中央研究院生命科學圖書館 -- 生命組研究成果

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生命組研究成果

生物醫學科學研究所 - 陳建璋 Chen, Chien-Chang

期刊 57

Tamang, H.K., Yang, R.B., Song, Z.H., Hsu, S.C., Peng, C.C, Tung, Y.C, Tzeng, B.H.*, and (Chen, C.C.)*. Cav3.2 T‐type calcium channel regulates mouse platelet activation and arterial thrombosis. Journal of Thrombosis and Haemostasis. , 2022-05-01. [JCR]　[WOS]
Hu, Y.F., Lee, A.S., Chang, S.L., Lin, S.F., Weng, C.H., Lo, H.Y., Chou, P.C., Tsai, Y.N., Sung, Y.L., (Chen, C.C.), Yang, R.B., Lin, Y.C. Kuo, T.B., Wu, C.H., Liu, J.D., Chung, T.W., & Chen, S.A. Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats. Nature Biomedical Engineering. , 2021-11-22. [JCR]　[WOS]
Chang, Y.W., Song, Z.H. & (Chen, C.C.)*. FAK regulates cardiomyocyte mitochondrial fission and function through Drp1. FEBS JOURNAL. , 2021-11-05. [JCR]　[WOS]
Mindaye Selomon Assefa, Chen Wei-Hsin, Lin Shih-Che, Chen Yong-Cyuan, Abdelaziz Mohamed Abbas, Tzeng Yi-Shiuan, Shih Arthur Chun-Chieh, Chen Shih-Yu, Yang Shi-Bing, Chen Chien-Chang. Separate anterior paraventricular thalamus projections differentially regulate sensory and affective aspects of pain. Cell Reports. 43(11), 114946, 2024-11. [JCR]
Abdelaziz Mohamed Abbas, Chen Wei-Hsin, Chang Yu-Wang, Mindaye Selomon Assefa, (Chen Chien-Chang)*. Exploring the role of spinal astrocytes in the onset of hyperalgesic priming signals in acid-induced chronic muscle pain. PNAS Nexus. 3(9), 362, 2024-08-30. [JCR]　[WOS]
Tsai Min-Chien, Cho Rou-Ling, Lin Chin-Sheng, Jheng Yu-Sin, Lien Chih-Feng, (Chen Chien-Chang), Tzeng Bing-Hsiean. Cav3.1 T-type calcium channel blocker NNC 55-0396 reduces atherosclerosis by increasing cholesterol efflux. Biochemical Pharmacology. 222, 116096, 2024-04. [JCR]　[WOS]
Lin Chia-Yeh, Chang Yao-Ming, Tseng Hsin-Yi, Shih Yen-Ling, Yeh Hsiao-Hui, Liao You-Rou, Tang Han-Hsuan, Hsu Chia-Ling, (Chen Chien-Chang), Yan Yu-Ting, Kao Cheng-Fu. Epigenetic regulator RNF20 underlies temporal hierarchy of gene expression to regulate postnatal cardiomyocyte polarization. Cell Reports. 42(11), 113416, 2023-11. [JCR]　[WOS]
Chang Yu-Wang, Chen Yong-Cyuan, (Chen Chien-Chang)*. Identification of Novel Targeting Sites of Calcineurin and CaMKII in Human CaV3.2 T-Type Calcium Channel. Biomedicines. 11(11), 2891, 2023-10-25. [JCR]　[WOS]
Yeh Hsiao-hui, Chang Yao-Ming, Chang Yu-Wang, Lu Mei-Yeh Jade, Chen Yi-Hua, Lee Chia-Che, Chen Chien-Chang. Multiomic analyses reveal enriched glycolytic processes in β-myosin heavy chain-expressed cardiomyocytes in early cardiac hypertrophy. Journal of Molecular and Cellular Cardiology Plus. 1, 100011, 2022-09. [JCR]
Suresh, P., Jasmin, S., Yen, Y., Hsu, H.J.,Varinthra, P., Pairojana, T., (Chen, C.C). and Liu, I.Y.*. Attenuation of HECT-E3ligase expression rescued memorydeficits in 3xTg-AD mice. Front. Aging Neurosci.. 14, 91690, 2022-07-29.
