中央研究院生命科學圖書館 -- 生命組研究成果

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生命組研究成果

生物醫學科學研究所 - 黃怡萱 Huang, Yi-Shuian

期刊 67

Chao YW, Lee YL, Tseng CS, Wang LU, Hsia KC, Chen H, Fustin JM, Azeem S, Chang TT, Chen CY, Kung FC, Hsueh YP*, (Huang YS)*, Chao HW*. Improved CaP Nanoparticles for Nucleic Acid and Protein Delivery to Neural Primary Cultures and Stem Cells. ACS nano. 18(6), 4822-4839, 2024. [JCR]　[WOS]
(Huang YS)*, Mendez R*, Fernandez M, Richter JD*. CPEB and translational control by cytoplasmic polyadenylation: impact on synaptic plasticity, learning, and memory. Molecular psychiatry. , 2023. [JCR]　[WOS]
Lu WH, Chang TT, Chang YM, Liu YH, Lin CH, Suen CS, Hwang MJ, (Huang YS)*. CPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity. Journal of biomedical science. 31(1), 69, 2024. [JCR]　[WOS]
Lu WH, Chen HF, King PC, Peng C, Huang YS*. CPEB2-activated Prdm16 translation promotes brown adipocyte function and prevents obesity. Molecular metabolism. 89, 102034, 2024.
Chen YC, Sargsyan K, Wright JD, Chen YH, Huang YS, Lim C. PPI-hotspot(ID) for detecting protein-protein interaction hot spots from the free protein structure. eLife. 13, RP96643, 2024.
Tseng CS, Chao YW, Liu YH, (Huang YS)*, Chao HW*. Dysregulated proteostasis network in neuronal diseases. Frontiers in cell and developmental biology. 11, 1075215, 2023. [JCR]　[WOS]
Tsukamoto Y, Hiono T, Yamada S, Matsuno K, Faist A, Claff T, Hou J, Namasivayam V, Vom Hemdt A, Sugimoto S, Ng JY, Christensen MH, Tesfamariam YM, Wolter S, Juranek S, Zillinger T, Bauer S, Hirokawa T, Schmidt FI, Kochs G, Shimojima M, (Huang YS), Pichlmair A, Kummerer BM, Sakoda Y, Schlee M, Brunotte L, Muller CE, Igarashi M, Kato H. Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. SCIENCE. 379(6632), 586-591, 2023. [JCR]　[WOS]
Winkler I, Engler JB, Vieira V, Bauer S, Liu YH, Di Liberto G, Grochowska KM, Wagner I, Bier J, Bal LC, Rothammer N, Meurs N, Egervari K, Schattling B, Salinas G, Kreutz MR, (Huang YS), Pless O, Merkler D, Friese MA. MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration. Science advances. 9(47), eadi6855, 2023. [JCR]　[WOS]
Wu CS, Lu WH, Hung MC, (Huang YS)*, Chao HW*. From polyploidy to polyploidy reversal: its role in normal and disease states. Trends in genetics : TIG. 38(10), 991-995, 2022. [JCR]　[WOS]
Lai HH, Hung LY, Yen CJ, Hung HC, Chen RY, Ku YC, Lo HT, Tsai HW, Lee YP, Yang TH, Chen YY, Huang YS, Huang W. NEIL3 promotes hepatoma epithelial-mesenchymal transition by activating the BRAF/MEK/ERK/TWIST signaling pathway. The Journal of pathology. 258(4), 339-352, 2022. [JCR]　[WOS]
Huang DF, Lee CY, Chou MY, Yang TY, Cao X, Hsiao YH, Wu RN, Lien CC, (Huang YS), Huang HP, Gau SS, Huang HS. Neuronal splicing regulator RBFOX3 mediates seizures via regulating Vamp1 expression preferentially in NPY-expressing GABAergic neurons. Proceedings of the National Academy of Sciences of the United States of America. 119(33), e2203632119, 2022. [JCR]　[WOS]
Lu WH, Chang YM, (Huang YS*). Alternative Polyadenylation and Differential Regulation of Ucp1: Implications for Brown Adipose Tissue Thermogenesis Across Species. Frontiers in pediatrics. 8, 612279, 2021. [JCR]　[WOS]
Lu WH, Chao HW, Lin PY, Lin SH, Liu TH, Chen HW, (Huang YS*). CPEB3-downregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice. Neuropsychopharmacology. 46, 1669-1679, 2021. [JCR]　[WOS]
Bhore N, Wang BJ, Wu PF, Lee YL, Chen YW, Hsu WM, Lee H, (Huang YS), Yang DI, Liao YF. Dual-Specificity Phosphatase 15 (DUSP15) Modulates Notch Signaling by Enhancing the Stability of Notch Protein. Molecular neurobiology. 58(5), 2204-2214, 2021. [JCR]　[WOS]
