Research Findings
Journal 88
- Liang YJ, Teng W, Chen CL, Sun CP, Teng RD, Huang YH, Liang KH, Chen YW, Lin CC, Su CW, Tao MH, Wu JC. Clinical Implications of HBV PreS/S Mutations and the Effects of PreS2 Deletion on Mitochondria, Liver Fibrosis, and Cancer Development. HEPATOLOGY. , 2021. [JCR] [WOS]
- Lien CE, Lin YJ, Chen C, Lian WC, Kuo TY, Campbell JD, Traquina P, Lin MY, Liu LT, Chuang YS, Ko HY, Liao CC, Chen YH, Jan JT, Ma HH, Sun CP, Lin YS, Wu PY, Wang YC, Tao MH*, Lin YL*. CpG-adjuvanted stable prefusion SARS-CoV-2 spike protein protected hamsters from SARS-CoV-2 challenge. Scientific Reports. 11(1), 8761, 2021. [JCR] [WOS]
- Su SH, Yang TJ, Yu PY, Kang-Hao Liang KH, Chen WY, Yang CW, Wang MJ, Lin HT, Lu RM, Tso HC, Chung MJ, Hsieh TY, Chang YL, Lin SC, Fang-Yu Hsu FY, Ke FY, Wu YH, Hwang YC, Liang JJ, Liao CC, Sun CP, Wu PY, Lin YL*, Tao MH*, Liao JC*, Hsu STD*, Wu HC*. Potent neutralizing antibody cocktail for prevention and treatment of COVID-19. PLOS PATHOGENS. , 2021. [JCR]
- Sun CP, Jan JT, Wang IS, Ma HH, Ko HY, Wu PY, Kuo TJ, Liao HN, Lan YH, Sie ZL, Chen YH, Ko YA, Liao CC, Chen LY, Lee IJ, Tsung SI, , Lai YJ, Chiang MT, Liang JJ, Liu WC, Wang JR, Yuan JPY, Lin YS, Tsai YC, Hsieh SL, Li CW, Wu HC, Ko TM, Lin YL*, Tao MH*. Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19. PLOS PATHOGENS. 17(8), e1009758, 2021. [JCR]
- Chung CY, Sun CP, Tao MH, Wu HL, Wang SH, Yeh SH, Zheng QB, Yuan Q, Xia NS, Ogawa K, Nakashima K, Suzuki T, Chen PJ. Major HBV splice variant encoding a novel protein important for infection. Journal of hepatology. S01688278(24), 116, 2024.
- Chou SC, Yen CT, Yang YL, Chen SH, Wang JD, Fan MN, Chen LF, Yu IS, Tsai DY, Lin KI, Tao MH, Wu JC, Lin SW. Recapitulating the immune system of hemophilia A patients with inhibitors using immunodeficient mice. Thrombosis research. 235, 155-163, 2024.
- Lu RM, Liang KH, Chiang HL, Hsu FF, Lin HT, Chen WY, Ke FY, Kumari M, Chou YC, Tao MH, Yi-Ling Lin, Wu HC. Broadly neutralizing antibodies against Omicron variants of SARS-CoV-2 derived from mRNA-lipid nanoparticle-immunized mice. Heliyon. 9(5), e15587, 2023.
- Sun CP, Chiu CW, Wu PY, Tsung SI, Lee IJ, Hu CW, Hsu MF, Kuo TJ, Lan YH, Chen LY, Ng HY, Chung MJ, Liao HN, Tseng SC, Lo CH, Chen YJ, Liao CC, Chang CS, Liang JJ, Draczkowski P, Puri S, Chang YC, Huang JS, Chen CC, Kau JH, Chen YH, Liu WC, Wu HC, Danny Hsu ST, Wang IH, Tao MH. Development of AAV-delivered broadly neutralizing anti-human ACE2 antibodies against SARS-CoV-2 variants. MOLECULAR THERAPY. 31(11), 3322-3336, 2023.
- Kao CY, Pan YC, Hsiao YH, Lim SK, Cheng TW, Huang SW, Wu SM, Sun CP, Tao MH, Mou KY. Improvement of Gene Delivery by Minimal Bacteriophage Particles. ACS nano. 17(15), 14532-14544, 2023.
- Sung PS, Sun CP, Tao MH, Hsieh SL. Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc. EMBO molecular medicine. 15(7), e16351, 2023.
