Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 張以承 Chang, Yi-Cheng

Journal 128

(Chang Yi-Cheng), Hsieh Meng-Lun, Lee Hsiao-Lin, Hee Siow-Wey, Chang Chi-Fon, Yen Hsin-Yung, Chen Yi-An, Chen Yet-Ran, Chou Ya-Wen, Li Fu-An, Ke Yi-Yu, Chen Shih-Yi, Hung Ming-Shiu, Hung Alfur Fu-Hsin, Huang Jing-Yong, Chiu Chu-Hsuan, Lin Shih-Yao, Shih Sheue-Fang, Hsu Chih-Neng, Hwang Juey-Jen, Yeh Teng-Kuang, Rachel Cheng Ting-Jen, Liao Karen Chia-Wen, Laio Daniel, Lin Shu-Wha, Chen Tzu-Yu, Hu Chun-Mei, Vogel Ulla, Saar Daniel, Kragelund Birthe B., Tsou Lun Kelvin, Tseng Yu-Hua, Chuang Lee-Ming. Identification of PTGR2 inhibitors as a new therapy for diabetes and obesity. EMBO MOLECULAR MEDICINE. , 2024-12-20.
Lin HH, Wu CY, Wang CG, Fu H, Chang CC, Chang YC, Huang YT. Association between body mass index and tuberculosis risk: analysis of pooled data from two cohorts. CLINICAL INFECTIOUS DISEASES. , . [JCR]
Wu Cyun-Ming, Li Hao-Yun, Li Wen-Yi, Hsu Chih-Neng, Yang Wei-Shun, Chuang Gwo-Tsang, Che Tony Pan-Hou, Lee Tung-Yuan, Lee Hsiao-Lin, Hee Siow-Wey, Lee Jiin-Horng, Liao Daniel, Liao Karen Chia-Wen, Liu Ya-Wen, Hsuan Chin-Feng, Chang Yi-Cheng, Chu Shao-Lun. Protocol to measure glucose utilization in mouse tissues using radiolabeled 2-deoxy-D-glucose. STAR Protocols. 5(4), 103478, 2024-12. [JCR]
Lin, H. H., Yu, I. S., Cheng, M. S., Chang, T. J., Lin, H. Y., (Chang, Y. C.), [...], Huang, H. P., Lee, M. S. Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA. NATURE COMMUNICATIONS. 15(1), 15-10537, 2024-12-03. [JCR]
Chuang Gwo-Tsann, Hsiung Chia-Ni, Che Tony Pan-Hou, Chang Yi-Cheng. Discovering Novel Loci of Chronic Kidney Disease via Principal Component Analysis-Based Multiple-Trait Genome-Wide Association Study. American Journal of Nephrology. Online ahead of print., 1-13, 2024-10-21. [JCR]
Liu Chia-Ju, Chen Jien-jiun, Wu Jo-Hsuan, Chung Yao-Te, Chen Jin-Wun, Liu Meng-Tsun, Chiu Chu-Hsuan, Chang Yi-Cheng, Chang Sheng-Nan, Lin Jou-Wei, Hwang Juey-Jen. Association of exosomes in patients with compromised myocardial perfusion on functional imaging. Journal of the Formosan Medical Association. 123(9), 968-974, 2024-09. [JCR]
Takahashi Nagahide, Nishimura Tomoko, Okumura Akemi, Harada Taeko, Iwabuchi Toshiki, Rahman Md Shafiur, Liu Pi-Hua, Chuang Gwo-Tsann, Chang Yi-Cheng, Nomura Yoko, Tsuchiya Kenji J. Association between genetic risk of melatonin secretion and attention deficit hyperactivity disorder. Psychiatry Research Communications. 4(3), 100188, 2024-07-30. [JCR]
Tsao Hsiao-Mei, Lai Tai-Shuan, (Chang Yi-Cheng), Hsiung Chia-Ni, Tsai I-Jung, Chou Yu-Hsiang, Wu Vin-Cent, Lin Shuei-Liong, Chen Yung-Ming. A multi-trait GWAS identifies novel genes influencing albuminuria. Nephrology Dialysis Transplantation. 40(1), 123-132, 2024-05-21. [JCR]
Keener R, [...], Chang YC, [...], Battle A. Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes. NATURE COMMUNICATIONS. 15(1), 15-4417, 2024-05-24. [JCR]
Hee Siow-Wey, Chang Yi-Cheng, Su Lynn, Chen Ing-Jung, Jeng Yung-Ming, Hsieh Meng-Lun, Chang Yu-Chia, Li Fu-An, Liao Daniel, Chen Shiau-Mei, Chuang Lee-Ming. 15-keto-PGE2 alleviates nonalcoholic steatohepatitis through its covalent modification of NF-κB factors. iScience. 26(10), 107997, 2023-10. [JCR]　[WOS]
Chang Yi-Cheng, Lee Hsiao-Lin, Yang Wenjin, Hsieh Meng-Lun, Liu Cai-Cin, Lee Tung-Yuan, Huang Jing-Yong, Nong Jiun-Yi, Li Fu-An, Chuang Hsiao-Li, Ding Zhi-Zhong, Su Wei-Lun, Chueh Li-Yun, Tsai Yi-Ting, Chen Che-Hong, Mochly-Rosen Daria, Chuang Lee-Ming. A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators. Nature Communications. 14(1), 1-16, 2023-09-25. [JCR]　[WOS]
Recto K, Kachroo P, Huan T, Van Den Berg D, Lee GY, Bui H, Lee DH, Gereige J, Yao C, Hwang SJ, Joehanes R, Weiss ST; NHLBI Trans-Omics in Precision Medicine (TOPMed) Consortium; O'Connor GT, Levy D, DeMeo DL. Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma. EBIOMEDICINE. 95, 1-13, 2023-08-17.
Chang Yi-Cheng, Hsu Chih-Neng, Chong Keong, Yang Po-Jen, Ser Kong-Han, Lee Po-Chu, Chen Shu-Chun, Hsuan Chin-Feng, Lee Yi-Chih, Hsu Chih-Cheng, Lee Hsiao-Lin, Liao Karen Chia-Wen, Hsieh Meng-Lun, Chuang Gwo-Tsann, Yang Wei-Shun, Chu Shao-Lun, Li Wen-Yi, Chuang Lee-Ming, Lee Wei-Jei. Roux-en-Y and One-Anastomosis Gastric Bypass Surgery Are Superior to Sleeve Gastrectomy in Lowering Glucose and Cholesterol Levels Independent of Weight Loss: a Propensity-Score Weighting Analysis. Obesity Surgery. 33(10), 3035-3050, 2023-08-24. [JCR]　[WOS]
Yang Wei-shun, Chuang Gwo-Tsann, Che Tony Pan-Hou, Chueh Li-Yun, Li Wen-Yi, Hsu Chih-Neng, Hsiung Chia-Ni, Ku Hsiao-Chia, Lin Yi-Ching, Chen Yi-Shun, Hee Siow-Wey, Chang Tien-Jyun, Chen Shiau-Mei, Hsieh Meng-Lun, Lee Hsiao-Lin, Liao Karen Chia-Wen, Shen Chen-Yang, Chang Yi-Cheng. Genome-Wide Association Studies for Albuminuria of Nondiabetic Taiwanese Population. American Journal of Nephrology. Online publication, 1-11, 2023-07-12. [JCR]　[WOS]
Williamson Alice, Norris Dougall M., Yin Xianyong, Broadaway K. Alaine, Moxley Anne H., Vadlamudi Swarooparani, Wilson Emma P., Jackson Anne U., Ahuja Vasudha, Andersen Mette K., Arzumanyan Zorayr, Bonnycastle Lori L., Bornstein Stefan R., Bretschneider Maxi P., Buchanan Thomas A., Chang Yi-Cheng, Chuang Lee-Ming, Chung Ren-Hua, Clausen Tine D., Damm Peter, Delgado Graciela E., de Mello Vanessa D., Dupuis Josée, Dwivedi Om P., Erdos Michael R., Silva Lilian Fernandes, Frayling Timothy M., Gieger Christian, Goodarzi Mark O., Guo Xiuqing, Gustafsson Stefan, Hakaste Liisa, Hammar Ulf, Hatem Gad, Herrmann Sandra, Højlund Kurt, Horn Katrin, Hsueh Willa A., Hung Yi-Jen, Hwu Chii-Min, Jonsson Anna, Kårhus Line L., Kleber Marcus E., Kovacs Peter, Lakka Timo A., Lauzon Marie, Lee I-Te, Lindgren Cecilia M., Lindström Jaana, Linneberg Allan, Liu Ching-Ti, Luan Jian’an, Aly Dina Mansour, Mathiesen Elisabeth, Moissl Angela P., Morris Andrew P., Narisu Narisu, Perakakis Nikolaos, Peters Annette, Prasad Rashmi B., Rodionov Roman N., Roll Kathryn, Rundsten Carsten F., Sarnowski Chloé, Savonen Kai, Scholz Markus, Sharma Sapna, Stinson Sara E., Suleman Sufyan, Tan Jingyi, Taylor Kent D., Uusitupa Matti, Vistisen Dorte, Witte Daniel R., Walther Romy, Wu Peitao, Xiang Anny H., Zethelius Björn, de Mello Vanessa D., Ahlqvist Emma, Bergman Richard N., Chen Yii-Der Ida, Collins Francis S., Fall Tove, Florez Jose C., Fritsche Andreas, Grallert Harald, Groop Leif, Hansen Torben, Koistinen Heikki A., Komulainen Pirjo, Laakso Markku, Lind Lars, Loeffler Markus, März Winfried, Meigs James B., Raffel Leslie J., Rauramaa Rainer, Rotter Jerome I., Schwarz Peter E. H., Stumvoll Michael, Sundström Johan, Tönjes Anke, Tuomi Tiinamaija, Tuomilehto Jaakko, Wagner Robert, Barroso Inês, Walker Mark, Grarup Niels, Boehnke Michael, Wareham Nicholas J., Mohlke Karen L., Wheeler Eleanor, O’Rahilly Stephen, Fazakerley Daniel J., Langenberg Claudia, . Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake. Nature Genetics. 55(6), 973-983, 2023-06. [JCR]　[WOS]
Weinstock JS, [...] NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; (Chang YC), [...] Jaiswal S. Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis. Nature. 616(7958), 755-763, 2023-04-12. [JCR]
Hsuan Chin-Feng, Teng Sean I. F., Hsu Chih-Neng, Liao Daniel, Chang Allen Jiun-Wei, Lee Hsiao-Lin, Hee Siow-Wey, Chang Yi-Cheng, Chuang Lee-Ming. Emerging Therapy for Diabetic Cardiomyopathy: From Molecular Mechanism to Clinical Practice. Biomedicines. 11(3), 662, 2023-02-22. [JCR]　[WOS]
Lu JY, Ou HY, Wu CZ, Yang CY, Jiang JY, Lu CH, Jiang YD, Chang TJ, Chang YC, Hsieh ML, Wu WC, Li HY, Du YF, Lin CH, Hung HC, Tien KJ, Yeh NC, Lee SY, Yu HI, Chuang LM. A randomized trial on the effect of transcutaneous electrical nerve stimulator on glycemic control in patients with type 2 diabetes. Scientific reports. 13(1), 2662, 2023. [JCR]　[WOS]
Chiu CH, Hsuan CF, Lin SH, Hung YJ, Hwu CM, Hee SW, Lin SW, Fong SW, Hsieh PC, Yang WS, Lin WC, Lee HL, Hsieh ML, Li WY, Lin JW, Hsu CN, Wu VC, Chuang GT, Chang YC, Chuang LM. ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking. Journal of biomedical science. 30(1), 13, 2023. [JCR]　[WOS]
