Academia Sinica Life Science Library -- Publications

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Publications

Inst. of Biomedical Sciences - 徐松錕 Shyue, Song-Kun

Journal 108

Chen Shu-Fen, Wu Chun-Hu, Lee Yen-Ming, Tam Kabik, Liou Jun-Yang, Shyue Song-Kun. Surf4 collaborates with derlin-2 and derlin-1 to mediate cyclooxygenase-2 translocation to the cytosol for degradation. Journal of Cell Science. 136(18), 1-12, 2023-09-28. [JCR]　[WOS]
Lien CF, Lin CS, Shyue SK, Hsieh PS, Chen SJ, Lin YT, Chien S, Tsai MC. Peroxisome proliferator-activated receptor delta improves the features of atherosclerotic plaque vulnerability by regulating smooth muscle cell phenotypic switching. British journal of pharmacology. On line published, On line-on line, 2023. [JCR]　[WOS]
Chuang CK, Chen SF, Su YH, Chen WH, Lin WM, Wang IC, Shyue SK. The Role of SCL Isoforms in Embryonic Hematopoiesis. International journal of molecular sciences. 24(7), 6427-6427, 2023. [JCR]　[WOS]
Chou PC, Liu CM, Weng CH, Yang KC, Cheng ML, Lin YC, Yang RB, Shyu BC, (Shyue SK), Liu JD, Chen SP, Hsiao M, Hu YF. Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes. Circulation research. 131(1), 6-20, 2022. [JCR]　[WOS]
Chen CH, Leu SJ, Hsu CP, Pan CC, (Shyue SK*), Lee TS*. Atypical antipsychotic drugs deregulate the cholesterol metabolism of macrophage-foam cells by activating NOX-ROS-PPARγ-CD36 signaling pathway. Metabolism: clinical and experimental. 123, 154847, 2021. [JCR]　[WOS]
Lien CC, Chen CH, Lee YM, Guo BC, Cheng LC, Pan CC, Shyue SK*, Lee TS*. The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux. Journal of cellular and molecular medicine. 23(10), 6611-6621, 2019-10. [JCR]　[WOS]
Wu CH, Chen CC, Hung TH, Chuang YC, Chao M, Shyue SK*, Chen SF*. Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage. Journal of biomedical science. 26(1), 53, 2019-07. [JCR]　[WOS]
Wu YJ, Ko BS, Liang SM, Lu YJ, Jan YJ, Jiang SS, Shyue SK, Chen L, Liou JY. ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma. Cell death & disease. 10(6), 408, 2019-05. [JCR]　[WOS]
Lin YT, Liang SM, Wu YJ, Wu YJ, Lu YJ, Jan YJ, Ko BS, Chuang YJ, Shyue SK, Kuo CC, Liou JY. Cordycepin Suppresses Endothelial Cell Proliferation, Migration, Angiogenesis, and Tumor Growth by Regulating Focal Adhesion Kinase and p53. Cancers. 11(2), 2019-02. [JCR]　[WOS]
Chen Chia-Hui, Shyue Song-Kun, Hsu Chiao-Po, Lee Tzong-Shyuan. Atypical Antipsychotic Drug Olanzapine Deregulates Hepatic Lipid Metabolism and Aortic Inflammation and Aggravates Atherosclerosis. Cellular Physiology and Biochemistry. 50(4) 1216-1229, 2018. [JCR]　[WOS]
Liu Tzu-An, Jan Yee-Jee, Ko Bor-Sheng, Wu Yi-Ju, Lu Yi-Jhu, Liang Shu-Man, Liu Chia-Chia, Chen Shyh-Chang, Wang John, Shyue Song-Kun, Liou Jun-Yang. Correction: Regulation of Aldo-keto-reductase family 1 B10 by 14-3-3ε and their prognostic impact of hepatocellular carcinoma. Oncotarget. 9(79), 2018. [JCR]　[WOS]
Tsai TH, Tam K, Chen SF, Liou JY, Tsai YC, Lee YM, Huang TY, Shyue SK*. Deletion of caveolin-1 attenuates LPS/GalN-induced acute liver injury in mice. Journal of cellular and molecular medicine. 22(11), 5573-5582, 2018. [JCR]　[WOS]
Liang SM, Lu YJ, Ko BS, Jan YJ, Shyue SK, Yet SF, Liou JY. Cordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity. Scientific reports. 7, 43930, 2017. [JCR]　[WOS]
