Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 謝清河 Hsieh, Patrick C.H.

Journal 83

Chen CH, Cheng YC, Hsieh ML, Lin PJ, Wissel EF, Steward T, Chang MC, Coonen J, Hacker TA, Kamp TJ, Hsieh PC. Gut microbiota modulation in cardiac cell therapy with immunosuppression in a nonhuman primate ischemia/reperfusion model. NPJ Regen. Med.. , 2025.
Cheng YY, Gregorich Z, Prajnamitra RP, Lundy DJ, Ma TY, Huang YH, Lee YC, Rua SC, Lin JH, Lin PJ, Wen Kuo C, Chen P, Yan YT, Tian R, Kamp TJ, Hsieh PCH*. Metabolic Changes Associated With Cardiomyocyte Dedifferentiation Enable Adult Mammalian Cardiac Regeneration. Circulation. 146, 1950-1967, 2022-12. [JCR]　[WOS]
Chiu YT, Tsai MH, Chan DZ, Ko HW, Lu HE, Huang CF, Lin YJ, Chang SL, Lo LW, Huang CY, Hu YF, Hsieh PCH, Chen SA. Generation of IBMS-iPSC-015, -016, -017 human induced pluripotent stem cells (IBMSi013-A, IBMSi014-A, and IBMSi015-A) derived from patients with atrial fibrillation. Stem Cell Research. , 2021-06. [JCR]　[WOS]
Raval AN, Schmuck EG, Roy S, Saito Y, Zhou T, Conklin J, Hacker TA, Koonce C, Boyer M, Stack K, Hebron E, Nagle SK, Hsieh PCH, Kamp TJ. Human iPSC-derived Committed Cardiac Progenitors Generate Cardiac Tissue Grafts in a Swine Ischemic Cardiomyopathy Model without Triggering Ventricular Arrhythmias. bioRxiv : the preprint server for biology. 02.14, 580375-580375, 2024-02.
Chen HC, Liu YW, Chang KC, Wu YW, Chen YM, Chao YK, Yu MY, Lundy DJ, CJ, Hsieh ML, Cheng YC, Prajnamitra RP, Lin PJ, Ruan SC, Chen DHK, Shih ESC, Chen KW, Chang SS, Chang CMC, Puntney R, Moy AW, Lee JJ, Wu DC, Hwang MJ, Coonen J, Hacker TA, Yen CLE, Rey FE, Kamp TJ, Hsieh PC*. Gut butyrate-producers confer post-infarction cardiac protection. Nature Communications. 14(1), 7249, 2023-11-09. [JCR]　[WOS]
Cheng YC, Hsieh ML, Lin CJ, Chang CMC, Huang CY, Puntney R, Moy AW, Ting CY, Chan DZH, Nicholson MW, Lin PJ, Chen CH, Kim GC, Zhang J, Coonen J, Basu P, Simmons HA, Liu YW, Hacker TA, Kamp TJ, Hsieh PCH*. Combined Treatment of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes and Endothelial Cells Regenerate the Infarcted Heart in Mice and Non-Human Primates. Circulation. 148(18), 1395-1409, 2023-10-31. [JCR]　[WOS]
Chiu CH, Hsuan CF, Lin SH, Hung YJ, Hwu CM, Hee SW, Lin SW, Fong SW, Hsieh PC, Yang WS, Lin WC, Lee HL, Hsieh ML, Li WY, Lin JW, Hsu CN, Wu VC, Chuang GT, Chang YC, Chuang LM. ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking. Journal of Biomedical Science. 30(1), 13-13, 2023-02. [JCR]
Lin CJ, Cheng YC, Chen HC, Chao YK, Nicholson MW, Yen ECL, Kamp TJ, Hsieh PC*. Commensal gut microbiota-derived acetate and propionate enhance heart adaptation in response to cardiac pressure overload in mice. Theranostics. 12(17), 7319-7334, 2022-10. [JCR]　[WOS]
Prajnamitra RP, YY, Beh CY, Lu CY, Lin JH, Ruan SC, Chen SL, Chen HC, Yang RB, Hsieh PC*. Depletion of gut microbiota improves the therapeutic efficacy of cancer nanomedicine. Theranostics. 12(17), 7390-7403, 2022-10. [JCR]　[WOS]
