW, Chang HY, (Yang RB), Chen L, Lee SJ. Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1alpha. PHARMACOLOGICAL RESEARCH. 152, 104581, 2020-02. [JCR]　[WOS]
Liao WJ, Wu MY, Peng CC, Tung YC, (Yang RB)*. Epidermal growth factor-like repeats of SCUBE1 derived from platelets are critical for thrombus formation. CARDIOVASCULAR RESEARCH. 116(1), 193-201, 2020-01. [JCR]　[WOS]
Liao WJ, Lin H, Cheng CF, Ka SM, Chen A, (Yang RB)*. SCUBE1-enhanced bone morphogenetic protein signaling protects against renal ischemia-reperfusion injury. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 1865(2), 329-338, 2019-02. [JCR]　[WOS]
Lin YC, Liu CY, Kannagi R, (Yang RB)*. Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 38(5), 1202-1215, 2018-05. [JCR]　[WOS]
Yeh HW, Hsu EC, Lee SS, Lang YD, Lin YC, Chang CY, Lee SY, Gu DL, Shih JH, Ho CM, Chen CF, Chen CT, Tu PH, Cheng CF, Chen RH, (Yang RB), Jou YS. PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis. Nature cell biology. 20(4), 479-491, 2018-04. [JCR]　[WOS]
Chao YC, Fleischer J, (Yang RB)*. Guanylyl cyclase-G is an alarm pheromone receptor in mice. The EMBO journal. 37(1), 39-49, 2018. [JCR]　[WOS]
Chen JH, Kuo KT, Bamodu OA, Lin YC, (Yang RB), Yeh CT, Chao TY. Upregulated SCUBE2 expression in breast cancer stem cells enhances triple negative breast cancer aggression through modulation of notch signaling and epithelial-to-mesenchymal transition. EXPERIMENTAL CELL RESEARCH. 370(2), 444-453, 2018. [JCR]　[WOS]
Lin YC, Chao TY, Yeh CT, Roffler SR, Kannagi R, (Yang RB)*. Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 37(1),144-155, 2017-01. [JCR]　[WOS]
Tu CF, Wu MY, Lin YC, Kannagi R, (Yang RB)*. FUT8 promotes breast cancer cell invasiveness by remodeling TGF-beta receptor core fucosylation. Breast cancer research : BCR. 19(1), 111, 2017. [JCR]　[WOS]
Liao WJ, Tsao KC, (Yang RB)*. Electrostatics and N-glycan-mediated membrane tethering of SCUBE1 is critical for promoting bone morphogenetic protein signalling. The Biochemical Journal. 473(5), 661-672, 2016. [JCR]　[WOS]
Lin YC, Roffler SR, Yan YT, (Yang RB)*. Disruption of Scube2 impairs endochondral bone formation. JOURNAL OF BONE AND MINERAL RESEARCH. 30(7), 1255-1267, 2015. [JCR]　[WOS]
Chao YC, Chen CC, Lin YC, Breer H, Fleischer J, (Yang RB)*. Receptor guanylyl cyclase-G is a novel thermosensory protein activated by cool temperatures. EMBO JOURNAL. 34(3), 294-306, 2015. [JCR]　[WOS]
Qiu YQ, Yang CW, Lee YZ, (Yang RB), Lee CH, Hsu HY, Chang CC, Lee SJ. Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget. Oncotarget. 6(4), 2148-2163, 2015. [JCR]　[WOS]
Lin YC, Lee YC, Li LH, Cheng CJ, (Yang RB)*. Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition. JOURNAL OF CELL SCIENCE. 127(1), 85-100, 2014-01. [JCR]　[WOS]
Lin CC, Chang YM, Pan CT, Chen CC, Ling L, Tsao KC, Yang RB, Li WH. Functional Evolution of cardiac microRNAs in heart development and functions. MOLECULAR BIOLOGY AND EVOLUTION. 31(10), 2722-2734, 2014. [JCR]　[WOS]
Lo HC, Yang RB, Lee CH. Guanylyl cyclase-g modulates jejunal apoptosis and inflammation in mice with intestinal ischemia and reperfusion. PLoS One. 9(7), e101314, 2014. [JCR]　[WOS]
Wu MY, Lin YC, Liao WJ, Tu CF, Chen MH, Roffler SR, Yang RB. Inhibition of the plasma SCUBE1, a novel platelet adhesive protein, protects mice against thrombosis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 34(7), 1390-1398, 2014. [JCR]　[WOS]
Tu CF, Tsao KC, Lee SJ, Yang RB. SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development. JOURNAL OF BIOLOGICAL CHEMISTRY. 289(27), 18928-18942, 2014. [JCR]　[WOS]