Herzig, V.*†, Chen, Y.C.,†, Chin, Y.K.Y., Dekan, Z., Chang, Y-W, Yu, H.M., Alewood, P.F., (Chen, C.C),* and King, G.F.*. The Tarantula Toxin ω-Avsp1a Specifically Inhibits Human CaV3.1 and CaV3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor. biomedicines. 10(5), 1066, 2022-05-04. [JCR]　[WOS]
Chen, W.H., Lien, C.C., (Chen, C.C.)*. Neuronal basis for pain- and anxiety-like behaviors in the central nucleus of the amygdala. PAIN. 163(3), e463-e475, 2022-03-01. [JCR]　[WOS]
Brandon-Mong, GJ; Shaw, GTW; Chen, WH; (Chen, CC); Wang, DR. A network approach to investigating the key microbes and stability of gut microbial communities in a mouse neuropathic pain model. BMC MICROBIOLOGY. 20(1), 295, 2020-09-30. [JCR]　[WOS]
Chang, C.S., Liao, C.C., Liou, A.T., Chang, Y.S., Chang, Y.T., Tzeng, B.H., (Chen, C.C.), & Shih, C. Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model. SCIENTIFIC REPORTS. 9(1):11108, 2019-07-31. [JCR]　[WOS]
Chang, Y.T., Chen, W.H., Shih, H.C., Shyu, B.C., Min, M.Y. & (Chen, C.C.). Anterior nucleus of paraventricular thalamus mediates chronic mechanical hyperalgesia. PAIN. 160(5), 1208-1223, 2019-05. [JCR]　[WOS]
Hsieh, F.C., Lu, Y.F., (Chen, C.C.), Cheng, C.M., Hsiao C.D. & Hwang S. P. Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells. SCIENTIFIC REPORTS. 8, 7856, 2018-05-18. [JCR]　[WOS]
Chen, W.H., Chang, Y.T., Cheng, S.J. ; Chen, C.C. Spinal protein kinase C/extracellular signal–regulated kinase signal pathway mediates hyperalgesia priming. PAIN. 159(5), 907-918, 2018. [JCR]　[WOS]
Cheng#, Y.F., Chang#, Y.T., Chen, W.H., Shih, H.C., Chen, Y.H., Shyu, B.C. & (Chen, C.C.)*. Cardioprotection induced in mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus. Nature Communications. 8, Article number: 826, 2017-, 2017-10. [JCR]　[WOS]
Wu, Y.S., (Chen, C.C.), Chien, C.L., Lai, H.L., Jiang, S.T., Chen, Y.C., Lai, L.P., Chen, W.P. & Chern, Y. The type VI adenylyl cyclase protects cardiomyocytes from β-adrenergic stress by a PKA/STAT3-dependent pathway. JOURNAL OF BIOMEDICAL SCIENCE. 24(1), 68, 2017-09-04. [JCR]　[WOS]
Chang,Y.M., Ling, L., Chang, Y.T., Chang, Y.W., Li, W.H., Shih, A.C.C.* & (Chen, C.C.)*. Three TF Co-expression Modules Regulate Pressure-Overload Cardiac Hypertrophy in Male Mice. Scientific Reports. 7(1), 7560, 2017-08. [JCR]　[WOS]
Chung NC, Huang YH, Chang CH, Liao JC, Yang CH, (Chen CC), Liu IY. Behavior training reverses asymmetry in hippocampal transcriptome of the cav3.2 knockout mice. PloS one. 10(3), e0118832, 2015. [JCR]　[WOS]
Lee, D. S., Chen, J.H., Lundy, D.J., Liu, C.H., Hwang, S.M., Pabon, L., Shieh, R.C., (Chen, C.C.), Wu, S.N., Yan, Y.T., Lee, S.T., Chiang, P.M., Chien, S., Murry,C.E., & Hsieh, P.C.H. . Defined MicroRNAs Induce Aspects of Maturation in Mouse and Human Embryonic-Stem-Cell-Derived Cardiomyocytes. Cell Reports. 12(12), 1960-1967, 2015. [JCR]　[WOS]