Chen SL, Lundy DJ, Ruan SC, Chen HC, Chao YK, Cheng YY, Prajnamitra PR, Liao CC, Lin CY, Lai JJ, Hsieh, PC*. The gut microbiota regulates acute foreign body reaction and tissue repair after biomaterial implantation. Biomaterials. 289, 121807, 2022-10. [JCR]　[WOS]
Nicholson MW, Huang C-Y, Wang J-Y, Ting C-Y, Cheng Y-C, Chan DZH, Lee Y-C, Hsu C-C, Hsu Y-H, Chang CMC, Hsieh ML, Cheng Y-Y, Lin Y-L, Chen C-H, Wu Y-T, Hacker TA, Wu JC, Kamp TJ, Hsieh PCH*. Cardio- and Neurotoxicity of Selected Anti-COVID-19 Drugs. Pharmaceuticals.. 15(6), 765, 2022-06. [JCR]　[WOS]
Nicholson MW, Ting CY , Chan ZH, Cheng YC, LeeYC , Hsu CC, Huang YC, Hsieh PC*. Utility of iPSC-Derived Cells for Disease Modeling, Drug Development, and Cell Therapy. Cells. 11(11), 1853, 2022-06. [JCR]　[WOS]
Huang CY, Nicholson MW, Wang JY, Ting CY, Tsai MH, Cheng YC, Liu CL, Chan DZH, Lee YC, Hsu CC, Hsu YH, Yang CF, Chang CM, Ruan SC, Lin PJ, Lin JH, Chen LL, Hsieh ML, Cheng YY, Hsu WT, Chen CH, Hsu YH, Wu YT, Hacker TA, Wu JC, Kamp TJ, Hsieh PC*. Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons. Cell Reports. 39(1), 110643, 2022-04. [JCR]　[WOS]
Beh CY, Prajnamitra RP, Chen LL, Hsieh PC*. Advances in Biomimetic Nanoparticles for Targeted Cancer Therapy and Diagnosis. Molecules. 26(16), 5052, 2021-08. [JCR]　[WOS]
Lundy DJ*, Nguyễn H, Hsieh PC*. Emerging Nano-Carrier Strategies for Brain Tumor Drug Delivery and Considerations for Clinical Translation. Pharmaceutics. 13(8), 1193, 2021-08. [JCR]　[WOS]
Ting CY, Huang CY, Chen HC, Chiu YW, Hsieh PC, Lee JJ*. Generation of induced pluripotent stem cells from a Bardet-Biedl syndrome patient carrying a homologous BBS2 c.534 + 1G > T mutation. Stem Cell Research. 55, 102480, 2021-08. [JCR]　[WOS]
Chen JS, Wang HK, Hsu CY, Su YT, Chen JS, Liang CL, Hsieh PC, Wu CC, Kwan AL*. HDAC1 deregulation promotes neuronal loss and deficit of motor function in stroke pathogenesis. Scientific Reports. 11(1), 16354-16354, 2021-08. [JCR]　[WOS]
Tsai MH, Chiu YT, Chan DZ, Wen CH, Syu SH, Lu HE, Huang CF, Lin YJ, Chang SL, Lo LW, Huang CY, Hu YF, Hsieh PCH, Chen SA. Generation of IBMS-iPSC-021, -022, -023 human induced pluripotent stem cells (IBMSi016-A, IBMSi017-A, and IBMSi018-A) derived from patients with the ALDH2 rs671 polymorphism. Stem Cell Research. 7, 17, 2021-06. [JCR]　[WOS]
Huang SS, Lee KJ, Chen HC, Prajnamitra RP, Hsu CH, Jian CB, Yu XE, Chueh DY, Kuo CW, Chiang TC, Choong OK, Huang SC, Beh CY, Chen LL, Lai JJ, Chen P, Kamp TJ, Tien YW, Lee HM, Hsieh PC*. Immune cell shuttle for precise delivery of nanotherapeutics for heart disease and cancer. Science Advances. 7 (17), eabf2400, 1-12, 2021-04. [JCR]　[WOS]
Chen CY, Lee DS, Choong OK, Chang SK, Hsu T, Nicholson MW, Liu LW, Lin PJ, Ruan SC, Lin SW, Hu CY, Hsieh PCH*. Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy. Scientific Reports. 11(1), 2377, 2021-01. [JCR]　[WOS]
Huang CY; Li LH; Hsu WT; Cheng YC; Nicholson MW; Liu CL; Ting CY; Ko HW; Hsu SH; Wen CH; Yan Z; Huang HP; Su HL; Chiang PM; Shen CN; Chen HF; Yen BL; Lu HN; Hwang SM; Chiou SH; Ho HN; Wu JY; Kamp TJ; Wu JC; Hsieh PC. Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank. Journal of Biomedical Science. 27(1), 92, 2020-09. [JCR]　[WOS]