Laiman J, Hsu YJ, Loh J, Tang WC, Chuang MC, Liu HK, Yang WS, Chen BC, Chuang LM, Chang YC, Liu YW. GSK3alpha phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells. The Journal of cell biology. 222(2), e202102119, 2023. [JCR]　[WOS]
Tsao HM, Lai TS, Chang YC, Hsiung CN, Chou YH, Wu VC, Lin SL, Chen YM. Serum Urate and Risk of Chronic Kidney Disease: A Mendelian Randomization Study Using Taiwan Biobank. Mayo Clinic proceedings. S0025-6196(23), 23, 2023. [JCR]　[WOS]
Liu PH, Chuang GT, Hsiung CN, Yang WS, Ku HC, Lin YC, Chen YS, Huang YY, Lin CH, Li WY, Lin JW, Hsu CN, Hwang JJ, Liao KC, Hsieh ML, Lee HL, Shen CY, Chang YC. A genome-wide association study for melatonin secretion. Scientific reports. 12(1), 8025, 2022. [JCR]　[WOS]
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen SH, Ferreira T, Highland HH, Ji Y, Karaderi T, Lin K, Lull K, Malden DE, Medina-Gomez C, Machado M, Moore A, Rueger S, Sim X, Vrieze S, Ahluwalia TS, Akiyama M, Allison MA, Alvarez M, Andersen MK, Ani A, Appadurai V, Arbeeva L, Bhaskar S, Bielak LF, Bollepalli S, Bonnycastle LL, Bork-Jensen J, Bradfield JP, Bradford Y, Braund PS, Brody JA, Burgdorf KS, Cade BE, Cai H, Cai Q, Campbell A, Canadas-Garre M, Catamo E, Chai JF, Chai X, Chang LC, Chang YC, Chen CH, Chesi A, Choi SH, Chung RH, Cocca M, Concas MP, Couture C, Cuellar-Partida G, Danning R, Daw EW, Degenhard F, Delgado GE, Delitala A, Demirkan A, Deng X, Devineni P, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Ekici AB, Engmann JE, Fairhurst-Hunter Z, Farmaki AE, Faul JD, Fernandez-Lopez JC, Forer L, Francescatto M, Freitag-Wolf S, Fuchsberger C, Galesloot TE, Gao Y, Gao Z, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, He J, Heard-Costa N, Hebbar P, Hindy G, Ho YA, Hofer E, Holliday E, Horn K, Hornsby WE, Hottenga JJ, Huang H, Huang J, Huerta-Chagoya A, Huffman JE, Hung YJ, Huo S, Hwang MY, Iha H, Ikeda DD, Isono M, Jackson AU, Jager S, Jansen IE, Johansson I, Jonas JB, Jonsson A, Jorgensen T, Kalafati IP, Kanai M, Kanoni S, Karhus LL, Kasturiratne A, Katsuya T, Kawaguchi T, Kember RL, Kentistou KA, Kim HN, Kim YJ, Kleber ME, Knol MJ, Kurbasic A, Lauzon M, Le P, Lea R, Lee JY, Leonard HL, Li SA, Li X, Li X, Liang J, Lin H, Lin SY, Liu J, Liu X, Lo KS, Long J, Lores-Motta L, Luan J, Lyssenko V, Lyytikainen LP, Mahajan A, Mamakou V, Mangino M, Manichaikul A, Marten J, Mattheisen M, Mavarani L, McDaid AF, Meidtner K, Melendez TL, Mercader JM, Milaneschi Y, Miller JE, Millwood IY, Mishra PP, Mitchell RE, Mollehave LT, Morgan A, Mucha S, Munz M, Nakatochi M, Nelson CP, Nethander M, Nho CW, Nielsen AA, Nolte IM, Nongmaithem SS, Noordam R, Ntalla I, Nutile T, Pandit A, Christofidou P, Parna K, Pauper M, Petersen ERB, Petersen LV, Pitkanen N, Polasek O, Poveda A, Preuss MH, Pyarajan S, Raffield LM, Rakugi H, Ramirez J, Rasheed A, Raven D, Rayner NW, Riveros C, Rohde R, Ruggiero D, Ruotsalainen SE, Ryan KA, Sabater-Lleal M, Saxena R, Scholz M, Sendamarai A, Shen B, Shi J, Shin JH, Sidore C, Sitlani CM, Slieker RC, Smit RAJ, Smith AV, Smith JA, Smyth LJ, Southam L, Steinthorsdottir V, Sun L, Takeuchi F, Tallapragada DSP, Taylor KD, Tayo BO, Tcheandjieu C, Terzikhan N, Tesolin P, Teumer A, Theusch E, Thompson DJ, Thorleifsson G, Timmers PRHJ, Trompet S, Turman C, Vaccargiu S, van der Laan SW, van der Most PJ, van Klinken JB, van Setten J, Verma SS, Verweij N, Veturi Y, Wang CA, Wang C, Wang L, Wang Z, Warren HR, Bin Wei W, Wickremasinghe AR, Wielscher M, Wiggins KL, Winsvold BS, Wong A, Wu Y, Wuttke M, Xia R, Xie T, Yamamoto K, Yang J, Yao J, Young H, Yousri NA, Yu L, Zeng L, Zhang W, Zhang X, Zhao JH, Zhao W, Zhou W, Zimmermann ME, Zoledziewska M, Adair LS, Adams HHH, Aguilar-Salinas CA, Al-Mulla F, Arnett DK, Asselbergs FW, Asvold BO, Attia J, Banas B, Bandinelli S, Bennett DA, Bergler T, Bharadwaj D, Biino G, Bisgaard H, Boerwinkle E, Boger CA, Bonnelykke K, Boomsma DI, Borglum AD, Borja JB, Bouchard C, Bowden DW, Brandslund I, Brumpton B, Buring JE, Caulfield MJ, Chambers JC, Chandak GR, Chanock SJ, Chaturvedi N, Chen YI, Chen Z, Cheng CY, Christophersen IE, Ciullo M, Cole JW, Collins FS, Cooper RS, Cruz M, Cucca F, Cupples LA, Cutler MJ, Damrauer SM, Dantoft TM, de Borst GJ, de Groot LCPGM, De Jager PL, de Kleijn DPV, Janaka de Silva H, Dedoussis GV, den Hollander AI, Du S, Easton DF, Elders PJM, Eliassen AH, Ellinor PT, Elmstahl S, Erdmann J, Evans MK, Fatkin D, Feenstra B, Feitosa MF, Ferrucci L, Ford I, Fornage M, Franke A, Franks PW, Freedman BI, Gasparini P, Gieger C, Girotto G, Goddard ME, Golightly YM, Gonzalez-Villalpando C, Gordon-Larsen P, Grallert H, Grant SFA, Grarup N, Griffiths L, Gudnason V, Haiman C, Hakonarson H, Hansen T, Hartman CA, Hattersley AT, Hayward C, Heckbert SR, Heng CK, Hengstenberg C, Hewitt AW, Hishigaki H, Hoyng CB, Huang PL, Huang W, Hunt SC, Hveem K, Hypponen E, Iacono WG, Ichihara S, Ikram MA, Isasi CR, Jackson RD, Jarvelin MR, Jin ZB, Jockel KH, Joshi PK, Jousilahti P, Jukema JW, Kahonen M, Kamatani Y, Kang KD, Kaprio J, Kardia SLR, Karpe F, Kato N, Kee F, Kessler T, Khera AV, Khor CC, Kiemeney LALM, Kim BJ, Kim EK, Kim HL, Kirchhof P, Kivimaki M, Koh WP, Koistinen HA, Kolovou GD, Kooner JS, Kooperberg C, Kottgen A, Kovacs P, Kraaijeveld A, Kraft P, Krauss RM, Kumari M, Kutalik Z, Laakso M, Lange LA, Langenberg C, Launer LJ, Le Marchand L, Lee H, Lee NR, Lehtimaki T, Li H, Li L, Lieb W, Lin X, Lind L, Linneberg A, Liu CT, Liu J, Loeffler M, London B, Lubitz SA, Lye SJ, Mackey DA, Magi R, Magnusson PKE, Marcus GM, Vidal PM, Martin NG, Marz W, Matsuda F, McGarrah RW, McGue M, McKnight AJ, Medland SE, Mellstrom D, Metspalu A, Mitchell BD, Mitchell P, Mook-Kanamori DO, Morris AD, Mucci LA, Munroe PB, Nalls MA, Nazarian S, Nelson AE, Neville MJ, Newton-Cheh C, Nielsen CS, Nothen MM, Ohlsson C, Oldehinkel AJ, Orozco L, Pahkala K, Pajukanta P, Palmer CNA, Parra EJ, Pattaro C, Pedersen O, Pennell CE, Penninx BWJH, Perusse L, Peters A, Peyser PA, Porteous DJ, Posthuma D, Power C, Pramstaller PP, Province MA, Qi Q, Qu J, Rader DJ, Raitakari OT, Ralhan S, Rallidis LS, Rao DC, Redline S, Reilly DF, Reiner AP, Rhee SY, Ridker PM, Rienstra M, Ripatti S, Ritchie MD, Roden DM, Rosendaal FR, Rotter JI, Rudan I, Rutters F, Sabanayagam C, Saleheen D, Salomaa V, Samani NJ, Sanghera DK, Sattar N, Schmidt B, Schmidt H, Schmidt R, Schulze MB, Schunkert H, Scott LJ, Scott RJ, Sever P, Shiroma EJ, Shoemaker MB, Shu XO, Simonsick EM, Sims M, Singh JR, Singleton AB, Sinner MF, Smith JG, Snieder H, Spector TD, Stampfer MJ, Stark KJ, Strachan DP, 't Hart LM, Tabara Y, Tang H, Tardif JC, Thanaraj TA, Timpson NJ, Tonjes A, Tremblay A, Tuomi T, Tuomilehto J, Tusie-Luna MT, Uitterlinden AG, van Dam RM, van der Harst P, Van der Velde N, van Duijn CM, van Schoor NM, Vitart V, Volker U, Vollenweider P, Volzke H, Wacher-Rodarte NH, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Weir DR, Werge TM, Widen E, Wilkens LR, Willemsen G, Willett WC, Wilson JF, Wong TY, Woo JT, Wright AF, Wu JY, Xu H, Yajnik CS, Yokota M, Yuan JM, Zeggini E, Zemel BS, Zheng W, Zhu X, Zmuda JM, Zonderman AB, Zwart JA, Chasman DI, Cho YS, Heid IM, McCarthy MI, Ng MCY, O'Donnell CJ, Rivadeneira F, Thorsteinsdottir U, Sun YV, Tai ES, Boehnke M, Deloukas P, Justice AE, Lindgren CM, Loos RJF, Mohlke KL, North KE, Stefansson K, Walters RG, Winkler TW, Young KL, Loh PR, Yang J, Esko T, Assimes TL, Auton A, Abecasis GR, Willer CJ, Locke AE, Berndt SI, Lettre G, Frayling TM, Okada Y, Wood AR, Visscher PM, Hirschhorn JN. A saturated map of common genetic variants associated with human height. Nature. 610(7933), 704-712, 2022. [JCR]　[WOS]
Wainschtein P, Jain D, Zheng Z, Cupples LA, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, Liu CT, Albert CM, Roden D, Chasman DI, Darbar D, Lloyd-Jones DM, Arnett DK, Regan EA, Boerwinkle E, Rotter JI, O'Connell JR, Yanek LR, de Andrade M, Allison MA, McDonald MN, Chung MK, Fornage M, Chami N, Smith NL, Ellinor PT, Vasan RS, Mathias RA, Loos RJF, Rich SS, Lubitz SA, Heckbert SR, Redline S, Guo X, Chen Y-I, Laurie CA, Hernandez RD, McGarvey ST, Goddard ME, Laurie CC, North KE, Lange LA, Weir BS, Yengo L, Yang J, Visscher PM. Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. Nature genetics. 54(3), 263-273, 2022. [JCR]　[WOS]