- Huang HC, Wang SH, Fang GC, Chou WC, Liao CC, Sun CP, Jan JT, Ma HH, Ko HY, Ko YA, Chiang MT, Liang JJ, Kuo CT, Lee TA, Morales-Scheihing D, Shen CY, Chen SY, McCullough LD, Cui L, Wernig G, Tao MH, Lin YL, Chang YM, Wang SP, Lai YJ, Li CW. Upregulation of PD-L1 by SARS-CoV-2 promotes immune evasion. JOURNAL OF MEDICAL VIROLOGY. Online ahead of print, Online ahead of print, 2023. [JCR]
- Kumari Monika, Lu Ruei-Min, Li Mu-Chun, Huang Jhih-Liang, Hsu Fu-Fei, Ko Shih-Han, Ke Feng-Yi, Su Shih-Chieh, Liang Kang-Hao, Yuan Joyce Pei-Yi, Chiang Hsiao-Ling, Sun Cheng-Pu, Lee I.-Jung, Li Wen-Shan, Hsieh Hsing-Pang, Tao Mi-Hua, Wu Han-Chung. A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies. Journal of Biomedical Science. 29(1), 68, 2022-9-12. [JCR]
- Lee IJ, Sun CP, Wu PY, Lan YH, Wang IH, Liu WC, Yuan JP, Chang YW, Tseng SC, Tsung SI, Chou YC, Kumari M, Lin YS, Chen HF, Chen TY, Lin CC, Chiu CW, Hsieh CH, Chuang CY, Cheng CM, Lin HT, Chen WY, Hsu FF, Hong MH, Liao CC, Chang CS, Liang JJ, Ma HH, Chiang MT, Liao HN, Ko HY, Chen LY, Ko YA, Yu PY, Yang TJ, Chiang PC, Hsu ST, Lin YL, Lee CC, Wu HC, Tao MH. A booster dose of Delta x Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants. Journal of Biomedical Science. 29(1), 49, 2022. [JCR]
- Jung Lee I, Lan YH, Wu PY, Wu YW, Chen YH, Tseng SC, Kuo TJ, Sun CP, Jan JT, Ma HH, Liao CC, Liang JJ, Ko HY, Chang CS, Liu WC, Ko YA, Chen YH, Sie ZL, Tsung SI, Lin YL, Hsuan Wang I, Tao MH. A receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern. Emerging Microbes & Infections. 1-45, 1-45, 2022. [JCR]
- Hsu FF, Liang KH, Kumari M, Chen WY, Lin HT, Cheng CM, Tao MH, Wu HC. An efficient approach for SARS-CoV-2 monoclonal antibody production via modified mRNA-LNP immunization. International Journal of Pharmaceutics. 627, 122256, 2022. [JCR]
- Sung PS, Yang SP, Peng YC, Sun CP, Tao MH, Hsieh SL. CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation. Journal of Biomedical Science. 29(1), 52, 2022. [JCR]
- Liang Kang-Hao, Chiang Pao-Yin, Ko Shih-Han, Chou Yu-Chi, Lu Ruei-Min, Lin Hsiu-Ting, Chen Wan-Yu, Lin Yi-Ling, Tao Mi-Hua, Jan Jia-Tsrong, Wu Han-Chung. Antibody cocktail effective against variants of SARS-CoV-2. Journal of Biomedical Science. 28(1), 80, 2021-11-23. [JCR]
- Huang HC, Liao CC, Wang SH, Lee IJ, Lee TA, Hsu JM, Kuo CT, Wang J, Hsieh WC, Chang SJ, Chen SY, Tao MH, Lin YL, Lai YJ, Li CW. Hyperglycosylated spike of SARS-CoV-2 gamma variant induces breast cancer metastasis. American Journal of Cancer Research. 11(10), 4994-5005, 2021. [JCR]
- Wu CR, Kim HJ, Sun CP, Chung CY, Lin YY, Tao MH, Kim JH, Chen DS, Chen PJ. Mapping the conformational epitope of a therapeutic monoclonal antibody against HBsAg by in vivo selection of HBV escape variants. Hepatology (Baltimore, Md.). Dec. 27, 00, 2021.