Hou HH, Liao YJ, Hsiao SH, Shyue SK, Lee TS. Corrigendum: Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase. Scientific reports. 7, 46877, 2017. [JCR]　[WOS]
Hung TH, Shyue SK, Wu CH, Chen CC, Lin CC, Chang CF, Chen SF. Deletion or inhibition of soluble epoxide hydrolase protects against brain damage and reduces microglia-mediated neuroinflammation in traumatic brain injury. Oncotarget. 8(61), 103236-103260, 2017. [JCR]　[WOS]
Wu CH, Shyue SK, Hung TH, Wen S, Lin CC, Chang CF, Chen SF. Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage. Journal of neuroinflammation. 14(1), 230, 2017. [JCR]　[WOS]
Tsai MJ, Huang CT, Huang YS, Weng CF, Shyue SK, Huang MC, Liou DY, Lin YR, Cheng CH, Kuo HS, Lin Y, Lee MJ, Huang WH, Huang WC, Cheng H. Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair. Journal of biomedical science. 24(1), 34, 2017. [JCR]　[WOS]
Hsu CP, Zhao JF, Lin SJ, Shyue SK, Guo BC, Lu TM, Lee TS. Asymmetric Dimethylarginine Limits the Efficacy of Simvastatin Activating Endothelial Nitric Oxide Synthase. Journal of the American Heart Association. 5(4), e003327, 2016. [JCR]　[WOS]
Zhao JF, Hsiao SH, Hsu MH, Pao KC, Kou YR, Shyue SK, Lee TS. Di-(2-ethylhexyl) phthalate accelerates atherosclerosis in apolipoprotein E-deficient mice. Archives of toxicology. 90(1), 181-90, 2016. [JCR]　[WOS]
Zhao JF, Shyue SK, Lee TS. Excess Nitric Oxide Activates TRPV1-Ca(2+)-Calpain Signaling and Promotes PEST-dependent Degradation of Liver X Receptor alpha. International journal of biological sciences. 12(1), 18-29, 2016. [JCR]　[WOS]
Lee KI, Chiang CW, Lin HC, Zhao JF, Li CT, Shyue SK, Lee TS. Maternal exposure to di-(2-ethylhexyl) phthalate exposure deregulates blood pressure, adiposity, cholesterol metabolism and social interaction in mouse offspring. Archives of toxicology. 90(5), 1211-24, 2016. [JCR]　[WOS]
Ma YD, Thiyagarajan V, Tsai MJ, Lue SI, Chia YC, Shyue SK, Weng CF. Pyrogallol abates VSMC migration via modulation of Caveolin-1, matrix metalloproteinase and intima hyperplasia in carotid ligation mouse. Environmental toxicology and pharmacology. 48, 63-75, 2016. [JCR]　[WOS]
Lee KI, Lee HT, Lin HC, Tsay HJ, Tsai FC, Shyue SK, Lee TS. Role of transient receptor potential ankyrin 1 channels in Alzheimer\'s disease. Journal of neuroinflammation. 13(1), 92, 2016. [JCR]　[WOS]
Huang CY, Shih CM, Tsao NW, Lin YW, Shih CC, Chiang KH, Shyue SK, Chang YJ, Hsieh CK, Lin FY. The GroEL protein of Porphyromonas gingivalis regulates atherogenic phenomena in endothelial cells mediated by upregulating toll-like receptor 4 expression. American journal of translational research. 8(2), 384-404, 2016. [JCR]　[WOS]
Zhao JF, Shyue SK, Kou YR, Lu TM, Lee TS. Transient Receptor Potential Ankyrin 1 Channel Involved in Atherosclerosis and Macrophage-Foam Cell Formation. International journal of biological sciences. 12(7), 812-23, 2016. [JCR]　[WOS]
Ou DL, Shyue SK, Lin LI, Feng ZR, Liou JY, Fan HH, Lee BS, Hsu C, Cheng AL. Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma. Oncotarget. 6(29), 27953-27965, 2015. [JCR]　[WOS]
Tsai YC, Tsai TH, Chang CP, Chen SF, Lee YM, Shyue SK. Linear correlation between average fluorescence intensity of green fluorescent protein and the multiplicity of infection of recombinant adenovirus. Journal of biomedical science. 22, 31, 2015. [JCR]　[WOS]