Hsiao YF, Pan HJ, Tung YC, (Chen CC)*, Lee CH*. Effects of hydraulic pressure on cardiomyoblasts in a microfluidic device. Biomicrofluidics. 9(2), 024111, 2015. [JCR]　[WOS]
Lin, S.S., Tzeng, B.H., Lee, K.R., Smith, R.J., Campbell, K.P. & (Chen, C.C.)*. Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 111(19), E1990-E1998, 2014 May 1. [JCR]　[WOS]
Lee, S.E., Lee, J., Latchoumane, C., Lee, B., Oh, S.J., Alam Saud, Z., Park, C., Sun, N., Cheong, E., (Chen, C.C.), Choi, E.J., Lee, C. J. & Shin, H. S. Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 111(32), 11828-11833, 2014-08. [JCR]　[WOS]
Lin, C.C., Chang, Y.M., Pan, C.T., (Chen, C.C)., Ling, L., Tsao,K.C., Yang, R.B.,& Li, W.H. Functional Evolution of cardiac microRNAs in heart development and functions. MOLECULAR BIOLOGY AND EVOLUTION. 31(10), 2722-2734, 2014-07. [JCR]　[WOS]
Chang, Y.W., Chang, Y.C., Wang, Q., Lin, J., Chen,Y.J. & (Chen,C.C)*. Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy. MOLECULAR & CELLULAR PROTEOMICS. 12(11), 3094-3107, 2013-11. [JCR]　[WOS]
Hsu SC, Chang YT, (Chen CC)*. Early Growth Response 1 is an Early Signal Inducing Cav3.2 T-type Calcium Channels During Cardiac Hypertrophy. CARDIOVASCULAR RESEARCH. 100(2), 222-230, 2013-08. [JCR]　[WOS]
Huang, C.H., Chen, Y.C. & (Chen,C.C)*. Physical interaction between calcineurin and Cav3.2 T-type Ca2+ channel modulates their functions. . FEBS LETTERS. 587(12), 1723-1730, 2013-06. [JCR]　[WOS]
Tzeng, B.H., Chen, Y.H., Huang, C.H., Lin, S.S., Lee, K.R., and (Chen, C.C.)*. The Cav3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice. CARDIOVASCULAR RESEARCH. 96(3), 533-542, 2012-08. [JCR]　[WOS]
(Chen, C.C.), Shen, J.W., Chung, N.C., Min. M.Y., Cheng, S.J. & Liu, I. Y. Retrieval of context-associated memory is dependent on the Cav3.2 T-type calcium channel . PLoS One. 7(1), e29384, 2012. [JCR]　[WOS]
Liao, Y.F., Tsai, M.L., (Chen, C.C.) & Yen, C.T. Involvement of the Cav3.2 T-type Calcium Channel in Thalamic Neuron Discharge Patterns. Molecular Pain. 7, 43, 2011-06. [JCR]　[WOS]
(Chen, C.C.), Fan, Y.P., Shin, H.-S. & Su, C.K. Basal sympathetic activity generated in neonatal mouse brainstem-spinal cord preparation requires T-type calcium channel subunit a1H. Exp Physiol. 96(5), 486-494, 2011-05. [JCR]　[WOS]
Lei, D., Gao, X., Perez, P., Ohlemiller, K.K., (Chen, C.C.), Campbell, K.P., Hood, A.Y. & Bao, J. Anti-epileptic drugs delay age-related loss of spiral ganglion neurons via T-type calcium channel. Hearing Research. 278(1-2), 106-112, 2011. [JCR]　[WOS]
Cheng,S. J., (Chen,C.C.), Yang, H.W., Chang, Y.T., Bai,S.W., Chen,C.C., Yen,C.T. & Min, M.Y. (2011) . Role of extracellular signal-regulated kinase in synaptic transmission and plasticity of a nociceptive input on capsular central amygdaloid neurons in normal and acid-induced muscle pain mice. JOURNAL OF NEUROSCIENCE. 31, 2258-2270, 2011. [JCR]　[WOS]
