中央研究院生命科學圖書館 -- 生命組研究成果

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生命組研究成果

生物醫學科學研究所 - 胡哲銘 Hu, Che-Ming

期刊 65

Lim S-K, Lin W-C, Huang S-W, Pan Y-C, Hu C-W, Mou C-Y, 「Hu C-M*」, Mou K. Bacteria colonization in tumor microenvironment creates a favorable niche for immunogenic chemotherapy. EMBO MOLECULAR MEDICINE. , 2024. [JCR]　[WOS]
Lin Chi-Long, Fang Zih-Syun, Hsu Chung-Yao, Liu Yu-Han, Lin Jung-Chen, Yao Bing-Yu, Li Fu-An, Yen Shin-Chwen Bruce, Chang Yuan-Chih,「Hu Che-Ming J*」. Rapid plasma membrane isolation via intracellular polymerization-mediated biomolecular confinement. Acta Biomaterialia. 173, 325-335, 2024-01-01. [JCR]　[WOS]
Francisco Jamie, Guan Jin, Zhang Yu, Nakada Yasuki, Mareedu Satvik, Sung Eun-Ah, 「Hu Che-Ming」, Oka Shinichi, Zhai Peiyong, Sadoshima Junichi, Del Re Dominic P*. Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress. Journal of Molecular and Cellular Cardiology. 181, 1-14, 2023-08-01. [JCR]　[WOS]
Tsai Hsiao‐Han, Huang Ping‐Han, Lin Leon CW, Yao Bing‐Yu, Liao Wan‐Ting, Pai Chen‐Hsueh, Liu Yu‐Han, Chen Hui‐Wen*,「Hu Che‐Ming J*」. Lymph Node Follicle‐Targeting STING Agonist Nanoshells Enable Single‐Shot M2e Vaccination for Broad and Durable Influenza Protection. Advanced Science. 10(17), 2206521, 2023-04-24. [JCR]
Luis E. Contreras-Llano, Yu-Han Liu, Tanner Henson, Conary C. Meyer, Ofelya Baghdasaryan, Shahid Khan, Chi-Long Lin, Aijun Wang, (Che-Ming J. Hu*), Cheemeng Tan*. Engineering cyborg bacteria through intracellular hydrogelation. ADVANCED SCIENCE. e2204175, 2023. [JCR]　[WOS]
Chien Chen‐Ying, Lin Jung‐Chen, Huang Ching‐Ying, Hsu Chung‐Yao, Yang Kai‐Chieh, Chattopadhyay Saborni, Nikoloutsos Nicolas, Hsieh Patrick Ching‐Ho, (Hu Che‐Ming Jack*). In Situ Hydrogelation of Cellular Monolayers Enables Conformal Biomembrane Functionalization for Xeno‐Free Feeder Substrate Engineering. Advanced Healthcare Materials. 2022, 2201708, 2022-12-16. [JCR]
Chen Charles H., Liu Yu‐Han, Eskandari Arvin, Ghimire Jenisha, Lin Leon Chien‐Wei, Fang Zih‐Syun, Wimley William C., Ulmschneider Jakob P., Suntharalingam Kogularamanan, Hu Che‐Ming Jack, Ulmschneider Martin B. Integrated Design of a Membrane‐Lytic Peptide‐Based Intravenous Nanotherapeutic Suppresses Triple‐Negative Breast Cancer. Advanced Science. 2105506, 2105506, 2022. [JCR]
Lin JC, Hsu CY, Chen JY, Fang ZS, Chen HW, Yao BY, Shiau GHM, Tsai JS, Gu M, Jung M, Lee TY, Hu CJ. Facile Transformation of Murine and Human Primary Dendritic Cells into Robust and Modular Artificial Antigen-Presenting Systems by Intracellular Hydrogelation. ADVANCED MATERIALS. epub, e2101190, 2021. [JCR]　[WOS]
Huang Ping-Han, Tsai Hsiao-Han, Liao Bo-Hung, Lin Yi-Ling, Jan Jia-Tsrong, Tao Mi-Hua, Chou Yu-Chi, Hu Che-Ming Jack, Chen Hui-Wen. Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain. Human Vaccines & Immunotherapeutics. 17(3): 654-655, 1-2, 2021. [JCR]　[WOS]
Lin Pin-Hung, Liang Chieh-Yu, Yao Bing-Yu, Chen Hui-Wen, Pan Ching-Fu, Wu Li-Ling, Lin Yi-Hsuan, Hsu Yu-Sung, Liu Yu-Han, Chen Pei-Jer, Jack Hu Che-Ming, Yang Hung-Chih. Robust induction of resident memory T cells by combinatorial nanoshells confers cross-strain sterilizing immunity against lethal influenza viruses. Molecular Therapy - Methods & Clinical Development. 21, 299-314, 2021. [JCR]　[WOS]