Lin CH, Lai YC, Chang TJ, Jiang YD, Chang YC, Chuang LM. Hemoglobin glycation index predicts renal function deterioration in patients with type 2 diabetes and a low risk of chronic kidney disease. Diabetes research and clinical practice. 186, 109834, 2022. [JCR]　[WOS]
Sharma A, Razaghizad A, Ferreira JP, Machu JL, Bozec E, Girerd N, Rossignol P, Zannad F. Metabolic Syndrome and the Risk of Preclinical Heart Failure: Insights after 17 Years of Follow-Up from the STANISLAS Cohort. Cardiology. 147(3), 281-287, 2022. [JCR]　[WOS]
Lin CS, Chang CC, Yeh CC, Chang YC, Chen TL, Liao CC. Outcomes following diabetes admission in patients who had influenza vaccination: A population-based cohort study. Diabetes research and clinical practice. 189, 109930, 2022. [JCR]　[WOS]
Jia Y, Li D, Yu J, Jiang W, Liao X, Zhao Q. Potential diabetic cardiomyopathy therapies targeting pyroptosis: A mini review. Frontiers in cardiovascular medicine. 9, 985020, 2022. [JCR]　[WOS]
Ko TH, Chang YC, Chang CH, Liao KC, Magee MJ, Lin HH. Prediabetes and risk of active tuberculosis: a cohort study from Northern Taiwan. International journal of epidemiology. dyac214, dyac214, 2022. [JCR]　[WOS]
Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, Selvaraj MS, Zhang D, Park J, Aguilar-Salinas CA, Antonacci-Fulton L, Ardissino D, Arnett DK, Aslibekyan S, Atzmon G, Ballantyne CM, Barajas-Olmos F, Barzilai N, Becker LC, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Bowden DW, Bown MJ, Brody JA, Broome JG, Burtt NP, Cade BE, Centeno-Cruz F, Chan E, Chang YC, Chen YI, Cheng CY, Choi WJ, Chowdhury R, Contreras-Cubas C, Cordova EJ, Correa A, Cupples LA, Curran JE, Danesh J, de Vries PS, DeFronzo RA, Doddapaneni H, Duggirala R, Dutcher SK, Ellinor PT, Emery LS, Florez JC, Fornage M, Freedman BI, Fuster V, Garay-Sevilla ME, Garcia-Ortiz H, Germer S, Gibbs RA, Gieger C, Glaser B, Gonzalez C, Gonzalez-Villalpando ME, Graff M, Graham SE, Grarup N, Groop LC, Guo X, Gupta N, Han S, Hanis CL, Hansen T, He J, Heard-Costa NL, Hung YJ, Hwang MY, Irvin MR, Islas-Andrade S, Jarvik GP, Kang HM, Kardia SLR, Kelly T, Kenny EE, Khan AT, Kim BJ, Kim RW, Kim YJ, Koistinen HA, Kooperberg C, Kuusisto J, Kwak SH, Laakso M, Lange LA, Lee J, Lee J, Lee S, Lehman DM, Lemaitre RN, Linneberg A, Liu J, Loos RJF, Lubitz SA, Lyssenko V, Ma RCW, Martin LW, Martinez-Hernandez A, Mathias RA, McGarvey ST, McPherson R, Meigs JB, Meitinger T, Melander O, Mendoza-Caamal E, Metcalf GA, Mi X, Mohlke KL, Montasser ME, Moon JY, Moreno-Macias H, Morrison AC, Muzny DM, Nelson SC, Nilsson PM, O'Connell JR, Orho-Melander M, Orozco L, Palmer CNA, Palmer ND, Park CJ, Park KS, Pedersen O, Peralta JM, Peyser PA, Post WS, Preuss M, Psaty BM, Qi Q, Rao DC, Redline S, Reiner AP, Revilla-Monsalve C, Rich SS, Samani N, Schunkert H, Schurmann C, Seo D, Seo JS, Sim X, Sladek R, Small KS, So WY, Stilp AM, Tai ES, Tam CHT, Taylor KD, Teo YY, Thameem F, Tomlinson B, Tsai MY, Tuomi T, Tuomilehto J, Tusie-Luna T, Udler MS, van Dam RM, Vasan RS, Viaud Martinez KA, Wang FF, Wang X, Watkins H, Weeks DE, Wilson JG, Witte DR, Wong TY, Yanek LR, Kathiresan S, Rader DJ, Rotter JI, Boehnke M, McCarthy MI, Willer CJ, Natarajan P, Flannick JA, Khera AV, Peloso GM. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. American journal of human genetics. 109(1), 81-96, 2022. [JCR]　[WOS]
He KY, Kelly TN, Wang H, Liang J, Zhu L, Cade BE, Assimes TL, Becker LC, Beitelshees AL, Bielak LF, Bress AP, Brody JA, Chang YC, Chang YC, de Vries PS, Duggirala R, Fox ER, Franceschini N, Furniss AL, Gao Y, Guo X, Haessler J, Hung YJ, Hwang SJ, Irvin MR, Kalyani RR, Liu CT, Liu C, Martin LW, Montasser ME, Muntner PM, Mwasongwe S, Naseri T, Palmas W, Reupena MS, Rice KM, Sheu WH, Shimbo D, Smith JA, Snively BM, Yanek LR, Zhao W, Blangero J, Boerwinkle E, Chen YI, Correa A, Cupples LA, Curran JE, Fornage M, He J, Hou L, Kaplan RC, Kardia SLR, Kenny EE, Kooperberg C, Lloyd-Jones D, Loos RJF, Mathias RA, McGarvey ST, Mitchell BD, North KE, Peyser PA, Psaty BM, Raffield LM, Rao DC, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Tracy R, Vasan RS, Morrison AC, Levy D, Chakravarti A, Arnett DK, Zhu X. Rare coding variants in RCN3 are associated with blood pressure. BMC genomics. 23(1), 148, 2022. [JCR]　[WOS]
Lin CH, Lai YC, Chang TJ, Jiang YD, Chang YC, Chuang LM. Visit-to-visit variability in albuminuria predicts renal function deterioration in patients with type 2 diabetes. Journal of diabetes investigation. 13(6), 1021-1029, 2022. [JCR]　[WOS]
Sofer Tamar, Zheng Xiuwen, Laurie Cecelia A., Gogarten Stephanie M., Brody Jennifer A., Conomos Matthew P., Bis Joshua C., Thornton Timothy A., Szpiro Adam, O’Connell Jeffrey R., Lange Ethan M., Gao Yan, Cupples L. Adrienne, Psaty Bruce M., Abe Namiko, Abecasis Gonçalo, Aguet Francois, Albert Christine, Almasy Laura, Alonso Alvaro, Ament Seth, Anderson Peter, Anugu Pramod, Applebaum-Bowden Deborah, Ardlie Kristin, Arking Dan, Arnett Donna K., Ashley-Koch Allison, Aslibekyan Stella, Assimes Tim, Auer Paul, Avramopoulos Dimitrios, Ayas Najib, Balasubramanian Adithya, Barnard John, Barnes Kathleen, Barr R. Graham, Barron-Casella Emily, Barwick Lucas, Beaty Terri, Beck Gerald, Becker Diane, Becker Lewis, Beer Rebecca, Beitelshees Amber, Benjamin Emelia, Benos Takis, Bezerra Marcos, Bielak Larry, Bis Joshua, Blackwell Thomas, Blangero John, Boerwinkle Eric, Bowden Donald W., Bowler Russell, Brody Jennifer, Broeckel Ulrich, Broome Jai, Brown Deborah, Bunting Karen, Burchard Esteban, Bustamante Carlos, Buth Erin, Cade Brian, Cardwell Jonathan, Carey Vincent, Carrier Julie, Carty Cara, Casaburi Richard, Romero Juan P. Casas, Casella James, Castaldi Peter, Chaffin Mark, Chang Christy, Chang Yi-Cheng, Chasman Daniel, Chavan Sameer, Chen Bo-Juen, Chen Wei-Min, Chen Yii-Der Ida, Cho Michael, Choi Seung Hoan, Chuang Lee-Ming, Chung Mina, Chung Ren-Hua, Clish Clary, Comhair Suzy, Conomos Matthew, Cornell Elaine, Correa Adolfo, Crandall Carolyn, Crapo James, Cupples L. Adrienne, Curran Joanne, Curtis Jeffrey, Custer Brian, Damcott Coleen, Darbar Dawood, David Sean, Davis Colleen, Daya Michelle, de Andrade Mariza, Fuentes Lisa de las, de Vries Paul, DeBaun Michael, Deka Ranjan, DeMeo Dawn, Devine Scott, Dinh Huyen, Doddapaneni Harsha, Duan Qing, Dugan-Perez Shannon, Duggirala Ravi, Durda Jon Peter, Dutcher Susan K., Eaton Charles, Ekunwe Lynette, El Boueiz Adel, Ellinor Patrick, Emery Leslie, Erzurum Serpil, Farber Charles, Farek Jesse, Fingerlin Tasha, Flickinger Matthew, Fornage Myriam, Franceschini Nora, Frazar Chris, Fu Mao, Fullerton Stephanie M., Fulton Lucinda, Gabriel Stacey, Gan Weiniu, Gao Shanshan, Gao Yan, Gass Margery, Geiger Heather, Gelb Bruce, Geraci Mark, Germer Soren, Gerszten Robert, Ghosh Auyon, Gibbs Richard, Gignoux Chris, Gladwin Mark, Glahn David, Gogarten Stephanie, Gong Da-Wei, Goring Harald, Graw Sharon, Gray Kathryn J., Grine Daniel, Gross Colin, Gu C. Charles, Guan Yue, Guo Xiuqing, Gupta Namrata, Haas David M., Haessler Jeff, Hall Michael, Han Yi, Hanly Patrick, Harris Daniel, Hawley Nicola L., He Jiang, Heavner Ben, Heckbert Susan, Hernandez Ryan, Herrington David, Hersh Craig, Hidalgo Bertha, Hixson James, Hobbs Brian, Hokanson John, Hong Elliott, Hoth Karin, Hsiung Chao, Hu Jianhong, Hung Yi-Jen, Huston Haley, Hwu Chii Min, Irvin Marguerite Ryan, Jackson Rebecca, Jain Deepti, Jaquish Cashell, Johnsen Jill, Johnson Andrew, Johnson Craig, Johnston Rich, Jones Kimberly, Kang Hyun Min, Kaplan Robert, Kardia Sharon, Kelly Shannon, Kenny Eimear, Kessler Michael, Khan Alyna, Khan Ziad, Kim Wonji, Kimoff John, Kinney Greg, Konkle Barbara, Kooperberg Charles, Kramer Holly, Lange Christoph, Lange Ethan, Lange Leslie, Laurie Cathy, Laurie Cecelia, LeBoff Meryl, Lee Sandra, Lee Wen-Jane, LeFaive Jonathon, Levine David, Levy Dan, Lewis Joshua, Li Xiaohui, Li Yun, Lin Henry, Lin Honghuang, Lin Xihong, Liu Simin, Liu Yongmei, Liu Yu, Loos Ruth J. F., Lubitz Steven, Lunetta Kathryn, Luo James, Magalang Ulysses, Mahaney Michael, Make Barry, Manichaikul Ani, Manning Alisa, Manson JoAnn, Martin Lisa, Marton Melissa, Mathai Susan, Mathias Rasika, May Susanne, McArdle Patrick, McDonald Merry-Lynn, McFarland Sean, McGarvey Stephen, McGoldrick Daniel, McHugh Caitlin, McNeil Becky, Mei Hao, Meigs