- Huang PH, Tsai HH, Liao BH, Lin YL, Jan JT, Tao MH, Chou YC, Hu CJ, Chen HW. Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain. HUMAN VACCINES & IMMUNOTHERAPEUTICS. 17(3), 654-655, 2021. [JCR] [WOS]
- Tsai TY, Huang MT, Sung PS, Peng CY, Tao MH, Yang HI, Chang WC, Yang AS, Yu CM, Lin YP, Bau CY, Huang CJ, Pan MH, Wu CY, Hsiao CD, Yeh YH, Duan S, Paulson JC, Hsieh SL. SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection. The Journal of Clinical Investigation. 131(11), e141965, 2021. [JCR] [WOS]
- Su SC, Yang TJ, Yu PY, Liang KH, Chen WY, Yang CW, Lin HT, Wang MJ, Lu RM, Tso HC, Chung MJ, Hsieh TY, Chang YL, Lin SC, Hsu FY, Ke FY, Wu YH, Hwang YC, Liu IJ, Liang JJ, Liao CC, Ko HY, Sun CP, Wu PY, Jan JT, Chang YC, Lin YL, Tao MH, Hsu SD, Wu HC. Structure-guided antibody cocktail for prevention and treatment of COVID-19. PLOS Pathogens. 17(10), e1009704, 2021. [JCR]
- Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW. Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro. EBioMedicine. 74, 103712, 2021. [JCR]
- Cheng YW, Chao TL, Li CL, Chiu MF, Kao HC, Wang SH, Pang YH, Lin CH, Tsai YM, Lee WH, Tao MH, Ho TC, Wu PY, Jang LT, Chen PJ, Chang SY, Yeh SH. Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects. CELL REPORTS. 33(2), 108254, 2020-10. [JCR] [WOS]
- Liang YJ, Sun CP, Hsu YC, Chen YW, Wang IA, Su CW, Tao MH, Wu JC. Statin inhibits large hepatitis delta antigen-Smad3 -twist-mediated epithelial-to-mesenchymal transition and hepatitis D virus secretion. JOURNAL OF BIOMEDICAL SCIENCE. 27, 65-81, 2020-05-21. [JCR] [WOS]
- Huang TN, Hsu TT, Lin MH, Chuang HC, Hu HT, Sun CP, Tao MH, Lin JY, Hsueh YP. Interhemispheric Connectivity Potentiates the Basolateral Amygdalae and Regulates Social Interaction and Memory. CELL REPORTS. 29(1), 34-48.e4, 2019-10-01. [JCR] [WOS]
- Lai Ching-Yu, Liu Hsuan, Tin Kai Xuan, Huang Yi, Yeh Kun-Hai, Peng Hubert W., Chen Huan-Da, He Jun-Yu, Chiang Yun-Jung, Liu Chun-Shan, Weng Shih-Yen, Tao Mi-Hua, Yen Jeffrey Jong-Young, Yang-Yen Hsin-Fang. Identification of UAP1L1 as a critical factor for protein O-GlcNAcylation and cell proliferation in human hepatoma cells. Oncogene. 38(3), 317-331, 2019-01. [JCR] [WOS]
- Wu Han-Ming, Tien Yin-Jing, Ho Meng-Ru, Hwu Hai-Gwo, Lin Wen-chang, Tao Mi-Hua, Chen Chun-houh. Covariate-adjusted heatmaps for visualizing biological data via correlation decomposition. Bioinformatics. 34(20), 3529-3538, 2018-10. [JCR] [WOS]
- Tsai Tsung-Yu, Peng Cheng-Yuan, Yang Hwai-I, Huang Ya-Lang, Tao Mi-Hua, Yuan Shin-Sheng, Lai Hsueh-Chou, Hsieh Shie-Liang. The human C-type lectin 18 is a potential biomarker in patients with chronic hepatitis B virus infection. Journal of Biomedical Science. 25(1), 25-59, 2018-07. [JCR] [WOS]
- Wu Chia-Jen, Tsai Yi-Ting, Lee I-Jung, Wu Ping-Yi, Lu Long-Sheng, Tsao Wen-Shan, Huang Yi-Jou, Chang Ching-Cheng, Ka Shuk-Man, Tao Mi-Hua. Combination of radiation and interleukin 12 eradicates large orthotopic hepatocellular carcinoma through immunomodulation of tumor microenvironment. OncoImmunology. 7(9), e1477459, 2018. [JCR] [WOS]
