中央研究院生命科學圖書館 -- 生命組研究成果

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生命組研究成果

生物醫學科學研究所 - 柯泰名 Ko, Tai-Ming

期刊 32

Chen PY, (Ko TM)*. OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells. Advanced Intelligent Systems. 2400321, 1-11, 2024-08-04. [JCR]　[WOS]
Siew JJ, Chen HM, Chiu FL, Lee CW, Chang YM, Chen HL, Nguyen TNA, Liao HT, Liu M, Hagar HT, Sun YC, Lai HL, Kuo MH, Blum D, Buée L, Jin LW, Chen SY, (Ko TM), Huang JR, Kuo HC, Liu FT, Chern Y. Galectin-3 aggravates microglial activation and tau transmission in tauopathy. Journal of Clinical Investigation. 134(2), e165523, 2024-01-16. [JCR]　[WOS]
Toh SI, Elaine Keisha J, Wang YL, Pan YC, Jhu YH, Hsiao PY, Liao WT, Chen PY, (Ko TM), Chang CY. Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin. Communications biology. 6(1), 1282, 2023-12-19. [JCR]　[WOS]
Beltran JVB, Lin FP, Chang CL, (Ko TM)*. Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers. Circulation. 148(22), 1778-1796, 2023-11-28. [JCR]　[WOS]
Wei KH, Lin IT, Chowdhury K, Lim KL, Liu KT, (Ko TM), Chang YM, Yang KC, Lai SB. Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration. eLife. 12, e84679, 2023-07-27. [JCR]　[WOS]
Chen IC, Chen HH, Jiang YH, Hsiao TH, (Ko TM), Chao WC. Whole transcriptome analysis to explore the impaired immunological features in critically ill elderly patients with sepsis. Journal of Translational Medicine. 21(1), 141, 2023-02-23. [JCR]　[WOS]
Chung WS, Chen SC, (Ko TM), Lin YC, Lin SH, Lo YF, Tseng SC, Yu CC*. An Integrative Clinical Model for the Prediction of Pathological Complete Response in Patients with Operable Stage II and Stage III Triple-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy. Cancers. 14(17), 4170, 2022-08-28. [JCR]　[WOS]
Kuo CL, Chou HY, Lien HW, Yeh CA, Wang JR, Chen CH, Fan CC, Hsu CP, Kao TY, (Ko TM), Lee AY*. A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment. Cancer Immunology, Immunotherapy. 72(2), 351-369, 2022-07-27. [JCR]　[WOS]
Chao WC#, Liao WT#, Wang JR, Sung HN, Chen HH, Lin FP, Huang JY, Liu KT, (Ko TM)*. Single‐cell profiling reveals novel cellular heterogeneity of monocytes during Hymenoptera venom allergy. Clinical and Translational Allergy. 12(5), e12151, 2022-05-05. [JCR]　[WOS]
Kao CM, Wang JS, Ho WL, (Ko TM), Chen HM, Lin CH, Huang WN, Chen YH, Chen HH*. Factors Associated with the Risk of Major Adverse Cardiovascular Events in Patients with Ankylosing Spondylitis: A Nationwide, Population-Based Case-Control Study. International journal of environmental research and public health. 19(7), 4098, 2022-03-30. [JCR]　[WOS]
Huang LW, Wei JC, Chen DY, Chen YJ, Tang KT, Ko TM, Chen HH. Bidirectional association between systemic lupus erythematosus and macrophage activation syndrome: a nationwide population-based study. Rheumatology (Oxford, England). 61(3), 1123-1132, 2022. [JCR]　[WOS]
Cheng PL, Chen HH, Jiang YH, Hsiao TH, Wang CY, Wu CL, (Ko TM), Chao WC*. Using RNA-Seq to Investigate Immune-Metabolism Features in Immunocompromised Patients With Sepsis. Frontiers in Medicine. 8, 747263, 2021-12-17. [JCR]　[WOS]
Sun TH, Mao LC, Hung MN, Lo YY, (Ko TM), Shao YH, Hsiao TH*. A Novel Quality-Control Procedure to Improve the Accuracy of Rare Variant Calling in SNP Arrays. Frontiers in Genetics. 12, 736390, 2021-10-26. [JCR]　[WOS]
Sun CP, Jan JT, Wang IH, Ma HH, Ko HY, Wu PY, Kuo TJ, Liao HN, Lan YH, Sie ZL, Chen YH, Ko YA, Liao CC, Chen LY, Lee IJ, Tsung SI, Lai YJ, Chiang MT, Liang JJ, Liu WC, Wang JR, Yuan JP, Lin YS, Tsai YC, Hsieh SL, Li CW, Wu HC, (Ko TM), Lin YL*, Tao MH*. Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19. PLOS Pathogens. 17(8), e1009758, 2021-08-11. [JCR]　[WOS]
Shih YC, Chen PY, (Ko TM), Huang PH, Ma H, Tarng DC*. MMP-9 Deletion Attenuates Arteriovenous Fistula Neointima through Reduced Perioperative Vascular Inflammation. International Journal of Molecular Sciences. 22(11), 5448, 2021-05-21. [JCR]　[WOS]
Chang CL, Lin MC, Lin CH, Ko TM. Maternal and Perinatal Factors Associated With Kawasaki Disease Among Offspring in Taiwan. JAMA network open. 4(3), e213233, 2021. [JCR]　[WOS]
