生命組研究成果
期刊 38
- Binay K. Sahoo, Yuh-Charn Lin, Cheng-Fen Tu, Chien-Chin Lin, Wei-Ju Liao, Fu-An Li, (Ling-Hui Li), Yun Mou, Steve R. Roffler, Shu-Ping Wang, Chi-Tai Yeh, Chi-Yuan Yao, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Ruey-Bing Yang*. Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia. Haematologica. 108, 5, 2023-05. [JCR] [WOS]
- Chia-Hui Lo, Deng-Chyang Wu, Shu-Wen Jao, Chang-Chieh Wu, Chung-Yen Lin, Chia-Hsien Chuang, Ya-Bo Lin, Chien-Hsiun Chen, Ying-Ting Chen, Jiann-Hwa Chen, Koung-Hung Hsiao, Ying-Ju Chen, Yuan-Tsong Chen, Jaw-Yuan Wang*, (Ling-Hui Li)*. Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas. JOURNAL OF BIOMEDICAL SCIENCE. 29, 88, 2022-10-27. [JCR] [WOS]
- Cheng-Fen Tu, Fu-An Li, (Ling-Hui Li) and Ruey-Bing Yang*. Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness. BREAST CANCER RESEARCH. 24, 21, 2022-03. [JCR] [WOS]
- Wei Chun-Yu, Yang Jenn-Hwai, Yeh Erh-Chan, Tsai Ming-Fang, Kao Hsiao-Jung, Lo Chen-Zen, Chang Lung-Pao, Lin Wan-Jia, Hsieh Feng-Jen, Belsare Saurabh, Bhaskar Anand, Su Ming-Wei, Lee Te-Chang, Lin Yi-Ling, Liu Fu-Tong, Shen Chen-Yang, (Li Ling-Hui), Chen Chien-Hsiun, Wall Jeffrey D., Wu Jer-Yuarn, Kwok Pui-Yan*. Genetic profiles of 103,106 individuals in the Taiwan Biobank provide insights into the health and history of Han Chinese. npj Genomic Medicine. 6(1), 10, 2021-02. [JCR] [WOS]
- Chen Yen-Cheng, Miao Zhi-Feng, Yip Kwan-Ling, Cheng Yi-An, Liu Chung-Jung, (Li Ling-Hui), Lin Chung-Yen, Wang Jiunn-Wei, Wu Deng-Chyang, Cheng Tian-Lu, Wang Jaw-Yuan*. Gut Fecal Microbiota Transplant in a Mouse Model of Orthotopic Rectal Cancer. Frontiers in Oncology. 10, 568012, 2020-10. [JCR] [WOS]
- Huang Ching-Ying, (Li Ling-Hui), Hsu Wan-Tseng, Cheng Yu-Che, Nicholson Martin W., Liu Chun-Lin, Ting Chien-Yu, Ko Hui-Wen, Syu Shih-Han, Wen Cheng-Hao, Yan Zhuge, Huang Hsiang-Po, Su Hong-Lin, Chiang Po-Min, Shen Chia-Ning, Chen Hsin-Fu, Yen B. Lin Ju, Lu Huai-En, Hwang Shiaw-Min, Chiou Shih-Hwa, Ho Hong-Nerng, Wu Jer-Yuarn, Kamp Timothy J., Wu Joseph C., Hsieh Patrick C. H.*. Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank. Journal of Biomedical Science. 27(1), 92, 2020-09. [JCR] [WOS]
- Shen Wen-Ching, Lai Yung-Chih, (Li Ling-Hui), Liao Kolin, Lai Hung-Chang, Kao Shou-Yen, Wang John, Chuong Cheng-Ming, Hung Shih-Chieh*. Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis. Nature Communications. 10(1), 2226, 2019-05. [JCR] [WOS]
- Chen CH, Chen HI, Chien WH, (Li LH), Wu YY, Chiu YN, Tsai WC, Gau SS*. High resolution analysis of rare copy number variants in patients with autism spectrum disorder from Taiwan. Scientific reports. 7(1), 11919, 2017-09. [JCR] [WOS]
- Chuang, T.P., Wang, J.Y., Jao, S.W., Wu, C.C., Chen, J.H., Hsiao, K.H., Lin, C.Y., Chen, S.H., Su, S.Y., Chen, Y.J., Chen, Y.T., Wu, D.C.*, (Li, L.H.)*. Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression. Oncotarget. 7(29), 45803-45818, 2016-06. [JCR] [WOS]
- Lin, Y.-F., (Li, L.-H.), Lin, C.-H., Tsou, M.-H., Chuang, M.-T.K., Wu, K.-M., Liao, T.-L., Li, J.-C., Wang, W.-J., Tomita, A., Tomita, B., Huang, S.-F., Tsai, S.-F.*. Selective Retention of an Inactive Allele of the DKK2 Tumor Suppressor Gene in Hepatocellular Carcinoma. PLoS Genetics. 12, e1006051, 2016-05. [JCR] [WOS]