- Li Tian-Neng, Wu Yi-Ju, Tsai Hung-Wen, Sun Cheng-Pu, Wu Yi-Hsuan, Wu Hui-Lin, Pei Yi-Ning, Lu Kuan-Ying, Yen Tim Ting-Chung, Chang Chien-Wen, Chan Hong-Lin, Tao Mi-Hua, Liou Jun-Yang, Chang Margaret Dah-Tsyr, Su Ih-Jen, Wang Lily Hui-Ching. Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis. The Journal of Pathology. 245(4), 502-513, 2018. [JCR] [WOS]
- Tsai WL, Yeh PH, Tsai CY, Ting CT, Chiu YH, Tao MH, Li WC, Hung SC. Efficient Programming of Human Mesenchymal Stem Cell Derived Hepatocytes by Epigenetic Regulations. Journal of Gastroenterology and Hepatology. 32(1), 261-269, 2017-01. [JCR] [WOS]
- Chan CC, Lai CW, Wu CJ, Chen LC, Tao MH, Kuo ML. Liver-Specific Allergen Gene Transfer by Adeno-Associated Virus Suppresses Allergic Airway Inflammation in Mice. Human Gene Therapy. 27(8), 631-642, 2016. [JCR] [WOS]
- Zhang TY, Yuan Q, Zhao JH, Zhang YL, Yuan LZ, Lan Y, Lo YC, Sun CP, Wu CR, Zhang JF, Zhang Y, Cao JL, Guo XR, Liu X, Mo XB, Luo WX, Cheng T, Chen YX, Tao MH, Shih JW, Zhao QJ, Zhang J, Chen PJ, Yuan YA, Xia NS. Prolonged suppression of HBV in mice by a novel antibody that targets a unique epitope on hepatitis B surface antigen. Gut. 65(4), 658-671, 2016. [JCR] [WOS]
- Shih YM, Sun CP, Chou HH, Wu TH, Chen CC, Wu PY, Enya Chen YC, Bissig KD, Tao MH. Combinatorial RNA Interference Therapy Prevents Selection of Pre-existing HBV Variants in Human Liver Chimeric Mice. Scientific reports. 5, 15259, 2015. [JCR] [WOS]
- Shu SA, Wang J, Tao MH, Leung PS. Gene Therapy for Autoimmune Disease. Clinical reviews in allergy & immunology. 49(2), 163-176, 2015. [JCR] [WOS]
- Hsieh YT, Chen KC, Cheng CM, Cheng TL, Tao MH, Roffler SR. Impediments to enhancement of CPT-11 anticancer activity by E. coli directed beta-glucuronidase therapy. PloS one. 10(2), e0118028, 2015. [JCR] [WOS]
- Huang JY, Chou SF, Lee JW, Chen HL, Chen CM, Tao MH, Shih C. MicroRNA-130a can inhibit hepatitis B virus replication via targeting PGC1alpha and PPARgamma. RNA. 21(3), 385-400, 2015. [JCR] [WOS]
- Huang HC, Tao MH, Hung TM, Chen JC, Lin ZJ, Huang C. (-)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes. Antiviral research. 111, 100-111, 2014. [JCR] [WOS]
- Chen HW, Huang HW, Hu HM, Chung HH, Wu SH, Chong P, Tao MH, Pan CH. A poorly neutralizing IgG2a/c response elicited by a DNA vaccine protects mice against Japanese encephalitis virus. The Journal of general virology. 95(Pt 9), 1983-1990, 2014. [JCR] [WOS]
- Hsiao HB, Chou AH, Lin SI, Lien SP, Liu CC, Chong P, Chen CY, Tao MH, Liu SJ. Delivery of human EV71 receptors by adeno-associated virus increases EV71 infection-induced local inflammation in adult mice. Biomed research international. 2014, 878139, 2014. [JCR] [WOS]
- Lin JC, Lin SC, Chen WY, Yen YT, Lai CW, Tao MH, Lin YL, Miaw SC, Wu-Hsieh BA. Dengue viral protease interaction with NF-kappaB inhibitor alpha/beta results in endothelial cell apoptosis and hemorrhage development. Journal of immunology. 193(3), 1258-1267, 2014. [JCR] [WOS]