Hanke W, Mamasuew K, Biel M, Yang RB, Fleischer J. Odorant-evoked electrical responses in Grueneberg ganglion neurons rely on cGMP-associated signaling proteins. NEUROSCIENCE LETTERS. 539, 38-42, 2013-02. [JCR]　[WOS]
Hannema SE, van Duyvenvoorde HA, Premsler T, Yang RB, Mueller TD, Gassner B, Oberwinkler H, Roelfsema F, Santen GW, Prickett T, Kant SG, Verkerk AJ, Uitterlinden AG, Espiner E, Ruivenkamp CA, Oostdijk W, Pereira AM, Losekoot M, Kuhn M, Wit JM. An activating mutation in the kinase homology domain of the natriuretic Peptide receptor-2 causes extremely tall stature without skeletal deformities. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM. 98(12), E1988-E1998, 2013. [JCR]　[WOS]
Tsao KC, Tu CF, Lee SJ, Yang RB. Zebrafish scube1 (Signal Peptide-CUB (Complement Protein C1r/C1s, Uegf, and Bmp1)-EGF (Epidermal Growth Factor) Domain-containing Protein 1) Is Involved in Primitive Hematopoiesis. JOURNAL OF BIOLOGICAL CHEMISTRY. 288(7), 5017-5026, 2013. [JCR]　[WOS]
Chiu TF, Li CH, Chen CC, Chen CH, Cheng CJ, Yan YT, Yang RB. Association of plasma concentration of small heat shock protein B7 with acute coronary syndrome. CIRCULATION JOURNAL. 76(9), 2226-2233, 2012. [JCR]　[WOS]
Fuchs Y, Brunwasser M, Haif S, Haddad J, Shneyer B, Goldshmidt-Tran O, Korsensky L, Abed M, Zisman-Rozen S, Koren L, Carmi Y, Apte R, Yang RB, Orian A, Bejar J, Ron D. Sef is an inhibitor of proinflammatory cytokine signaling, acting by cytoplasmic sequestration of NF-kappaB. DEVELOPMENTAL CELL. 23(3), 611-623, 2012. [JCR]　[WOS]
Klaiber M, Dankworth B, Kruse M, Hartmann M, Nikolaev VO, Yang RB, Volker K, Gassner B, Oberwinkler H, Feil R, Freichel M, Groschner K, Skryabin BV, Frantz S, Birnbaumer L, Pongs O, Kuhn M. A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 108(45), 18500-18505, 2011. [JCR]　[WOS]
Mamasuew K, Hofmann N, Kretzschmann V, Biel M, Yang RB, Breer H, Fleischer J. Chemo- and Thermosensory Responsiveness of Grueneberg Ganglion Neurons Relies on Cyclic Guanosine Monophosphate Signaling Elements. NEUROSIGNALS. 19(4), 198-209, 2011. [JCR]　[WOS]
Lin YC, Chen CC, Cheng CJ, Yang RB. Domain and functional analysis of a novel breast tumor suppressor protein, SCUBE2. JOURNAL OF BIOLOGICAL CHEMISTRY. 286(30), 27039-27047, 2011. [JCR]　[WOS]
Li CH, Yang RB, Pang JH, Chang SS, Lin CC, Chen CH, Chen HY, Chiu TF. Procalcitonin as a biomarker for bacterial infections in patients with liver cirrhosis in the emergency department. ACADEMIC EMERGENCY MEDICINE. 18(2), 121-126, 2011. [JCR]　[WOS]
Wu YY, Peck K, Chang YL, Pan SH, Cheng YF, Lin JC, Yang RB, Hong TM, Yang PC. SCUBE3 is an endogenous TGF-beta receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer. ONCOGENE. 30(34), 3682-3693, 2011. [JCR]　[WOS]
Li HF, Cheng CF, Liao WJ, Lin H, Yang RB. ATF3-Mediated Epigenetic Regulation Protects against Acute Kidney Injury. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 21(6), 1003-1013, 2010-06. [JCR]　[WOS]
Yang RB, Au HK, Tzeng CR, Tsai MT, Wu P, Wu YC, Ling TY, Huang YH. Characterization of a novel cell-surface protein expressed on human sperm. HUMAN REPRODUCTION. 25(1), 42-51, 2010-01. [JCR]　[WOS]
Chao YC, Cheng CJ, Hsieh HT, Lin CC, Chen CC, Yang RB. Guanylate cyclase-G, expressed in the Grueneberg ganglion olfactory subsystem, is activated by bicarbonate. BIOCHEMICAL JOURNAL. 432(2), 267-273, 2010. [JCR]　[WOS]
Zhuang J, Deane JA, Yang RB, Li J, Ricardo SD. SCUBE1, a novel developmental gene involved in renal regeneration and repair. NEPHROLOGY DIALYSIS TRANSPLANTATION. 25(5), 1421-1428, 2010. [JCR]　[WOS]