Huang WC, Huang HT, Chen PY, Wang WC, Ko TM, Shrestha S, Yang CD, Tai CS, Chiew MY, Chou YP, Hu YF, Huang HD. SVAD: A genetic database curates non-ischemic sudden cardiac death-associated variants. PloS one. 15(8), e0237731, 2020. [JCR]　[WOS]
Ko TM, Chang JS, Chen SP, Liu YM, Chang CJ, Tsai FJ, Lee YC, Chen CH, Chen YT, Wu JY. Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease. Scientific reports. 9(1), 328, 2019. [JCR]　[WOS]
Ko TM, Kiyotani K, Chang JS, Park JH, Yin Yew P, Chen YT, Wu JY, Nakamura Y. Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment. Human molecular genetics. 27(15), 2671-2677, 2018. [JCR]　[WOS]
Lee TH, Ko TM, Chen CH, Chang YJ, Lu LS, Chang CH, Huang KL, Chang TY, Lee JD, Chang KC, Yang JT, Wen MS, Wang CY, Chen YT, Chen TC, Chou SY, Lee MM, Chen YT, Wu JY. A genome-wide association study links small-vessel ischemic stroke to autophagy. Scientific reports. 7(1), 15229, 2017. [JCR]　[WOS]
Lee TH, Ko TM, Chen CH, Lee MT, Chang YJ, Chang CH, Huang KL, Chang TY, Lee JD, Chang KC, Yang JT, Wen MS, Wang CY, Chen YT, Hsieh CS, Chou SY, Liu YM, Chen HW, Liao HT, Wang CW, Chen SP, Lu LS, Chen YT, Wu JY. Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study. Journal of the American Heart Association. 5(3), e003003, 2016. [JCR]　[WOS]
Ko TM, Wong CS, Wu JY, Chen YT. Pharmacogenomics for personalized pain medicine. Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists. 54(1), 24-30, 2016. [JCR]
Ko TM, Kuo HC, Chang JS, Chen SP, Liu YM, Chen HW, Tsai FJ, Lee YC, Chen CH, Wu JY, Chen YT. CXCL10/IP-10 is a biomarker and mediator for Kawasaki disease. Circulation research. 116(5), 876-83, 2015. [JCR]　[WOS]
Lin CH, Chen JK, Ko TM, Wei CY, Wu JY, Chung WH, Chen SY, Liao YD, Hung SI, Chen YT. Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction. The Journal of allergy and clinical immunology. 135(4), 1063-1065.e5, 2015. [JCR]　[WOS]
Ko TM, Tsai CY, Chen SY, Chen KS, Yu KH, Chu CS, Huang CM, Wang CR, Weng CT, Yu CL, Hsieh SC, Tsai JC, Lai WT, Tsai WC, Yin GD, Ou TT, Cheng KH, Yen JH, Liou TL, Lin TH, Chen DY, Hsiao PJ, Weng MY, Chen YM, Chen CH, Liu MF, Yen HW, Lee JJ, Kuo MC, Wu CC, Hung SY, Luo SF, Yang YH, Chuang HP, Chou YC, Liao HT, Wang CW, Huang CL, Chang CS, Lee MT, Chen P, Wong CS, Chen CH, Wu JY, Chen YT, Shen CY. Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study. BMJ (Clinical research ed.). 351, h4848, 2015. [JCR]　[WOS]
Chang CJ, Kuo HC, Chang JS, Lee JK, Tsai FJ, Khor CC, Chang LC, Chen SP, Ko TM, Liu YM, Chen YJ, Hong YM, Jang GY, Hibberd ML, Kuijpers T, Burgner D, Levin M, Burns JC, Davila S, Chen YT, Chen CH, Wu JY, Lee YC. Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility. PloS one. 8(8), e72037, 2013. [JCR]　[WOS]
Wei CY, Ko TM, Shen CY, Chen YT. A recent update of pharmacogenomics in drug-induced severe skin reactions. Drug metabolism and pharmacokinetics. 27(1), 132-141, 2012. [JCR]　[WOS]
Ko TM, Chen YT. T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction. Expert review of clinical immunology. 8(5), 467-77, 2012. [JCR]　[WOS]
Ko TM, Chung WH, Wei CY, Shih HY, Chen JK, Lin CH, Chen YT, Hung SI. Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome. The Journal of allergy and clinical immunology. 128(6), 1266-1276.e11, 2011. [JCR]　[WOS]
Tu CF, Lin CC, Chen MC, Ko TM, Lin CM, Wang YC, Lai MD. Autologous neu DNA vaccine can be as effective as xenogenic neu DNA vaccine by altering administration route. Vaccine. 25(4), 719-728, 2007. [JCR]　[WOS]
Chen CC, (Ko TM), Ma HI, Wu HL, Xiao X, Li J, Chang CM, Wu PY, Chen CH, Han JM, Yu CP, Jeng KS, Hu CP, Tao MH. Long-term inhibition of hepatitis B virus in transgenic mice by double-stranded adeno-associated virus 8-delivered short hairpin RNA. Gene Therapy. 14(1), 11-19, 2006-08-24. [JCR]　[WOS]
Lin CC, Chou CW, Shiau AL, Tu CF, Ko TM, Chen YL, Yang BC, Tao MH, Lai MD. Therapeutic HER2/Neu DNA vaccine inhibits mouse tumor naturally overexpressing endogenous neu. Molecular therapy : the journal of the American Society of Gene Therapy. 10(2), 290-301, 2004. [JCR]　[WOS]

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