Lin Shu-Yi, Yao Bing-Yu, Hu Che-Ming Jack, Chen Hui-Wen. Induction of Robust Immune Responses by CpG-ODN-Loaded Hollow Polymeric Nanoparticles for Antiviral and Vaccine Applications in Chickens. International Journal of Nanomedicine. 15,3303-3318, 2020. [JCR]　[WOS]
Chattopadhyay Saborni, Hu Che-Ming Jack. Nanomedicinal delivery of stimulator of interferon genes agonists: recent advances in virus vaccination. Nanomedicine. 15(29), 2883-2894, 2020. [JCR]　[WOS]
Chattopadhyay Saborni, Liu Yu-Han, Fang Zih-Syun, Lin Chi-Long, Lin Jung-Chen, Yao Bing-Yu, Hu Che-Ming Jack. Synthetic Immunogenic Cell Death Mediated by Intracellular Delivery of STING Agonist Nanoshells Enhances Anticancer Chemo-immunotherapy. Nano Letters. 20(4), 2246-2256, 2020. [JCR]　[WOS]
Lin JC, Chien CY, Lin CL, Yao BY, Chen YI, Liu YH, Fang ZS, Chen JY, Chen WY, Lee NN, Chen HW, Hu CJ. Intracellular hydrogelation preserves fluid and functional cell membrane interfaces for biological interactions. Nature communications. 10(1), 1057, 2019-03. [JCR]　[WOS]
Lin Leon Chien‐Wei, Huang Chen‐Yu, Yao Bing‐Yu, Lin Jung‐Chen, Agrawal Anurodh, Algaissi Abdullah, Peng Bi‐Hung, Liu Yu‐Han, Huang Ping‐Han, Juang Rong‐Huay, Chang Yuan‐Chih, Tseng Chien‐Te, Chen Hui‐Wen, Hu Che‐Ming Jack. Viromimetic STING Agonist‐Loaded Hollow Polymeric Nanoparticles for Safe and Effective Vaccination against Middle East Respiratory Syndrome Coronavirus. Advanced Functional Materials. 29(28),, 2019. [JCR]　[WOS]
Liu YH, Kuo SC, Yao BY, Fang ZS, Lee YT, Chang YC, Chen TL, Hu CJ. Colistin nanoparticle assembly by coacervate complexation with polyanionic peptides for treating drug-resistant gram-negative bacteria. Acta biomaterialia. 82, 133-142, 2018-12. [JCR]　[WOS]
Lin Leon Chien-Wei, Chattopadhyay Saborni, Lin Jung-Chen, Hu Che-Ming Jack. Advances and Opportunities in Nanoparticle- and Nanomaterial-Based Vaccines against Bacterial Infections. Advanced Healthcare Materials. 7(13), e1701395, 2018. [JCR]　[WOS]
Hu Che-Ming Jack, Chen You-Ting, Fang Zih-Syun, Chang Wei-Shan, Chen Hui-Wen. Antiviral efficacy of nanoparticulate vacuolar ATPase inhibitors against influenza virus infection. International Journal of Nanomedicine. 13, 8579-8593, 2018. [JCR]　[WOS]
Hu CJ, Chien CY, Liu MT, Fang ZS, Chang SY, Juang RH, Chang SC, Chen HW. Multi-antigen avian influenza a (H7N9) virus-like particles: particulate characterizations and immunogenicity evaluation in murine and avian models. BMC biotechnology. 17(1), 2, 2017. [JCR]　[WOS]
Chattopadhyay S, Chen JY, Chen HW, Hu CJ. Nanoparticle Vaccines Adopting Virus-like Features for Enhanced Immune Potentiation. Nanotheranostics. 1(3), 244-260, 2017. [JCR]
Hu CJ, Chang WS, Fang ZS, Chen YT, Wang WL, Tsai HH, Chueh LL, Takano T, Hohdatsu T, Chen HW. Nanoparticulate vacuolar ATPase blocker exhibits potent host-targeted antiviral activity against feline coronavirus. Scientific reports. 7(1), 13043, 2017. [JCR]　[WOS]