Alnawaiseh, M., Albanna, W., (Chen, C.C.), Campbell, K.P., Hescheler, J., Lüke, M. & Schneider T. . Two separate Ni2+ -sensitive voltage gated Ca2+ channels modulate transretinal signalling in the isolated murine retina. Acta Ophthalmol. 89(7), E579-E590, 2011. [JCR]　[WOS]
Chen, W.G., Liu,I.Y., Chang, Y.T., Chen, Y.C., Chen,C.C., Yen, C.T., Shin, H.-S., & (Chen, C.C.)*. Cav3.2 T-type Ca2+ channel dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain. . JOURNAL OF NEUROSCIENCE. 30(31), 10360-10368., 2010-08. [JCR]　[WOS]
Su, C.K*., Fan, Y.P., (Chen,C.C.), Chern,Y. . Supraspinal contribution to splanchnic sympathetic activity in neonatal mouse and rat brainstem-spinal cord in vitro. AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL. 156(1-2), 51-59, 2010-08. [JCR]　[WOS]
Lin, H, Sue, Y.M., Chou, Y., Cheng, C.F., Chang, C.C., Li, H.F., (Chen, C.C.), Juan, S.H. Activation of a nuclear factor of activated T-lymphocyte-3 (NFAT3) by oxidative stress in carboplatin-mediated renal apoptosis. BRITISH JOURNAL OF PHARMACOLOGY. 161(7), 1661-1676, 2010. [JCR]　[WOS]
Lin CH, (Chen CC), Chou CM, Wang CY, Hung CC, Chen JY, Chang HW, Chen YC, Yeh GC, Lee YH*. Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA-induced BDNF expression in cortical neurons. J Neurochem. 111(3), 777-789, 2009-11. [JCR]　[WOS]
Chiang, C.S. Huang, C. H., Chieng, H.L, Chang, Y.T., Chang, D., Chen, J.J., Chen, Y.C., Chen, Y.H., Shin, H.-S., Campbell, K.P., & (Chen, C.C.)*. The CaV3.2 T-type Ca2+ Channel is Required for Pressure Overload-Induced Cardiac Hypertrophy in Mice. Circulation Research. 104(4), 522-530, 2009-02. [JCR]　[WOS]
M. L. Tsai, J. J. Huang, L. M. Chou and (C. C. Chen). A home-made low-cost hydraulic swivel and catheter assembly for blood pressure recording and drug infusion in freely moving mice. J Physiol Sci. (in press), 2008. [JCR]　[WOS]
A. J. Becker, J. Pitsch, D. Sochivko, T. Opitz, M. Staniek,(C. C. Chen), K. P. Campbell S. Schoch, Y. Yaari and H. Beck. Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy. JOURNAL OF NEUROSCIENCE. 28(49), 13341-13353, 2008. [JCR]　[WOS]
X. F. Figueroa, (C. C. Chen), K. P. Campbell, D. N. Damon, K. H. Day, S. Ramos and B. R. Duling. Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 293, H1371-H1383, 2007. [JCR]　[WOS]
J. Escoffier, S. Boisseau, C. Serres, (C. C. Chen), D. Kim, S. Stamboulian, H. S. Shin, K. P. Campbell, M. De Waard and C. Arnoult. Expression, localization and functions in acrosome reaction and sperm motility of Ca(V)3.1 and Ca(V)3.2 channels in sperm cells: an evaluation from Ca(V)3.1 and Ca(V)3.2 deficient mice. J Cell Physiol. 212(3), 753-763, 2007. [JCR]　[WOS]
M. G. Kang, (C. C. Chen), M. Wakamori, Y. Hara, Y. Mori and K. P. Campbell. A functional AMPA receptor-calcium channel complex in the postsynaptic membrane. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 103, 5561-5566, 2006. [JCR]　[WOS]
