Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 李福安 Li, Fu-An

Journal 44

Yi-Cheng Chang, Meng-Lun Hsieh, Hsiao-lin Lee, Siow-Wey Hee, Chi-Fon Chang, Hsin-Yung Yen, Yi-An Chen, Yet-Ran Chen, Ya-Wen Chou, (Fu-An Li), Yi-Yu Ke, Shih-Yi Chen, Ming-Shiu Hung, Alfur Fu-Hsin Hung, Jing-Yong Huang, Chu-Hsuan Chiu, Shih-Yao Lin, Sheue-Fang Shih, Chih-Neng Hsu, Juey-Jen Hwang, Teng-Kuang Yeh, Ting-Jen Rachel Cheng, Karen Chia-Wen Liao, Daniel Laio, Chun-Mei Hu, Shu-Wha Lin, Tzu-Yu Chen, Ulla Vogel, Daniel Saar, Birthe Kragelund, Lun Kelvin Tsou*, Yu-Hua Tseng*, Lee-Ming Chuang*. Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity. EMBO MOLECULAR MEDICINE. , 2025-03. [JCR]　[WOS]
Chi-Long Lin, Zih-Syun Fang, Chung-Yao Hsu, Yu-Han Liu, Jung-Chen Lin, Bing-Yu Yao, (Fu-An Li), Shin-Chwen Bruce Yen, Yuan-Chih Chang and Che-Ming J. Hu*. Rapid plasma membrane isolation via intracellular polymerization-mediated biomolecular confinement. ACTA BIOMATERIALIA. , 2023-11. [JCR]　[WOS]
Yi-Cheng Chang, Hsiao-Lin Lee, Wenjin Yang, Meng-Lun Hsieh, Cai-Cin Liu, Tung-Yuan Lee, Jing-Yong Huang, Jiun-Yi Nong, (Fu-An Li), Hsiao-Li Chuang, Zhi-Zhong Ding, Wei-Lun Su, Li-Yun Chueh, Yi-Ting Tsai, Che-Hong Chen, Daria Mochly-Rosen,* and Lee-Ming Chuang*. A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators. NATURE COMMUNICATIONS. 14, 5971, 2023-09. [JCR]　[WOS]
Kai-Hsuan Wang, Jing-Yang Chang, (Fu-An Li), Kuan-Yi Wu, Shu-Hao Hsu, Yen-Ju Chen, Tse-Ling Chu, Jessica Lin, and Hong-Ming Hsu*. An atypical F-actin capping protein modulates cytoskeleton behaviors crucial to Trichomonas vaginalis colonization. MICROBIOLOGY SPECTRUM. , 2023-06. [JCR]　[WOS]
Yung-Hui Kuan, (Fu-An Li), Sin-Jhong Cheng, Wei-Peng Chang, Bai-Chuang Shyu*. Modulation of thalamocingulate nociceptive transmission and glutamate secretion by targeting P2X7 receptor. The Journal of Pain. , 2023-06. [JCR]　[WOS]
Ruey-Bing Yang, Cheng-Fen Tu, Yan- Ting Chen, The Huong Chau, Shu-Wha Lin, Cheng-Da Tsai, (Fu-An Li), Morten Andersen, and Yuh-Charn Lin*. FUT8-dependent core fucosylation: essential for platelet function and a target in thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. , .