Chen HW, Fang ZS, Chen YT, Chen YI, Yao BY, Cheng JY, Chien CY, Chang YC, Hu CJ. Targeting and Enrichment of Viral Pathogen by Cell Membrane Cloaked Magnetic Nanoparticles for Enhanced Detection. ACS applied materials & interfaces. 9(46), 39953-39961, 2017. [JCR]　[WOS]
Wang F, Fang R, Luk B, Hu C-M, Thamphiwatana S, Dehaini D, Angsantikul P, Kroll A, Pang Z, Gao W, Lu W, Zhang L. Nanoparticle-Based Antivirulence Vaccine for the Management of Methicillin-Resistant Staphylococcus aureus Skin Infection. ADVANCED FUNCTIONAL MATERIALS. 26(10), 1628-1635, 2016-02. [JCR]　[WOS]
Cheng B, Toh EK, Chen KH, Chang YC, Hu CJ, Wu HC, Chau LY, Chen P, Hsieh PC. Biomimicking Platelet-Monocyte Interactions as a Novel Targeting Strategy for Heart Healing. Advanced healthcare materials. 5(20), 2686-2697, 2016. [JCR]　[WOS]
Lin SY, Li YT, Chen YT, Chen TC, Hu CJ, Chen HW. Identification of an infectious bronchitis coronavirus strain exhibiting a classical genotype but altered antigenicity, pathogenicity, and innate immunity profile. Scientific reports. 6, 37725, 2016. [JCR]　[WOS]
Luk BT, Fang RH, Hu CM, Copp JA, Thamphiwatana S, Dehaini D, Gao W, Zhang K, Li S, Zhang L. Safe and Immunocompatible Nanocarriers Cloaked in RBC Membranes for Drug Delivery to Treat Solid Tumors. Theranostics. 6(7), 1004-1011, 2016. [JCR]　[WOS]
Chen HW, Huang CY, Lin SY, Fang ZS, Hsu CH, Lin JC, Chen YI, Yao BY, Hu CM. Synthetic virus-like particles prepared via protein corona formation enable effective vaccination in an avian model of coronavirus infection. Biomaterials. 106, 111-8, 2016. [JCR]　[WOS]
Dehaini D, Fang RH, Luk BT, Pang Z, Hu CM, Kroll AV, Yu CL, Gao W, Zhang L. Ultra-small lipid-polymer hybrid nanoparticles for tumor-penetrating drug delivery. Nanoscale. 8(30), 14411-9, 2016. [JCR]　[WOS]
Pang Z, Hu CM, Fang RH, Luk BT, Gao W, Wang F, Chuluun E, Angsantikul P, Thamphiwatana S, Lu W, Jiang X, Zhang L. Detoxification of Organophosphate Poisoning Using Nanoparticle Bioscavengers. ACS nano. 9(6), 6450-6458, 2015. [JCR]　[WOS]
Fang RH, Luk BT, Hu CM, Zhang L. Engineered nanoparticles mimicking cell membranes for toxin neutralization. Advanced drug delivery reviews. 90, 69-80, 2015. [JCR]　[WOS]
Wang F, Gao W, Thamphiwatana S, Luk BT, Angsantikul P, Zhang Q, Hu CM, Fang RH, Copp JA, Pornpattananangkul D, Lu W, Zhang L. Hydrogel Retaining Toxin-Absorbing Nanosponges for Local Treatment of Methicillin-Resistant Staphylococcus aureus Infection. Advanced materials. 27(22), 3437-3443, 2015. [JCR]　[WOS]
Wang F, Gao W, Thamphiwatana S, Luk BT, Angsantikul P, Zhang Q, Hu CM, Fang RH, Copp JA, Pornpattananangkul D, Lu W, Zhang L. Hydrogel Retaining Toxin-Absorbing Nanosponges for Local Treatment of Methicillin-Resistant Staphylococcus aureus Infection. Advanced materials. 27(22), 3437-3443, 2015. [JCR]　[WOS]
Gao W, Fang RH, Thamphiwatana S, Luk BT, Li J, Angsantikul P, Zhang Q, Hu CM, Zhang L. Modulating antibacterial immunity via bacterial membrane-coated nanoparticles. Nano letters. 15(2), 1403-1409, 2015. [JCR]　[WOS]
