Publications
Journal 61
- Hsu Hong-Ming, Huang Yu-Hsin, Aryal Sarita, Liu Hsing-Wei, Chen Chinpan, Chen Shu-Hui, Chu Chien-Hsin, Tai Jung-Hsiang. Endomembrane Protein Trafficking Regulated by a TvCyP2 Cyclophilin in the Protozoan Parasite, Trichomonas vaginalis. Scientific Reports. 10(1), 1275, 2020. [JCR] [WOS]
- Aryal Sarita, Hsu Hong-Ming, Lou Yuan-Chao, Chu Chien-Hsin, Tai Jung-Hsiang, Hsu Chun-Hua, Chen Chinpan. N-Terminal Segment of TvCyP2 Cyclophilin from Trichomonas vaginalis Is Involved in Self-Association, Membrane Interaction, and Subcellular Localization. Biomolecules. 10(9), 1239, 2020. [JCR] [WOS]
- Sadotra Sushant, Lou Yuan-Chao, Tang Hao-Cheng, Chiu Yi-Chih, Hsu Chun-Hua, Chen Chinpan. Structural basis for promoter DNA recognition by the response regulator OmpR. Journal of Structural Biology. 213(1), 107638, 2020. [JCR] [WOS]
- Lou Yuan‐Chao, Chou Chun‐Chi, Yeh Hsin‐Hong, Chien Chia‐Yu, Sadotra Sushant, Hsu Chun‐Hua, Chen Chinpan. Structural basis for −35 element recognition by σ 4 chimera proteins and their interactions with PmrA response regulator. Proteins: Structure, Function, and Bioinformatics. 88(1), 69-81, 2019. [JCR] [WOS]
- Tseng TS, Tu IF, Chen HT, Lin LC, Tsai KC, Wu SH, Chen C. Protein-DNA complex-guided discovery of the antibacterial lead E1 for restoring the susceptibility of Klebsiella Pneumoniae to polymyxin B by targeting the response regulator PmrA. CHEMICAL COMMUNICATIONS. 54(49), 6372-6375, 2018. [JCR] [WOS]
- Martin T, Lou YC, Chou CC, Wei SY, Sadotra S, Cho CC, Lin MH, Tai JH, Hsu CH, Chen C. Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis. Scientific reports. 8(1), 5410, 2018. [JCR] [WOS]
- Tseng Tien-Sheng, Tsai Keng-Chang, Chen Chinpan. Characterizing structure–function relationship reveals mode of action of a novel antimicrobial peptide, P1, from jumper ant Myrmecia pilosula. Molecular BioSystems. 13(6), 1193-1201, 2017-06. [JCR] [WOS]
- Martin T, Lou YC, Aryal S, Tai JH, Chen C. (1)H, (13)C and (15)N resonance assignments and secondary structures of cyclophilin 2 from Trichomonas vaginalis. Biomolecular NMR assignments. Sep 05, 1-4, 2017. [JCR] [WOS]
- Chou CC, Wei SY, Lou YC, Chen C. In-depth study of DNA binding of Cys2His2 finger domains in testis zinc-finger protein. PloS one. 12(4), e0175051, 2017. [JCR] [WOS]
- Tseng TS, Wang SH, Chang TW, Wei HM, Wang YJ, Tsai KC, Liao YD, Chen C. Sarkosyl-Induced Helical Structure of an Antimicrobial Peptide GW-Q6 Plays an Essential Role in the Binding of Surface Receptor OprI in Pseudomonas aeruginosa. PloS one. 11(10), e0164597, 2016. [JCR] [WOS]
- Hsu CH, Chang CF, Liao YD, Wu SH, Chen C. Solution structure and base specificity of cytotoxic RC-RNase 2 from Rana catesbeiana. Archives of biochemistry and biophysics. 584, 70-78, 2015. [JCR] [WOS]
- Lou YC, Weng TH, Li YC, Kao YF, Lin WF, Peng HL, Chou SH, Hsiao CD, Chen C. Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA. Nature communications. 6, 8838, 2015. [JCR] [WOS]
- Lou YC, Wang I, Rajasekaran M, Kao YF, Ho MR, Hsu ST, Chou SH, Wu SH, Chen C. Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae. Nucleic acids research. 42(6), 4080-4093, 2014-04. [JCR] [WOS]
- Lou YC, Kao YF, Chin KH, Chen JK, Tu JL, Chen C, Chou SH. Backbone resonance assignments of the 54 kDa dimeric C-terminal domain of murine STING in complex with DMXAA. Biomolecular NMR Assignments. 9(2), 271-274, 2014. [JCR] [WOS]
- Hsu HM, Chu CH, Wang YT, Lee Y, Wei SY, Liu HW, Ong SJ, Chen C, Tai JH. Regulation of nuclear translocation of the Myb1 transcription factor by TvCyclophilin 1 in the protozoan parasite Trichomonas vaginalis. The Journal of biological chemistry. 289(27), 19120-19136, 2014. [JCR] [WOS]