Chang YC, Kao WC, Wang WY, Wang WY, Yang RB, Peck K. Identification and characterization of oligonucleotides that inhibit Toll-like receptor 2-associated immune responses. FASEB JOURNAL. 23(9), 3078-3088, 2009. [JCR]　[WOS]
Tsai MT, Cheng CJ, Lin YC, Chen CC, Wu AR, Wu MT, Hsu CC, Yang RB. Isolation and characterization of a secreted, cell-surface glycoprotein SCUBE2 from humans. BIOCHEMICAL JOURNAL. 422(1), 119-128, 2009. [JCR]　[WOS]
Chang JC, Yang RB, Adams ME, Lu KH. Receptor guanylyl cyclases in Inka cells targeted by eclosion hormone. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 106(32), 13371-13376, 2009. [JCR]　[WOS]
Cheng CJ, Lin YC, Tsai MT, Chen CS, Hsieh MC, Chen CL, Yang RB. SCUBE2 suppresses breast tumor cell proliferation and confers a favorable prognosis in invasive breast cancer. CANCER RESEARCH. 69(8), 3634-3641, 2009. [JCR]　[WOS]
Lin H, Cheng CF, Hou HH, Lian WS, Chao YC, Ciou YY, Djoko B, Tsai MT, Cheng CJ, Yang RB. Disruption of guanylyl cyclase-G protects against acute renal injury. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 19(2), 339-48, 2008. [JCR]　[WOS]
C. F. Tu, Y. T Yan, S. Y. Wu, B. Djoko, M. T. Tsai, C. J. Cheng and R. B. Yang. Domain and functional analysis of a novel platelet-endothelial cell surface protein, SCUBE1. JOURNAL OF BIOLOGICAL CHEMISTRY. 283(18), 12478-12488, 2008. [JCR]　[WOS]
L. C Milbauer, P. Wei, J. Enenstein, A. Jiang, C. A. Hillery, J. P. Scott, S. C. Nelson, V. Bodempudi, J. N. Topper, R. B. Yang, B. Hirsch, W. Pan and R. Hebbel. Genetic endothelial systems biology of sickle stroke risk. BLOOD. 111(7), 3872-3879, 2008. [JCR]　[WOS]
C. F. Dai, P. Thajeb, C. F. Tu, F. T. Chiang, C. H. Chen. R. B. Yang and J. J. Chen. Plasma concentration of SCUBE1, a novel platelet protein, is elevated in patients with acute coronary syndrome and ischemic stroke. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 51, 2173-2180, 2008. [JCR]　[WOS]
H. Y. Yang, C. F. Cheng, B. Djoko, W. S. Lian, C. F. Tu, M. T. Tsai, Y. H. Chen, C. C. Chen, C. J. Cheng and R. B. Yang. Transgenic overexpression of the secreted, extracellular EGF-CUB domain-containing protein SCUBE3 induces cardiac hypertrophy in mice. CARDIOVASCULAR RESEARCH. 75(1), 139-147, 2007. [JCR]　[WOS]
J. C. Chang, R. B. Yang, Y. H. Chen and K. H. Lu. A novel guanylyl cyclase receptor, BdmGC-1, is highly expressed during the development of the oriental fruit fly Bactrocera dorsalis (Hendel). INSECT MOLECULAR BIOLOGY. 15, 69-77, 2006. [JCR]　[WOS]
C. F. Tu, Y. H. Su, Y. N. Huang, M. T. Tsai, L. T. Li, Y. L. Chen, C. J. Cheng, D. F. Dai and R. B. Yang. Localization and characterization of a novel secreted protein SCUBE1 in human platelets. CARDIOVASCULAR RESEARCH. 71(3), 486-495, 2006. [JCR]　[WOS]
Y. H. Huang, C. C. Wei, Y. H. Su, B. T. Wu, Y. Y. Ciou, C. F. Tu, T. G. Cooper, C. H. Yeung, S. T. Chu, M. T. Tsai and R. B. Yang. Localization and characterization of an orphan receptor, guanylyl cyclase-G, in mouse testis and sperm. ENDOCRINOLOGY. 147(10), 4792-4800, 2006. [JCR]　[WOS]
B. T. Wu, Y. H. Su, M. T. Tsai, S. M. Wasserman, J. N. Topper and R. B. Yang. A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones. JOURNAL OF BIOLOGICAL CHEMISTRY. 279, 37485-37490, 2004. [JCR]　[WOS]
M. Kuhn, C. K. Ng, Y. H. Su, A. Kilic, D. Mitko, N. Bien-Ly, L. G. Komuves and R. B. Yang. Identification of a novel receptor guanylyl cyclase selectively expressed in mouse testis. BIOCHEMICAL JOURNAL. 379, 385-393, 2004. [JCR]　[WOS]