P. M. Joksovic, M. T. Nelson, V. Jevtovic-Todorovic, M. K. Patel, E. Perez-Reyes, K. P. Campbell, (C. C. Chen) and S. M. Todorovic. CaV3.2 is the major molecular substrate for redox regulation of T-type Ca2+ channels in the rat and mouse thalamus. JOURNAL OF PHYSIOLOGY-LONDON. 574, 415-430, 2006. [JCR]　[WOS]
J. K. Larsen, (C. C. Chen) and P. M. Best. Disruption of growth hormone secretion alters Ca2+ current density and expression of Ca2+ channel and insulin-like growth factor genes in rat atria. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 288, H829-H838, 2005. [JCR]　[WOS]
P. J. Chu, J. K. Larsen, (C. C. Chen) and P. M. Best. Distribution and relative expression levels of calcium channel beta subunits within the chambers of the rat heart. J Mol Cell Cardiol. 36, 423-434, 2004. [JCR]　[WOS]
Y. Opatowsky, (C. C. Chen), K. P. Campbell and J. A. Hirsch. Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain. Neuron. 42, 387-399, 2004. [JCR]　[WOS]
(C. C. Chen), K. G. Lamping, D. W. Nuno, R. Barresi, S. J. Prouty, J. L. Lavoie, L. L. Cribbs, S. K. England, C. D. Sigmund, R. M. Weiss, R. A. Williamson, J. A. Hill and K. P. Campbell. Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels. Science. 302, 1416-1418, 2003. [JCR]　[WOS]
D. Bansal, K. Miyake, S. S. Vogel, S. Groh, (C. C. Chen), R. Williamson, P. L. McNeil and K. P. Campbell. Defective membrane repair in dysferlin-deficient muscular dystrophy. Nature. 423, 168-172, 2003. [JCR]　[WOS]
J. Arikkath, (C. C. Chen), C. Ahern, V. Allamand, J. D. Flanagan, R. Coronado, R. G. Gregg and K. P. Campbell. Gamma 1 subunit interactions within the skeletal muscle L-type voltage-gated calcium channels. J Biol Chem. 278, 1212-1219, 2003. [JCR]　[WOS]
J. Arikkath, R. Felix, C. Ahern, (C. C. Chen), Y. Mori, I. Song, H. S. Shin, R. Coronado and K. P. Campbell. Molecular characterization of a two-domain form of the neuronal voltage-gated P/Q-type calcium channel alpha(1)2.1 subunit. FEBS Lett. 532, 300-308, 2002. [JCR]　[WOS]
M. G. Kang, (C. C. Chen), R. Felix, V. A. Letts, W. N. Frankel, Y. Mori and K. P. Campbell. Biochemical and biophysical evidence for gamma 2 subunit association with neuronal voltage-activated Ca2+ channels. J Biol Chem. 276, 32917-32924, 2001. [JCR]　[WOS]
E. S. Piedras-Renteria, (C. C. Chen) and P. M. Best. Antisense oligonucleotides against rat brain alpha1E DNA and its atrial homologue decrease T-type calcium current in atrial myocytes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 94, 14936-14941, 1997. [JCR]　[WOS]
C. J. Huang, (C. C. Chen), H. J. Chen, F. L. Huang and G. D. Chang. A protease inhibitor of the serpin family is a major protein in carp perimeningeal fluid: I. Protein purification and characterization. J Neurochem. 64, 1715-1720, 1995. [JCR]　[WOS]

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