- Chin KH, Tu ZL, Su YC, Yu YJ, Chen HC, Lo YC, Chen CP, Barber GN, Chuah ML, Liang ZX, Chou SH. Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING. Acta Crystallographica Section D-Biological Crystallography. 69(Pt 3), 352-366, 2013. [JCR] [WOS]
- Luo SC, Lou YC, Rajasekaran M, Chang YW, Hsiao CD, Chen C. Structural basis of a physical blockage mechanism for the interaction of response regulator PmrA with connector protein PmrD from Klebsiella pneumoniae. The Journal of biological chemistry. 288(35), 25551-25561, 2013. [JCR] [WOS]
- Ho MR, Chen C. 1H, 13C, and 15N resonance assignments for human regenerating family Ialpha protein. Biomolecular NMR assignments. 6(2), 135-137, 2012. [JCR] [WOS]
- Hsu HM, Lee Y, Indra D, Wei SY, Liu HW, Chang LC, Chen C, Ong SJ, Tai JH. Iron-Inducible Nuclear Translocation of a Myb3 Transcription Factor in the Protozoan Parasite Trichomonas vaginalis. Eukaryotic cell. 11(12), 1441-1450, 2012. [JCR] [WOS]
- Kao YF, Lou YC, Yeh YH, Hsiao CD, Chen C. Solution structure of the C-terminal NP-repeat domain of Tic40, a co-chaperone during protein import into chloroplasts. Journal of biochemistry. 152(5), 443-51, 2012. [JCR] [WOS]
- Rajasekaran M, Chen C. Structural effect of the L16Q, K50E, and R53P mutations on homeodomain of pituitary homeobox protein 2. International journal of biological macromolecules. 51(3), 305-13, 2012. [JCR] [WOS]
- Wei SY, Lou YC, Tsai JY, Ho MR, Chou CC, Rajasekaran M, Hsu HM, Tai JH, Hsiao CD, Chen C. Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal beta-hairpin conformation. Nucleic acids research. 40(1), 449-60, 2012. [JCR] [WOS]
- Chu CH, Chang LC, Hsu HM, Wei SY, Liu HW, Lee Y, Kuo CC, Indra D, Chen C, Ong SJ, Tai JH. A highly organized structure mediating nuclear localization of a Myb2 transcription factor in the protozoan parasite Trichomonas vaginalis. Eukaryotic cell. 10(12), 1607-1617, 2011. [JCR] [WOS]
- Rajasekaran M, Abirami S, Chen C. Effects of single nucleotide polymorphisms on human N-acetyltransferase 2 structure and dynamics by molecular dynamics simulation. PloS one. 6(9), e25801, 2011. [JCR] [WOS]
- Pan, Y. R., Lou, Y. C., Seven, A. B., Rizo, J. and Chen, C.*. NMR Structure and Calcium-Binding Properties of the Tellurite Resistance Protein TerD from Klebsiella pneumonia. J. Mol. Biol.. 405(5), 1188-1201, 2010-11. [JCR] [WOS]
- Ho, M. R., Lou, Y. C., Wei, S. Y., Luo, S. C., Lin, W. C., Lyu, P. C. and Chen, C.*. Human RegIV Protein Adopts a C-Type Lectin Fold but Binds Mannan with Two Calcium-Independent Sites. JOURNAL OF MOLECULAR BIOLOGY. 402, 682-695, 2010-10. [JCR] [WOS]
- Luo, S. C., Lou, Y. C., Cheng, H. Y., Pan, Y. R., Peng, H. L. and Chen, C.*. Solution structure and phospho-PmrA recognition mode of PmrD from Klebsiella pneumoniae. JOURNAL OF STRUCTURAL BIOLOGY. 172, 319-330, 2010-10. [JCR] [WOS]
- Hsu, C. H., Pan, Y. R., Liao, Y. D., Wu, S. H. and Chen, C.*. NMR and biophysical elucidation of structural effects on extra N-terminal methionine residue of recombinant amphibian RNases from Rana catesbeiana. JOURNAL OF BIOCHEMISTRY. 148, 209-215, 2010-08. [JCR] [WOS]
- Chou, C. C., Lou, Y. C., Tang, T. K. and Chen, C.*. Structure and DNA binding characteristics of the three-Cys2His2 domain of mouse testis zinc finger protein. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 78, 2202-2212, 2010-08. [JCR] [WOS]
- Chou, C. C., Rajasekaran, M. and Chen, C.*. An effect approach for generating a three-Cys2His2 zinc-finger-DNA complex model by docking. BMC Bioinformatics. 11, 334, 2010-06. [JCR] [WOS]
