生命組研究成果
期刊 19
- Hui-Ni Tan, Wei-Qi Liu, Josh Ho, Yi-Ju Chen, Fang-Jie Shieh, Hsiao-Tzu Liao, (Shu-Ping Wang), Julian D. Hegemann, Chin-Yuan Chang, John Chu*. Structure Prediction and Protein Engineering Yield New Insights into Microcin J25 Precursor Recognition. ACS CHEMICAL BIOLOGY. 19(9), 1982-1990, 2024-09-20. [JCR] [WOS]
- Yi Zhang, Guojia Xie, Ji-Eun Lee, Mohamad Zandian, Deepthi Sudarshan, Benjamin Estavoyer, Caroline Benz, Tiina Viita, Golareh Asgaritarghi, Catherine Lachance, Clémence Messmer, Leandro Simonetti, Vikrant Kumar Sinha, Jean-Philippe Lambert, Yu-Wen Chen, (Shu-Ping Wang), Ylva Ivarsson, El Bachir Affar, Jacques Côté, Kai Ge, Tatiana G Kutateladze*. ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers. Nature Communications. 15(1), 4883, 2024-06-07. [JCR] [WOS]
- Vikrant Kumar Sinha,Yi Zhang, Longxia Xu, Yu-Wen Chen, Sarah Picaud, Mohamad Zandian, Soumi Biswas, Panagis Filippakopoulos, (Shu-Ping Wang), Xiaobing Shi, Tatiana G. Kutateladze*. Histone H4K16ac binding function of the triple PHD finger cassette of MLL4. Journal of Molecular Biology. 10.1016/, j.jmb.-2023.168212, 2023-07-20. [JCR] [WOS]
- Hsiang-Chi Huang, Shih-Han Wang, Guo-Chen Fang, Wen-Cheng Chou, Chun-Che Liao, Cheng-Pu Sun, Jia-Tsrong Jan, Hsiu-Hua Ma, Hui-Ying Ko, Yi-An Ko, Ming-Tsai Chiang, Jian-Jong Liang, Chun-Tse Kuo, Te-An Lee, Diego Morales-Scheihing, Chen-Yang Shen, Shih-Yu Chen, Louise D. McCullough, Lu Cui, Gerlinde Wernig, Mi-Hua Tao, Yi-Ling Lin, Yao-Ming Chang*, (Shu-Ping Wang*), Yun-Ju Lai*, Chia-Wei Li*. Upregulation of PD-L1 by SARS-CoV-2 promotes immune evasion. JOURNAL OF MEDICAL VIROLOGY. 2023;, 95:-e28478., 2023-01-07. [JCR] [WOS]
- Binay K. Sahoo, Yuh-Charn Lin, Cheng-Fen Tu, Chien-Chin Lin, Wei-Ju Liao, Fu-An Li, Ling-Hui Li, Kurt Yun Mou, Steve R. Roffler, (Shu-Ping Wang), Chi-Tai Yeh, Chi-Yuan Yao, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien and Ruey-Bing Yang. Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia. Haematologica. DOI:, 10.3324-/haematol.2022.281151, 2022-08-25. [JCR] [WOS]
- Lan-Hsin Wang, Marvin Angelo E. Aberin, Sean Wu, (Shu-Ping Wang)*. The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape. BIOCHEMICAL SOCIETY TRANSACTIONS. 49 (3), 1041-1054, 2021-06-22. [JCR] [WOS]
- Chia-Sing Lu, Ching-Wen Lin, Ya-Hsuan Chang, Hsuan-Yu Chen, Wei-Chia Chung, Wei-Yun Lai, Chao-Chi Ho, Tong-Hong Wang, Chi-Yuan Chen, Chen-En Yeh, Sean Wu, (Shu-Ping Wang)*, Pan-Chyr Yang*. Antimetabolite Pemetrexed Primes a Favorable Tumor Microenvironment for Immune Checkpoint Blockade Therapy. JOURNAL FOR IMMUNOTHERAPY OF CANCER. 8, e001392, 2020-11-26. [JCR] [WOS]
- Ting-Chun Kuo, Kuo-Yen Huang, Shuenn-Chen Yang, Sean Wu, Wei-Chia Chung, Yih-Leong Chang, Tse-Ming Hong, (Shu-Ping Wang), Hsuan-Yu Chen, Tzu-Hung Hsiao, Pan-Chyr Yang. Monocarboxylate Transporter 4 Is a Therapeutic Target in Non-small Cell Lung Cancer with Aerobic Glycolysis Preference. Molecular Therapy - Oncolytics. 18, 189-201, 2020-09. [JCR] [WOS]
- Liling Wan, Shasha Chong, Fan Xuan, Angela Liang, Xiaodong Cui, Leah Gates, Thomas S. Carroll, Yuanyuan Li, Lijuan Feng, Guochao Chen, (Shu-Ping Wang) , Michael V. Ortiz, Sara K. Daley, Xiaolu Wang, Hongwen Xuan, Alex Kentsis, Tom W. Muir, Robert G. Roeder, Haitao Li, Wei Li, Robert Tjian, Hong Wen, C. David Allis. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. 577(7788), 121-126, 2020-01. [JCR] [WOS]
