生命組研究成果
生物醫學科學研究所 - 陳英翰 Chen, Ying Han
期刊 16
- Oyesola O#, Downie AE#, Howard N, Barre RS, Kiwanuka K, Zaldana K, (Chen YH), Menezes A, Lee SC, Devlin J, Mondragon-Palomino O, Souza COS, Herrmann C, Koralov SB, Cadwell K, Graham AL*, Loke P*. Genetic and environmental interactions contribute to immune variation in rewilded mice. Nature immunology. 25(7), 1270-1282, 2024. [JCR] [WOS]
- Liang SH#, Sircaik S#, Dainis J, Kakade P, Penumutchu S, McDonough LD, (Chen YH), Frazer C, Schille TB, Allert S, Elshafee O, Hanel M, Mogavero S, Vaishnava S, Cadwell K, Belenky P, Perez JC, Hube B*, Ene IV, Bennett RJ*. The hyphal-specific toxin candidalysin promotes fungal gut commensalism. Nature. 627(8004), 620-627, 2024.
- Jang KK, Heaney T, London M, Ding Y, Putzel G, Yeung F, Ercelen D, (Chen YH), Axelrad J, Gurunathan S, Zhou C, Podkowik M, Arguelles N, Srivastava A, Shopsin B, Torres VJ, Keestra-Gounder AM, Pironti A, Griffin ME, Hang HC, Cadwell K*. Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization. Cell host & microbe. 31(9), 1450-1468.e8, 2023.
- (Chen YH), Yeung F, Lacey KA, Zaldana K, Lin JD, Bee GCW, McCauley C, Barre RS, Liang SH, Hansen CB, Downie AE, Tio K, Weiser JN, Torres VJ, Bennett RJ, Loke P*, Graham AL*, Cadwell K*. Rewilding of laboratory mice enhances granulopoiesis and immunity through intestinal fungal colonization. Science immunology. 8(84), eadd6910, 2023.
- Downie AE#, Oyesola O#, Barre RS, Caudron Q, (Chen YH), Dennis EJ, Garnier R, Kiwanuka K, Menezes A, Navarrete DJ, Mondragon-Palomino O, Saunders JB, Tokita CK, Zaldana K, Cadwell K, Loke P, Graham AL*. Spatiotemporal-social association predicts immunological similarity in rewilded mice. Science advances. 9(51), eadh8310, 2023.
- (Chen YH), Cadwell K*. Into the wild: How exposure to wild or domesticated fungi shapes immune responses in mice. PLoS pathogens. 18(10), e1010841, 2022.
- Jang KK, Kaczmarek ME, Dallari S, (Chen YH), Tada T, Axelrad J, Landau NR, Stapleford KA, Cadwell K*. Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infection. PLoS biology. 20(3), e3001592, 2022.
- Yeung F#, (Chen YH)#, Lin JD#, Leung JM, McCauley C, Devlin JC, Hansen C, Cronkite A, Stephens Z, Drake-Dunn C, Fulmer Y, Shopsin B, Ruggles KV, Round JL, Loke P,* Graham AL*, Cadwell K*. Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization. Cell host & microbe. 27(5), 809-822.e6, 2020.
- Matsuzawa-Ishimoto Y, Hine A, Shono Y, Rudensky E, Lazrak A, Yeung F, Neil JA, Yao X, (Chen YH), Heaney T, Schuster SL, Zwack EE, Axelrad JE, Hudesman D, Tsai JJ, Nichols K, Dewan MZ, Cammer M, Beal A, Hoffman S, Geddes B, Bertin J, Liu C, Torres VJ, Loke P, van den Brink MRM, Cadwell K*. An intestinal organoid-based platform that recreates susceptibility to T-cell-mediated tissue injury. Blood. 135(26), 2388-2401, 2020.
- Lin JD#, Devlin JC#, Yeung F#, McCauley C, Leung JM, (Chen YH), Cronkite A, Hansen C, Drake-Dunn C, Ruggles KV, Cadwell K*, Graham AL*, Loke P*. Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition. Cell host & microbe. 27(5), 830-840.e4, 2020.
- Oyler-Yaniv J, Oyler-Yaniv A, Shakiba M, Min NK, (Chen YH), Cheng SY, Krichevsky O, Altan-Bonnet N, Altan-Bonnet G*. Catch and Release of Cytokines Mediated by Tumor Phosphatidylserine Converts Transient Exposure into Long-Lived Inflammation. Molecular cell. 66(5), 635-647.e7, 2017.
- Altan-Bonnet N*, (Chen YH). Intercellular Transmission of Viral Populations with Vesicles. Journal of virology. 89(24), 12242-4, 2015.
- (Chen YH), Du W, Hagemeijer MC, Takvorian PM, Pau C, Cali A, Brantner CA, Stempinski ES, Connelly PS, Ma HC, Jiang P, Wimmer E, Altan-Bonnet G, Altan-Bonnet N*. Phosphatidylserine vesicles enable efficient en bloc transmission of enteroviruses. Cell. 160(4), 619-630, 2015.
- Ma HC, Liu Y, Wang C, Strauss M, Rehage N, (Chen YH), Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P*. An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. PLoS pathogens. 10(4), e1004052, 2014.
- Ilnytska O, Santiana M, Hsu NY, Du WL, (Chen YH), Viktorova EG, Belov G, Brinker A, Storch J, Moore C, Dixon JL, Altan-Bonnet N*. Enteroviruses harness the cellular endocytic machinery to remodel the host cell cholesterol landscape for effective viral replication. Cell host & microbe. 14(3), 281-93, 2013.
- Hsu NY, Ilnytska O, Belov G, Santiana M, (Chen YH), Takvorian PM, Pau C, van der Schaar H, Kaushik-Basu N, Balla T, Cameron CE, Ehrenfeld E, van Kuppeveld FJ, Altan-Bonnet N. Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Cell. 141(5), 799-811, 2010.