Chen YD, Huang PY, Chiang CS, (Huang YS*), Tang SC*. Generation and Role of Calpain-Cleaved 17-kDa Tau Fragment in Acute Ischemic Stroke. Molecular neurobiology. 58(11), 5814-5825, 2021. [JCR]　[WOS]
Chiang CS, Fu SJ, Hsu CL, Jeng CJ, Tang CY, (Huang YS), Tang SC. Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth. Neuromolecular medicine. DOI: 10.1007/s12017-020-08641-z, 2021. [JCR]　[WOS]
Chiang SY, Wu HC, Lin SY, Chen HY, Wang CF, Yeh NH, Shih JH, (Huang YS), Kuo HC, Chou SJ, Chen RH. Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization. Science advances. 7(7), eabc6093, 2021. [JCR]　[WOS]
Lee YL, Kung FC, Lin CH, (Huang YS)*. CMTR1-Catalyzed 2′-O-Ribose Methylation Controls Neuronal Development by Regulating Camk2α Expression Independent of RIG-I Signaling. Cell Reports. 33(3), 108269, 2020. [JCR]　[WOS]
Lai YT, Chao HW, Lai A C-Y, Lin SH, Chang YJ, (Huang YS*). CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis. Journal of Biomedical Science. 27(1), 52, 2020. [JCR]　[WOS]
Bender CL, Sun X, Farooq M, Yang Q, Davison C, Maroteaux M, (Huang YS), Ishikawa Y, Liu SJ. Emotional Stress Induces Structural Plasticity in Bergmann Glial Cells via an AC5–CPEB3–GluA1 Pathway. The Journal of Neuroscience. 40(17), 3374-3384, 2020. [JCR]　[WOS]
Wu PF, Bhore N, Lee YL, Chou JY, Chen YW, Wu PY, Hsu WM, Lee H, (Huang YS), Lu PJ, Liao YF. Phosphatidylinositol‐4‐phosphate 5‐kinase type 1α attenuates Aβ production by promoting non‐amyloidogenic processing of amyloid precursor protein. The FASEB Journal. 34(9), 12127-12146, 2020. [JCR]　[WOS]
Pascual R, Martín J, Salvador F, Reina O, Chanes V, Millanes-Romero A, Suñer C, Fernández-Miranda G, Bartomeu A, (Huang YS), Gomis RR, Méndez R. The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer. Science Advances. 6(20), eaax3868, 2020. [JCR]　[WOS]
Tseng CS, Chou SJ, (Huang YS*). CPEB4-Dependent Neonate-Born Granule Cells Are Required for Olfactory Discrimination. Frontiers in behavioral neuroscience. 13, 5, 2019-01. [JCR]　[WOS]
Chen YC, Chang YW, (Huang YS*). Dysregulated Translation in Neurodevelopmental Disorders: An Overview of Autism-Risk Genes Involved in Translation. Developmental neurobiology. 79(1), 60-74, 2019-01. [JCR]　[WOS]
Chen HF, Hsu CM, (Huang YS*). CPEB2-dependent translation of long 3\'-UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue. The EMBO journal. 37(20), 2018. [JCR]　[WOS]
(Huang YS*), Lu WH. Decoding hidden messages in neurons: insights from epitranscriptome-controlled and specialized ribosome-controlled translation. Current opinion in neurobiology. 48, 64-70, 2018. [JCR]　[WOS]
Wang KC, Tang SC, Lee JE, Li YI, (Huang YS), Yang WS, Jeng JS, Arumugam TV, Tu YK. Cerebrospinal fluid high mobility group box 1 is associated with neuronal death in subarachnoid hemorrhage. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 37(2), 435-443, 2017. [JCR]　[WOS]
Lu WH, Yeh NH, (Huang YS*). CPEB2 Activates GRASP1 mRNA Translation and Promotes AMPA Receptor Surface Expression, Long-Term Potentiation, and Memory. Cell reports. 21(7), 1783-1794, 2017. [JCR]　[WOS]
Chang YW, (Huang YS*). Midbody localization of vinexin recruits rhotekin to facilitate cytokinetic abscission. Cell cycle (Georgetown, Tex.). 16(21), 2046-2057, 2017. [JCR]　[WOS]
Lai YT, (Huang YS*). Modification and application of a commercial whole-body plethysmograph to monitor respiratory abnormalities in neonatal mice. Bio protocol. 7(12), e2343, 2017. [JCR]　[WOS]