Chen Ping‐Chen, Liu Chen‐Kai, Tsai Ching‐Chung, Sulistyowati Erna, (Li Fu‐An), Liu Chung‐Jung, Wu Deng‐Chyang, Chou Shih‐Hsuan, Kuo Fu‐Chen, Huang Bin. Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells. The Kaohsiung Journal of Medical Sciences. issue e70232, 1-12, 2026-05. [JCR]
Wen-Rui Hao, Chun-Chao Chen, (Fu-An Li), Huan-Yuan Chen, Ju-Chi Liu, Tzu-Hurng Cheng*, and Jin-Jer Chen. Therapeutic Impact of Vericiguat on Ventricular Remodeling in a Pressure-Overload Heart Failure Model. Life. 15(11), 1763, 2025-11-18. [JCR]　[WOS]
Kuo-Hua Lee, Yuh-Charn Lin, Ming-Tsun Tsai, Cheng-Fen Tu, Shuo-Ming Ou, Huan-Yuan Chen, (Fu-An Li), Wei-Cheng Tseng, Yao-Ping Lin, Ruey-Bing Yang*, Der-Cherng Tarng*. Plasma SCUBE2 as a novel biomarker associates with survival outcomes in patients with sepsis-associated acute kidney injury. Journal of Microbiology, Immunology and Infection. 57(5), 720-729, 2024-10. [JCR]　[WOS]
Siow-Wey Hee, Yi-Cheng Chang, Lynn Su, Ing-Jung Chen, Yung-Ming Jeng, Meng-Lun Hsieh, Yu-Chia Chang, (Fu-An Li), Daniel Liao, Shiau-Mei Chen, and Lee-Ming Chuang*. 15-keto-PGE2 alleviates nonalcoholic steatohepatitis through its covalent modification of NF-kB factors. iScience. 26, 107997, 2023-09. [JCR]　[WOS]
Binay K Sahoo, Yuh-Charn Lin, Cheng-Fen Tu, Chien-Chin Lin, Wei-Ju Liao, (Fu-An Li), Ling-Hui Li, Kurt Yun Mou, Steve R Roffler, Shu-Ping Wang, Chi-Tai Yeh, Chi-Yuan Yao, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Ruey-Bing Yang*. Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia. HAEMATOLOGICA. 108(5), 1284-1299, 2023-05. [JCR]　[WOS]
Hui-Ju Yang*, Haruhiko Asakawa, (Fu-An Li), Tokuko Haraguchi, Hsiu-Ming Shih, Yasushi Hiraoka*. A nuclear pore complex-associated regulation of SUMOylation in meiosis. GENES TO CELLS. 28(3), 188-201, 2023-03. [JCR]　[WOS]
Yu-Jih Su, (Fu-An Li), Jim Jinn-Chyuan Sheu, Sung-Chou Li, Shao-Wen Weng, Feng-Chih Shen, Yen-Hsiang Chang, Huan-Yuan Chen, Chia-Wei Liou, Tsu-Kung Lin, Jiin-Haur Chuang, Pei-Wen Wang*. A Study on MDA5 Signaling in Splenic B Cells from an Imiquimod-Induced Lupus Mouse Model with Proteomics. CELLS. 11(21), 3350, 2022-10. [JCR]　[WOS]
Shih-Han Wang, Wen-Cheng Chou, Hsiang-Chi Huang, Te-An Lee, Tzu-Chun Hsiao, Ling-Hui Wang, Ke-Bin Huang, Chun-Tse Kuo, Chi-Hong Chao, Shing-Jyh Chang, Jung-Mao Hsu, Jialei Weng, Ning Ren, (Fu-An Li), Yun-Ju Lai, Chenhao Zhou, Mien-Chie Hung, Chia-Wei Li*. Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis. AMERICAN JOURNAL OF CANCER RESEARCH. 12(10), 4721-4736, 2022-10. [JCR]　[WOS]
Cheng‑Fen Tu, (Fu‑An Li), Ling‑Hui Li and Ruey‑Bing Yang*. Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness. Breast Cancer Research. 24:21, 0, 2022-03. [JCR]　[WOS]
Shuo-Ming Ou, Ming-Tsun Tsai, Huan-Yuan Chen, (Fu-An Li), Kuo-Hua Lee, Wei-Cheng Tseng, Fu-Pang Chang, Yao-Ping Lin, Ruey-Bing Yang* and Der-Cherng Tarng*. Urinary Galectin-3 as a Novel Biomarker for the Prediction of Renal Fibrosis and Kidney Disease Progression. Biomedicines. 10(3), 585, 1-13, 2022-03. [JCR]　[WOS]
Shuo-Ming Ou, Ming-Tsun Tsai, Huan-Yuan Chen, (Fu-An Li), Wei-Cheng Tseng, Kuo-Hua Lee, Fu-Pang Chang, Yao-Ping Lin, Ruey-Bing Yang* and Der-Cherng Tarng*. Identification of Galectin-3 as Potential Biomarkers for Renal Fibrosis by RNA-Sequencing and Clinicopathologic Findings of Kidney Biopsy. Frontiers in medicine. 8:748225, 0, 2021-11. [JCR]　[WOS]