R. B. Yang, C. K. Ng, S. M. Wasserman, L. G. Komuves, M. E. Gerritsen and J. N. Topper. A novel interleukin-17 receptor-like protein identified in human umbilical vein endothelial cells antagonizes basic fibroblast growth factor-induced signaling. JOURNAL OF BIOLOGICAL CHEMISTRY. 278, 33232-33238, 2003. [JCR]　[WOS]
T. K. Nakahashi, K. Hoshina, P. S. Tsao, E. Sho, M. Sho, J. K. Karwowski, C. Yeh, R. B. Yang, J. N. Topper and R. L. Dalman. Flow loading induces macrophage antioxidative gene expression in experimental aneurysms. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 22, 2017-2022, 2002. [JCR]　[WOS]
S. M. Wasserman, F. Mehraban, L. G. Komuves, R. B. Yang, J. E. Tomlinson, Y. Zhang, F. Spriggs and J. N. Topper. Gene expression profile of human endothelial cells exposed to sustained fluid shear stress. PHYSIOLOGICAL GENOMICS. 12, 13-23, 2002. [JCR]　[WOS]
R. B. Yang, C. K. Ng, S. M. Wasserman, S. D. Colman, S. Shenoy, F. Mehraban, L. G. Komuves, J. E. Tomlinson and J. N. Topper. Identification of a novel family of cell-surface proteins expressed in human vascular endothelium. JOURNAL OF BIOLOGICAL CHEMISTRY. 277, 46364-46373, 2002. [JCR]　[WOS]
G. Hollopeter, H. M. Jantzen, D. Vincent, G. Li, L. England, V. Ramakrishnan, R. B. Yang, P. Nurden, A. Nurden, D. Julius and P. B. Conley. Identification of the platelet ADP receptor targeted by antithrombotic drugs. NATURE. 409, 202-207, 2001. [JCR]　[WOS]
A. O. Aliprantis, R. B. Yang, D. S. Weiss, P. Godowski and A. Zychlinsky. The apoptotic signaling pathway activated by Toll-like receptor-2. EMBO JOURNAL. 19, 3325-3336, 2000. [JCR]　[WOS]
A. O. Aliprantis, R. B. Yang, M. R. Mark, S. Suggett, B. Devaux, J. D. Radolf, G. R. Klimpel, P. Godowski and A. Zychlinsky. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. SCIENCE. 285, 736-739, 1999. [JCR]　[WOS]
R. B. Yang, S. W. Robinson, W. H. Xiong, K. W. Yau, D. G. Birch and D. L. Garbers. Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior. JOURNAL OF NEUROSCIENCE. 19, 5889-5897, 1999. [JCR]　[WOS]
H. D. Brightbill, D. H. Libraty, S. R. Krutzik, R. B. Yang, J. T. Belisle, J. R. Bleharski, M. Maitland, M. V. Norgard, S. E. Plevy, S. T. Smale, P. J. Brennan, B. R. Bloom, P. J. Godowski and R. L. Modlin. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. SCIENCE. 285, 732-736, 1999. [JCR]　[WOS]
D. G. Birch, R. B. Yang, S. W. Robinson and D. L. Garbers. Loss of cone and reduction in rod ERG responses in the guanylyl cyclase-E (GC-E) deficient mouse. In: Retinal Degenerative Diseases and Experimental Therapy. 67-80, 1999.
R. B. Yang, M. R. Mark, A. L. Gurney and P. J. Godowski. Signaling events induced by lipopolysaccharide-activated toll-like receptor 2. JOURNAL OF IMMUNOLOGY. 163, 639-643, 1999. [JCR]　[WOS]
R. E. Kelsell, K. Gregory-Evans, A. M. Payne, I. Perrault, J. Kaplan, R. B. Yang, D. L. Garbers, A. C. Bird, A. T. Moore and D. M. Hunt. Mutations in the retinal guanylate cyclase (RETGC-1) gene in dominant cone-rod dystrophy. HUMAN MOLECULAR GENETICS. 7, 1179-1184, 1998. [JCR]　[WOS]
R. B. Yang, M. R. Mark, A. Gray, A. Huang, M. H. Xie, M. Zhang, A. Goddard, W. I. Wood, A. L. Gurney and P. J. Godowski. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. NATURE. 395, 284-288, 1998. [JCR]　[WOS]
Yang RB, Garbers DL. Two eye guanylyl cyclases are expressed in the same photoreceptor cells and form homomers in preference to heteromers. The Journal of Biological Chemistry. 272(21), 13738-13742, 1997. [JCR]　[WOS]
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