Research Findings
Journal 16
- Ueki H#*, (Wang IH#), Kiso M, Horie K, Iida S, Mine S, Ujie M, Hsu HW, Wu CHH, Imai M, Suzuki T, Kamitani W, Kawakami E, Kawaoka Y*. Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology. Nature Communications. 16(1), 455, 2025-01. [JCR]
- Sun CP, Chiu CW, Wu PY, Tsung SI, Lee IJ, Hu CW, Hsu MF, Kuo TJ, Lan YH, Chen LY, Ng HY, Chung MJ, Liao HN, Tseng SC, Lo CH, Chen YJ, Liao CC, Chang CS, Liang JJ, Draczkowski P, Puri S, Chang YC, Huang JS, Chen CC, Kau JH, Chen YH, Liu WC, Wu HC, Hsu STD, (Wang IH*), Tao MH*. Development of AAV-delivered broadly neutralizing anti-human ACE2 antibodies against SARS-CoV-2 variants. Molecular Therapy. 31(11), 3322-3336, 2023-11. [JCR] [WOS]
- Yang CF*, Liao CC, Hsu HW, Liang JJ, Chang CS, Ko HY, Chang RH, Tang WC, Chang MH, (Wang IH*), Lin YL*. Human ACE2 protein is a molecular switch controlling the mode of SARS-CoV-2 transmission. Journal of Biomedical Science. 30(1), 87, 2023-10-12. [JCR] [WOS]
- Lee IJ, Lan YH, Wu PY, Wu YW, Chen YH, Tseng SC, Kuo TJ, Sun CP, Jan JT, Ma HH, Liao CC, Liang JJ, Ko HY, Chang CS, Liu WC, Ko YA, Chen YH, Sie ZL, Tsung SI, Lin YL, (Wang IH), Tao MH. A receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern. Emerging microbes & infections. 12(1), 2149353, 2023. [JCR] [WOS]
- Lee IJ, Sun CP, Wu PY, Lan YH, (Wang IH), Liu WC, Yuan JPY, Chang YW, Tseng SC, Tsung SI, Chou YC, Kumari M, Lin YS, Chen HF, Chen TY, Lin CC, Chiu CW, Hsieh CH, Chuang CY, Cheng CM, Lin HT, Chen WY, Hsu FF, Hong MH, Liao CC, Chang CS, Liang JJ, Ma HH, Chiang MT, Liao HN, Ko HY, Chen LY, Ko YA, Yu PY, Yang TJ, Chiang PC, Hsu ST, Lin YL, Lee CC, Wu HC, Tao MH*. A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants. JOURNAL OF BIOMEDICAL SCIENCE. 29, 49, 2022-07-07. [JCR] [WOS]
- Sun CP#, Jan JT#, (Wang IH#), Ma HH, Ko HY, Wu PY, Kuo TJ, Liao HN, Lan YH, Sie ZL, Chen YH, Ko YA, Liao CC, Chen LY, Lee IJ, Tsung SI, Lai YJ, Chiang MT, Liang JJ, Liu WC, Wang JR, Yuan JPY, Lin YS, Tsai YC, Hsieh SL, Li CW, Wu HC, Ko TM, Lin YL*, Tao MH* (#Equal Contribution). Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19. PLOS Pathogens. 17(8), e1009758, 2021. [JCR] [WOS]
- Zhong G, Fan S, Hatta M, Nakatsu S, Walters KB, Lopes TJS, (Wang J IH), Ozawa M, Karasin A, Li Y, Tong S, Donis RO, Neumann G, Kawaoka Y*. Mutations in the Neuraminidase-Like Protein of Bat Influenza H18N11 Virus Enhance Virus Replication in Mammalian Cells, Mice, and Ferrets. Journal of Virology. 94(5), e01416-19, 2020-03. [JCR] [WOS]
- Ueki H, (Wang IH), Zhao D, Gunzer M, Kawaoka Y*. Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESS. Nature Protocols. 15, 1041–1065, 2020. [JCR] [WOS]
- Yasuhara A, Yamayoshi S, Kiso M, Sakai-Tagawa Y, Koga M, Adachi E, Kikuchi T, (Wang IH), Yamada S, Kawaoka Y*. Antigenic drift originating from changes to the lateral surface of the neuraminidase head of influenza A virus. Nature microbiology. 4(6), 1024-1034, 2019-06. [JCR] [WOS]
- (Wang IH), Burckhardt CJ, Yakimovich A, Greber UF*. Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton. VIRUSES-BASEL. 10(4), pii: E166, 2018. [JCR] [WOS]
- Ueki H#, (Wang IH#), Fukuyama S, Katsura H, da Silva Lopes TJ, Neumann G, Kawaoka Y* (# Equal contribution). In vivo imaging of the pathophysiological changes and neutrophil dynamics in influenza virus-infected mouse lungs. Proceedings of the National Academy of Sciences of the United States of America. 115(28), E6622-E6629, 2018. [JCR] [WOS]
- (Wang IH), Burckhardt CJ, Yakimovich A, Morf MK, Greber UF*. The nuclear export factor CRM1 controls juxta-nuclear microtubule-dependent virus transport. Journal of cell science. 130(13), 2185-2195, 2017. [JCR] [WOS]
- Yakimovich A, Andriasyan V, Witte R, (Wang IH), Prasad V, Suomalainen M, Greber UF*. Plaque2.0-A High-Throughput Analysis Framework to Score Virus-Cell Transmission and Clonal Cell Expansion. PloS one. 10(9), e0138760, 2015. [JCR] [WOS]
- (Wang IH), Suomalainen M, Andriasyan V, Kilcher S, Mercer J, Neef A, Luedtke NW, Greber UF*. Tracking Viral Genomes in Host Cells at Single-Molecule Resolution. Cell Host & Microbe. 14(4), 468-480, 2013. [JCR] [WOS]
- Strunze S, Engelke MF, (Wang IH), Puntener D, Boucke K, Schleich S, Way M, Schoenenberger P, Burckhardt CJ, Greber UF*. Kinesin-1-Mediated Capsid Disassembly and Disruption of the Nuclear Pore Complex Promote Virus Infection. Cell Host & Microbe. 10(3), 210-223, 2011. [JCR] [WOS]
- Emerson V, Holtkotte D, Pfeiffer T, (Wang IH), Schnoelzer M, Kempf T, Bosch V*. Identification of the Cellular Prohibitin 1/Prohibitin 2 Heterodimer as an Interaction Partner of the C-Terminal Cytoplasmic Domain of the HIV-1 Glycoprotein. Journal of Virology. 84(3), 1355-1365, 2009. [JCR] [WOS]