- Chang CH, Chen YC, Yu YH, Tao MH, Leung PS, Ansari AA, Gershwin ME, Chuang YH. Innate immunity drives xenobiotic-induced murine autoimmune cholangitis. Clinical and experimental immunology. 177(2), 373-380, 2014. [JCR] [WOS]
- Chen, R. C., P. Naiyanetr, S. A. Shu, J. Wang, G. X. Yang, T. P. Kenny, K. C. Guggenheim, J. D. Butler, C. Bowlus, M. H. Tao, M. J. Kurth, A. A. Ansari, M. Kaplan, R. L. Coppel, A. Lleo, M. E. Gershwin & P. S. Leung. Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis. HEPATOLOGY. 57(4), 1498-1508, 2013. [JCR] [WOS]
- Lin, J. T., W. C. Chang, H. M. Chen, H. L. Lai, C. Y. Chen, M. T. Tao & Y. Chern. Feedback regulation between protein kinase A and the proteasome system worsens Huntington's disease. MOLECULAR AND CELLULAR BIOLOGY. 33(5), 1073-1084, 2013. [JCR] [WOS]
- Kao, C. Y., S. J. Yang, M. H. Tao, Y. M. Jeng, I. S. Yu & S. W. Lin. Incorporation of the factor IX Padua mutation into FIX-Triple improves clotting activity in vitro and in vivo. THROMBOSIS AND HAEMOSTASIS. 110(2), 244-256, 2013. [JCR] [WOS]
- Sun, C. P., T. H. Wu, C. C. Chen, P. Y. Wu, Y. M. Shih, K. Tsuneyama & M. H. Tao*. Studies of Efficacy and Liver Toxicity Associated With AAV-mediated RNA Interference. HUMAN GENE THERAPY. 24(8), 739-750, 2013. [JCR] [WOS]
- Pan, W. Y., C. H. Lo, C. C. Chen, P. Y. Wu, S. R. Roffler, S. K. Shyue, & M. H. Tao*. Cancer immunotherapy using a membrane-bound interleukin 12 with B7-1 transmembrane and cytoplasmic domains. MOLECULAR THERAPY. 20(5), 927-937, 2012. [JCR] [WOS]
- Huang, H. C., C. C. Chen, W.C. Chang, M. H. Tao & C. Huang. Entry of hepatitis B virus into immortalized human primary hepatocytes by clathrin-dependent endocytosis. JOURNAL OF VIROLOGY. 86(17), 9443-9453, 2012. [JCR] [WOS]
- Hsu, Y. C., H. P. Huang, I. S. Yu, K. Y. Su, S. R. Lin, W. C. Lin, H. L. Wu, G. Y. Shi, M. H. Tao, C. H. Kao, Y. M. Wu, P. E. Martin, S. Y. Lin, P. C. Yang, & S. W. Lin. Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells via hepatocyte growth factor signaling. HEPATOLOGY. 56(5), 1913-1923, 2012. [JCR] [WOS]
- Chen, C. C., C. M. Chang, C. P. Sun, C. P. Yu, P. Y. Wu, K. S. Jeng, C. P. Hu, P. J. Chen, J. C. Wu, C. Shih, M. E. Gershwin, & M. H. Tao*. Use of RNA Interference to Modulate Liver Adenoma Development in A Murine Model Transgenic for Hepatitis B Virus. GENE THERAPY. 19(1), 25-33, 2012. [JCR] [WOS]
- Huang, Y. H., C. C. Fang, K. Tsuneyama, H. Y. Chou, W. Y. Pan, Y. M. Shih, P. Y. Wu, Y. Chen, P. S. Leung, M. E. Gershwin & M. H. Tao*. A murine model of hepatitis B-associated hepatocellular carcinoma generated by adeno-associated virus-mediated gene delivery. INTERNATIONAL JOURNAL OF ONCOLOGY. 39(6), 1511-1519, 2011. [JCR] [WOS]
- Ju, T.C., H. M. Chen, J. T. Lin, C. P. Chang, W. C. Chang, J. J. Kang, C. P. Sun, M. H. Tao, P. H. Tu, C. Chang, D. W. Dickson, & Y. Chern. Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease. JOURNAL OF CELL BIOLOGY. 194(2), 209-227, 2011. [JCR] [WOS]
- Song, Y. C., A. H. Chou, A. Homhuan, M. H. Huang, S. K. Chiang, K. Y. Shen, P. W. Chuang, C. H. Leng, M. H. Tao, P. Chong & S. Liu. Presentation of lipopeptide by dendritic cells induces anti-tumor responses via an endocytosis-independent pathway in vivo. JOURNAL OF LEUKOCYTE BIOLOGY. 90(2), 323-332, 2011. [JCR] [WOS]