Liu TA, Jan YJ, Ko BS, Wu YJ, Lu YJ, Liang SM, Liu CC, Chen SC, Wang J, Shyue SK, Liou JY. Regulation of aldo-keto-reductase family 1 B10 by 14-3-3epsilon and their prognostic impact of hepatocellular carcinoma. Oncotarget. 6(36), 38967-38982, 2015. [JCR]　[WOS]
Cheng YT, Yeih DF, Liang SM, Chien CY, Yu YL, Ko BS, Jan YJ, Kuo CC, Sung LY, Shyue SK, Chen MF, Yet SF, Wu KK, Liou JY. Rho-associated kinase inhibitors promote the cardiac differentiation of embryonic and induced pluripotent stem cells. International journal of cardiology. 201, 441-448, 2015. [JCR]　[WOS]
Hou HH, Liao YJ, Hsiao SH, Shyue SK, Lee TS. Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase. Scientific reports. 5, 13524, 2015. [JCR]　[WOS]
Lin FY, Huang CY, Lu HY, Shih CM, Tsao NW, Shyue SK, Lin CY, Chang YJ, Tsai CS, Lin YW, Lin SJ. The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization. Molecular oral microbiology. 30(3), 198-216, 2015. [JCR]　[WOS]
Guo BC, Wei J, Su KH, Chiang AN, Zhao JF, Chen HY, Shyue SK, Lee TS. Transient receptor potential vanilloid type 1 is vital for (-)-epigallocatechin-3-gallate-mediated activation of endothelial nitric oxide synthase. Molecular nutrition & food research. 59(4), 646-657, 2015. [JCR]　[WOS]
Chang PC, Tsai HW, Chiang MT, Huang PL, Shyue SK, Chau LY. TRC8 downregulation contributes to the development of non-alcoholic steatohepatitis by exacerbating hepatic endoplasmic reticulum stress. Biochimica et Biophysica Acta-Molecular Basis of Disease. 1852(11), 2339-2351, 2015. [JCR]　[WOS]
Tsou CY, Chen CY, Zhao JF, Su KH, Lee HT, Lin SJ, Shyue SK, Hsiao SH, Lee TS. Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis. Acta physiologica. 210(4), 799-810, 2014-04. [JCR]　[WOS]
Liu CC, Jan YJ, Ko BS, Wu YM, Liang SM, Chen SC, Lee YM, Liu TA, Chang TC, Wang J, Shyue SK, Sung LY, Liou JY. 14-3-3sigma induces heat shock protein 70 expression in hepatocellular carcinoma. BMC cancer. 14, 425, 2014. [JCR]　[WOS]
Zhao JF, (Shyue SK), Lin SJ, Wei J, Lee TS. Excess nitric oxide impairs LXR(alpha)-ABCA1-dependent cholesterol efflux in macrophage foam cells. Journal of cellular physiology. 229(1), 117-125, 2014. [JCR]　[WOS]
Su KH, Lee KI, Shyue SK, Chen HY, Wei J, Lee TS. Implication of transient receptor potential vanilloid type 1 in 14,15-epoxyeicosatrienoic acid-induced angiogenesis. International journal of biological sciences. 10(9), 990-996, 2014. [JCR]　[WOS]
Chou WY, Zhao JF, Chen YM, Lee KI, Su KH, Shyue SK, Lee TS. Role of glycine N-methyltransferase in experimental ulcerative colitis. Journal of gastroenterology and hepatology. 29(3), 494-501, 2014. [JCR]　[WOS]
Su KH, Lin SJ, Wei J, Lee KI, Zhao JF, Shyue SK, Lee TS. The essential role of transient receptor potential vanilloid 1 in simvastatin-induced activation of endothelial nitric oxide synthase and angiogenesis. Acta physiologica. 212(3), 191-204, 2014. [JCR]　[WOS]
Ching LC, Zhao JF, Su KH, (Shyue SK), Hsu CP, Lu TM, Lin SJ, Lee TS. Activation of transient receptor potential vanilloid 1 decreases endothelial nitric oxide synthase phosphorylation at Thr497 by protein phosphatase 2B-dependent dephosphorylation of protein kinase C. ACTA PHYSIOLOGICA. 209(2), 124-135, 2013. [JCR]　[WOS]