Tseng CS, Chao HW, Huang HS, (Huang YS*). Olfactory-Experience- and Developmental-Stage-Dependent Control of CPEB4 Regulates c-Fos mRNA Translation for Granule Cell Survival. Cell reports. 21(8), 2264-2276, 2017. [JCR]　[WOS]
Chen CY, Chen YT, Wang JY, (Huang YS*), Tai CY*. Postsynaptic Y654 dephosphorylation of beta-catenin modulates presynaptic vesicle turnover through increased n-cadherin-mediated transsynaptic signaling. Developmental neurobiology. 77, 61-74, 2017. [JCR]　[WOS]
Li J, Tseng CS, Federico A, Ivankovic F, (Huang YS), Ciccodicola A, Swanson MS, Yu P. SFMetaDB: a comprehensive annotation of mouse RNA splicing factor RNA-Seq datasets. Database-The Journal of Biological Databases and Curation. bax071, 2017. [JCR]　[WOS]
Tsai LY, Chang YW, Lee MC, Chang YC, Hwang PI, (Huang YS*), Cheng CF*. Biphasic and Stage-Associated Expression of CPEB4 in Hepatocellular Carcinoma. PloS one. 11, e0155025, 2016. [JCR]　[WOS]
Fong SW, Lin HC, Wu MF, Chen CC, (Huang YS*). CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation. PloS one. 11, e0148491, 2016. [JCR]　[WOS]
Lai YT, Su CK, Jiang ST, Chang YJ, Lai AC, (Huang YS*). Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(50), 12661-12676, 2016. [JCR]　[WOS]
Chen YP, Bai GS, Wu MF, Chiao CC, (Huang YS*). Loss of CPEB3 Upregulates MEGF10 to Impair Mosaic Development of ON Starburst Amacrine Cells. Frontiers in molecular neuroscience. 9, 105, 2016. [JCR]　[WOS]
Chen PJ, Weng JY, Hsu PH, Shew JY, (Huang YS*), Lee WH*. NPGPx modulates CPEB2-controlled HIF-1alpha RNA translation in response to oxidative stress. Nucleic acids research. 43, 9393-9404, 2015. [JCR]　[WOS]
Chen YC, Sargsyan K, Wright JD, (Huang YS*), Lim C*. Identifying RNA-binding residues based on evolutionary conserved structural and energetic features. Nucleic acids research. 42, e15, 2014-02. [JCR]　[WOS]
Chang YW, (Huang YS*). Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. PloS one. 9(9), e107961, 2014. [JCR]　[WOS]
Huang WH, Chao HW, Tsai LY, Chung MH, (Huang YS*). Elevated activation of CaMKIIalpha in the CPEB3-knockout hippocampus impairs a specific form of NMDAR-dependent synaptic depotentiation. Frontiers in cellular neuroscience. 8, 367, 2014. [JCR]　[WOS]
Tsai LY, Chang YW, Lin PY, Chou HJ, Liu TJ, Lee PT, Huang WH, Tsou YL, (Huang YS*). CPEB4 Knockout Mice Exhibit Normal Hippocampus-Related Synaptic Plasticity and Memory. PloS one. 8(12), e84978, 2013. [JCR]　[WOS]
Chao HW, Tsai LY, Lu YL, Lin PY, Huang WH, Chou HJ, Lu WH, Lin HC, Lee PT, (Huang YS*). Deletion of CPEB3 enhances hippocampus-dependent memory via increasing expressions of PSD95 and NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(43), 17008-22, 2013. [JCR]　[WOS]
Tang SC, Wang YC, Li YI, Lin HC, Manzanero S, Hsieh YH, Phipps S, Hu CJ, Chiou HY, (Huang YS), Yang WS, Mattson MP, Arumugam TV, Jeng JS. Functional role of soluble receptor for advanced glycation end products in stroke. Arteriosclerosis Thrombosis and Vascular Biology. 33(3), 585-594, 2013. [JCR]　[WOS]
Chao HW, Lai YT, Lu YL, Lin CL, Mai W, (Huang YS*). NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3. Nucleic acids research. 40(17), 8484-8498, 2012-09. [JCR]　[WOS]
Wang CF, (Huang YS*). Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons. Molecular and cellular biology. 32(16), 3321-3332, 2012-08. [JCR]　[WOS]
Chen PJ, (Huang YS*). CPEB2-eEF2 interaction impedes HIF-1alpha RNA translation. The EMBO journal. 31(4), 959-71, 2012. [JCR]　[WOS]
Peng SC, Lai YT, Huang HY, Huang HD, (Huang YS*). A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Nucleic acids research. 38(21), 7446-57, 2010. [JCR]　[WOS]