- Huang, M.-C., Chuang, T.-P., Chen, C.-H., Wu, J.-Y., Chen, Y.-T., (Li, L.-H.)*, Yang, H.-C*. An integrated analysis tool for analyzing hybridization intensities and genotypes using new-generation population-optimized human arrays. BMC GENOMICS. 17, 266, 2016-03. [JCR] [WOS]
- Yin, C.-L., Chen, H.-I., (Li, L.-H.), Chien, Y.-L., Liao, H.-M., Chou, M.C., Chou, W.-J., Tsai, W.-C., Chiu, Y.-N., Wu, Y.-Y., Lo, C.-Z., Wu, J.-Y., Chen, Y.-T., Gau, S.S.-F.* (co-first author). Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder. Molecular Autism. 7, 23, 2016-03. [JCR] [WOS]
- Lin DS, Chuang TP, Chiang MF, Ho CS, Hsiao CD, Huang YW, Wu TY, Wu JY, Chen YT, Chen TC, (Li LH*). De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay. Gene. 533, 78-85, 2014. [JCR] [WOS]
- Chiu LY, Kishnani PS, Chuang TP, Tang CY, Liu CY, Bali D, Koeberl D, Austin S, Boyette K, Weinstein DA, Murphy E, Yao A, Chen YT, (Li LH*). Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers. Journal of gastroenterology. 49, 1274-1284, 2014. [JCR] [WOS]
- Lin YC, Lee YC, (Li LH), Cheng CJ, Yang RB*. Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition. Journal of cell science. 127, 85-100, 2014. [JCR] [WOS]
- Lin CH, Lin JK, Chang SC, Chang YH, Chang HM, Liu JH, (Li LH), Chen YT, Tsai SF, Chen WS. Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan. Journal of biomedical science. 18, 36, 2011. [JCR] [WOS]
- Yang HC, Lin HC, Kang M, Chen CH, Lin CW, Li LH, Wu JY, Chen YT, Pan WH. SAQC: SNP array quality control. BMC bioinformatics. 12, 100, 2011. [JCR] [WOS]
- Yang HC, Lin HC, Huang MC, Li LH, Pan WH, Wu JY, Chen YT. A new analysis tool for individual-level allele frequency for genomic studies. BMC genomics. 11, 415, 2010. [JCR] [WOS]
- Chien SC, Li YC, Li LH, Wu JY, Hsu PC, Shi SL, Tsai FJ, Lin CC. A new familial insertion, ins(18;9)(q12.2;q33.1q31.1) with a 9q31.1-9q33.1 deletion in a girl with a cleft lip and palate. American Journal of Medical Genetics Part A. 152A(7), 1862-1867, 2010. [JCR] [WOS]
- Shiao YM, Lee CC, Hsu YH, Huang SF, Lin CY, Li LH, Fann CS, Tsai CY, Tsai SF, Chiu HC. Ectopic and high CXCL13 chemokine expression in myasthenia gravis with thymic lymphoid hyperplasia. Journal of neuroimmunology. 221(1-2), 101-106, 2010. [JCR] [WOS]
- Chang CF, Li LH, Wang CH, Tsai FJ, Chen TC, Wu JY, Chen YT, Tsai AC. Identification of a submicroscopic 3.2 Mb chromosomal 16q12.2-13 deletion in a child with short stature, mild developmental delay, and craniofacial anomalies, by high-density oligonucleotide array-a recognizable syndrome. American Journal of Medical Genetics Part A. 152A(9), 2365-2371, 2010. [JCR] [WOS]
- Chen YK, Chang WS, Wu IC, Li LH, Yang SF, Chen JY, Hsu MC, Chen SH, Wu DC, Lee JM, Huang CH, Goan YG, Chou SH, Huang CT, Wu MT. Molecular characterization of invasive subpopulations from an esophageal squamous cell carcinoma cell line. Anticancer research. 30(3), 727-736, 2010. [JCR] [WOS]
- Wu IC, Wu DC, Huang CC, Lin HS, Chen YK, Tsai HJ, Lu CY, Chou SH, Chou YP, Li LH, Tai SY, Wu MT. Plasma decorin predicts the presence of esophageal squamous cell carcinoma. International journal of cancer. 127(9), 2138-2146, 2010. [JCR] [WOS]
- Kishnani PS, Chuang TP, Bali D, Koeberl D, Austin S, Weinstein DA, Murphy E, Chen YT, Boyette K, Liu CH, Chen YT, Li LH. Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease. Human molecular genetics. 18(24), 4781-4790, 2009. [JCR] [WOS]