Liu CL, Huang CY, Chen HC, Lu HE, Hsieh PC. Lee JJ. Generation of a gene corrected human isogenic IBMS-iPSC-014-C from polycystic-kidney-disease induced pluripotent stem cell line using CRISPR/Cas9. Stem Cell Research. 45, 101784, 2020-05. [JCR]　[WOS]
Lin HY, TsaiLK, Cheng YC, Lu HE, Huang CY, Hsieh PC, Lin CH. Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-048-05) from a patient with ALS and parkinsonism having a hexanucleotide repeat expansion mutation in C9orf72 gene. Stem Cell Research. 44, 101734, 2020-04. [JCR]　[WOS]
Choong OK, Chen CY, Zhang J, Lin JH, Lin PJ, Ruan SC, Kamp TJ, Hsieh PC*. Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction. Theranostics. 9(22), 6550-6567, 2019-08. [JCR]　[WOS]
Chen CY, Choong OK, Liu LY, Cheng YC, Li SC, Yen CY, Wu MR, Chiang MH, Tsang TJ, Wu YW, Lin LC, Chen YL, Lin WC, Hacker TA, Kamp TJ, Hsieh PC*. MicroRNA let-7-TGFBR3 signalling regulates cardiomyocyte apoptosis after infarction. EBioMedicine. 46, 236-247, 2019-08. [JCR]　[WOS]
Lin HI, Cheng YC, Ko HW, Wen CH, Lu HE, Huang CY, Hsieh PC, Lin CH. Generation of induced pluripotent stem cells (IBMSi011-A) from a patient with Parkinson's disease carrying LRRK2 p.I1371V mutation. Stem Cell Research. 37, 101447, 2019-05. [JCR]　[WOS]
Cheng YC, Lin HI, Syu SH, Lu HE, Huang CY, Lin CH, Hsieh PC*. Reprogramming of a human induced pluripotent stem cell (iPSC) line (IBMSi012-A) from an early-onset Parkinson's disease patient harboring a homozygous p.D331Y mutation in the PLA2G6 gene. Stem Cell Research. 37, 101432, 2019-05. [JCR]　[WOS]
Lee JJ, Cheng SJ, Huang CY, Chen CY, Feng L, Hwang DY, Kamp TJ, Chen HC*, Hsieh PC*. Primary cardiac manifestation of autosomal dominant polycystic kidney disease revealed by patient induced pluripotent stem cell-derived cardiomyocytes. EBioMedicine. 40, 675-684, 2019-02. [JCR]　[WOS]
Lundy DJ, Lee KJ, Peng IC, Hsu CH, Lin JH, Chen KH, Tien YW, Hsieh PC*. Inducing a Transient Increase in Blood–Brain Barrier Permeability for Improved Liposomal Drug Therapy of Glioblastoma Multiforme. ACS Nano. 13(1) ,97-113, 2019-01. [JCR]　[WOS]
Tang TW, Chen HC, Chen CY, Yen CY, Lin CJ, Prajnamitra RP, Chen LL, Ruan SC, Lin JH, Lin PJ, Lu HH, Kuo CW, Chang CM, Hall AD, Vivas EI, Shui JW, Chen P, Hacker TA, Rey FE, Kamp TJ, Hsieh PC*. Loss of Gut Microbiota Alters Immune System Composition and Cripples Postinfarction Cardiac Repair. Circulation. 139(5) 647-659, 2019-01. [JCR]　[WOS]
Wu JM, Cheng YY, Tang TW, Shih C, Chen JH, Hsieh PC*. Prostaglandin E2Receptor 2 Modulates Macrophage Activity for Cardiac Repair. Journal of the American Heart Association. 7(19), e009216, 2018-09. [JCR]　[WOS]
Hsu WT, Huang CY, Yen CY, Cheng AL, Hsieh PC*. The HER2 inhibitor lapatinib potentiates doxorubicin-induced cardiotoxicity through iNOS signaling. Theranostics. 8(12), 3176-3188, 2018-05. [JCR]　[WOS]
Carlsson L, Clarke JC, Yen C, Gregoire F, Albery T, Billger M, Egnell AC, Gan LM, Jennbacken K, Johansson E, Linhardt G, Martinsson S, Sadiq MW, Witman N, Wang QD, Chen CH, Wang YP, Lin S, Ticho B, Hsieh PC, Chien KR, Fritsche-Danielson R. Biocompatible, Purified VEGF-A mRNA Improves Cardiac Function after Intracardiac Injection 1 Week Post-myocardial Infarction in Swine. Molecular Therapy - Methods & Clinical Development. 9, 330-346, 2018-04. [JCR]　[WOS]
