Research Findings
Inst. of Biomedical Sciences - 何彥君 Ho, Yen-Chun
Journal 22
- Hamdin CD, Wu ML, Chen CM, Ho YC, Jiang WC, Gung PY, Ho HH, Chuang HC, Tan TH, Yet SF. Dual-Specificity Phosphatase 6 Deficiency Attenuates Arterial-Injury-Induced Intimal Hyperplasia in Mice. International journal of molecular sciences. 24(24), 17136, 2023.
- Mahamud MR, Geng X, Chen L, Ahmed Z, Ho Y, Srinivasan RS. GATA2 regulates blood/lymph separation in a platelet-dependent and lymphovenous valve-independent manner. Microcirculation (New York, N.Y. : 1994). 30(2-3), e12787, 2023.
- Chen CM, Gung PY, Ho YC, Hamdin CD, Yet SF. Probucol treatment after traumatic brain injury activates BDNF/TrkB pathway, promotes neuroregeneration and ameliorates functional deficits in mice. British journal of pharmacology. 180(20), 2605-2622, 2023.
- Ho YC, Geng X, O'Donnell A, Ibarrola J, Fernandez-Celis A, Varshney R, Subramani K, Azartash-Namin ZJ, Kim J, Silasi R, Wylie-Sears J, Alvandi Z, Chen L, Cha B, Chen H, Xia L, Zhou B, Lupu F, Burkhart HM, Aikawa E, Olson LE, Ahamed J, Lopez-Andres N, Bischoff J, Yutzey KE, Srinivasan RS. PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circulation research. 133(6), 463-480, 2023.
- Geng X, Ho YC, Srinivasan RS. Biochemical and mechanical signals in the lymphatic vasculature. Cellular and molecular life sciences : CMLS. 78(16), 5903-5923, 2021.
- Chen CM, Wu ML, Ho YC, Gung PY, Tsai MH, Orekhov AN, Sobenin IA, Lin P, Yet SF. Exposure to Zinc Oxide Nanoparticles Disrupts Endothelial Tight and Adherens Junctions and Induces Pulmonary Inflammatory Cell Infiltration. International journal of molecular sciences. 21(10), 21103437, 2020.
- Ho YC, Srinivasan RS. Lymphatic Vasculature in Energy Homeostasis and Obesity. Frontiers in physiology. 11, 3, 2020.
- Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS. S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI insight. 5(14), 137652, 2020.
- Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS. YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development (Cambridge, England). 147(23), 195453, 2020.
- Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS. GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development (Cambridge, England). 146(21), 184218, 2019.
- Chen CH, Ho YC, Ho HH, Liang LY, Jiang WC, Lee GL, Lee JK, Hsu YJ, Kuo CC, Wu KK, Yet SF. Tryptophan metabolite 5-methoxytryptophan ameliorates arterial denudation-induced intimal hyperplasia via opposing effects on vascular endothelial and smooth muscle cells. Aging. 11(19), 8604-8622, 2019.
- Lai YL, Lin CY, Jiang WC, Ho YC, Chen CH, Yet SF. Loss of heme oxygenase-1 accelerates mesodermal gene expressions during embryoid body development from mouse embryonic stem cells. Redox biology. 15, 51-61, 2018.
- Ho YC, Wu ML, Su CH, Chen CH, Ho HH, Lee GL, Lin WS, Lin WY, Hsu YJ, Kuo CC, Wu KK, Yet SF. A Novel Protective Function of 5-Methoxytryptophan in Vascular Injury. Scientific reports. 6, 25374, 2016.
- Ho YC, Wu ML, Gung PY, Chen CH, Kuo CC, Yet SF. Heme oxygenase-1 deficiency exacerbates angiotensin II-induced aortic aneurysm in mice. Oncotarget. 7(42), 67760-67776, 2016.
- Wu ML, Chen CH, Lin YT, Jheng YJ, Ho YC, Yang LT, Chen L, Layne MD, Yet SF. Divergent signaling pathways cooperatively regulate TGFbeta induction of cysteine-rich protein 2 in vascular smooth muscle cells. Cell communication and signaling : CCS. 12, 22, 2014.
- Chen CH, Ho YC, Ho HH, Chang IC, Kirsch KH, Chuang YJ, Layne MD, Yet SF. Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration. Cardiovascular research. 100(3), 461-71, 2013.
- Wu ML, Ho YC, Yet SF. A central role of heme oxygenase-1 in cardiovascular protection. Antioxidants & redox signaling. 15(7), 1835-46, 2011.
- Wu ML, Ho YC, Lin CY, Yet SF. Heme oxygenase-1 in inflammation and cardiovascular disease. American journal of cardiovascular disease. 1(2), 150-8, 2011.
- Ho YC, Wang S. Adult neurogenesis is reduced in the dorsal hippocampus of rats displaying learned helplessness behavior. Neuroscience. 171(1), 153-61, 2010.
- Peng HY, Cheng YW, Lee SD, Ho YC, Chou D, Chen GD, Cheng CL, Hsu TH, Tung KC, Lin TB. Glutamate-mediated spinal reflex potentiation involves ERK 1/2 phosphorylation in anesthetized rats. Neuropharmacology. 54(4), 686-98, 2008.
- Chen KJ, Chen LW, Liao JM, Chen CH, Ho YC, Ho YC, Cheng CL, Lin JJ, Huang PC, Lin TB. Effects of a calcineurin inhibitor, tacrolimus, on glutamate-dependent potentiation in pelvic-urethral reflex in anesthetized rats. Neuroscience. 138(1), 69-76, 2006.
- Lin SY, Chen GD, Liao JM, Pan SF, Chen MJ, Chen JC, Peng HY, Ho YC, Ho YC, Huang PC, Lin JJ, Lin TB. Estrogen modulates the spinal N-methyl-D-aspartic acid-mediated pelvic nerve-to-urethra reflex plasticity in rats. Endocrinology. 147(6), 2956-63, 2006.