- Wu KM, Li LH, Yan JJ, Tsao N, Liao TL, Tsai HC, Fung CP, Chen HJ, Liu YM, Wang JT, Fang CT, Chang SC, Shu HY, Liu TT, Chen YT, Shiau YR, Lauderdale TL, Su IJ, Kirby R, Tsai SF. Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis. Journal of bacteriology. 191(14), 4492-4501, 2009. [JCR] [WOS]
- Lin CH, Li LH, Ho SF, Chuang TP, Wu JY, Chen YT, Fann CS. A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan. BMC genetics. 9, 92, 2008. [JCR] [WOS]
- Lin CH, Huang MC, Li LH, Wu JY, Chen YT, Fann CS. Genome-wide copy number analysis using copy number inferring tool (CNIT) and DNA pooling. Human mutation. 29(8), 1055-1062, 2008. [JCR] [WOS]
- Yang HC, Huang MC, Li LH, Lin CH, Yu AL, Diccianni MB, Wu JY, Chen YT, Fann CS. MPDA: microarray pooled DNA analyzer. BMC bioinformatics. 9, 196, 2008. [JCR] [WOS]
- Huggins R, Li LH, Lin YC, Yu AL, Yang HC. Nonparametric estimation of LOH using Affymetrix SNP genotyping arrays for unpaired samples. Journal of human genetics. 53(11-12), 983-990, 2008. [JCR] [WOS]
- Yang HC, Liang YJ, Huang MC, Li LH, Lin CH, Wu JY, Chen YT, Fann CS. A genome-wide study of preferential amplification/hybridization in microarray-based pooled DNA experiments. Nucleic acids research. 34(15), e106, 2006. [JCR] [WOS]
- Chen YT, Shu HY, Li LH, Liao TL, Wu KM, Shiau YR, Yan JJ, Su IJ, Tsai SF, Lauderdale TL. Complete nucleotide sequence of pK245, a 98-kilobase plasmid conferring quinolone resistance and extended-spectrum-beta-lactamase activity in a clinical Klebsiella pneumoniae isolate. Antimicrobial agents and chemotherapy. 50(11), 3861-3866, 2006. [JCR] [WOS]
- Li LH, Ho SF, Chen CH, Wei CY, Wong WC, Li LY, Hung SI, Chung WH, Pan WH, Lee MT, Tsai FJ, Chang CF, Wu JY, Chen YT. Long contiguous stretches of homozygosity in the human genome. Human mutation. 27(11), 1115-1121, 2006. [JCR] [WOS]
- Jong YJ, Li LH, Tsou MH, Chen YJ, Cheng SH, Wang-Wuu S, Tsai SF, Chen CM, Huang AT, Hsu MT, Lin CH. Chromosomal comparative genomic hybridization abnormalities in early- and late-onset human breast cancers: correlation with disease progression and TP53 mutations. Cancer genetics and cytogenetics. 148(1), 55-65, 2004. [JCR] [WOS]
- Chang YT, Shiao YM, Chin PJ, Liu YL, Chou FC, Wu S, Lin YF, Li LH, Lin MW, Liu HN, Tsai SF. Genetic polymorphisms of the HCR gene and a genomic segment in close proximity to HLA-C are associated with patients with psoriasis in Taiwan. The British journal of dermatology. 150(6), 1104-1111, 2004. [JCR] [WOS]
- Vander Zwan CJ, Wheeler JC, Li LH, Tracey WD, Gergen JP. A DNA-binding-independent pathway of repression by the Drosophila Runt protein. Blood Cells Molecules and Diseases. 30(2), 207-222, 2003. [JCR] [WOS]
- Li LH, Gergen JP. Differential interactions between Brother proteins and Runt domain proteins in the Drosophila embryo and eye. Development. 126(15), 3313-3222, 1999. [JCR] [WOS]
- Aimes RT, Li LH, Weaver B, Hawkes S, Hahn-Dantona EA, Quigley JP. Cloning, expression, and characterization of chicken tissue inhibitor of metalloproteinase-2 (TIMP-2) in normal and transformed chicken embryo fibroblasts. Journal of cellular physiology. 174(3), 342-352, 1998. [JCR] [WOS]
- Golling G, Li L, Pepling M, Stebbins M, Gergen JP. Drosophila homologs of the proto-oncogene product PEBP2/CBF beta regulate the DNA-binding properties of Runt. Molecular and cellular biology. 16(3), 932-942, 1996. [JCR] [WOS]