Cheng YC, Huang CY, Ho MC, Hsu YH, Syu SH, Lu HE, Lin HI, Lin CH, Hsieh PC*. Generation of 2 induced pluripotent stem cell lines derived from patients with Parkinson's disease carrying LRRK2 G2385R variant. Stem Cell Research. 28, 1-5, 2018-04. [JCR]　[WOS]
Liu SP, Hsu YH, Huang CY, Ho MC, Cheng YC, Wen CH, Lu HE, Tsai CH, Shyu WC, Hsieh PC*. Generation of novel induced pluripotent stem cell (iPSC) line from a 16-year-old sialidosis patient with NEU-1 gene mutation. Stem Cell Research. 28, 39-43, 2018-04. [JCR]　[WOS]
Lu HE, Yang YP, Chen YT, Wu YR, Wang CL, Tsai FT, Hwang DK, Lin TC, Chen SJ, Wang AG, Hsieh PC, Chiou SH*. Generation of patient-specific induced pluripotent stem cells from Leber's hereditary optic neuropathy. Stem Cell Research. 28, 56-60, 2018-04. [JCR]　[WOS]
Hsieh PC*, Kamp TJ. To Be Young at Heart. Cell Stem Cell. 22(4) 475-476, 2018-04. [JCR]　[WOS]
Hsu YH, Wu YT, Huang CY, Ho MC, Cheng YC, Syu SH, Lu HE, Chen YC, Tsai CL, Lin HC, Wei YH, Hsu YC, Hsieh PC*. Generation of an induced pluripotent stem cell line from a 39-year-old female patient with severe-to-profound non-syndromic sensorineural hearing loss and a A1555G mutation in the mitochondrial MTRNR1 gene. Stem Cell Research. 25, 245-249, 2017-12. [JCR]　[WOS]
Ho MC, Huang CY, Lee JJ, Hsu SH, Cheng YC, Hsu YH, Hwang DY, Lu HE, Chen HC, Hsieh PC*. Generation of an induced pluripotent stem cell line, IBMS-iPSC-014-05, from a female autosomal dominant polycystic kidney disease patient carrying a common mutation of R803X in PKD2. Stem Cell Research. 25, 38-41, 2017-12. [JCR]　[WOS]
Lin CH, Cheng YC, Lin HI, Ho MC, Hsu YH, Wen CH, Ko HW, Lu HE, Huang CY, Hsieh PC*. Generation of induced pluripotent stem cells from a patient with Parkinson's disease carrying LRRK2 p.I2012T mutation. Stem Cell Research. 25, 123-127, 2017-12. [JCR]　[WOS]
Lee JJ, Ho MC, Huang CY, Wen CH, Cheng YC, Hsu YH, Hwang DY, Lu HE, Chen HC, Hsieh PC*. Induced pluripotent stem cells derived from an autosomal dominant polycystic kidney disease patient carrying a PKD1 Q533X mutation. Stem Cell Research. 25, 83-87, 2017-12. [JCR]　[WOS]
Huang CY, Ho MC, Lee JJ, Hwang DY, Ko HW, Cheng YC, Hsu YH, Lu HE, Chen HC, Hsieh PC*. Generation of induced pluripotent stem cells derived from an autosomal dominant polycystic kidney disease patient with a p.Ser1457fs mutation in PKD1. Stem Cell Research. 24, 139-143, 2017-10. [JCR]　[WOS]
Tsang TJ, Hsueh YC, Wei EI, Lundy DJ, Cheng B, Chen YT, Wang SS , Hsieh PC*. Subcellular Localization of Survivin Determines Its Function in Cardiomyocytes. Theranostics. 7(18), 4577-4590, 2017-10. [JCR]　[WOS]
Chou IW, Cheng YH, Chen YR, Hsieh PC*, King K*. Fenugreek Compound (N55) Lowers Plasma Glucose through the Enhancement of Response of Physiological Glucagon-like peptide-1. Scientific Reports. 7(1), 12265, 2017-09. [JCR]　[WOS]
Chen HC, Chin YF, Lundy DJ, Liang CT, Chi YH, Kuo P, Hsieh PC*. Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis. Scientific Reports. 7(1), 7372, 2017-08. [JCR]　[WOS]