Hsiang-Chi Huang, Yun-Ju Lai, Chun-Che Liao, Wang-Feng Yang, Ke-Bin Huang, I-Jung Lee, Wen-Cheng Chou, Shih-Han Wang, Ling-Hui Wang, Jung-Mao Hsu, Cheng-Pu Sun, Chun-Tse Kuo, Jyun Wang, Tzu-Chun Hsiao, Po-Jiun Yang, Te-An Lee, Wilson Huang, (Fu-An Li), Chen-Yang Shen, Yi-Ling Lin, Mi-Hua Tao, Chia-Wei Li*. Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro. eBioMedicine. 74, 103712, 2021-11. [JCR]　[WOS]
Ya-Lin Lin, Mei-Yi Lu, Chi-Fen Chuang, Yali Kuo, Hong-En Lin, (Fu-An Li), Jen-Ren Wang, Yi-Ping Hsueh, Fang Liao*. TLR7 is critical for anti-viral humoral immunity to EV71 infection in the spinal cord. Frontiers in Immunology. 11, 614743, 2021-02. [JCR]　[WOS]
Yaw-Wen Hsu, Fu-Fei Hsu, Ming-Tsai Chiang, Dong-Lin Tsai, (Fu-An Li), Takashi Angata, Paul R Crocker, Lee-Young Chau*. Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation. Journal of Biomedical Science. 28(1), 5, 2021-01. [JCR]　[WOS]
Hung Chih-Chang, (Li Fu-An), Liang Shih-Shin, Wang Ling-Feng, Lin I-Ling, Chiu Chien-Chih, Lee Chiu-Hsien, Chen Jeff Yi-Fu*. Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells. Molecules. 25(17),3815, 2020-09. [JCR]　[WOS]
Meng-Sen Huang, Jen-Hsuan Chang, Wen-Ching Lin, Yu-Hsiang Cheng, (Fu-An Li), Ching-Shu Suen, Ming-Jing Hwang, Chung-Ke Chang*, Kurt Yun Mou*. SLC38A2 Overexpression Induces a Cancer-like Metabolic Profile and Cooperates with SLC1A5 in Pan-cancer Prognosis. Chemistry – An Asian Journal. 15(22), 3861-3872, 2020-09. [JCR]　[WOS]
Sudhakar Janaki N., Lu Hsueh-Han, Chiang Hung-Yu, Suen Ching-Shu, Hwang Ming-Jing, Wu Sung-Yu, Shen Chia-Ning, Chang Yao-Ming, (Li Fu-An), Liu Fu-Tong, Shui Jr-Wen*. Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas. Nature Communications. 11(1), 2020-08. [JCR]　[WOS]
Cheng-Hao Liu, Ming-Jou Chien, You-Chiun Chang, Yu-Hsiang Cheng, (Fu-An Li), and Kurt Yun Mou*. Combining Proximity Labeling and Cross-Linking Mass Spectrometry for Proteomic Dissection of Nuclear Envelope Interactome. Journal of Proteome Research. 2020, 19, 3, 1109-1118, 2020-03. [JCR]　[WOS]
Wun-Rong Lin, Chung-Jung Liu, Yaw-Syan Fu, (Fu-An Li), and Bin Huang*. Comparison of the protein acetylome of endothelial cells upon shear flow and resveratrol treatment. Cardiology Journal. DOI: 10.5603/CJ.a2020.0029, 2020-02. [JCR]
Jing-You Guo, Chu-Hsuan Chiu, Mei-Jung Wang, (Fu-An Li), and Jeou-Yuan Chen*. Proteoglycan serglycin promotes non-small cell lung cancer cell migration through the interaction of its glycosaminoglycans with CD44. Journal of Biomedical Science. 27(1), 2020-01. [JCR]　[WOS]
Fu-Fei Hsu, Yi-Tai Chou, Ming-Tsai Chiang, (Fu-An Li), Chi-Tai Yeh, Wei-Hwa Lee, and Lee-Young Chau*. Signal peptide peptidase promotes tumor progression via facilitating FKBP8 degradation. Oncogene. 38(10),1688–1701, 2019-03. [JCR]　[WOS]
Chao‐Wen Cheng, Che‐Chang Chang, Yudha Nur Patria, Ruei‐Ting Chang, Yun‐Ru Liu, (Fu‐An Li), Hsiu‐Ming Shih*, and Ching‐Yu Lin*. Sex hormone-binding globulin (SHBG) is a potential early diagnostic biomarker for gastric cancer. Cancer Medicine. 7(1), 64-74, 2018-01. [JCR]　[WOS]
Hsu F-F, Chiang M-T, (Li F-A), Yeh C-T, Lee W-H, and Chau L-Y*. Acetylation is essential for nuclear heme oxygenase-1-enhanced tumor growth and invasiveness. Oncogene. 36(49), 6805-6814, 2017-12. [JCR]　[WOS]