- Elumalai, P., Rajasekaran, M. Liu, H. L. and Chen, C. Investigation of cation-π interactions in sugar-binding proteins. PROTOPLASMA. 247(1-2), 13-24, 2010-04. [JCR] [WOS]
- Lin, Y. C., Lee, H. C., Wang, I., Hsu, C. H., Liao, J. H., Lee, A. Y. L., Chen, C and Wu, S. H. DNA-binding specificity of the Lon protease α-domain from Brevibacillus thermoruber WR-249. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 388, 62-66, 2009-10. [JCR] [WOS]
- Hwang, H.W., Lee, J.R., Chou, K.Y., Suen, C.S., Hwang, M.J., Chen, C., Shieh, R.C. and Chau, L.Y. Oligomerization is crucial for the stability and function of heme oxygenase-1 in the endoplasmic reticulum. J. Biol. Chem.. 284, 22672-22679, 2009-06. [JCR] [WOS]
- Lou, Y.C., Wei, S.Y., Rajasekaran, M., Chou, C.C., Hsu, H.M., Tai, J.H. and Chen, C. NMR structural analysis of DNA recognition by a novel Myb1 DNA binding domain in the protozoan parasite Trichomonas vaginalis. Nucleic Acids Research. 37(7), 2381-2394, 2009-04. [JCR] [WOS]
- 45. Hwang, H.W., Lee, J.R., Chou, K.Y., Suen, C.S., Hwang, M.J., Chen, C., Shieh, R.C. and Chau, L.Y. Oligomerization is crucial for the stability and function of heme oxygenase-1 in the endoplasmic reticulum. J. Biol. Chem.. 284, 22672-22679, 2009. [JCR] [WOS]
- Huang, S.Y., Wen, C.H., Li, D.T., Hsu, J.L., Chen, C., Shi, F.K. and Lin, Y.Y. . Assignment of disulfide-linked peptides using automatic a1 ion recognition. Analytical chemistry. 80(23), 9135-9140, 2008-11. [JCR] [WOS]
- S. K. Chiang, Y. C. Lou and C. Chen. NMR solution structure of KP-TerB, a tellurite-resistance protein from Klebsiella pneumoniae. Protein Sci. 17(4), 785-789, 2008. [JCR] [WOS]
- Wang, Y. C. Lou, Y. C. Lin, S. C. Lo, A. Y. L. Lee, S. H. Wu and C. Chen. 1H, 13C and 15N resonance assignments of alpha-domain for Bacillus subtilis Lon protease. Biomol NMR Assign. 1, 201-203, 2007. [JCR] [WOS]
- Y. C. Huang, Y. M. Lin, T. W. Chang, S. J. Wu, Y. S. Lee, M. D. Chang, C. Chen, S. H. Wu and Y. D. Liao. The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity. J Biol Chem. 282(7), 4626-4633, 2007. [JCR] [WOS]
- M. R. Ho, Y. C. Lou, W. C. Lin, P. C. Lyu, W. N. Huang and C. Chen. Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation. J Biol Chem. 281(44), 33566-33576, 2006. [JCR] [WOS]
- K. T. Huang, B. C. Wu, C. C. Lin, S. C. Luo, C. Chen, C. H. Wong and C. C. Lin. Multi-enzyme one-pot strategy for the synthesis of sialyl Lewis X-containing PSGL-1 glycopeptide. CARBOHYDRATE RESEARCH. 341, 2151-2155, 2006. [JCR] [WOS]
- Y. C. Lou, Y. C. Huang, Y. R. Pan, C. Chen and Y. D. Liao. Roles of N-terminal pyroglutamate in maintaining structural integrity and pKa values of catalytic histidine residues in bullfrog ribonuclease 3. J Mol Biol. 355, 409-421, 2006. [JCR] [WOS]
- Y. R. Pan, K. P. Wu, Y. C. Lou, Y. D. Liao and C. Chen. 1H, 13C and 15N resonance assignments and secondary structure of murine angiogenin 4. J Biomol NMR. 31, 175-176, 2005. [JCR] [WOS]
- I. Wang, Y. C. Lou, K. P. Wu, S. H. Wu, W. C. Chang and C. Chen. Novel solution structure of porcine beta-microseminoprotein. J Mol Biol. 346, 1071-1082, 2005. [JCR] [WOS]
- C. H. Hsu, C. Chen, M. L. Jou, A. Y. L. Lee, Y. C. Lin, Y. P. Yu, W. T. Huang and S. H. Wu. Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA. Nucleic Acids Res. 33, 4053-4064, 2005. [JCR] [WOS]
- M. R. Ho, Y. C. Lou, W. C. Lin, P. C. Lyu and C. Chen. (1)H, (13)C, and (15)N resonance assignments and secondary structure of human pancreatitis-associated protein (hPAP). J Biomol NMR. 30, 381-382, 2004. [JCR] [WOS]