James, Menon Vipin, Mestroni Luisa, Metcalf Ginger, Meyers Deborah A., Mignot Emmanuel, Mikulla Julie, Min Nancy, Minear Mollie, Minster Ryan L., Mitchell Braxton D., Moll Matt, Momin Zeineen, Montasser May E., Montgomery Courtney, Muzny Donna, Mychaleckyj Josyf C., Nadkarni Girish, Naik Rakhi, Naseri Take, Natarajan Pradeep, Nekhai Sergei, Nelson Sarah C., Neltner Bonnie, Nessner Caitlin, Nickerson Deborah, Nkechinyere Osuji, North Kari, O’Connell Jeff, O’Connor Tim, Ochs-Balcom Heather, Okwuonu Geoffrey, Pack Allan, Paik David T., Palmer Nicholette, Pankow James, Papanicolaou George, Parker Cora, Peloso Gina, Peralta Juan Manuel, Perez Marco, Perry James, Peters Ulrike, Peyser Patricia, Phillips Lawrence S., Pleiness Jacob, Pollin Toni, Post Wendy, Becker Julia Powers, Boorgula Meher Preethi, Preuss Michael, Psaty Bruce, Qasba Pankaj, Qiao Dandi, Qin Zhaohui, Rafaels Nicholas, Raffield Laura, Rajendran Mahitha, Ramachandran Vasan S., Rao D. C., Rasmussen-Torvik Laura, Ratan Aakrosh, Redline Susan, Reed Robert, Reeves Catherine, Regan Elizabeth, Reiner Alex, Reupena Muagututi’a Sefuiva, Rice Ken, Rich Stephen, Robillard Rebecca, Robine Nicolas, Roden Dan, Roselli Carolina, Rotter Jerome, Ruczinski Ingo, Runnels Alexi, Russell Pamela, Ruuska Sarah, Ryan Kathleen, Sabino Ester Cerdeira, Saleheen Danish, Salimi Shabnam, Salvi Sejal, Salzberg Steven, Sandow Kevin, Sankaran Vijay G., Santibanez Jireh, Schwander Karen, Schwartz David, Sciurba Frank, Seidman Christine, Seidman Jonathan, Sériès Frédéric, Sheehan Vivien, Sherman Stephanie L., Shetty Amol, Shetty Aniket, Sheu Wayne Hui-Heng, Shoemaker M. Benjamin, Silver Brian, Silverman Edwin, Skomro Robert, Smith Albert Vernon, Smith Jennifer, Smith Josh, Smith Nicholas, Smith Tanja, Smoller Sylvia, Snively Beverly, Snyder Michael, Sofer Tamar, Sotoodehnia Nona, Stilp Adrienne M., Storm Garrett, Streeten Elizabeth, Su Jessica Lasky, Sung Yun Ju, Sylvia Jody, Szpiro Adam, Taliun Daniel, Tang Hua, Taub Margaret, Taylor Kent D., Taylor Matthew, Taylor Simeon, Telen Marilyn, Thornton Timothy A., Threlkeld Machiko, Tinker Lesley, Tirschwell David, Tishkoff Sarah, Tiwari Hemant, Tong Catherine, Tracy Russell, Tsai Michael, Vaidya Dhananjay, Van Den Berg David, VandeHaar Peter, Vrieze Scott, Walker Tarik, Wallace Robert, Walts Avram, Wang Fei Fei, Wang Heming, Wang Jiongming, Watson Karol, Watt Jennifer, Weeks Daniel E., Weinstock Joshua, Weir Bruce, Weiss Scott T., Weng Lu-Chen, Wessel Jennifer, Willer Cristen, Williams Kayleen, Williams L. Keoki, Wilson Carla, Wilson James, Winterkorn Lara, Wong Quenna, Wu Joseph, Xu Huichun, Yanek Lisa, Yang Ivana, Yu Ketian, Zekavat Seyedeh Maryam, Zhang Yingze, Zhao Snow Xueyan, Zhao Wei, Zhu Xiaofeng, Zody Michael, Zoellner Sebastian, Rice Kenneth M., . Variant-specific inflation factors for assessing population stratification at the phenotypic variance level. Nature Communications. 12(1), 3506, 2021-06-09. [JCR]　[WOS]
Luo Y, Kanai M, Choi W, Li X, Sakaue S, Yamamoto K, Ogawa K, Gutierrez-Arcelus M, Gregersen PK, Stuart PE, Elder JT, Forer L, Schonherr S, Fuchsberger C, Smith AV, Fellay J, Carrington M, Haas DW, Guo X, Palmer ND, Chen YI, Rotter JI, Taylor KD, Rich SS, Correa A, Wilson JG, Kathiresan S, Cho MH, Metspalu A, Esko T, Okada Y, Han B, McLaren PJ, Raychaudhuri S. A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. Nature genetics. 53(10), 1504-1516, 2021. [JCR]　[WOS]
Lee Hsiao-Lin, Hee Siow-Wey, Hsuan Chin-Feng, Yang Wenjin, Huang Jing-Yong, Lin Ya-Ling, Hsu Chih-Neng, Hwang Juey-Jen, Chen Shiau-Mei, Ding Zhi-Zhong, Lee Tung-Yuan, Lin Yu-Chiao, Tsai Feng-Chiao, Su Wei-Lun, Chueh Li-Yun, Hsieh Meng-Lun, Chen Che-Hong, Mochly-Rosen Daria, Chang Yi-Cheng, Chuang Lee-Ming. A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice. Antioxidants. 10(3), 450, 2021. [JCR]　[WOS]
Chang SN, Chen JJ, Wu JH, Chung YT, Chen JW, Chiu CH, Liu CJ, Liu MT, Chang YC, Li C, Lin JW, Hwang JJ, Lien WP. Association between Exosomal miRNAs and Coronary Artery Disease by Next-Generation Sequencing. Cells. 11(1), 98, 2021. [JCR]　[WOS]
Natarajan P, Pampana A, Graham SE, Ruotsalainen SE, Perry JA, de Vries PS, Broome JG, Pirruccello JP, Honigberg MC, Aragam K, Wolford B, Brody JA, Antonacci-Fulton L, Arden M, Aslibekyan S, Assimes TL, Ballantyne CM, Bielak LF, Bis JC, Cade BE, Do R, Doddapaneni H, Emery LS, Hung YJ, Irvin MR, Khan AT, Lange L, Lee J, Lemaitre RN, Martin LW, Metcalf G, Montasser ME, Moon JY, Muzny D, O'Connell JR, Palmer ND, Peralta JM, Peyser PA, Stilp AM, Tsai M, Wang FF, Weeks DE, Yanek LR, Wilson JG, Abecasis G, Arnett DK, Becker LC, Blangero J, Boerwinkle E, Bowden DW, Chang YC, Chen YI, Choi WJ, Correa A, Curran JE, Daly MJ, Dutcher SK, Ellinor PT, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, He J, Hveem K, Jarvik GP, Kaplan RC, Kardia SLR, Kenny E, Kim RW, Kooperberg C, Laurie CC, Lee S, Lloyd-Jones DM, Loos RJF, Lubitz SA, Mathias RA, Martinez KAV, McGarvey ST, Mitchell BD, Nickerson DA, North KE, Palotie A, Park CJ, Psaty BM, Rao DC, Redline S, Reiner AP, Seo D, Seo JS, Smith AV, Tracy RP, Vasan RS, Kathiresan S, Cupples LA, Rotter JI, Morrison AC, Rich SS, Ripatti S, Willer C, Peloso GM. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. Nature communications. 12(1), 2182, 2021. [JCR]　[WOS]
Shen PW, Ho CT, Hsiao SH, Chou YT, Chang YC, Liu JJ. Disruption of Cytosolic Folate Integrity Aggravates Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Modulates Metastatic Properties in Non-Small-Cell Lung Cancer Cells. International journal of molecular sciences. 22(16), 8838, 2021. [JCR]　[WOS]
Reiner AP, Raffield LM, Franceschini N, Auer PL, Lange EM, Nickerson DA, Zakai NA, Correa A, Olson N. Effect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans. Clinical journal of the American Society of Nephrology : CJASN. 16(2), 287-289, 2021. [JCR]　[WOS]
Keramati AR, Chen MH, Rodriguez BAT, Yanek LR, Bhan A, Gaynor BJ, Ryan K, Brody JA, Zhong X, Wei Q, Kammers K, Kanchan K, Iyer K, Kowalski MH, Pitsillides AN, Cupples LA, Li B, Schlaeger TM, Shuldiner AR, O'Connell JR, Ruczinski I, Mitchell BD, Faraday N, Taub MA, Becker LC, Lewis JP, Mathias RA, Johnson AD. Genome sequencing unveils a regulatory landscape of platelet reactivity. Nature communications. 12(1), 3626, 2021. [JCR]　[WOS]
Yang Meng-Ting, Chang Wei-Hung, Kuo Tien-Fen, Shen Ming-Yi, Yang Chu-Wen, Tien Yin-Jing, Lai Bun-Yueh, Chen Yet-Ran, Chang Yi-Cheng, Yang Wen-Chin. Identification of Novel Biomarkers for Pre-diabetic Diagnosis Using a Combinational Approach. Frontiers in Endocrinology. 12, 1-12, 2021. [JCR]　[WOS]
Li CC, Chang CC, Cherng YG, Lin CS, Yeh CC, Chang YC, Hu CJ, Shih CC, Chen TL, Liao CC. Risk and outcomes of diabetes in patients with epilepsy. Scientific reports. 11(1), 18888, 2021. [JCR]　[WOS]
Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch DP, Shetty AC, Blackwell TW, Smith AV, Wong Q, Liu X, Conomos MP, Bobo DM, Aguet F, Albert C, Alonso A, Ardlie KG, Arking DE, Aslibekyan S, Auer PL, Barnard J, Barr RG, Barwick L, Becker LC, Beer RL, Benjamin EJ, Bielak LF, Blangero J, Boehnke M, Bowden DW, Brody JA, Burchard EG, Cade BE, Casella JF, Chalazan B, Chasman DI, Chen YI, Cho MH, Choi SH, Chung MK, Clish CB, Correa A, Curran JE, Custer B, Darbar D, Daya M, de Andrade M, DeMeo DL, Dutcher SK, Ellinor PT, Emery LS, Eng C, Fatkin D, Fingerlin T, Forer L, Fornage M, Franceschini N, Fuchsberger C, Fullerton SM, Germer S, Gladwin MT, Gottlieb DJ, Guo X, Hall ME, He J, Heard-Costa NL, Heckbert SR, Irvin MR, Johnsen JM, Johnson AD, Kaplan R, Kardia SLR, Kelly T, Kelly S, Kenny EE, Kiel DP, Klemmer R, Konkle BA, Kooperberg C, Kottgen A, Lange LA, Lasky-Su J, Levy D, Lin X, Lin KH, Liu C, Loos RJF, Garman L, Gerszten R, Lubitz SA, Lunetta KL, Mak ACY, Manichaikul A, Manning AK, Mathias RA, McManus DD, McGarvey ST, Meigs JB, Meyers DA, Mikulla JL, Minear MA, Mitchell BD, Mohanty S, Montasser ME, Montgomery C, Morrison AC, Murabito JM, Natale A, Natarajan P, Nelson SC, North KE, O'Connell JR, Palmer ND, Pankratz N, Peloso GM, Peyser PA, Pleiness J, Post WS, Psaty BM, Rao DC, Redline S, Reiner AP, Roden D, Rotter JI, Ruczinski I, Sarnowski C, Schoenherr S, Schwartz DA, Seo JS, Seshadri S, Sheehan VA, Sheu WH, Shoemaker MB, Smith NL, Smith JA, Sotoodehnia N, Stilp AM, Tang W, Taylor KD, Telen M, Thornton TA, Tracy RP, Van Den Berg DJ, Vasan RS, Viaud-Martinez KA, Vrieze S, Weeks DE, Weir BS, Weiss ST, Weng LC, Willer CJ, Zhang Y, Zhao X, Arnett DK, Ashley-Koch AE, Barnes KC, Boerwinkle E, Gabriel S, Gibbs R, Rice KM, Rich SS, Silverman EK, Qasba P, Gan W, Papanicolaou GJ, Nickerson DA, Browning SR, Zody MC, Zollner S, Wilson JG, Cupples LA, Laurie CC, Jaquish CE, Hernandez RD, O'Connor TD, Abecasis GR. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 590(7845), 290-299, 2021. [JCR]　[WOS]