Zhao JF, Ching LC, Kou YR, Lin SJ, Wei J, (Shyue SK*), Lee TS*. Activation of TRPV1 prevents OxLDL-induced lipid accumulation and TNF-alpha-induced inflammation in macrophages: role of liver X receptor alpha. Mediators of inflammation. 2013, 925171, 2013. [JCR]　[WOS]
Chen SF, Wu CH, Lee YM, Tam K, Tsai YC, Liou JY, (Shyue SK*). Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex. The Journal of biological chemistry. 288(46), 33462-33469, 2013. [JCR]　[WOS]
Tsai MJ, Weng CF, Yu NC, Liou DY, Kuo FS, Huang MC, Huang WC, Tam K, (Shyue SK*), Cheng H*. Enhanced prostacyclin synthesis by adenoviral gene transfer reduced glial activation and ameliorated dopaminergic dysfunction in hemiparkinsonian rats. Oxidative medicine and cellular longevity. 2013, 649809, 2013. [JCR]　[WOS]
Wei J, Ching LC, Zhao JF, (Shyue SK), Lee HF, Kou YR, Lee TS. Essential role of transient receptor potential vanilloid type 1 in evodiamine-mediated protection against atherosclerosis. ACTA PHYSIOLOGICA. 207(2), 299-307, 2013. [JCR]　[WOS]
Perng DW, Chang TM, Wang JY, Lee CC, Lu SH, (Shyue SK), Lee TS, Kou YR. Inflammatory role of AMP-activated protein kinase signaling in an experimental model of toxic smoke inhalation injury. Critical care medicine. 41(1), 120-132, 2013. [JCR]　[WOS]
Zhao JF, Jim Leu SJ, Shyue SK, Su KH, Wei J, Lee TS. Novel effect of paeonol on the formation of foam cells: promotion of LXRalpha-ABCA1-dependent cholesterol efflux in macrophages. The American journal of Chinese medicine. 41(5), 1079-96, 2013. [JCR]　[WOS]
Su KH, Yu YB, Hou HH, Zhao JF, Kou YR, Cheng LC, (Shyue SK*), Lee TS. AMP-activated protein kinase mediates erythropoietin-induced activation of endothelial nitric oxide synthase. Journal of cellular physiology. 227(8), 3053-3062, 2012-08. [JCR]　[WOS]
Yu YB, Liao YW, Su KH, Chang TM, (Shyue SK), Kou YR, Lee TS*. Prior exercise training alleviates the lung inflammation induced by subsequent exposure to environmental cigarette smoke. ACTA PHYSIOLOGICA. 205(4), 532-540, 2012-08. [JCR]　[WOS]
Chen CY, Ching LC, Liao YJ, Yu YB, Tsou CY, (Shyue SK), Chen YM, Lee TS*. Deficiency of Glycine N-methyltransferase Aggravates Atherosclerosis in Apolipoprotein E-null Mice. MOLECULAR MEDICINE. 18, 744-752, 2012-06. [JCR]　[WOS]
an WY, Lo CH, Chen CC, Wu PY, Roffler SR, (Shyue SK), Tao MH*. Cancer Immunotherapy Using a Membrane-bound Interleukin-12 With B7-1 Transmembrane and Cytoplasmic Domains. MOLECULAR THERAPY. 20(5), 927-937, 2012-05. [JCR]　[WOS]
Zhao JF, Ching LC, Huang YC, Chen CY, Chiang AN, Kou YR, Shyue SK, Lee TS*. Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis. MOLECULAR NUTRITION & FOOD RESEARCH. 56(5), 691-701, 2012-05. [JCR]　[WOS]
Chen CH, Chang WF, Liu CC, Su HY, (Shyue SK), Cheng WT, Chen YE, Wu SC, Du F, Sung LY*, Xu J*. Spatial and temporal distribution of Oct-4 and acetylated H4K5 in rabbit embryos. REPRODUCTIVE BIOMEDICINE ONLINE. 24(4), 433-442, 2012-04. [JCR]　[WOS]
Ching LC, Chen CY, Su KH, Hou HH, (Shyue SK), Kou YR, Lee TS*. Implication of AMP-activated protein kinase in transient receptor potential vanilloid type 1-mediated activation of endothelial nitric oxide synthase. MOLECULAR MEDICINE. 18, 805-815, 2012-03. [JCR]　[WOS]