Cheng YY, Yan YT, Lundy DJ, Lo AH, Wang YP, Ruan SC, Lin PJ, Hsieh PC*. Reprogramming-derived gene cocktail increases cardiomyocyte proliferation for heart regeneration. EMBO molecular medicine. 992), 251-264, 2017-02. [JCR]　[WOS]
Soong BW, Syu SH, Wen CH, Ko HW, Wu ML, Hsieh PC, Hwang SM, Lu HE. Generation of induced pluripotent stem cells from a patient with spinocerebellar ataxia type 3. Stem Cell Research. 18, 29-32, 2017-01. [JCR]　[WOS]
Wu PJ, Cheng B, Roffler SR*, Lundy DJ, Yen CY, Chen P, Lai JJ, Pun SH, Stayton PS, Hsieh PC*. Reloadable multidrug capturing delivery system for targeted ischemic disease treatment. Science translational medicine. 8(365), 365ra160, 2016-11. [JCR]　[WOS]
Cheng B, Toh EK, Chen KH, Chang YC, Hu CM, Wu HC, Chau LY, Chen P, Hsieh PC*. Biomimicking Platelet-Monocyte Interactions as a Novel Targeting Strategy for Heart Healing. Advanced Healthcare Materials. 5(20), 2686-2697, 2016-10. [JCR]　[WOS]
Wang YL, Lin SP, Hsieh PC, Hung SC. Concomitant beige adipocyte differentiation upon induction of mesenchymal stem cells into brown adipocytes. Biochemical and Biophysical Research Communications. 478(2), 689-695, 2016-09. [JCR]　[WOS]
Lundy DJ, Chen KH, Toh EK, Hsieh PC*. Distribution of Systemically Administered Nanoparticles Reveals a Size-Dependent Effect Immediately following Cardiac Ischaemia-Reperfusion Injury. Scientific Reports. 6(1), 25613, 2016-05. [JCR]　[WOS]
Chang MY, Huang TT, Chen CH, Cheng B, Hwang SM, Hsieh PC*. Injection of Human Cord Blood Cells With Hyaluronan Improves Postinfarction Cardiac Repair in Pigs. STEM CELLS Translational Medicine. 5(1), 56-66, 2016-01. [JCR]　[WOS]
Wu JM, Hsueh YC, Ch'ang HJ, Luo CY, Wu LW, Nakauchi H, Hsieh PC. Circulating cells contribute to cardiomyocyte regeneration after injury. Circulation research. 116(4), 633-641 (One of the best 10 papers in Circ Res 2015), 2015. [JCR]　[WOS]
Lee DS, Chen JH, Lundy DJ, Liu CH, Hwang SM, Pabon L, Shieh RC, Chen CC, Wu SN, Yan YT, Lee ST, Chiang PM, Chien S, Murry CE, Hsieh PC. Defined MicroRNAs Induce Aspects of Maturation in Mouse and Human Embryonic-Stem-Cell-Derived Cardiomyocytes. Cell reports. 12(12), 1960-1967 (Cover story), 2015. [JCR]　[WOS]
Chen CL, Wang LJ, Yan YT, Hsu HW, Su HL, Chang FP, Hsieh PC, Hwang SM, Shen CN. Cyclin D1 acts as a barrier to pluripotent reprogramming by promoting neural progenitor fate commitment. FEBS Letters. 588(21), 4008-4017, 2014-11. [JCR]　[WOS]
Lin YD, Ko MC, Wu ST, Li SF, Hu JF, Lai YJ, Harn HI, Laio IC, Yeh ML, Yeh HI, Tang MJ, Chang KC, Su FC, Wei EI, Lee ST, Chen JH, Hoffman AS, Wu WT, Hsieh PC*. A nanopatterned cell-seeded cardiac patch prevents electro-uncoupling and improves the therapeutic efficacy of cardiac repair. Biomaterials Science. 2(4), 567, 2014-04. [JCR]　[WOS]
Chen CH, Chang MY, Wang SS, Hsieh PC*. Injection of autologous bone marrow cells in hyaluronan hydrogel improves cardiac performance after infarction in pigs. American Journal of Physiology-Heart and Circulatory Physiology. 306(7), H1078-H1086, 2014-04. [JCR]　[WOS]