Chang YC, Hee SW, Chuang LM. T helper 17 cells: A new actor on the stage of type 2 diabetes and aging?. Journal of diabetes investigation. 12(6), 909-913, 2021. [JCR]　[WOS]
Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Magi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, Marz W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayan J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparso T, Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ, Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Bluher M, Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Franberg M, Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA, Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jorgensen ME, Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I, Kuulasmaa T, Kuusisto J, Lall K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H, Lin SY, Lindstrom J, Linneberg A, Liu J, Lorenzo C, Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN, Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA, Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I, Sabanayagam C, Sandow K, Sattar N, Schurmann A, Shi J, Stringham HM, Taylor KD, Teslovich TM, Thuesen B, Timmers PRHJ, Tremoli E, Tsai MY, Uitterlinden A, van Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV, Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis GR, Adair LS, Aguilar-Salinas CA, Alarcon-Riquelme ME, An P, Aviles-Santa L, Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E, Bohm BO, Bonnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A, Cucca F, de Silva HJ, Dedoussis G, Elmstahl S, Evans MK, Ferrannini E, Ferrucci L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X, Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E, James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR, Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS, Korner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ, Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE, Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njolstad I, O'Connell JR, Oldehinkel AJ, Ong KK, Padmanabhan S, Palmer CNA, Palmer ND, Pedersen O, Pennell CE, Porteous DJ, Pramstaller PP, Province MA, Psaty BM, Qi L, Raffel LJ, Rauramaa R, Redline S, Ridker PM, Rosendaal FR, Saaristo TE, Sandhu M, Saramies J, Schneiderman N, Schwarz P, Scott LJ, Selvin E, Sever P, Shu XO, Slagboom PE, Small KS, Smith BH, Snieder H, Sofer T, Sorensen TIA, Spector TD, Stanton A, Steves CJ, Stumvoll M, Sun L, Tabara Y, Tai ES, Timpson NJ, Tonjes A, Tuomilehto J, Tusie T, Uusitupa M, van der Harst P, van Duijn C, Vitart V, Vollenweider P, Vrijkotte TGM, Wagenknecht LE, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Wei WB, Wickremasinghe AR, Willemsen G, Wilson JF, Wong TY, Wu JY, Xiang AH, Yanek LR, Yengo L, Yokota M, Zeggini E, Zheng W, Zonderman AB, Rotter JI, Gloyn AL, McCarthy MI, Dupuis J, Meigs JB, Scott RA, Prokopenko I, Leong A, Liu CT, Parker SCJ, Mohlke KL, Langenberg C, Wheeler E, Morris AP, Barroso I. The trans-ancestral genomic architecture of glycemic traits. Nature genetics. 53(6), 840-860, 2021. [JCR]　[WOS]
Chuang Gwo-Tsann, Liu Pi-Hua, Chyan Tsui-Wei, Huang Chen-Hao, Huang Yu-Yao, Lin Chia-Hung, Lin Jou-Wei, Hsu Chih-Neng, Tsai Ru-Yi, Hsieh Meng-Lun, Lee Hsiao-Lin, Yang Wei-shun, Robinson-Cohen Cassianne, Hsiung Chia-Ni, Shen Chen-Yang, Chang Yi-Cheng. Genome-wide association study for circulating fibroblast growth factor 21 and 23. Scientific Reports. 10(1), 2020-09. [JCR]　[WOS]
Chang Yi-Cheng, Chao Seh-Huang, Chen Ching-Chu, Ser Kong-Han, Chong Keong, Lu Chieh-Hsiang, Hsieh Meng-Lun, Huang Yu-Yao, Lee Yi-Chih, Hsu Chih-Cheng, Chuang Lee-Ming, Lee Wei-Jei. The Effects of Bariatric Surgery on Renal, Neurological, and Ophthalmic Complications in Patients with Type 2 Diabetes: the Taiwan Diabesity Study. Obesity Surgery. 1-10, 2020-07. [JCR]　[WOS]
Yang Wei-Shun, Chang Yi-Cheng, Hsieh Meng-Lun, Wang Jiun-Ling, Wu Li-Chiu, Chang Chia-Hsuin. Stratified risks of infection-related hospitalization in patients with chronic kidney disease - A prospective cohort study. Scientific Reports. 10(1), 2020-03. [JCR]　[WOS]
Hsiung Chia-Ni, Chang Yi-Cheng, Lin Chien-Wei, Chang Chia-Wei, Chou Wen-Cheng, Chu Hou-Wei, Su Ming-Wei, Wu Pei-Ei, Shen Chen-Yang. The Causal Relationship of Circulating Triglyceride and Glycated Hemoglobin: A Mendelian Randomization Study. The Journal of Clinical Endocrinology & Metabolism. 105(3),908-919, 2020-03. [JCR]　[WOS]
Li Xihao, , Li Zilin, Zhou Hufeng, Gaynor Sheila M., Liu Yaowu, Chen Han, Sun Ryan, Dey Rounak, Arnett Donna K., Aslibekyan Stella, Ballantyne Christie M., Bielak Lawrence F., Blangero John, Boerwinkle Eric, Bowden Donald W., Broome Jai G., Conomos Matthew P., Correa Adolfo, Cupples L. Adrienne, Curran Joanne E., Freedman Barry I., Guo Xiuqing, Hindy George, Irvin Marguerite R., Kardia Sharon L. R., Kathiresan Sekar, Khan Alyna T., Kooperberg Charles L., Laurie Cathy C., Liu X. Shirley, Mahaney Michael C., Manichaikul Ani W., Martin Lisa W., Mathias Rasika A., McGarvey Stephen T., Mitchell Braxton D., Montasser May E., Moore Jill E., Morrison Alanna C., O’Connell Jeffrey R., Palmer Nicholette D., Pampana Akhil, Peralta Juan M., Peyser Patricia A., Psaty Bruce M., Redline Susan, Rice Kenneth M., Rich Stephen S., Smith Jennifer A., Tiwari Hemant K., Tsai Michael Y., Vasan Ramachandran S., Wang Fei Fei, Weeks Daniel E., Weng Zhiping, Wilson James G., Yanek Lisa R., Neale Benjamin M., Sunyaev Shamil R., Abecasis Gonçalo R., Rotter Jerome I., Willer Cristen J., Peloso Gina M., Natarajan Pradeep, Lin Xihong, . Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nature Genetics. 52(9), 969-983, 2020. [JCR]　[WOS]
Chen Ta-Liang, Lin Chao-Shun, Lin Jui-An, Yeh Chun-Chieh, Sung Li-Chin, Chang Yi-Cheng, Shih Chun-Chuan, Liao Chien-Chang. Evaluating Risk of Incident Diabetes Between Patients Who Used Lovastatin and Red Yeast Rice Prescriptions (LipoCol Forte): A Retrospective Cohort Study Based on a Real-World Database. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 13,89-98, 2020. [JCR]　[WOS]
Bick Alexander G., , Weinstock Joshua S., Nandakumar Satish K., Fulco Charles P., Bao Erik L., Zekavat Seyedeh M., Szeto Mindy D., Liao Xiaotian, Leventhal Matthew J., Nasser Joseph, Chang Kyle, Laurie Cecelia, Burugula Bala Bharathi, Gibson Christopher J., Lin Amy E., Taub Margaret A., Aguet Francois, Ardlie Kristin, Mitchell Braxton D., Barnes Kathleen C., Moscati Arden, Fornage Myriam, Redline Susan, Psaty Bruce M., Silverman Edwin K., Weiss Scott T., Palmer Nicholette D., Vasan Ramachandran S., Burchard Esteban G., Kardia Sharon L. R., He Jiang, Kaplan Robert C., Smith Nicholas L., Arnett Donna K., Schwartz David A., Correa Adolfo, de Andrade Mariza, Guo Xiuqing, Konkle Barbara A., Custer Brian, Peralta Juan M., Gui Hongsheng, Meyers Deborah A., McGarvey Stephen T., Chen Ida Yii-Der, Shoemaker M. Benjamin, Peyser Patricia A., Broome Jai G., Gogarten Stephanie M., Wang Fei Fei, Wong Quenna, Montasser May E., Daya Michelle, Kenny Eimear E., North Kari E., Launer Lenore J., Cade Brian E., Bis Joshua C., Cho Michael H., Lasky-Su Jessica, Bowden Donald W., Cupples L. Adrienne, Mak Angel C. Y., Becker Lewis C., Smith Jennifer A., Kelly Tanika N., Aslibekyan Stella, Heckbert Susan R., Tiwari Hemant K., Yang Ivana V., Heit John A., Lubitz Steven A., Johnsen Jill M., Curran Joanne E., Wenzel Sally E., Weeks Daniel E., Rao Dabeeru C., Darbar Dawood, Moon Jee-Young, Tracy Russell P., Buth Erin J., Rafaels Nicholas, Loos Ruth J. F., Durda Peter, Liu Yongmei, Hou Lifang, Lee Jiwon, Kachroo Priyadarshini, Freedman Barry I., Levy Daniel, Bielak Lawrence F., Hixson James E., Floyd James S., Whitsel Eric A., Ellinor Patrick T., Irvin Marguerite R., Fingerlin Tasha E., Raffield Laura M., Armasu Sebastian M., Wheeler Marsha M., Sabino Ester C., Blangero John, Williams L. Keoki, Levy Bruce D., Sheu Wayne Huey-Herng, Roden Dan M., Boerwinkle Eric, Manson JoAnn E., Mathias Rasika A., Desai Pinkal, Taylor Kent D., Johnson Andrew D., Auer Paul L., Kooperberg Charles, Laurie Cathy C., Blackwell Thomas W., Smith Albert V., Zhao Hongyu, Lange Ethan, Lange Leslie, Rich Stephen S., Rotter Jerome I., Wilson James G., Scheet Paul, Kitzman Jacob O., Lander Eric S., Engreitz Jesse M., Ebert Benjamin L., Reiner Alexander P., Jaiswal Siddhartha, Abecasis Gonçalo, Sankaran Vijay G., Kathiresan Sekar, Natarajan Pradeep. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 586(7831), 763-768, 2020. [JCR]　[WOS]