Lin AC., Tan CL., Lin CL., Strochlic L, (Huang YS), Richter JD. and Holt CE. Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development. Neural Development. 4, 8, 2009-03. [JCR]　[WOS]
(Huang YS*), Richter JD. Analysis of mRNA translation in cultured hippocampal neurons. Methods in enzymology. 431, 143-62, 2007. [JCR]　[WOS]
(Huang YS), Kan MC, Lin CL, Richter JD. CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA. The EMBO journal. 25(20), 4865-76, 2006. [JCR]　[WOS]
Cao Q, (Huang YS), Kan MC, Richter JD. Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation. Molecular and cellular biology. 25(24), 10930-9, 2005. [JCR]　[WOS]
(Huang YS), Richter JD. Regulation of local mRNA translation. Current opinion in cell biology. 16(3), 308-13, 2004. [JCR]　[WOS]
Alarcon JM, Hodgman R, Theis M, (Huang YS), Kandel ER, Richter JD. Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene. Learning & memory (Cold Spring Harbor, N.Y.). 11(3), 318-27, 2004. [JCR]　[WOS]
Song JL, Li J, (Huang YS), Chuang DT. Encapsulation of an 86-kDa assembly intermediate inside the cavities of GroEL and its single-ring variant SR1 by GroES. The Journal of biological chemistry. 278(4), 2515-21, 2003. [JCR]　[WOS]
(Huang YS), Carson JH, Barbarese E, Richter JD. Facilitation of dendritic mRNA transport by CPEB. Genes & development. 17(5), 638-53, 2003. [JCR]　[WOS]
(Huang YS), Jung MY, Sarkissian M, Richter JD. N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapses. The EMBO journal. 21(9), 2139-48, 2002. [JCR]　[WOS]
Wells DG, Dong X, Quinlan EM, (Huang YS), Bear MF, Richter JD, Fallon JR. A role for the cytoplasmic polyadenylation element in NMDA receptor-regulated mRNA translation in neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(24), 9541-8, 2001. [JCR]　[WOS]
Groisman I, (Huang YS), Mendez R, Cao Q, Richter JD. Translational control of embryonic cell division by CPEB and maskin. Cold Spring Harbor symposia on quantitative biology. 66, 345-51, 2001. [JCR]　[WOS]
Groisman I, (Huang YS), Mendez R, Cao Q, Theurkauf W, Richter JD. CPEB, maskin, and cyclin B1 mRNA at the mitotic apparatus: implications for local translational control of cell division. Cell. 103(3), 435-47, 2000. [JCR]　[WOS]
(Huang YS), Chuang DT. Regulation of branched-chain alpha-keto acid dehydrogenase kinase gene expression by glucocorticoids in hepatoma cells and rat liver. Methods in Enzymology. 324, 498-511, 2000. [JCR]　[WOS]
(Huang YS), Chuang DT. Down-regulation of rat mitochondrial branched-chain 2-oxoacid dehydrogenase kinase gene expression by glucocorticoids. The Biochemical journal. 339 ( Pt 3), 503-10, 1999. [JCR]　[WOS]
(Huang YS), Chuang DT. Mechanisms for GroEL/GroES-mediated folding of a large 86-kDa fusion polypeptide in vitro. The Journal of biological chemistry. 274(15), 10405-12, 1999. [JCR]　[WOS]
(Huang YS), Chuang DT. Mechanism for basal expression of rat mitochondrial branched-chain-2-oxo-acid dehydrogenase kinase [corrected]. The Biochemical journal. 334 ( Pt 3), 713-22, 1998. [JCR]　[WOS]
(Huang Y), Chuang DT. Structural organization of the rat branched-chain 2-oxo-acid dehydrogenase kinase gene and partial characterization of the promoter-regulatory region. The Biochemical journal. 313 ( Pt 2), 603-9, 1996. [JCR]　[WOS]
Davie JR, Wynn RM, Meng M, (Huang YS), Aalund G, Chuang DT, Lau KS. Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?. The Journal of biological chemistry. 270(34), 19861-7, 1995. [JCR]　[WOS]
Wu HN, Lee JY, Huang HW, (Huang YS), Hsueh TG. Mutagenesis analysis of a hepatitis delta virus genomic ribozyme. Nucleic acids research. 21(18), 4193-9, 1993. [JCR]　[WOS]

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