Hou HH, Hammock BD, Su KH, Morisseau C, Kou YR, Imaoka S, Oguro A, (Shyue SK), Zhao JF, Lee TS*. N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase. CARDIOVASCULAR RESEARCH. 93(1), 120-129, 2012-01. [JCR]　[WOS]
Su KH, (Shyue SK), Kou YR, Ching LC, Chiang AN, Yu YB, Chen CY, Pan CC, Lee TS*. beta Common receptor integrates the erythropoietin signaling in activation of endothelial nitric oxide synthase. Journal of cellular physiology. 226(12), 3330-3339, 2011-12. [JCR]　[WOS]
Liu TA, Jan YJ, Ko BS, Chen SC, Liang SM, Hung YL, Hsu C, Shen TL, Lee YM, Chen PF, Wang J, (Shyue SK*), Liou JY*. Increased expression of 14-3-3beta promotes tumor progression and predicts extrahepatic metastasis and worse survival in hepatocellular carcinoma. The American journal of pathology. 179(6), 2698-2708, 2011-12. [JCR]　[WOS]
Chen CY, (Shyue SK), Ching LC, Su KH, Wu YL, Kou YR, Chiang AN, Pan CC, Lee TS*. Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages. The Journal of nutritional biochemistry. 22(11), 1015-1021, 2011-11. [JCR]　[WOS]
Hsieh YC, Rao YK, Whang-Peng J, Huang CY, (Shyue SK), Hsu SL, Tzeng YM*. Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway. Journal of agricultural and food chemistry. 59(20), 10943-10954, 2011-10. [JCR]　[WOS]
Ching LC, Kou YR, (Shyue SK), Su KH, Wei J, Cheng LC, Yu YB, Pan CC, Lee TS*. Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1. Cardiovascular research. 91(3), 492-501, 2011-08. [JCR]　[WOS]
Tang GJ, Wang HY, Wang JY, Lee CC, Tseng HW, Wu YL, (Shyue SK), Lee TS, Kou YR*. Novel role of AMP-activated protein kinase signaling in cigarette smoke induction of IL-8 in human lung epithelial cells and lung inflammation in mice. Free radical biology & medicine. 50(11), 1492-1502, 2011-06. [JCR]　[WOS]
Bau DT*, Chang CH, Tsai RY, Wang HC, Wang RF, Tsai CW, Yao CH, Chen YS, (Shyue SK), Huang CY. Significant association of caveolin-1 genotypes with bladder cancer susceptibility in Taiwan. The Chinese journal of physiology. 54(3), 153-160, 2011-06. [JCR]　[WOS]
Bau DT, Tsai MH, Tsou YA, Wang CH, Tsai CW, Sun SS, Hua CH, (Shyue SK), Tsai RY. The association of Caveolin-1 genotypes with oral cancer susceptibility in Taiwan. Annals of surgical oncology. 18(5), 1431-1438, 2011-05. [JCR]　[WOS]
Chang CF, Chen SF, Lee TS, Lee HF, Chen SF*, (Shyue SK*). Caveolin-1 deletion reduces early brain injury after experimental intracerebral hemorrhage. The American journal of pathology. 178(4), 1749-1761, 2011-04. [JCR]　[WOS]
Wang CY, Chen JK, Wu YT, Tsai MJ, (Shyue SK), Yang CS, Tzeng SF*. Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury. Journal of biomedical science. 18, 13, 2011-02. [JCR]　[WOS]
Tsai TH, Chen SF, Huang TY, Tzeng CF, Chiang AS, Kou YR, Lee TS, (Shyue SK*). Impaired cd14 and cd36 expression, bacterial clearance, and toll-like receptor 4-myd88 signaling in caveolin-1-deleted macrophages and mice. SHOCK. 35(1), 92-99, 2011-01. [JCR]　[WOS]
Cheng LC, Su KH, Kou YR, (Shyue SK), Ching LC, Yu YB, Wu YL, Pan CC, Lee TS*. α-Lipoic acid ameliorates foam cell formation via liver X receptor α-dependent upregulation of ATP-binding cassette transporters A1 and G1. FREE RADICAL BIOLOGY AND MEDICINE. 50(1), 47-54, 2011-01. [JCR]　[WOS]
Tsai JY, Su KH, (Shyue SK), Kou YR, Yu YB, Hsiao SH, Chiang AN, Wu YL, Ching LC, Lee TS. EGb761 ameliorates the formation of foam cells by regulating the expression of SR-A and ABCA1: role of haem oxygenase-1. CARDIOVASCULAR RESEARCH. 88(1), 415-423, 2010-12. [JCR]　[WOS]