- Leung P. S., A. Dhirapong, P. Y. Wu, & M. H. Tao. Gene therapy in autoimmune diseases: Challenges and opportunities. AUTOIMMUNITY REVIEWS. 9(3), 170-174, 2010. [JCR] [WOS]
- Li, Y. C., B. M. Chen, P. C. Wu, T. L. Cheng, L. S. Kao, M. H. Tao, A. Lieber, S. R. Roffler. Cutting Edge: Mechanical Forces Acting on T Cells Immobilized via the TCR Complex Can Trigger TCR Signaling. JOURNAL OF IMMUNOLOGY. 184(11), 5959-5963, 2010. [JCR] [WOS]
- Leung P. S., S. A. Shu, T. P. Kenny, P. Y. Wu, & M. H. Tao. Development and validation of gene therapies in autoimmune diseases: Epidemiology to animal models. AUTOIMMUNITY REVIEWS. 9(5), A400-A405, 2010. [JCR] [WOS]
- Lo, C. H., C. M. Chang, S. W. Tang, W. Y. Pan, C. C. Fang, Y. Chen, P. Y. Wu, K. Y. Chen, H. I. Ma, X. Xiao, & M. H. Tao. Differential antitumor effect of interleukin 12 family cytokines on orthotopic hepatocellular carcinoma. JOURNAL OF GENE MEDICINE. 12(5), 423-434, 2010. [JCR] [WOS]
- Kao, C. Y., C. N. Lin, I. S. Yu, M. H. Tao, H. L. Wu, G. Y. Shi, Y. L. Yang, J. T. Kao & S. W. Lin. FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis. THROMBOSIS AND HAEMOSTASIS. 104(2), 355-365, 2010. [JCR] [WOS]
- Chou, H. Y., X. Z. Lin, W. Y. Pan, P. Y. Wu, C. M. Chang, T. Y. Lin, H. H. Shen & M. H. Tao. Hydrogel-Delivered GM-CSF Overcomes Nonresponsiveness to Hepatitis B Vaccine through the Recruitment and Activation of Dendritic Cells. JOURNAL OF IMMUNOLOGY. 185(9), 5468-5475, 2010. [JCR] [WOS]
- Chang, C. M., C. H. Lo, Y. M. Shih, Y. Chen, P. Y. Wu, K. Tsuneyama, S. R. Roffler, & M. H. Tao. Treatment of hepatocellular carcinoma with adeno-associated virus encoding interleukin-15 superagonist. HUMAN GENE THERAPY. 21(5), 611-621, 2010. [JCR] [WOS]
- Chen, C. C., C. P. Sun, H. I. Ma, C. C. Fang, P. Y. Wu, X. Xiao, & M. T. Tao. Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9. MOLECULAR THERAPY. 17, 352-359, 2009. [JCR] [WOS]
- Chuang, T. F., S. C. Lee, K. W. Liao, Y. W. Hsiao, C. H. Lo, B. L. Chiang, X. Z. Lin, M. H. Tao*, & R. M. Chu. Electroporation-mediated IL-12 gene therapy in a canine cancer model. INTERNATIONAL JOURNAL OF CANCER. 125(3), 698-707, 2009. [JCR] [WOS]
- Ho, M. Y., S. J. Leu, G. G. Sun, M. H. Tao, S. J. Tang & K. H. Sun. IL-27 directly restrains lung tumorigenicity by suppressing cyclooxygenase-2-mediated activities. JOURNAL OF IMMUNOLOGY. 183(10), 6217-6226, 2009. [JCR] [WOS]
- W. Liou, Y. J. Sung, M. H. Tao and S. J. Lo. Morphogenesis of the hepatitis B virion and subviral particles in the liver of transgenic mice. J Biomed Sci. 15(3), 311-316, 2008. [JCR] [WOS]
- C. C. Chen, T. M. Ko, H. I. Ma, H. L. Wu, X. Xiao, J. Li, C. M. Chang, P. Y. Wu, C. H. Chen, J. M. Han, C. P. Yu, K. S. Jeng, C. P. Hu and M. H. Tao. Long-term inhibition of hepatitis B virus in transgenic mice by double-stranded adeno-associated virus 8-delivered short hairpin RNA. Gene Ther. 14(1), 11-19, 2007. [JCR] [WOS]