Lai CY, Wu PR, Roffler SR, Lee ST, Hwang SM, Wang SS, Wang K, Hsieh PC*. Clearance Kinetics of Biomaterials Affects Stem Cell Retention and Therapeutic Efficacy. Biomacromolecules. 15(2), 564-573, 2014-02. [JCR]　[WOS]
Tsai MT, Wu HY, Roan JN, Tsai YS, Hsieh PC, Yang YJ, Luo CY. Effect of false lumen partial thrombosis on repaired acute type A aortic dissection. The Journal of Thoracic and Cardiovascular Surgery. 148(5), 2140-2146.e3, 2014-02. [JCR]　[WOS]
Hsueh YC, Wu JM, Yu CK, Wu KK, Hsieh PC. Prostaglandin E2 promotes post-infarction cardiomyocyte replenishment by endogenous stem cells. EMBO molecular medicine. 6(4), 496-503 (Journal highlight), 2014. [JCR]　[WOS]
Liao WY, Li HJ, Chang MY, Tang AC, Hoffman AS, Hsieh PC*. Comprehensive characterizations of nanoparticle biodistribution following systemic injection in mice. Nanoscale. 5(22), 11079-11086, 2013-11. [JCR]　[WOS]
Li HC, Hsieh FJ, Chen CP, Chang MY, Hsieh PC, Chen CC, Hung SU, Wu CC, Chang HC. The hemocompatibility of oxidized diamond nanocrystals for biomedical applications. Scientific Reports. 3(1), 3044, 2013-10. [JCR]　[WOS]
Chang MY, Yang YJ, Chang CH, Tang AC, Liao WY, Cheng FY, Yeh CS, Lai JJ, Stayton PS, Hsieh PC*. Functionalized nanoparticles provide early cardioprotection after acute myocardial infarction. Journal of Controlled Release. 170(2), 287-294, 2013-09. [JCR]　[WOS]
Kuo WS, Hwang SM, Sei HT, Ku YC, Hsu LF, Cheng FY, Hsieh PC*, Yeh CS*. Stabilizer-Free Poly(lactide-co-glycolide) Nanoparticles Conjugated with Quantum Dots as a Potential Carrier Applied in Human Mesenchymal Stem Cells. Journal of the Chinese Chemical Society. 56(5), 940-948, 2013-09. [JCR]　[WOS]
Liu YW, Roan JN, Wang SP, Hwang SM, Tsai MS, Chen JH*, Hsieh PC*. Xenografted human amniotic fluid-derived stem cell as a cell source in therapeutic angiogenesis. International Journal of Cardiology. 168(1), 66-75, 2013-09. [JCR]　[WOS]
Chen CH, Wang SS, Wei EI, Chu TU, Hsieh PC*. Hyaluronan Enhances Bone Marrow Cell Therapy for Myocardial Repair After Infarction. Molecular Therapy. 21(3), 670-679, 2013-03. [JCR]　[WOS]
Tang AC, Hwang GL, Tsai SJ, Chang MY, Tang ZC, Tsai MD, Luo CY, Hoffman AS, Hsieh PC*. Biosafety of Non-Surface Modified Carbon Nanocapsules as a Potential Alternative to Carbon Nanotubes for Drug Delivery Purposes. PLoS ONE. 7(3), e32893, 2012-03. [JCR]　[WOS]
Lin YD, Luo CY, Hu YN, Yeh ML, Hsueh YC, Chang MY, Tsai DC, Wang JN, Tang MJ, Wei EI, Springer ML, Hsieh PC. Instructive nanofiber scaffolds with VEGF create a microenvironment for arteriogenesis and cardiac repair. Science translational medicine. 4(146), 146ra109, 2012. [JCR]　[WOS]
Tang AC, Chang MY, Tang ZC, Li HJ, Hwang GL, Hsieh PC. Treatment of acute thromboembolism in mice using heparin-conjugated carbon nanocapsules. ACS nano. 6(7), 6099-6107, 2012. [JCR]　[WOS]
Tang ZC, Liao WY, Tang AC, Tsai SJ, Hsieh PC*. The enhancement of endothelial cell therapy for angiogenesis in hindlimb ischemia using hyaluronan. Biomaterials. 32(1), 75-86, 2011-01. [JCR]　[WOS]