Lee TS, Pan CC, Peng CC, Kou YR, Chen CY, Ching LC, Tsai TH, Chen SF, Lyu PC, (Shyue SK*). Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages. JOURNAL OF CELLULAR BIOCHEMISTRY. 111(1), 104-110, 2010-09. [JCR]　[WOS]
Yang MD, Tsai RY, Liu CS, Chang CH, Wang HC, Tsou YA, Wang CH, Lin CC, (Shyue SK), Bau DT*. Association of Caveolin-1 polymorphisms with colorectal cancer susceptibility in Taiwan. World J Gastrointest Oncol.. 2(8), 326-331, 2010-08. [JCR]　[WOS]
Chen SF, Liou JY, Huang TY, Lin YS, Yeh AL, Tam K, Tsai TH, Wu KK*, (Shyue SK*). Caveolin-1 Facilitates Cyclooxygenase-2 Protein Degradation. JOURNAL OF CELLULAR BIOCHEMISTRY. 109(2), 356-362., 2010-02. [JCR]　[WOS]
Ko B.S., Chang T.C., Chen C.H., Liu C.C., Kuo C.C., Hsu C., Shen Y.C., Shen T.L., Golubovskaya V.M., Chang C.C., (Shyue S.K.*), Liou J.Y.*. Bortezomib suppresses focal adhesion kinase expression via interrupting nuclear factor-kappaB. LIFE SCIENCES. 86(5-6), 199-206, 2010-01. [JCR]　[WOS]
Wu JS, Cheung WM, Tsai YS, Chen YT, Fong WH, Tsai HD, Chen YC, Liou JY, (Shyue SK), Chen JJ, Chen YE, Maeda N, Wu KK, Lin TN. Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation. Circulation. 119(8), 1124-34, 2009-03. [JCR]　[WOS]
Su KH, Tsai JY, Kou YR, Chiang AN, Hsiao SH, Wu YL, Hou HH, Pan CC, (Shyue SK*), Lee TS*. Valsartan regulates the interaction of angiotensin II type 1 receptor and endothelial nitric oxide synthase via Src/PI3K/Akt signalling. Cardiovascular research. 82(3), 468-75, 2009-03. [JCR]　[WOS]
Ko B.S., Chang T.C., (Shyue S.K)., Chen Y.C., Liou J.Y*. An efficient transfection method for mouse embryonic stem cells. GENE THERAPY. 16(1), 154-158, 2009-01. [JCR]　[WOS]
Wang RY, Chung CM, Fann CS, Yang HC, Chen JW, Jong YS, Jou YS, Lo HM, Ho FM, Kang CS, Chen CC, Chang HC, (Shyue SK), Pan WH*. Genome-wide scan for quantitative ACE activity in Taiwan young-onset hypertension study. HUMAN HEREDITY. 65(2), 85-90, 2008-02. [JCR]　[WOS]
Yang CS, Tzou BC, Liu YP, Tsai MJ, (Shyue SK) and Tzeng SF*. Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by the addition of antioxidants and the reduction of intracellular calcium. JOURNAL OF CELLULAR BIOCHEMISTRY. 103(3), 825-834, 2008-02. [JCR]　[WOS]
Chien CT, (Shyue SK), Lai MK*. Bcl-xL augmentation potentially reduces ischemia/reperfusion induced proximal and distal tubular apoptosis and autophagy. Transplantation. 84(9), 1183-1190, 2007-11. [JCR]　[WOS]
Tsai MJ, Weng CF, (Shyue SK), Liou DY, Chen CH, Chiu CW, Yang TH, Pan HA, Liao RI, Kuo HS, Huang MC, Huang WC, Hoffer BJ, Cheng H*. Dual effect of adenovirus-mediated transfer of BMP7 in mixed neuron-glial cultures: neuroprotection and cellular differentiation. J Neurosci Res. 85(13), 2950-2959, 2007-10. [JCR]　[WOS]
Lin SJ, (Shyue SK), Shih MC, Chu TH, Chen YH, Ku HH, Chen JW, Tam KB, Chen YL*. Superoxide dismutase and catalase inhibit oxidized low-density lipoprotein-induced human aortic smooth muscel cell proliferation: role of cell-cycle regulation, mitogen-activated protein kinases, and transcription factors. Atherosclerosis. 190(1), 124-134, 2007-01. [JCR]　[WOS]