- Y. T. Shiau, Y. H. Huang, J. C. Wu, M. H. Tao, W. J. Syu, F. Y. Chang and S. D. Lee. Analysis of humoral immunity of hepatitis D virus DNA vaccine generated in mice ny using different dosage, gene gun immunization, and in vivo electroporation. J Chin Med Assoc. 69(1), 7-13, 2006. [JCR]
- C. H. Chen, K. Y. Su, M. H. Tao, S. W. Lin, Y. H. Su, Y. C. Tsai, K. C. Cheng, Y. M. Jeng and J. C. Sheu. Decreased expressions of hepsin in human hepatocellular carcinomas. Liver Int. 26(7), 774-780, 2006. [JCR] [WOS]
- C. J. Wu, T. L. Li, H. W. Huang, M. H. Tao and Y. L. Chan. Development of an effective Japanese encephalitis virus-specific DNA vaccine. Microbes Infect. 8(11), 2578-2586, 2006. [JCR] [WOS]
- S. A. Kim, C. M. Liang, I. C. Cheng, Y. C. Cheng, M. T. Chiao, C. J. Tseng, F. Lee, M. H. Jong, M. H. Tao, N. S. Yang and S. M. Liang. DNA vaccination against foot-and-mouth disease via electroporation: study of molecular approaches for enhancing VP1 antigenicity. J Gene Med. 8(9), 1182-1191, 2006. [JCR] [WOS]
- Z. Nie, Y. K. Tzeng, H. C. CHang, C. C. Chiu, C. Y. Chang, C. M. Chang and M. H. Tao. Microscopy-based mass measurement of a single whole virus in a cylindrical on trap. Angew Chem Int Edit. 45(48), 8131-8134, 2006. [JCR] [WOS]
- Y. H. Huang, M. H. Tao, C. P. Hu, W. J. Shu and J. C. Wu. Identification of novel HLA-A*0201-restricted CD8+ T-cell epitopes on hepatitis delta virus. J Gen Virol. 85, 3089-3098, 2005. [JCR] [WOS]
- H. I. Huang, P. Y. Wu, C. Y. Teo, M. N. Chen, Y. C. Chen, D. Silin and M. H. Tao. Improved immunogenicity of a self tumor antigen by covalent linkage to CD40 ligand. Int J Cancer. 108, 696-703, 2004. [JCR] [WOS]
- C. J. Wu, S. C. Lee, H. W. Huang and M. H. Tao. In vivo electroporation of skeletal muscles increases the efficacy of Japanese encephalitis virus DNA vaccine. Vaccine. 22, 1457-1464, 2004. [JCR] [WOS]
- C. H. Lo, S. C. Lee, P. Y. Wu, W. Y. Pan, J. Su, C. W. Cheng, S. R. Roffler, B. L. Chiang, C. N. Lee, C. W. Wu and M. H. Tao. Antitumor and antimetastatic activity of IL-23. J Immunol. 171, 600-607, 2003. [JCR] [WOS]
- C. J. Wu, H. W. Huang and M. H. Tao. Induction of cross-protection against two wild-type Taiwanese isolates of Japanese encephalitis virus using Beijing-1 strain DNA vaccine. Vaccine. 21, 3938-3945, 2003. [JCR] [WOS]
- H. W. Chen, H. I. Huang, Y. P. Lee, L. L. Chen, H. K. Liu, M. L. Cheng, J. P. Tsai, M. H. Tao and C. C. Ting. Linkage of CD40L to a self-tumor antigen enhances the antitumor immune responses of dendritic cell-based treatment. Cancer Immunol Immunother. 51, 341-348, 2002. [JCR] [WOS]
- C. H. Pan, H. W. Chen, H. W. Huang and M. H. Tao. Protective mechanisms induced by a Japanese encephalitis virus DNA vaccine: requirement for antibody but not CD8(+) cytotoxic T-cell responses. J Virol. 75, 11457-11463, 2001. [JCR] [WOS]
- H. W. Chen, C. H. Pan, H. W. Huan, M. Y. Liau, J. R. Chiang and M. H. Tao. Suppression of immune response and protective immunity to a Japanese encephalitis virus DNA vaccine by coadministration of an IL-12-expressing plasmid. J Immunol. 166, 7419-7426, 2001. [JCR] [WOS]
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