- Yi Zhang , Younghoon Jang, Ji-Eun Lee, JaeWoo Ahn, Longxia Xu, Michael R. Holden, Evan M. Cornett, Krzysztof Krajewski, Brianna J. Klein, (Shu-Ping Wang), Yali Dou, Robert G. Roeder, Brian D. Strahl, Scott B. Rothbart, Xiaobing Shi, Kai Ge*, Tatiana G. Kutateladze*. Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF. NATURE COMMUNICATIONS. 10, 2314, 2019-05-24. [JCR] [WOS]
- Xiaomu Wei, M. Nieves Calvo-Vidal, Siwei Chen, Gang Wu, Maria V. Revuelta, Jian Sun, Jinghui Zhang, Michael F. Walsh, Kim E. Nichols, Vijai Joseph, Carrie Snyder, Celine M. Vachon, James D. McKay, (Shu-Ping Wang), David S. Jayabalan, Lauren M. Jacobs, Dina Becirovic, Rosalie G. Waller, Mykyta Artomov, Agnes Viale, Jayeshkumar Patel, Jude Phillip, Selina Chen-Kiang, Karen Curtin, Mohamed Salama, Djordje Atanackovic, Ruben Niesvizky, Ola Landgren, Susan L. Slager, Lucy A. Godley, Jane Churpek, Judy E. Garber, Kenneth C. Anderson, Mark J. Daly, Robert G. Roeder, Charles Dumontet, Henry T. Lynch, Charles G. Mullighan, Nicola J. Camp, Kenneth Offit, Robert J. Klein, Haiyuan Yu, Leandro Cerchietti, Steven M. Lipkin*. Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma. Cancer Research. 78(10), 2747-2759, 2018. [JCR] [WOS]
- Leah A. Gates, Guowei Gu, Yue Chen, Aarti D. Rohira, Jonathan T. Lei, Ross A. Hamilton, Yang Yu, David M. Lonard, Jin Wang, (Shu-Ping Wang), David G. Edwards, Philip F. Lavere, Jiangyong Shao, Ping Yi, Antrix Jain, Sung Yun Jung, Anna Malovannaya, Shunqiang Li, Jieya Shao, Robert G. Roeder, Matthew J. Ellis, Jun Qin, Suzanne A. W. Fuqua, Bert W. O’Malley, Charles E. Foulds*. Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets. Oncogene. 37(33), 4581-4598, 2018. [JCR] [WOS]
- (Shu-Ping Wang), Zhanyun Tang, Chun-Wei Chen, Miho Shimada, Richard P. Koche, Lan-Hsin Wang, Tomoyoshi Nakadai, Alan Chramiec, Andrei V. Krivtsov, Scott A. Armstrong, Robert G. Roeder*. A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription. Molecular Cell. 67(2), 308-321.e6, 2017. [JCR] [WOS]
- Shih-Han Kao, Wen-Lung Wang, Chi-Yuan Chen, Yih-Leong Chang, Yi-Ying Wu, Yi-Ting Wang, (Shu-Ping Wang), Alexey Nesvizhskii, Yu-Ju Chen, Tse-Ming Hong, Pan-Chyr Yang*. Analysis of Protein Stability by the Cycloheximide Chase Assay. BIO-PROTOCOL. 5(1), 1-7, 2016.
- Ching-Wen Lin, Lu-Kai Wang, (Shu-Ping Wang), Yi-Liang Chang, Yi-Ying Wu, Hsuan-Yu Chen, Tzu-Hung Hsiao, Wei-Yun Lai, Hsuan-Hsuan Lu, Ya-Hsuan Chang, Shuenn-Chen Yang, Ming-Wei Lin, Chi-Yuan Chen, Tse-Ming Hong, Pan-Chyr Yang*. Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis. Nature Communications. 7, 13867, 2016. [JCR] [WOS]
- (Shu-Ping Wang), Lan-Hsin Wang*. Disease implication of hyper-Hippo signalling. Open Biology. 6(10), 160119, 2016. [JCR] [WOS]
- Wen-Lung Wang, Hsiao-Chun Huang, Shih-Han Kao, Yi-Chiung Hsu, Yi-Ting Wang, Ker-Chau Li, Yu-Ju Chen, Sung-Liang Yu, (Shu-Ping Wang), Tzu-Hung Hsiao, Pan-Chyr Yang, Tse-Ming Hong*. Slug is temporally regulated by cyclin E in cell cycle and controls genome stability. Oncogene. 34(9), 1116-1125, 2014. [JCR] [WOS]
- Shih-Han Kao, Wen-Lung Wang, Chi-Yuan Chen, Yih-Leong Chang, Yi-Ying Wu, Yi-Ting Wang, (Shu-Ping Wang), Alexey I. Nesvizhskii, Yu-Ju Chen, Tse-Ming Hong*, Pan-Chyr Yang*. GSK3β controls epithelial–mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug. Oncogene. 33(24), 3172-3182, 2013. [JCR] [WOS]
- (Shu-Ping Wang), Wen-Lung Wang, Yih-Leong Chang, Chen-Tu Wu, Yu-Chih Chao, Shih-Han Kao, Ang Yuan, Chung-Wu Lin, Shuenn-Chen Yang, Wing-Kai Chan, Ker-Chau Li, Tse-Ming Hong*, Pan-Chyr Yang*. p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nature Cell Biology. 11(6), 694-704, 2009. [JCR] [WOS]