Fang YC, Wu JS, Chen JJ, Cheung WM, Tseng PH, Tam KB, (Shyue SK), Chen JJ, Lin TN*. Induction of prostacyclin/PgI(2) synthase expression after cerebral ischemia-reperfusion. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 26, 491-501, 2006-04. [JCR]　[WOS]
Lin TN*, Cheung WM, Wu JS, Chen JJ, Lin H, Chen JJ, Liou JY, (Shyue SK), Wu KK*. 15d-prostaglandin J2 protects brain from ischemia-reperfusion injury. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 26, 481-487, 2006-03. [JCR]　[WOS]
Tsai LK, Tsai MS, (Shyue SK), Hwu WL, Li H*. Adenoviral interneuronal transportation after retrograde gene transfer in mice. MOLECULAR BRAIN RESEARCH. 142(2), 151-155, 2005-12. [JCR]　[WOS]
Chang TC, Huang CJ, Tam K, Chen SF, Tan KT, Tsai MS, Lin TN, (Shyue SK*). Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells. J Biol Chem. 280, 36567-36574, 2005-12. [JCR]　[WOS]
Chien CT, Chang TC, Tsai CY, (Shyue SK*), Lai MK*. Adenovirus-mediated bcl-2 gene transfer inhibits renal ischemia/reperfusion induced tubular oxidative stress and apoptosis. Am J Transplant. 5, 1194-1203, 2005-06. [JCR]　[WOS]
Su YT, Chang HL, (Shyue SK), Hsu SL*. Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Biochem Pharmacol. 70, 229-241, 2005-06. [JCR]　[WOS]
Tsai MJ, (Shyue SK), Weng CF, Chung Y, Liou DY, Huang CT, Kuo HS, Lee MJ, Chang PT, Huang MC, Huang WC, Liou KD, Cheng H*. Effect of enhanced prostacyclin synthesis by adenovirus-mediated transfer on lipopolysaccharide stimulation in neuron-glia cultures. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1042, 338-348, 2005-05. [JCR]　[WOS]
u JY, Aleksic N, Chen SF, Han TJ, (Shyue SK*), Wu KK*. Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: Implication in apoptosis resistance. Exp Cell Res. 306, 75-84, 2005-05. [JCR]　[WOS]
Lin SJ, (Shyue SK*), Hung YY, Chen YH, Ku HH, Chen JW, Tam KB, Chen YL*. Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 25, 334-340, 2005-02. [JCR]　[WOS]
Chang DM, (Shyue SK), Liu SH, Chen YT, Yeh CY, Lai JH, Lee HS, Chen A*. Dual biological functions of an interleukin-1 receptor antagonist-interleukin-10 fusion protein and its suppressive effects on joint inflammation. Immunology. 112, 643-50, 2004-08. [JCR]　[WOS]
Hung SC, Lu CY, (Shyue SK), Liu HC, Ho LL. Lineage differentiation-associated loss of adenoviral susceptibility and Coxsackie-adenovirus receptor expression in human mesenchymal stem cells. Stem Cells. 22, 1321-9, 2004-07. [JCR]　[WOS]
Lin SJ, (Shyue SK*), Liu PL, Chen YH, Ku HH, Chen JW, Tam KB, Chen YL*. Adenovirus-mediated overexpression of catalase attenuates oxLDL-induced apoptosis in human aortic endothelial cells via AP-1 and C-Jun N-terminal kinase/extracellular signal-regulated kinase mitogen-activated protein kinase pathways. J Mol Cell Cardiol. 36, 129-139, 2004-01. [JCR]　[WOS]
Huang CL, Huang NK, (Shyue SK), Chern Y*. Hydrogen peroxide induces loss of dopamine transporter activity: a calcium-dependent oxidative mechanism. J Neurochem. 86, 1247-1259, 2003-09. [JCR]　[WOS]
H. Y. You, S. K. Shyue and G. W. Chen. Analyzing expressed genes of HEK cells cultured with radix acconiti and zingiberis rhizome by gene chips. J Int Chin West Med. 4, 1-6, 2002. [JCR]　[WOS]
H. Lin, T. N. Lin, W. M. Cheung, G. M. Nian, P. H. Tseng, S. F. Chen, J. J. Chen, S. K. Shyue, J. Y. Liou, C. W. Wu and K. K. Wu. Cyclooxygenase-1 and bicistronic cyclooxygenase-1/prostacyclin synthase gene transfer protect against ischemic cerebral infarction. Circulation. 105, 1962-1969, 2002. [JCR]　[WOS]
