生命組研究成果
期刊 22
- Pei-Yi (Alma) Su, Chih-Hsu Chang, Shin-Chwen Bruce Yen, Hsiu-Yi Wu, Wan-Ju Tung, Yu-Pei Hu Yen-Yu Ian Chen, Miao-Hsia Lin, Chiaho Shih, Pei-Jer Chen, (Kevin Tsai*). Epitranscriptomic cytidine methylation of the hepatitis B viral RNA is essential for viral reverse transcription and particle production. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 121 (24), e2400378121, 2024-06-03. [JCR] [WOS]
- (Tsai Kevin), Bogerd Hal P., Kennedy Edward M., Emery Ann, Swanstrom Ronald, Cullen Bryan R. Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing. GENES & DEVELOPMENT. 35(13-14), 992-1004, 2021. [JCR] [WOS]
- Martinez Campos C, Tsai K, Courtney DG, Bogerd HP, Holley CL, Cullen BR. Mapping of pseudouridine residues on viral and cellular transcripts using a novel antibody-based technique. RNA (New York, N.Y.). rna.078940.121, 121-121, 2021. [JCR] [WOS]
- (Tsai Kevin), Jaguva Vasudevan Ananda Ayyappan, Martinez Campos Cecilia, Emery Ann, Swanstrom Ronald, Cullen Bryan R. Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability. Cell Host & Microbe. 28(2), 306-312.e6, 2020. [JCR] [WOS]
- (Tsai Kevin), Cullen Bryan R. Epigenetic and epitranscriptomic regulation of viral replication. Nature Reviews Microbiology. 18(10), 559-570, 2020. [JCR] [WOS]
- Irwan Ishak D., Karnowski Heather L., Bogerd Hal P., (Tsai Kevin), Cullen Bryan R. Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function. mBio. 11(3), e01038-20, 2020. [JCR] [WOS]
- Courtney David G., (Tsai Kevin), Bogerd Hal P., Kennedy Edward M., Law Brittany A., Emery Ann, Swanstrom Ronald, Holley Christopher L., Cullen Bryan R. Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression. Cell Host & Microbe. 26(2), 217-227.e6, 2019. [JCR] [WOS]
- (Tsai Kevin), Courtney David G., Cullen Bryan R. Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication. PLOS Pathogens. 14(2), e1006919, 2018. [JCR] [WOS]
- (Tsai K), Courtney DG, Kennedy EM, Cullen BR. Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication. RNA (New York, N.Y.). 24(9), 1172-1182, 2018. [JCR] [WOS]
- Poling Brigid Chiyoko, (Tsai Kevin), Kang Dong, Ren Linda, Kennedy Edward M., Cullen Bryan R. A lentiviral vector bearing a reverse intron demonstrates superior expression of both proteins and microRNAs. RNA Biology. 14(11), 1570-1579, 2017. [JCR] [WOS]
- Courtney DG, Kennedy EM, Dumm RE, Bogerd HP, (Tsai K), Heaton NS, Cullen BR. Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication. Cell host & microbe. 22(3), 377-386.e5, 2017. [JCR] [WOS]
- Kennedy EM, Courtney DG, (Tsai K), Cullen BR. Viral Epitranscriptomics. Journal of virology. 91(9), e02263-16, 2017. [JCR] [WOS]
- Kennedy Edward M., Bogerd Hal P., Kornepati Anand V.R., Kang Dong, Ghoshal Delta, Marshall Joy B., Poling Brigid C., (Tsai Kevin), Gokhale Nandan S., Horner Stacy M., Cullen Bryan R. Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Cell Host & Microbe. 19(5), 675-685, 2016. [JCR] [WOS]
- (Tsai K), Messick TE, Lieberman PM. Disruption of host antiviral resistances by gammaherpesvirus tegument proteins with homology to the FGARAT purine biosynthesis enzyme. Current opinion in virology. 14, 30-40, 2015. [JCR] [WOS]
- Kennedy Edward M., Kornepati Anand V.R., Mefferd Adam L., Marshall Joy B., (Tsai Kevin), Bogerd Hal P., Cullen Bryan R. Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic. Methods. 91, 82-86, 2015. [JCR] [WOS]
- Wang Z, Deng Z, Dahmane N, (Tsai K), Wang P, Williams DR, Kossenkov AV, Showe LC, Zhang R, Huang Q, Conejo-Garcia JR, Lieberman PM. Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes. Proceedings of the National Academy of Sciences of the United States of America. 112(46), E6293-300, 2015. [JCR] [WOS]
- (Tsai K), Chan L, Gibeault R, Conn K, Dheekollu J, Domsic J, Marmorstein R, Schang LM, Lieberman PM. Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection. Journal of virology. 88(24), 14350-63, 2014. [JCR] [WOS]
- Arvey A, Tempera I, (Tsai K), Chen HS, Tikhmyanova N, Klichinsky M, Leslie C, Lieberman PM. An atlas of the Epstein-Barr virus transcriptome and epigenome reveals host-virus regulatory interactions. Cell host & microbe. 12(2), 233-45, 2012. [JCR] [WOS]
- Lu F, (Tsai K), Chen HS, Wikramasinghe P, Davuluri RV, Showe L, Domsic J, Marmorstein R, Lieberman PM. Identification of host-chromosome binding sites and candidate gene targets for Kaposi's sarcoma-associated herpesvirus LANA. Journal of virology. 86(10), 5752-62, 2012. [JCR] [WOS]
- (Tsai K), Thikmyanova N, Wojcechowskyj JA, Delecluse HJ, Lieberman PM. EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription. PLoS pathogens. 7(11), e1002376, 2011. [JCR] [WOS]
- Lu F, Wikramasinghe P, Norseen J, (Tsai K), Wang P, Showe L, Davuluri RV, Lieberman PM. Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1). Virology journal. 7, 262, 2010. [JCR] [WOS]
- Lee Heng-Huan, Chang Shih-Shin, Lin Sue-Jane, Chua Huey-Huey, Tsai Tze-Jiun, (Tsai Kevin), Lo You-Chang, Chen Hong-Chen, Tsai Ching-Hwa. Essential role of PKCδ in histone deacetylase inhibitor-induced Epstein–Barr virus reactivation in nasopharyngeal carcinoma cells. Journal of General Virology. 89(4), 878-883, 2008. [JCR] [WOS]