- Y. R. Pan, K. P. Wu, Y. C. Lou, Y. D. Liao and C. Chen. Letter to the Editor: 1H, 13C and 15N resonance assignments and secondary structure of the cytotoxic RNase 3 from oocytes of bullfrog Rana catesbeiana. J Biomol NMR. 27, 289-290, 2004. [JCR] [WOS]
- Wang, T. A. Yu, S. H. Wu, W. C. Chang and C. Chen. Disulfide pairings and secondary structure of porcine beta-microseminoprotein. FEBS Lett. 541, 80-84, 2003. [JCR] [WOS]
- C. H. Hsu, Y. D. Liao, Y. R. Pan, L. W. Chen, S. H. Wu, Y. J. Leu and C. Chen. Solution structure of the cytotoxic RNase 4 from oocytes of bullfrog Rana catesbeiana. J Mol Biol. 326, 1189-1201, 2003. [JCR] [WOS]
- Y. D. Liao, S. C. Wang, Y. J. Leu, C. F. Wang, S. T. Chang, Y. T. Hong, Y. R. Pan and C. Chen. The structural integrity exerted by N-terminal pyroglutamate is crucial for the cytotoxicity of frog ribonuclease from Rana pipiens. Nucleic Acids Res. 31, 5247-5255, 2003. [JCR] [WOS]
- Y. J. Sun, F. Forouhar, H. M. Li Hm, S. L. Tu, Y. H. Yeh, S. Kao, H. L. Shr, C. C. Chou, C. Chen and C. D. Hsiao. Crystal structure of pea Toc34, a novel GTPase of the chloroplast protein translocon. Nature Structural Biology. 9(2), 95-100, 2002. [JCR] [WOS]
- F. D. Lung, J. Y. Tsai, S. Y. Wei, J. W. Cheng, C. Chen, P. Li and P. P. Roller. Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance. J Pept Res. 60, 143-149, 2002. [JCR] [WOS]
- Wang, S. H. Wu, H. K. Chang, R. C. Shieh, H. M. Yu and C. Chen. Solution structure of a K(+)-channel blocker from the scorpion Tityus cambridgei. Protein Sci. 11(2), 390-400, 2002. [JCR] [WOS]
- C. H. Hsu, S. H. Wu, D. K. Chang and C. Chen. Structural characterizations of fusion peptide analogs of influenza virus hemagglutinin. Implication of the necessity of a helix-hinge-helix motif in fusion activity. J Biol Chem. 277, 22725-22733, 2002. [JCR] [WOS]
- N. Y. Su, Y. D. Liao, C. F. Chang, I. Wang and C. Chen. Letter to the Editor: 1H, 15N and 13C resonance assignments and secondary structure of the liver ribonuclease from bullfrog Rana catesbeiana. J. Biomol. NMR. 20, 189-190, 2001. [JCR] [WOS]
- C. H. Hsu, Y. D. Liao, S. H. Wu and C. Chen. Letter to the Editor:1H, 13C and 15N resonance assignments and secondary structure of the cytotoxic protein RNase 4 from bullfrog Rana catesbeiana oocytes. J Biomol NMR. 20, 93-94, 2001. [JCR] [WOS]
- C. H. Hsu, L. W. Chen, Y. D. Liao, S. H. Wu and C. Chen. Letter to the Editor:1H, 15N and 13C resonance assignments and secondary structure determination of the RC-RNase 2 from oocytes of bullfrog Rana catesbeiana. J Biomol NMR. 19, 87-88, 2001. [JCR] [WOS]
- C. Chen, C. H. Hsu, N. Y. Su, Y. C. Lin, S. H. Chiou and S. H. Wu. Solution structure of a Kunitz-type chymotrypsin inhibitor isolated from the elapid snake Bungarus fasciatus. J Biol Chem. 276, 45079-45087, 2001. [JCR] [WOS]
- A. I. Arunkumar, S. Srisailam, T. K. Kumar, K. M. Kathir, C. L. Peng, C. Chen, I. M. Chiu and C. Yu. Letter to the editor: 1H, 13C and 15N chemical shift assignments of the acidic fibroblast growth factor from Notopthalmus viridescens. J Biomol NMR. 17, 279-280, 2000. [JCR] [WOS]
- T. H. Lin, C. Chen, R. F. Huang, Y. L. Lee, J. F. Shaw and T. H. Huang. Multinuclear NMR resonance assignments and the secondary structure of Escherichia coli thioesterase/protease I: a member of a new subclass of lipolytic enzymes. J Biomol NMR. 11, 363-380, 1998. [JCR] [WOS]
- C. F. Chang, C. Chen, Y. C. Chen, K. Hom, R. F. Huang and T. H. Huang. The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana (bullfrog). J Mol Biol. 283, 231-244, 1998. [JCR] [WOS]