Academia Sinica Life Science Library -- Research Findings

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Research Findings

Inst. of Biomedical Sciences - 陳煥源 Chen, Huan-Yuan

Journal 29

Wang SF, Tseng SP, Loh EW, Wang WH, Li MC, Chen KH, Tsai WC, Lee YM, Chen HY, Liu FT, Arthur Chen YM, Huang JC. Generation and characterization of new monoclonal antibodies against swine origin 2009 influenza A (H1N1) virus and evaluation of their prophylactic and therapeutic efficacy in a mouse model. Developmental and comparative immunology. 67, 8-17, 2017. [JCR]　[WOS]
Chen HL, Chiang PC, Lo CH, Lo YH, Hsu DK, Chen HY, Liu FT. Galectin-7 Regulates Keratinocyte Proliferation and Differentiation through JNK-miR-203-p63 Signaling. The Journal of investigative dermatology. 136(1), 182-191, 2016-01. [JCR]　[WOS]
Huang WC, Chen HL, Chen HY, Peng KP, Lee Y, Huang LM, Chang LY, Liu FT. Galectin-3 and Its Genetic Variation rs4644 Modulate Enterovirus 71 Infection. PloS one. 11(12), e0168627, 2016. [JCR]　[WOS]
Tian J, Yang G, Chen HY, Hsu DK, Tomilov A, Olson KA, Dehnad A, Fish SR, Cortopassi G, Zhao B, Liu FT, Gershwin ME, Torok NJ, Jiang JX. Galectin-3 regulates inflammasome activation in cholestatic liver injury. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30(12), 4202-4213, 2016. [JCR]　[WOS]
Chen HY, Chiang DM, Lin ZJ, Hsieh CC, Yin GC, Weng IC, Guttermann P, Werner S, Henzler K, Schneider G, Lai LJ, Liu FT. Nanoimaging granule dynamics and subcellular structures in activated mast cells using soft X-ray tomography. Scientific reports. 6, 34879, 2016. [JCR]　[WOS]
Li JR, Ross SS, Liu Y, Liu YX, Wang KH, Chen HY, Liu FT, Laurence TA, Liu GY. Engineered Nanostructures of Haptens Lead to Unexpected Formation of Membrane Nanotubes Connecting Rat Basophilic Leukemia Cells. ACS nano. 9(7), 6738-6746, 2015. [JCR]　[WOS]
Chen HY, Weng IC, Li CS, Wan L, Liu FT. Examination of galectins in phagocytosis. Methods in molecular biology (Clifton, N.J.). 1207, 201-213, 2015. [JCR]
Lai CY, Yeh DW, Lu CH, Liu YL, Huang LR, Kao CY, Chen HY, Huang CY, Chang CH, Luo Y, Xiang R, Chuang TH. Identification of Thiostrepton as a Novel Inhibitor for Psoriasis-like Inflammation Induced by TLR7-9. Journal of immunology. 195(8), 3912-3921, 2015. [JCR]　[WOS]
Wang SF, Tsao CH, Lin YT, Hsu DK, Chiang ML, Lo CH, Chien FC, Chen P, Arthur Chen YM, Chen HY, Liu FT. Galectin-3 promotes HIV-1 budding via association with Alix and Gag p6. Glycobiology. 24(11), 1022-1035, 2014. [JCR]　[WOS]
Chen HY, Weng IC, Hong MH, Liu FT. Galectins as bacterial sensors in the host innate response. Current Opinion in Microbiology. 17C, 75-81, 2014. [JCR]　[WOS]
Fermin Lee A, Chen HY, Wan L, Wu SY, Yu JS, Huang AC, Miaw SC, Hsu DK, Wu-Hsieh BA, Liu FT. Galectin-3 modulates Th17 responses by regulating dendritic cell cytokines. American Journal of Pathology. 183(4), 1209-1222, 2013. [JCR]　[WOS]
Cheng CL, Hou HA, Lee MC, Liu CY, Jhuang JY, Lai YJ, Lin CW, Chen HY, Liu FT, Chou WC, Chen CY, Tang JL, Yao M, Huang SY, Ko BS, Wu SJ, Tsay W, Tien HF. Higher bone marrow LGALS3 expression is an independent unfavorable prognostic factor for overall survival in patients with acute myeloid leukemia. Blood. 121(16), 3172-3180, 2013. [JCR]　[WOS]
Liu W, Hsu DK, Chen HY, Yang RY, Carraway KL 3rd, Isseroff RR, Liu FT. Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. The Journal of investigative dermatology. 132(12), 2828-2837, 2012. [JCR]　[WOS]