Lin Chao-Shun, Chang Chuen-Chau, Yeh Chun-Chieh, Chang Yi-Cheng, Chen Ta-Liang, Liao Chien-Chang. Outcomes after surgery in patients with diabetes who used metformin: a retrospective cohort study based on a real-world database. BMJ Open Diabetes Research & Care. 8(2), e001351, 2020. [JCR]　[WOS]
Yang Wei-Shun, Chang Yi-Cheng, Chang Chia-Hsuin, Wu Li-Chiu, Wang Jiun-Ling, Lin Hsien-Ho. The Association Between Body Mass Index and the Risk of Hospitalization and Mortality due to Infection: A Prospective Cohort Study. Open Forum Infectious Diseases. 8(1), ofaa545, 2020. [JCR]　[WOS]
Lee CC, Shih YC, Kang ML, Chang YC, Chuang LM, Devaraj R, Juan LJ. Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-alpha-acetylation of Pgc1alpha. Molecular cell. 76(3),500-, 2019-11. [JCR]　[WOS]
Shih Shyang-Rong, Liao Shu-Lang, Shih Chih-Wei, Wei Yi-Hsuan, Lu Ting-Xuan, Chou Chien-Hsiang, Yen Er-Yen, Chang Yi-Cheng, Lin Chia-Chi, Chi Yu-Chiao, Yang Wei-Shiung, Tsai Feng-Chiao. Fibroblast Growth Factor Receptor Inhibitors Reduce Adipogenesis of Orbital Fibroblasts and Enhance Myofibroblastic Differentiation in Graves’ Orbitopathy. Ocular Immunology and Inflammation. 1-10, 2019-10. [JCR]　[WOS]
Chang YC, Hua SC, Chang CH, Kao WY, Lee HL, Chuang LM, Huang YT, Lai MS. High TSH Level within Normal Range Is Associated with Obesity, Dyslipidemia, Hypertension, Inflammation, Hypercoagulability, and the Metabolic Syndrome: A Novel Cardiometabolic Marker. Journal of clinical medicine. 8(6), 2019-06. [JCR]　[WOS]
Diabetes Association of the Republic of China (Taiwan). Executive summary of the DAROC clinical practice guidelines for diabetes care- 2018. Journal of the Formosan Medical Association. 119, 577-586, 2019-04-03. [JCR]　[WOS]
Lin CS, Chang CC, Lee YW, Liu CC, Yeh CC, Chang YC, Chuang MT, Chang TH, Chen TL, Liao CC. Adverse Outcomes after Major Surgeries in Patients with Diabetes: A Multicenter Matched Study. Journal of clinical medicine. 8(1), 2019-01. [JCR]　[WOS]
Chang YC, Chang CH, Huang YT, Yeh YC, Yang WS. Tu Yk,. Sleep Duration and Proteinuria Progression: A Population-Based Cohort Study. AMERICAN JOURNAL OF NEPHROLOGY. 49, 41–51, 2019-01. [JCR]　[WOS]
Yu CW, Cheng KC, C LC, Lin MX, Chang YC, Hwang-Verslues WW. Pro-inflammatory cytokines IL-6 and CCL2 suppress circadian gene Period2 expression in mammary epithelial cells. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS. 1861(11), 1007-1017, 2018-11. [JCR]　[WOS]
Wang WC, Chiu YF, Chung RH, Hwu CM, Lee IT, Lee CH, Chang YC, Hung KY, Quertermous T, Chen YDI, Hsiung CA. IGF1 Gene Is Associated With Triglyceride Levels In Subjects With Family History Of Hypertension From The SAPPHIRe And TWB Projects. INTERNATIONAL JOURNAL OF MEDICAL SCIENCES. 15(10), 1035-1042, 2018-06. [JCR]　[WOS]
Lin HH, Wu CY, Wang CH, Fu H, Lonnroth K, Chang YC, Huang YT. Association of Obesity, Diabetes, and Risk of Tuberculosis: Two Population-Based Cohorts. CLINICAL INFECTIOUS DISEASES. 66(5), 699-705, 2018-02. [JCR]　[WOS]
Chang YC, Hee SW, Lee WJ, Li HY, Chang TJ, Lin MW, Hung YJ, Lee IT, Hung KY, Assimes T, Knowles JW, Nong JY, Lee PC, Chiu YF, Chuang LM. Genome-wide scan for circulating vascular adhesion protein-1 levels: MACROD2 as a potential transcriptional regulator of adipogenesis. Journal of diabetes investigation. 9(5), 1067-1074, 2018. [JCR]　[WOS]
Chalkia D, Chang YC, Derbeneva O, Lvova M, Wang P, Mishmar D, Liu X, Singh LN, Chuang LM, Wallace DC. Mitochondrial DNA associations with East Asian metabolic syndrome. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 1859(9), 878-892, 2018. [JCR]　[WOS]
Yu Chan-Wei, Cheng Kuo-Chih, Chen Ling-Chih, Lin Meng-Xuan, Chang Yi-Cheng, Hwang-Verslues Wendy W. Pro-inflammatory cytokines IL-6 and CCL2 suppress expression of circadian gene Period2 in mammary epithelial cells. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1861(11), 1007-1017, 2018. [JCR]　[WOS]
Chang YC, Chang CH, Huang YT, Yeh YC, Yang WS. Tu Yk. Sleep and progression of proteinuria: a large population-based cohort study. AMERICAN JOURNAL OF NEPHROLOGY. 49(1), 41-51, 2018. [JCR]　[WOS]
Lee WJ, Chang YC, Almalki O, Chao SH, Lu CH, Chen CC, Huang YY, Lee YC, Hsu CC. Study design and recruitment for a prospective controlled study of diabesity: Taiwan Diabesity Study. Asian journal of surgery. 42(1), 244-250, 2018. [JCR]　[WOS]
Chang YC, Chang CH, Yeh YC, Chuang LM, Tu YK. Subclinical and overt hypothyroidism is associated with reduced glomerular filtration rate and proteinuria: a large cross-sectional population study. Scientific reports. 8(1), 2031, 2018. [JCR]　[WOS]
Chu LM, Liu CC, Yeh CC, Chang YC, Hu CJ, Shih CC, Cherng YG, Chen TL, Liao CC. Increased diabetes risk and interaction with social and medical events in patients upon stroke: Two nationwide studies. ATHEROSCLEROSIS. 265, 87-92, 2017-10. [JCR]　[WOS]
Lin SC; Chih-Chung Liu CC; Chun-Chieh Yeh CC; Chang YC; Chi-Li Chung; Lane HL; Shih CC; Chen TL; Liao CC. Diabetes Risks and Outcomes in Chronic Obstructive Pulmonary Disease Patients: Two Nationwide Population-Based Retrospective Cohort Studies. Plos One. 12(8), e0181815, 2017-08. [JCR]　[WOS]
Lin CH, Chang YC, Chuang LM. Early detection of diabetic kidney disease: present limitations and future perspectives. World journal of diabetes. 7(14), 290-301, 2017-07. [JCR]　[WOS]
Chang CH, Lin JW, Chen ST, Lai MS, Chuang LM, Chang YC. Dipeptidyl Peptidase-4 Inhibitor Use Is Not Associated With Acute Pancreatitis in High-Risk Type 2 Diabetic Patients: A Nationwide Cohort Study. Medicine. 95(7), e2603, 2016. [JCR]　[WOS]
Chang TJ, Wang WC, Hsiung CA, He CT, Lin MW, Sheu WH, Chang YC, Quertermous T, Chen I, Rotter J, Chuang LM. Genetic Variation in the Human SORBS1 Gene is Associated With Blood Pressure Regulation and Age at Onset of Hypertension: A SAPPHIRe Cohort Study. Medicine. 95(10), e2970, 2016. [JCR]　[WOS]
Chang TJ, Tseng HC, Liu MW, Chang YC, Hsieh ML, Chuang LM. Glucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation. Scientific reports. 6, 23403, 2016. [JCR]　[WOS]
Chang EY, Chang YC, Shun CT, Tien YW, Tsai SH, Hee SW, Chen IJ, Chuang LM. Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2. PloS one. 11(1), e0147390, 2016. [JCR]　[WOS]
Chang CH, Chang YC, Lin JW, Caffrey JL, Wu LC, Lai MS, Chuang LM. No increased risk of hospitalization for heart failure for patients treated with dipeptidyl peptidase-4 inhibitors in Taiwan. International journal of cardiology. 220, 14-20, 2016. [JCR]　[WOS]
Chang CH, Chang YC, Lin JW, Chuang LM. Reply to 'Long-term use of acarbose and CV event: confusing finding from mega data bank'. Diabetic medicine : a journal of the British Diabetic Association. epub, 2016. [JCR]　[WOS]
Weng TC, Chang CH, Dong YH, Chang YC, Chuang LM. Anaemia and related nutrient deficiencies after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis. BMJ open. 5(7), e006964, 2015. [JCR]　[WOS]
Chang CH, Chang YC, Lin JW, Chen ST, Chuang LM, Lai MS. Cardiovascular risk associated with acarbose versus metformin as the first-line treatment in patients with type 2 diabetes: a nationwide cohort study. The Journal of clinical endocrinology and metabolism. 100(3), 1121-9, 2015. [JCR]　[WOS]