Chan SS, Li HJ, Hsueh YC, Lee DS, Chen JH, Hwang SM, Chen CY, Shih E, Hsieh PC*. Fibroblast Growth Factor-10 Promotes Cardiomyocyte Differentiation from Embryonic and Induced Pluripotent Stem Cells. PLoS ONE. 5(12), e14414, 2010-12. [JCR]　[WOS]
Wang C, Yan KW, Lin YD, Hsieh PC. Biodegradable Core/Shell Fibers by Coaxial Electrospinning: Processing, Fiber Characterization, and Its Application in Sustained Drug Release. Macromolecules. 43(15), 6389-6397, 2010-07. [JCR]　[WOS]
Lin YD, Yeh ML, Yang YJ, Tsai DC, Chu TY, Shih YY, Chang MY, Liu YW, Tang AC, Chen TY, Luo CY, Chang KC, Chen JH, Wu HL, Hung TK, Hsieh PC. Intramyocardial peptide nanofiber injection improves postinfarction ventricular remodeling and efficacy of bone marrow cell therapy in pigs. Circulation. 122(11 Suppl), S132-41, 2010. [JCR]　[WOS]
Chan SS, Chen JH, Hwang SM, Wang IJ, Li HJ, Lee RT, Hsieh PC*. Salvianolic acid B–vitamin C synergy in cardiac differentiation from embryonic stem cells. Biochemical and Biophysical Research Communications. 387(4), 723-728, 2009-10. [JCR]　[WOS]
Chen CC, Hsieh PC, Wang GM, Chen WC, Yeh ML. The influence of surface morphology and rigidity of the substrata on cell motility. Materials Letters. 63(21), 1872-1875, 2009-08. [JCR]　[WOS]
Feng FY, Wang SP, Su CH, Tsai TL, Wu PC, Shieh DB, Chen JH, Hsieh PC*, Yeh CS*. Stabilizer-free poly(lactide-co-glycolide) nanoparticles for multimodal biomedical probes. Biomaterials. 29(13), 2104-2112, 2008-05. [JCR]　[WOS]
Wang CC, Chen CH, Lin WW, Hwang SM, Hsieh PC, Lai PH, Yeh YC, Chang Y, Sung HW. Direct intramyocardial injection of mesenchymal stem cell sheet fragments improves cardiac functions after infarction. Cardiovascular Research. 77(3), 515-524, 2007-10. [JCR]　[WOS]
Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD, Robbins J, Lee RT. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nature medicine. 13(8), 970-974, 2007. [JCR]　[WOS]
Hsieh PC, Kenagy RG, Mulvihill ER, Jeanette JP, Wang X, Chang CM, Yao Z, Ruzzo WL, Justice S, Hudkins KL, Alpers CE, Berceli S, Clowes AW. Bone morphogenetic protein 4: Potential regulator of shear stress-induced graft neointimal atrophy. Journal of Vascular Surgery. 43(1), 150-158, 2006. [JCR]　[WOS]
Hsieh PC, Davis ME, Gannon J, MacGillivray C, Lee RT. Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers. The Journal of clinical investigation. 116(1), 237-248, 2006. [JCR]　[WOS]
Englesbe MJ, Davies MG, Hawkins SM, Hsieh PC, Daum G, Kenagy RD, Clowes AW. Arterial injury repair in nonhuman primates—the role of PDGF receptor-β. Journal of Surgical Research. 119(1), 80-84, 2004. [JCR]　[WOS]
Englesbe MJ, Hawkins SM, Hsieh PC, Daum G, Kenagy RD, Clowes AW. Concomitant blockade of platelet-derived growth factor receptors α and β induces intimal atrophy in baboon PTFE grafts. Journal of Vascular Surgery. 39(2), 440-446, 2004. [JCR]　[WOS]
Hsieh PC, Wang SS, KO WJ, Han YY, Chu SH. Successful resuscitation of acute massive pulmonary embolism with extracorporeal membrane oxygenation and open embolectomy. The Annals of Thoracic Surgery. 72(1), 266-267, 2002. [JCR]　[WOS]

Book 1

Hwang GL, Tang AC, (Hsieh PC)* Conjugated carbon nanocapsules. , 2015.