Lin MC, Hsing CH, (Li FA), Wu CH, Fu YS, Cheng JK, Huang B. Rosuvastatin Modulates the Post-Translational Acetylome in Endothelial Cells. Acta Cardiologica Sinica. 30(1), 67-73, 2014. [JCR]　[WOS]
Hsu F-F, Yeh C-T, Sun Y-J, Chiang M-T, Lan W-M, (Li F-A), Lee W-H, Chau L-Y. Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity. Oncogene. 34(18), 2360-2370, 2014. [JCR]　[WOS]
Shieh YH, Chen CC, (Li FA), Cheng JK, Lin MC, Huang B. The Translational Proteome Modulated by 20(S)-Protopanaxadiol in Endothelial Cells. Acta Cardiologica Sinica. 30(5), 466-73, 2014. [JCR]　[WOS]
Huang Bin, Wu Chien-Hsing, (Li Fu-An), Liang Shih-Shin, Shieh Ying-Hua, Wang Ling Danny. Rosuvastatin-regulated post-translational phosphoproteome in human umbilical vein endothelial cells. The Kaohsiung Journal of Medical Sciences. 29(7), 347-352, 2013. [JCR]　[WOS]
Chen Chun-Hau, Chang Che-Chang, Lee Tae Ho, Luo ManLi, Huang Pengyu, Liao Pei-Hsin, Wei Shuo, (Li Fu-An), Chen Ruey-Hwa, Zhou Xiao Zhen, Shih Hsiu-Ming, Lu Kun Ping. SENP1 deSUMOylates and Regulates Pin1 Protein Activity and Cellular Function. Cancer Research. 73(13), 3951-3962, 2013. [JCR]　[WOS]
Bin Huang, (Fu An Li), Chien Hsing Wu and Danny Ling Wang*. The role of nitric oxide on rosuvastatin-mediated S-nitrosylation and translational proteomes in human umbilical vein endothelial cells. Proteome Science. 10(1), 43, 2012. [JCR]　[WOS]
Huang Ju-Li, (Li Fu-An), Her Guor-Rong*. A comparative study of interfaces for microchip micellar electrokinetic chromatography-electrospray ionization mass spectrometry using the surfactant ammonium dodecyl sulfate. ELECTROPHORESIS. 32(23), 3385-3391, 2011. [JCR]　[WOS]
Liu Yi-Lin, Wang Nan-Hsuan, (Li Fu-An), Her Guor-Rong*. A liquid-junction/low-flow interface for sensitivity improvement in micelle electrokinetic chromatography–electrospray ionization-mass spectrometry. Journal of Chromatography A. 1216(49), 8671-8675, 2009. [JCR]　[WOS]
(Li Fu-An), Huang Ju-Li, Her Guor-Rong*. Chip-CE/MS using a flat low-sheath-flow interface. ELECTROPHORESIS. 29(24), 4938-4943, 2009. [JCR]　[WOS]
(Li Fu-An), Huang Ju-Li, Shen Shang-Yu, Wang Che-Wei, Her Guor-Rong*. Development of a Liquid-Junction/Low-Flow Interface for Phosphate Buffer Capillary Electrophoresis Mass Spectrometry. Analytical Chemistry. 81(7), 2810-2814, 2009. [JCR]　[WOS]
Chen Chao-Jung, (Li Fu-An), Her Guor-Rong*. Development of a low-flow multiplexed interface for capillary electrophoresis/electrospray ion trap mass spectrometry using sequential spray. ELECTROPHORESIS. 29(10), 1997-2003, 2008. [JCR]　[WOS]
(Li Fu-An), Wang Chih-Hung, Her Guor-Rong*. A sheathless poly(methyl methacrylate) chip-CE/MS interface fabricated using a wire-assisted epoxy-fixing method. ELECTROPHORESIS. 28(8), 1265-1273, 2007. [JCR]　[WOS]
Chien Chiu-Tang, (Li Fu-An), Huang Ju-Li, Her Guor-Rong*. CE-MS of antihistamines using nonvolatile phosphate buffer. ELECTROPHORESIS. 28(9), 1454-1460, 2007. [JCR]　[WOS]
(Li Fu-An), Wu Ming-Chi, Her Guor-Rong*. Development of a Multiplexed Interface for Capillary Electrophoresis−Electrospray Ion Trap Mass Spectrometry. Analytical Chemistry. 78(15), 5316-5321, 2006. [JCR]　[WOS]
Chao Bing-Fong, Chen Chao-Jung, (Li Fu-An), Her Guor-Rong*. Sheathless capillary electrophoresis-mass spectrometry using a pulsed electrospray ionization source. ELECTROPHORESIS. 27(11), 2083-2090, 2006. [JCR]　[WOS]

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