Chang YC, Chuang LM, Lin JW, Chen ST, Lai MS, Chang CH. Cardiovascular risks associated with second-line oral antidiabetic agents added to metformin in patients with Type 2 diabetes: a nationwide cohort study. Diabetic medicine : a journal of the British Diabetic Association. 32(11), 1460-9, 2015. [JCR]　[WOS]
Chang YC, Wu CC, Lin CH, Wu YW, Yang YC, Chang TJ, Jiang YD, Chuang LM. Early Myocardial Repolarization Heterogeneity Is Detected by Magnetocardiography in Diabetic Patients with Cardiovascular Risk Factors. PloS one. 10(7), e0133192, 2015. [JCR]　[WOS]
Chang TJ, Chiu YF, Sheu WH, Shih KC, Hwu CM, Quertermous T, Jou YS, Kuo SS, Chang YC, Chuang LM. Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population. Scientific reports. 5, 14380, 2015. [JCR]　[WOS]
Liao CC, Shih CC, Yeh CC, Chang YC, Hu CJ, Lin JG, Chen TL. Impact of Diabetes on Stroke Risk and Outcomes: Two Nationwide Retrospective Cohort Studies. Medicine. 94(52), e2282, 2015. [JCR]　[WOS]
Chang YC, Chang EY, Chuang LM. Recent progress in the genetics of diabetic microvascular complications. World journal of diabetes. 6(5), 715-25, 2015. [JCR]　[WOS]
Chang CH, Chang YC, Lee YC, Liu YC, Chuang LM, Lin JW. Severe hepatic injury associated with different statins in patients with chronic liver disease: a nationwide population-based cohort study. Journal of gastroenterology and hepatology. 30(1), 155-62, 2015. [JCR]　[WOS]
Chang YC, Hee SW, Hsieh ML, Jeng YM, Chuang LM. The Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for Treatment. Analytical cellular pathology (Amsterdam). 2015, 972891, 2015.　[WOS]
Wu Y, Gao H, Li H, Tabara Y, Nakatochi M, Chiu YF, Park EJ, Wen W, Adair LS, Borja JB, Cai Q, Chang YC, Chen P, Croteau-Chonka DC, Fogarty MP, Gan W, He CT, Hsiung CA, Hwu CM, Ichihara S, Igase M, Jo J, Kato N, Kawamoto R, Kuzawa CW, Lee JJ, Liu J, Lu L, McDade TW, Osawa H, Sheu WH, Teo Y, Vadlamudi S, Van Dam RM, Wang Y, Xiang YB, Yamamoto K, Ye X, Young TL, Zheng W, Zhu J, Shu XO, Shin C, Jee SH, Chuang LM, Miki T, Yokota M, Lin X, Mohlke KL, Tai ES. A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Human molecular genetics. 23(4), 1108-19, 2014. [JCR]
Huang CK, Yang CY, Jeng YM, Chen CL, Wu HH, Chang YC, Ma C, Kuo WH, Chang KJ, Shew JY, Lee WH. Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-kappaB-mediated antiapoptotic pathway. Oncogene. 33(23), 2968-77, 2014. [JCR]
Chang CH, Chang YC, Wu LC, Lin JW, Chuang LM, Lai MS. Different angiotensin receptor blockers and incidence of diabetes: a nationwide population-based cohort study. Cardiovascular diabetology. 13, 91, 2014. [JCR]　[WOS]
Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abecasis GR, Adair LS, Almgren P, Atalay M, Aung T, Baldassarre D, Balkau B, Bao Y, Barnett AH, Barroso I, Basit A, Been LF, Beilby J, Bell GI, Benediktsson R, Bergman RN, Boehm BO, Boerwinkle E, Bonnycastle LL, Burtt N, Cai Q, Campbell H, Carey J, Cauchi S, Caulfield M, Chan JC, Chang LC, Chang TJ, Chang YC, Charpentier G, Chen CH, Chen H, Chen YT, Chia KS, Chidambaram M, Chines PS, Cho NH, Cho YM, Chuang LM, Collins FS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Danesh J, Das D, de Faire U, Dedoussis G, Deloukas P, Dimas AS, Dina C, Doney AS, Donnelly PJ, Dorkhan M, van Duijn C, Dupuis J, Edkins S, Elliott P, Emilsson V, Erbel R, Eriksson JG, Escobedo J, Esko T, Eury E, Florez JC, Fontanillas P, Forouhi NG, Forsen T, Fox C, Fraser RM, Frayling TM, Froguel P, Frossard P, Gao Y, Gertow K, Gieger C, Gigante B, Grallert H, Grant GB, Grrop LC, Groves CJ, Grundberg E, Guiducci C, Hamsten A, Han BG, Hara K, Hassanali N, Hattersley AT, Hayward C, Hedman AK, Herder C, Hofman A, Holmen OL, Hovingh K, Hreidarsson AB, Hu C, Hu FB, Hui J, Humphries SE, Hunt SE, Hunter DJ, Hveem K, Hydrie ZI, Ikegami H, Illig T, Ingelsson E, Islam M, Isomaa B, Jackson AU, Jafar T, James A, Jia W, Jockel KH, Jonsson A, Jowett JB, Kadowaki T, Kang HM, Kanoni S, Kao WH, Kathiresan S, Kato N, Katulanda P, Keinanen-Kiukaanniemi KM, Kelly AM, Khan H, Khaw KT, Khor CC, Kim HL, Kim S, Kim YJ, Kinnunen L, Klopp N, Kong A, Korpi-Hyovalti E, Kowlessur S, Kraft P, Kravic J, Kristensen MM, Krithika S, Kumar A, Kumate J, Kuusisto J, Kwak SH, Laakso M, Lagou V, Lakka TA, Langenberg C, Langford C, Lawrence R, Leander K, Lee JM, Lee NR, Li M, Li X, Li Y, Liang J, Liju S, Lim WY, Lind L, Lindgren CM, Lindholm E, Liu CT, Liu JJ, Lobbens S, Long J, Loos RJ, Lu W, Luan J, Lyssenko V, Ma RC, Maeda S, Magi R, Mannisto S, Matthews DR, Meigs JB, Melander O, Metspalu A, Meyer J, Mirza G, Mihailov E, Moebus S, Mohan V, Mohlke KL, Morris AD, Muhleisen TW, Muller-Nurasyid M, Musk B, Nakamura J, Nakashima E, Navarro P, Ng PK, Nica AC, Nilsson PM, Njolstad I, Nothen MM, Ohnaka K, Ong TH, Owen KR, Palmer CN, Pankow JS, Park KS, Parkin M, Pechlivanis S, Pedersen NL, Peltonen L, Perry JR, Peters A, Pinidiyapathirage JM, Platou CG, Potter S, Price JF, Qi L, Radha V, Rallidis L, Rasheed A, Rathman W, Rauramaa R, Raychaudhuri S, Rayner NW, Rees SD, Rehnberg E, Ripatti S, Robertson N, Roden M, Rossin EJ, Rudan I, Rybin D, Saaristo TE, Salomaa V, Saltevo J, Samuel M, Sanghera DK, Saramies J, Scott J, Scott LJ, Scott RA, Segre AV, Sehmi J, Sennblad B, Shah N, Shah S, Shera AS, Shu XO, Shuldiner AR, Sigurdsson G, Sijbrands E, Silveira A, Sim X, Sivapalaratnam S, Small KS, So WY, Stancakova A, Stefansson K, Steinbach G, Steinthorsdottir V, Stirrups K, Strawbridge RJ, Stringham HM, Sun Q, Suo C, Syvanen AC, Takayanagi R, Takeuchi F, Tay WT, Teslovich TM, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Trakalo J, Tremoli E, Trip MD, Tsai FJ, Tuomi T, Tuomilehto J, Uitterlinden AG, Valladares-Salgado A, Vedantam S, Veglia F, Voight BF, Wang C, Wareham NJ, Wennauer R, Wickremasinghe AR, Wilsgaard T, Wilson JF, Wiltshire S, Winckler W, Wong TY, Wood AR, Wu JY, Wu Y, Yamamoto K, Yamauchi T, Yang M, Yengo L, Yokota M, Young R, Zabaneh D, Zhang F, Zhang R, Zheng W, Zimmet PZ, Altshuler D, Bowden DW, Cho YS, Cox NJ, Cruz M, Hanis CL, Kooner J, Lee JY, Seielstad M, Teo YY, Boehnke M, Parra EJ, Chambers JC, Tai ES, McCarthy MI, Morris AP. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature genetics. 46(3), 234-44, 2014. [JCR]
Liao CC, Lin CS, Shih CC, Yeh CC, Chang YC, Lee YW, Chen TL. Increased risk of fracture and postfracture adverse events in patients with diabetes: two nationwide population-based retrospective cohort studies. Diabetes care. 37(8), 2246-52, 2014. [JCR]
Chang YC, Liu PH, Yu YH, Kuo SS, Chang TJ, Jiang YD, Nong JY, Hwang JJ, Chuang LM. Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis. PloS one. 9(4), e95045, 2014. [JCR]
Yeh CC, Liao CC, Chang YC, Jeng LB, Yang HR, Shih CC, Chen TL. Adverse outcomes after noncardiac surgery in patients with diabetes: a nationwide population-based retrospective cohort study. Diabetes care. 36(10), 3216-21, 2013. [JCR]
Wu VC, Wu CK, Chang YC, Young GH, Chen SC, Yang WS, Chen CY, Wang WJ, Lin CY, Lin YH, Lin SL, Chueh SC, Wu KD. Association of the variations in the HSD3beta gene with primary aldosteronism. Journal of hypertension. 31(7), 1396-405; discussion 1405, 2013. [JCR]
Chang YC, Yu YH, Shew JY, Lee WJ, Hwang JJ, Chen YH, Chen YR, Wei PC, Chuang LM, Lee WH. Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human. EMBO molecular medicine. 5(8), 1165-79, 2013. [JCR]
Chang YC, Chiu YF, Liu PH, Hee SW, Chang TJ, Jiang YD, Lee WJ, Lee PC, Kao HY, Hwang JJ, Chuang LM. Genetic variation in the NOC gene is associated with body mass index in Chinese subjects. PloS one. 8(7), e69622, 2013. [JCR]
Tsai SH, Chang EY, Chang YC, Hee SW, Tsai YC, Chang TJ, Chuang LM. Knockdown of RyR3 enhances adiponectin expression through an atf3-dependent pathway. Endocrinology. 154(3), 1117-29, 2013. [JCR]
Hwang-Verslues WW, Chang PH, Jeng YM, Kuo WH, Chiang PH, Chang YC, Hsieh TH, Su FY, Lin LC, Abbondante S, Yang CY, Hsu HM, Yu JC, Chang KJ, Shew JY, Lee EY, Lee WH. Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy. Proceedings of the National Academy of Sciences of the United States of America. 110(30), 12331-6, 2013. [JCR]
Shih SR, Chang YC, Li HY, Liau JY, Lee CY, Chen CM, Chang TC. Preoperative prediction of papillary thyroid carcinoma prognosis with the assistance of computerized morphometry of cytology samples obtained by fine-needle aspiration: preliminary report. Head & neck. 35(1), 28-34, 2013.