Hu CM, Fang RH, Wang KC, Luk BT, Thamphiwatana S, Dehaini D, Nguyen P, Angsantikul P, Wen CH, Kroll AV, Carpenter C, Ramesh M, Qu V, Patel SH, Zhu J, Shi W, Hofman FM, Chen TC, Gao W, Zhang K, Chien S, Zhang L. Nanoparticle biointerfacing by platelet membrane cloaking. Nature. 526(7571), 118-121, 2015. [JCR]　[WOS]
Fang RH, Hu CM, Luk BT, Gao W, Copp JA, Tai Y, O'Connor DE, Zhang L. Cancer cell membrane-coated nanoparticles for anticancer vaccination and drug delivery. Nano letters. 14(4), 2181-2188, 2014. [JCR]　[WOS]
Copp JA, Fang RH, Luk BT, Hu CM, Gao W, Zhang K, Zhang L. Clearance of pathological antibodies using biomimetic nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. 111(37), 13481-13486, 2014. [JCR]　[WOS]
Luk BT, Hu CM, Fang RH, Dehaini D, Carpenter C, Gao W, Zhang L. Interfacial interactions between natural RBC membranes and synthetic polymeric nanoparticles. Nanoscale. 6(5), 2730-2737, 2014. [JCR]　[WOS]
Hu CM, Zhang L. Nanotoxoid Vaccines. Nano today. 9(4), 401-404, 2014. [JCR]　[WOS]
Hu CM, Fang RH, Luk BT, Zhang L. Polymeric nanotherapeutics: clinical development and advances in stealth functionalization strategies. Nanoscale. 6(1), 65-75, 2014. [JCR]　[WOS]
Hu CM, Fang RH, Luk BT, Chen KN, Carpenter C, Gao W, Zhang K, Zhang L. 'Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach. Nanoscale. 5(7), 2664-2668, 2013. [JCR]　[WOS]
Hu CM, Fang RH, Copp J, Luk BT, Zhang L. A biomimetic nanosponge that absorbs pore-forming toxins. Nature nanotechnology. 8(5), 336-340, 2013. [JCR]　[WOS]
Aryal S, Hu CM, Fang RH, Dehaini D, Carpenter C, Zhang DE, Zhang L. Erythrocyte membrane-cloaked polymeric nanoparticles for controlled drug loading and release. Nanomedicine. 8(8), 1271-1280, 2013. [JCR]　[WOS]
Fang RH, Hu CM, Chen KN, Luk BT, Carpenter CW, Gao W, Li S, Zhang DE, Lu W, Zhang L. Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles. Nanoscale. 5(19), 8884-8888, 2013. [JCR]　[WOS]
Gao W, Hu CM, Fang RH, Zhang L. Liposome-like Nanostructures for Drug Delivery. Journal of Materials Chemistry B. 1(48), 6569-6585, 2013. [JCR]　[WOS]
Kong SD, Sartor M, Hu CM, Zhang W, Zhang L, Jin S. Magnetic field activated lipid-polymer hybrid nanoparticles for stimuli-responsive drug release. Acta biomaterialia. 9(3), 5447-5452, 2013. [JCR]　[WOS]
Hu CM, Fang RH, Luk BT, Zhang L. Nanoparticle-detained toxins for safe and effective vaccination. Nature nanotechnology. 8(12), 933-938, 2013. [JCR]　[WOS]
Gao W, Hu CM, Fang RH, Luk BT, Su J, Zhang L. Surface functionalization of gold nanoparticles with red blood cell membranes. Advanced materials. 25(26), 3549-3553, 2013. [JCR]　[WOS]
Hu CM, Fang RH, Zhang L. Erythrocyte-inspired delivery systems. Advanced healthcare materials. 1(5), 537-547, 2012. [JCR]　[WOS]
Fang RH, Chen KN, Aryal S, Hu CM, Zhang K, Zhang L. Large-scale synthesis of lipid-polymer hybrid nanoparticles using a multi-inlet vortex reactor. Langmuir : the ACS journal of surfaces and colloids. 28(39), 13824-13829, 2012. [JCR]　[WOS]
Hu CM, Zhang L. Nanoparticle-based combination therapy toward overcoming drug resistance in cancer. Biochemical pharmacology. 83(8), 1104-1111, 2012. [JCR]　[WOS]