Larsen L, Chen HY, Saegusa J, Liu FT. Galectin-3 and the skin. Journal of dermatological science. 64(2), 85-91, 2011. [JCR]　[WOS]
Liu FT, Yang RY, Saegusa J, Chen HY, Hsu DK. Galectins in regulation of apoptosis. Advances in experimental medicine and biology. 705, 431-442, 2011. [JCR]
Koehne JE, Stevens RM, Zink T, Deng Z, Chen H, Weng IC, Liu FT, Liu GY. Using carbon nanotube probes for high-resolution three-dimensional imaging of cells. Ultramicroscopy. 111(8), 1155-1162, 2011. [JCR]　[WOS]
Hsu DK, Chernyavsky AI, Chen HY, Yu L, Grando SA, Liu FT. Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. The Journal of investigative dermatology. 129(3), 573-583, 2009. [JCR]　[WOS]
Saegusa J, Hsu DK, Chen HY, Yu L, Fermin A, Fung MA, Liu FT. Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. The American journal of pathology. 174(3), 922-931, 2009. [JCR]　[WOS]
Chen HY, Fermin A, Vardhana S, Weng IC, Lo KF, Chang EY, Maverakis E, Yang RY, Hsu DK, Dustin ML, Liu FT. Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proceedings of the National Academy of Sciences of the United States of America. 106(34), 14496-14501, 2009. [JCR]　[WOS]
Hsu DK, Chen HY, Liu FT. Galectin-3 regulates T-cell functions. Immunological reviews. 230(1), 114-127, 2009. [JCR]　[WOS]
Deng Z, Zink T, Chen HY, Walters D, Liu FT, Liu GY. Impact of actin rearrangement and degranulation on the membrane structure of primary mast cells: a combined atomic force and laser scanning confocal microscopy investigation. Biophysical journal. 96(4), 1629-1639, 2009. [JCR]　[WOS]
Zink T, Deng Z, Chen H, Yu L, Liu FT, Liu GY. High-resolution three-dimensional imaging of the rich membrane structures of bone marrow-derived mast cells. Ultramicroscopy. 109(1), 22-31, 2008. [JCR]　[WOS]
Lulevich V, Zink T, Chen HY, Liu FT, Liu GY. Cell mechanics using atomic force microscopy-based single-cell compression. Langmuir : the ACS journal of surfaces and colloids. 22(19), 8151-8155, 2006. [JCR]　[WOS]
Chen HY, Sharma BB, Yu L, Zuberi R, Weng IC, Kawakami Y, Kawakami T, Hsu DK, Liu FT. Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. Journal of immunology. 177(8), 4991-4997, 2006. [JCR]　[WOS]
Chen HY, Liu FT, Yang RY. Roles of galectin-3 in immune responses. Archivum immunologiae et therapiae experimentalis. 53(6), 497-504, 2005. [JCR]　[WOS]
Zuberi RI, Hsu DK, Kalayci O, Chen HY, Sheldon HK, Yu L, Apgar JR, Kawakami T, Lilly CM, Liu FT. Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. The American journal of pathology. 165(6), 2045-2053, 2004. [JCR]　[WOS]
Yang RY, Hsu DK, Yu L, Chen HY, Liu FT. Galectin-12 is required for adipogenic signaling and adipocyte differentiation. The Journal of biological chemistry. 279(28), 29761-29766, 2004. [JCR]　[WOS]
Sheu JJ, Cheng T, Chen HY, Lim C, Chang TW. Comparative effects of human Ig alpha and Ig beta in inducing autoreactive antibodies against B cells in mice. Journal of immunology. 170(3), 1158-1166, 2003. [JCR]　[WOS]
Chen HY, Liu FT, Hou CM, Huang JS, Sharma BB, Chang TW. Monoclonal antibodies against the C(epsilon)mX domain of human membrane-bound IgE and their potential use for targeting IgE-expressing B cells. International archives of allergy and immunology. 128(4), 315-324, 2002. [JCR]　[WOS]

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