Yu YH, Chang YC, Su TH, Nong JY, Li CC, Chuang LM. Prostaglandin reductase-3 negatively modulates adipogenesis through regulation of PPARgamma activity. Journal of lipid research. 54(9), 2391-9, 2013. [JCR]
Chang PH, Hwang-Verslues WW, Chang YC, Chen CC, Hsiao M, Jeng YM, Chang KJ, Lee EY, Shew JY, Lee WH. Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/beta-catenin pathway. Cancer research. 72(18), 4652-61, 2012. [JCR]
Li H, Kilpelainen TO, Liu C, Zhu J, Liu Y, Hu C, Yang Z, Zhang W, Bao W, Cha S, Wu Y, Yang T, Sekine A, Choi BY, Yajnik CS, Zhou D, Takeuchi F, Yamamoto K, Chan JC, Mani KR, Been LF, Imamura M, Nakashima E, Lee N, Fujisawa T, Karasawa S, Wen W, Joglekar CV, Lu W, Chang Y, Xiang Y, Gao Y, Liu S, Song Y, Kwak SH, Shin HD, Park KS, Fall CH, Kim JY, Sham PC, Lam KS, Zheng W, Shu X, Deng H, Ikegami H, Krishnaveni GV, Sanghera DK, Chuang L, Liu L, Hu R, Kim Y, Daimon M, Hotta K, Jia W, Kooner JS, Chambers JC, Chandak GR, Ma RC, Maeda S, Dorajoo R, Yokota M, Takayanagi R, Kato N, Lin X, Loos RJ. Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia. 55(4), 981-95, 2012. [JCR]
Chang YC, Chiu YF, Lee IT, Ho LT, Hung YJ, Hsiung CA, Quertermous T, Donlon T, Lee WJ, Lee PC, Chen CH, Mochly-Rosen D, Chuang LM. Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: gene-environmental interaction with alcohol consumption. BMC cardiovascular disorders. 12, 58, 2012. [JCR]
Chang YC, Liu PH, Tsai YC, Chiu YF, Shih SR, Ho LT, Lee WJ, Lu CH, Quertermous T, Curb JD, Lee WJ, Lee PC, He YH, Yeh JI, Hwang JJ, Tsai SH, Chuang LM. Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis. Journal of molecular medicine (Berlin, Germany). 90(7), 847-58, 2012.
Wei PC, Hsieh YH, Su MI, Jiang X, Hsu PH, Lo WT, Weng JY, Jeng YM, Wang JM, Chen PL, Chang YC, Lee KF, Tsai MD, Shew JY, Lee WH. Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease. Molecular cell. 48(5), 747-59, 2012. [JCR]
Cho YS, Chen CH, Hu C, Long J, Ong RT, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang YC, Kwak SH, Ma RC, Yamamoto K, Adair LS, Aung T, Cai Q, Chang LC, Chen YT, Gao Y, Hu FB, Kim HL, Kim S, Kim YJ, Lee JJ, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, Ng DP, Tay WT, Tsai FJ, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang TJ, Bao Y, Hedman AK, Morris AP, McCarthy MI, Takayanagi R, Park KS, Jia W, Chuang LM, Chan JC, Maeda S, Kadowaki T, Lee JY, Wu JY, Teo YY, Tai ES, Shu XO, Mohlke KL, Kato N, Han BG, Seielstad M. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nature genetics. 44(1), 67-72, 2012. [JCR]
Chang EY, Tsai SH, Shun CT, Hee SW, Chang YC, Tsai YC, Tsai JS, Chen HJ, Chou JW, Lin SY, Chuang LM. Prostaglandin reductase 2 modulates ROS-mediated cell death and tumor transformation of gastric cancer cells and is associated with higher mortality in gastric cancer patients. The American journal of pathology. 181(4), 1316-26, 2012. [JCR]
Chang YC, Chiu YF, Liu PH, Shih KC, Lin MW, Sheu WH, Quertermous T, Curb JD, Hsiung CA, Lee WJ, Lee PC, Chen YT, Chuang LM. Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort. Clinical endocrinology. 76(3), 365-72, 2012. [JCR]
Hee SW, Tsai SH, Chang YC, Chang CJ, Yu IS, Lee PC, Lee WJ, Yun-Chia Chang E, Chuang LM. The role of nocturnin in early adipogenesis and modulation of systemic insulin resistance in human. Obesity (Silver Spring, Md.). 20(8), 1558-65, 2012.
Chang TJ, Liu PH, Liang YC, Chang YC, Jiang YD, Li HY, Lo MT, Chen HS, Chuang LM. Genetic predisposition and nongenetic risk factors of thiazolidinedione-related edema in patients with type 2 diabetes. Pharmacogenetics and genomics. 21(12), 829-36, 2011. [JCR]
Wu CK, Chang YC, Hua SC, Wu HY, Lee WJ, Chiang FT, Hwang JJ, Lien WP, Chuang LM. A triglyceride-raising APOA5 genetic variant is negatively associated with obesity and BMI in the Chinese population. Obesity (Silver Spring, Md.). 18(10), 1964-8, 2010.
Chang YC, Lin JW, Wang LC, Chen HM, Hwang JJ, Chuang LM. Association of intraocular pressure with the metabolic syndrome and novel cardiometabolic risk factors. Eye (London, England). 24(6), 1037-43, 2010.
Chang YC, Chiu YF, Shih KC, Lin MW, Sheu WH, Donlon T, Curb JD, Jou YS, Chang TJ, Li HY, Chuang LM. Common PCSK1 haplotypes are associated with obesity in the Chinese population. Obesity (Silver Spring, Md.). 18(7), 1404-9, 2010.
Jiang YD, Chang YC, Chiu YF, Chang TJ, Li HY, Lin WH, Yuan HY, Chen YT, Chuang LM. SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes. BMC medical genetics. 11, 126, 2010. [JCR]　[WOS]
Chang YC, Chiu YF, Ho LL, Ting CT, Shih KC, Curb JD, Chen YD, Li HY, Chuang LM. TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance. Journal of molecular medicine (Berlin, Germany). 88(2), 183-92, 2010.
Chang YC, Chang LY, Chang TJ, Jiang YD, Lee KC, Kuo SS, Lee WJ, Chuang LM. The associations of LPIN1 gene expression in adipose tissue with metabolic phenotypes in the Chinese population. Obesity (Silver Spring, Md.). 18(1), 7-12, 2010.
Chang YC, Chang TJ, Lee WJ, Chuang LM. The relationship of visfatin/pre-B-cell colony-enhancing factor/nicotinamide phosphoribosyltransferase in adipose tissue with inflammation, insulin resistance, and plasma lipids. Metabolism: clinical and experimental. 59(1), 93-9, 2010. [JCR]
Chang YC, Chuang LM. The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication. American journal of translational research. 2(3), 316-31, 2010. [JCR]
Li HY, Chang YC, Wei JN, Chuang LM. Validation of diabetes risk scores for predicting diabetes diagnosed by oral glucose tolerance test. Diabetes care. 33(2), e26, 2010. [JCR]
Lin JW, Chang YC, Li HY, Chien YF, Wu MY, Tsai RY, Hsieh YC, Chen YJ, Hwang JJ, Chuang LM. Cross-sectional validation of diabetes risk scores for predicting diabetes, metabolic syndrome, and chronic kidney disease in Taiwanese. Diabetes care. 32(12), 2294-6, 2009. [JCR]
Wu CK, Tsai CT, Chang YC, Luo JL, Wang YC, Hwang JJ, Lin JL, Tseng CD, Chiang FT. Genetic polymorphisms of the angiotensin II type 1 receptor gene and diastolic heart failure. Journal of hypertension. 27(3), 502-7, 2009. [JCR]
Liu PH, Chang YC, Jiang YD, Chen WJ, Chang TJ, Kuo SS, Lee KC, Hsiao PC, Chiu KC, Chuang LM. Genetic variants of TCF7L2 are associated with insulin resistance and related metabolic phenotypes in Taiwanese adolescents and Caucasian young adults. The Journal of clinical endocrinology and metabolism. 94(9), 3575-82, 2009. [JCR]
Chang YC, Jiang JY, Jiang YD, Chiang FT, Hwang JJ, Lien WP, Chuang LM. Interaction of ADIPOQ genetic polymorphism with blood pressure and plasma cholesterol level on the risk of coronary artery disease. Circulation journal : official journal of the Japanese Circulation Society. 73(10), 1934-8, 2009. [JCR]
Huang MN, Chang YC, Wu CH, Hsieh SC, Yu CL. The prognostic values of soft tissue sonography for adult cellulitis without pus or abscess formation. Internal medicine journal. 39(12), 841-4, 2009. [JCR]
Chang YC, Liu PH, Lee WJ, Chang TJ, Jiang YD, Li HY, Kuo SS, Lee KC, Chuang LM. Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population. Diabetes. 57(8), 2245-52, 2008. [JCR]
Chang YC, Chang TJ, Jiang YD, Kuo SS, Lee KC, Chiu KC, Chuang LM. Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes. 56(10), 2631-7, 2007. [JCR]
Ku CS, Khaw M, Chia KS. Comment on: Chang et al. (2007) Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population: Diabetes 56:2631-2637. Diabetes. 56(12), e22; author reply e23, 2007. [JCR]

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