N. Yu, F. C. Chen, S. Ota, L. B. Jorde, P. Pamilo, L. Patthy, M. Ramsay, T. Jenkins, S. K. Shyue and W. H. Li. Larger genetic differences within africans than between Africans and Eurasians. Genetics. 161, 269-274, 2002. [JCR]　[WOS]
S. H. Juan, T. S. Lee, K. W. Tseng, J. Y. Liou, S. K. Shyue, K. K. Wu and L. Y. Chau. Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation. 104, 1519-1525, 2001. [JCR]　[WOS]
J. Y. Liou, W. G. Deng, D. W. Gilroy, S. K. Shyue and K. K. Wu. Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts. J Biol Chem. 276, 34975-34982, 2001. [JCR]　[WOS]
Wung BS, Cheng JJ, (Shyue SK) and Wang DL. NO modulates monocyte chemotactic protein-1 expression in endothelial cells under cyclic strain. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 21, 1941-1947, 2001. [JCR]　[WOS]
(Shyue SK), Tsai MJ, Liou JY, Willerson JT, Wu KK*. Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer. Circulation. 103(16), 2090-2095, 2001. [JCR]　[WOS]
Liou JY, (Shyue SK), Tsai MJ, Chung CL, Chu KY, Wu KK*. Colocalization of prostacyclin synthase with prostaglandin H synthase-1 (PGHS-1) but not phorbol ester-induced PGHS-2 in cultured endothelial cells. The Journal of biological chemistry. 275(20), 15314-15320, 2000. [JCR]　[WOS]
W. H. Li, S. Boissinot, Y. Tan, S. K. Shyue and D. Hewett-Emmett. Evolutionary genetics of primate color vision. Evolutionary Biology. 32, 151-178, 2000. [JCR]　[WOS]
W. W. Lin*, B. C. Chen, Y. W. Hsu, C. M. Lee and (S. K. Shyue). Modulation of inducible nitric oxide synthase induction by prostaglandin E2 in macrophages: distinct susceptibility in murine J774 and RAW 264.7 macrophages. Prostaglandins Other Lipid Mediat. 58, 87-101, 1999. [JCR]　[WOS]
(S. K. Shyue), S. Boissinot, H. Schneider, I. Sampaio, M. P. Schneider, C. R. Abee, L. Williams, D. Hewett-Emmett, H. G. Sperling, J. A. Cowing, K. S. Dulai, D. M. Hunt and W. H. Li*. Molecular genetics of spectral tuning in New World monkey color vision. J Mol Evol. 46, 697-702, 1998. [JCR]　[WOS]
Boissinot S, Tan Y, (Shyue SK), Schneider H, Sampaio I, Neiswanger K, Hewett-Emmett D, Li WH*. Origins and antiquity of X-linked triallelic color vision systems in New World monkeys. Proceedings of the National Academy of Sciences of the United States of America. 95(23), 13749-54, 1998. [JCR]　[WOS]
(S. K. Shyue), K. H. Ruan, L. H. Wang and K. K. Wu*. Prostacyclin synthase active sites. Identification by molecular modeling-guided site-directed mutagenesis. J Biol Chem. 272, 3657-3662, 1997. [JCR]　[WOS]
(Shyue SK), Hewett-Emmett D, Sperling HG, Hunt DM, Bowmaker JK, Mollon JD, Li WH*. Adaptive evolution of color vision genes in higher primates. SCIENCE. 269(5228), 1265-1267, 1995. [JCR]　[WOS]
(Shyue SK), Li L, Chang BH, Li WH*. Intronic gene conversion in the evolution of human X-linked color vision genes. Molecular biology and evolution. 11(3), 548-51, 1994. [JCR]　[WOS]
Chang BH, Shimmin LC, (Shyue SK), Hewett-Emmett D, Li WH. Weak male-driven molecular evolution in rodents. Proceedings of the National Academy of Sciences of the United States of America. 91(2), 827-31, 1994. [JCR]　[WOS]

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