Fang RH, Hu CM, Zhang L. Nanoparticles disguised as red blood cells to evade the immune system. Expert opinion on biological therapy. 12(4), 385-389, 2012. [JCR]　[WOS]
Aryal S, Hu CM, Zhang L. Synthesis of Ptsome: a platinum-based liposome-like nanostructure. Chemical communications. 48(20), 2630-2632, 2012. [JCR]　[WOS]
Hu CM, Zhang L, Aryal S, Cheung C, Fang RH, Zhang L. Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform. Proceedings of the National Academy of Sciences of the United States of America. 108(27), 10980-10985, 2011. [JCR]　[WOS]
Balasubramanian S, Kagan D, Hu CM, Campuzano S, Lobo-Castanon MJ, Lim N, Kang DY, Zimmerman M, Zhang L, Wang J. Micromachine-enabled capture and isolation of cancer cells in complex media. Angewandte Chemie-International Edition. 50(18), 4161-4164, 2011. [JCR]　[WOS]
Aryal S, Hu CM, Zhang L. Polymeric nanoparticles with precise ratiometric control over drug loading for combination therapy. Molecular pharmaceutics. 8(4), 1401-1407, 2011. [JCR]　[WOS]
Lefkowitz RB, Marciniak JY, Hu CM, Schmid-Schonbein GW, Heller MJ. An electrophoretic method for the detection of chymotrypsin and trypsin activity directly in whole blood. Electrophoresis. 31(2), 403-410, 2010. [JCR]　[WOS]
Aryal S, Hu CM, Zhang L. Combinatorial drug conjugation enables nanoparticle dual-drug delivery. Small. 6(13), 1442-1448, 2010. [JCR]　[WOS]
Zhang L, Pornpattananangku D, Hu CM, Huang CM. Development of nanoparticles for antimicrobial drug delivery. Current medicinal chemistry. 17(6), 585-594, 2010. [JCR]　[WOS]
Hu CM, Kaushal S, Tran Cao HS, Aryal S, Sartor M, Esener S, Bouvet M, Zhang L. Half-antibody functionalized lipid-polymer hybrid nanoparticles for targeted drug delivery to carcinoembryonic antigen presenting pancreatic cancer cells. Molecular pharmaceutics. 7(3), 914-920, 2010. [JCR]　[WOS]
Hu CM, Aryal S, Zhang L. Nanoparticle-assisted combination therapies for effective cancer treatment. Therapeutic delivery. 1(2), 323-334, 2010. [JCR]
Aryal S, Hu CM, Zhang L. Polymer--cisplatin conjugate nanoparticles for acid-responsive drug delivery. ACS nano. 4(1), 251-258, 2010. [JCR]　[WOS]
Fang RH, Aryal S, Hu CM, Zhang L. Quick synthesis of lipid-polymer hybrid nanoparticles with low polydispersity using a single-step sonication method. Langmuir : the ACS journal of surfaces and colloids. 26(22), 16958-16962, 2010. [JCR]　[WOS]
Hu CM, Zhang L. Therapeutic nanoparticles to combat cancer drug resistance. Current drug metabolism. 10(8), 836-841, 2009. [JCR]　[WOS]
Baghdasaryan Ofelya, Khan Shahid, Lin Jung-Chen, Lee-Kin Jared, Hsu Chung-Yao, 「Hu Che-Ming Jack*」, Tan Cheemeng*. Synthetic control of living cells by intracellular polymerization. Trends in Biotechnology. , 2023-09-01. [JCR]　[WOS]
Yang Kai-Chieh, Lin Jung-Chen, Tsai Hsiao-Han, Hsu Chung-Yao, Shih Vicky, Hu Che-Ming Jack. Nanotechnology advances in pathogen- and host-targeted antiviral delivery: multipronged therapeutic intervention for pandemic control. Drug Delivery and Translational Research. DOI: 10.1007/s13346-021-00965-y, 2021. [JCR]　[WOS]

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